MCP-1, CCR2 and CCR5 polymorphisms in Tunisian patients with atopic Asthma

Iranian Journal of Allergy, Asthma and Immunology

Volumn 12, Issue 1, 2013, Pages 29-36

  Dhaouadi, Tarak ^a   Sfar, Imen ^a   Aounallah Skhiri, Hajer ^b   Jendoubi Ayed, Saloua ^a   Bouacha, Hend ^a   Abdallah, Taieb Ben ^a   Gorgi, Yousr ^a  

^a CHARLES NICOLLE HOSPITAL   (Tunisia)

^b National Institute of Public Health   (Tunisia)

Author keywords

Asthma; Atopy; Chemokines; MCP 1; Polymorphism

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; GENOMIC DNA; IMMUNOGLOBULIN E; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADOLESCENT; ADULT; ALLERGIC ASTHMA; ARTICLE; CONJUNCTIVITIS; CONTROLLED STUDY; DISEASE SEVERITY; FAMILY HISTORY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PROMOTER REGION; RHINITIS; TUNISIA;

ADOLESCENT; ADULT; ASTHMA; CASE-CONTROL STUDIES; CHEMOKINE CCL2; FEMALE; GENOTYPING TECHNIQUES; HAPLOTYPES; HUMANS; MALE; POLYMORPHISM, GENETIC; RECEPTORS, CCR2; RECEPTORS, CCR5; SEVERITY OF ILLNESS INDEX; TUNISIA;

EID: 84875528983     PISSN: 17351502     EISSN: 17355249     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Marsh DG, Meyers DA, Bias WB. The epidemiology and genetics of atopic allergy. N Engl J Med 1981; 305(26):1551-9. (Pubitemid 12249150)
2. A genome-wide search for asthma susceptibility loci in ethnically diverse populations. The Collaborative Study on the Genetics of Asthma (CGSA). Nat Genet 1997; 15(4):389-92.
3. Koppelman GH, Stine OC, Xu J, Howard TD, Zheng SL, Kauffman HF, et al. Genome-wide search for atopy susceptibility genes in Dutch families with asthma. J Allergy Clin Immunol 2002; 109(3):498-506. (Pubitemid 34234202)
4. Ober C, Tsalenko A, Parry R, Cox NJ. A secondgeneration genomewide screen for asthma susceptibility alleles in a founder population. Am J Hum Genet 2000; 67 (5):1154-62.
5. Dizier MH, Besse-Schmittler C, Guilloud-Bataille M, Annesi-Maesano I, Boussaha M, Bousquet J, et al. Genome screen for asthma and related phenotypes in theFrench EGEA study. Am J Respir Crit Care Med 2000; 162(5):1812-8.
6. Daniels SE, Bhattacharrya S, James A, Leaves NI, Young A, Hill MR, et al. A genome-wide search for quantitative trait loci underlying asthma. Nature 1996; 383(6597):247-50. (Pubitemid 26317671)
7. Hoffjan S, Nicolae D, Ober C. Association studies for asthma and atopic diseases: a comprehensive review of the literature. Respir Res 2003; 4:14-28.
8. Baggiolini M. Chemokines and leukocyte traffic. Nature 1998; 392(6676):565-8. (Pubitemid 28207705)
9. Folkard SG, Westwick J, Millar AB. Production of interkeukin-8, RANTES and MCP-1 in intrinsic and extrinsic asthma. Eur Respir J 1997; 10(9):2097-104. (Pubitemid 27406449)
10. Lukacs NW, Oliveira SH, Hogaboam CM. Chemokines and asthma: redundancyn of function or a coordinated effort? J Clin Invest 1999; 104(8):995-99. (Pubitemid 29536305)
11. Campbell EM., Charo IF, Kunkel SL, Strieter RM, Boring L, Gosling J, et al. Monocyte chemoattractant protein-1 mediates cockroach allergeninducedbronchial hyperreactivity in normal but not CCR2-/-mice: the role of mast cells. J Immunol 1999; 163(4):2160-7. (Pubitemid 29382223)
12. Gonzalo JA, Lloyd CM, Wen D, Albar JP, Wells TN, Proudfoot A, et al. The coordinated action of CC chemokines in the lung orchestrates allergicinflammation and airway hyperresponsiveness. J Exp Med 1998; 188(1):157-67. (Pubitemid 28328614)
13. Rovin BH, Lu L, Saxena R. A novel polymorphism in the MCP-1 generegulatory region that influences MCP-1 expression. Biochem Bioph Res Commun 1999; 259(2):344-8. (Pubitemid 29281234)
14. Mariani R., Wong S, Mulder LC, Wilkinson DA, Reinhart AL, LaRosa G, et al. CCR2-64I polymorphism is not associated with altered CCR5 expression or coreceptor function. J Virol 1999; 73(3):2450-9. (Pubitemid 29098152)
15. Lukacs NW, Strieter RM, Warmington K, Lincoln P, Censue SW, Kunkel SL. Differential recruitment of leukocyte populations and alteration of airway hyperreactivity by C-C family chemokines in allergic airway inflammation. J Immunol 1997; 158(9):4398-404. (Pubitemid 127483943)
16. Teran LM, Noso N, Carrol M, Davies DE, Holgate S, Schroder JM. Eosinophil recruitment following allergen challenge is associated withthe release of the chemokine RANTES into asthmatic airways. J Immunol 1996; 157(4):1808-12.
17. McDermott DH, Zimmerman PA, Guignard F, Kleeberger CA, Leitman SF, Murphy PM. CCR5 promoter polymorphism and HIV-1 disease progression. Multicenter AIDS Cohort Study (MACS). Lancet 1998; 352(9131):866-70. (Pubitemid 28416720)
18. Huang Y, Paxton WA, Wolinsky SM, Neumann AU, Zhang L, He T, et al. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med 1996; 2(11):1240-43. (Pubitemid 26375409)
19. Global Initiative for Asthma. GINA Workshop Report, Global Strategy for Asthma Management and Prevention, April 2002. http://www.ginasthma.com/workshop. pdf.Updated November 2003.http ://www.ginasthma.com/wrclean.pdf.
20. Miller SA, Dykes DD, Polesky HG. A sampling salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988 16 3 1215
21. Sousa AR., Lane SJ, Nakhosteen JA, Yoshimura T, Lee TH, Poston RN. Increased expression of monocyte chemotactic protein-1 in bronchial tissue from asthmatic subjects. Am J Respir Cell Mol Biol 1994; 10(2):142-7.
22. Holgate ST, Bodey KS, Janezic A, Frew AJ, Kaplan AP, Teran LM. Release of RANTES, MIP-1a, and MCP-1 into asthmatic airways following endobronchial allergen challenge. Am J Respir Crit Care Med 1997; 156(5):1377-83. (Pubitemid 27505497)
23. Szalai C, Kozma GT, Nagy A, Bojszkó A, Krikovszky D, Szabó T, et al. Polymorphism in the gene regulatory region of MCP-1 is associated with asthma susceptibility and severity. J Allergy Clin.Immunol 2001; 108(3):375-81. (Pubitemid 32881058)
24. Yao TC, Wu KC, Chung HT, Shaw CK, Kuo ML, Wu CJ, et al. MCP-1 gene regulatory region polymorphism in Chinese children with mild, moderate and near fatal asthma. Allergy 2004; 59(4):436-41.
25. Batra J, Ghosh B. Genetic contribution of chemokine receptor 2 (CCR2) polymorphisms towards increased serum total IgE levels in Indian asthmatics. Genomics 2009; 94(3):161-8.
26. Kim YK, Oh HB, Lee EY, Gho YS, Lee JE, Kim YY. Association between genetic variation of CC chemokine receptor-2 and atopic asthma. Allergy 2007; 62(2):208-9. (Pubitemid 46090305)
27. Abousaidi H, Vazirinejad R, Arababadi MK, Rafatpanah H, Pourfatollah AA, Derakhshan R, et al. Lack of association between chemokine receptor 5 (CCR5)-32 mutation and pathogenesis of asthma in Iranian patients. South Med J 2011; 104(6):422-5.
28. Mitchell TJ, Walley AJ, Pease JE, Venables PJ, Wiltshire S, Williams TJ, et al. Delta 32 deletion of CCR5 gene and association with asthma or atopy. Lancet 2000; 356(9240):1491-2.
29. Srivastava P, Helms PJ, Stewart D, Main M, Russel G. Association of CCR5-32 with reduced risk of childhood but not adult asthma. Thorax 2003; 58(3):222-6. (Pubitemid 36308000)
30. McGinnis R, Child F, Clayton S, Davies S, Lenney W, Illig T, et al. Further support for the association of CCR5 allelic variants with asthma susceptibility. Eur J Immunogenet 2002; 29(6):525-8. (Pubitemid 35365663)
31. Hall IP, Wheatley A, Christie G, McDougall C, Hubbard R, Helms PJ. Association of CCR5-32 with reduced risk of asthma. Lancet 1999; 354(9186):1264-5. (Pubitemid 29469361)