A phosphorescent silver(I)-gold (I) cluster complex that specifically lights up the nucleolus of living cells with FLIM imaging

Biomaterials

Volumn 34, Issue 17, 2013, Pages 4284-4295

  Chen, Min ^a   Lei, Zhen ^b   Feng, Wei ^a   Li, Chunyan ^a   Wang, Quan Ming ^b   Li, Fuyou ^a  

^a FUDAN UNIVERSITY   (China)

^b XIAMEN UNIVERSITY   (China)

Author keywords

FLIM imaging; Nucleolus; Selective staining; Silver(I) gold (I) cluster complex

Indexed keywords

CLUSTER COMPLEXES; ENERGY DEPENDENT; ENERGY DISPERSIVE X-RAY; INDUCTIVELY COUPLED PLASMA ATOMIC EMISSION SPECTROSCOPY; MICROENVIRONMENTS; NUCLEAR MEMBRANES; NUCLEOLUS; SELECTIVE STAINING;

ATOMIC EMISSION SPECTROSCOPY; CELL MEMBRANES; CYTOLOGY; ENZYME ACTIVITY; GOLD; INDUCTIVELY COUPLED PLASMA; PHOSPHORESCENCE; TRANSMISSION ELECTRON MICROSCOPY;

LIGHT EMISSION;

GOLD COMPLEX; SILVER DERIVATIVE;

ARTICLE; ATOMIC EMISSION SPECTROMETRY; CELL CYCLE; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; MICROENVIRONMENT; MICROSCOPY; MOLECULAR STABILITY; NUCLEOLUS; PHOSPHORESCENCE; PRIORITY JOURNAL; STAINING; TIME GATED MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; X RAY ANALYSIS;

BIOLOGICAL TRANSPORT; CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; CELL NUCLEOLUS; CELL SURVIVAL; ENDOCYTOSIS; FLOW CYTOMETRY; GOLD; HUMANS; IMAGING, THREE-DIMENSIONAL; KINETICS; LUMINESCENT MEASUREMENTS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; PHOTOBLEACHING; SILVER; SPECTROPHOTOMETRY, ATOMIC; STAINING AND LABELING; TEMPERATURE;

EID: 84875510979     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.02.032     Document Type: Article

References (41)

1. Boisvert F.M., van Koningsbruggen S., Navascues J., Lamond A.I. The multifunctional nucleolus. Nat Rev Mol Cell Biol 2007, 8:574-585.
2. Lam Y.W., Trinkle M.L., Lamond A.I. The nucleolus. J Cell Sci 2005, 118:1335-1337.
3. Yusupov M.M., Yusupova G.Z., Baucom A., Lieberman K., Earnest T.N., Cate J.H.D., et al. Crystal structure of the ribosome at 5.5 å resolution. Science 2001, 292:883-896.
4. Carmo F.M., Mendes S.L., Campos I. To be or not to be in the nucleolus. Nat Cell Biol 2000, 2:E107-E112.
5. Balakin A.G., Smith L., Fournier M.J. The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions. Cell 1996, 86:823-834.
6. Liu X., Sun Y., Zhang Y., Miao F., Wang G., Zhao H., et al. A 2,7-carbazole-based dicationic salt for fluorescence detection of nucleic acids and two-photon fluorescence imaging of RNA in nucleoli and cytoplasm. Org Biomol Chem 2011, 9:3615-3618.
7. Shen R., Shen X., Zhang Z., Li Y., Liu S., Liu H. Multifunctional conjugates to prepare nucleolar-targeting CdS quantum dots. J Am Chem Soc 2010, 132:8627-8634.
8. Haulgland R.P. Assays for cell viability, proliferation and function. In the handbook, a guide to fluorescent probe and labeling technologies 2005, 710-711. Invitrogen, Molecular Probes, Eugene, Oregon. 10th ed. M.T.Z. Spence (Ed.).
9. You Y., Lee S., Kim T., Ohkubo K., Chae W.S., Fukuzumi S., et al. Phosphorescent sensor for biological mobile zinc. J Am Chem Soc 2011, 133:18328-18342.
10. Botchway S.W., Charnley M., Haycock J.W., Parker A.W., Rochester D.L., Weinstein J.A., et al. Time-resolved and two-photon emission imaging microscopy of live cells with inert platinum complexes. Proc Nat Acad Sci 2008, 105:16071-16076.
11. Kuimova M.K., Yahioglu G., Levitt J.A., Suhling K. Molecular rotor measures viscosity of live cells via fluorescence lifetime imaging. J Am Chem Soc 2008, 130:6672-6673.
12. Gratton E., Breusegem S., Sutin J., Ruan Q., Barry N. Fluorescence lifetime imaging for the two-photon microscope: time-domain and frequency-domain methods. J Biomed Opt 2003, 8:381-390.
13. Svensson F.R., Abrahamsson M., Stromberg N., Ewing A.G., Lincoln P. Ruthenium(II) complex enantiomers as cellular probes for diastereomeric interactions in confocal and fluorescence lifetime imaging microscopy. J Phys Chem Lett 2011, 2:397-401.
14. Tadrous P.J. Methods for imaging the structure and function of living tissues and cells: 2. fluorescence lifetime imaging. J Pathol 2000, 191:229-234.
15. Zhang J., Fu Y., Lakowicz J.R. Fluorescent metal nanoshells: lifetime-tunable molecular probes in fluorescent cell imaging. J Phys Chem C 2011, 115:7255-7260.
16. Zhao Q., Huang C.H., Li F.Y. Phosphorescent heavy-metal complexes for bioimaging. Chem Soc Rev 2011, 40:2508-2524.
17. Lo K.K.W., Tsang K.H.K., Sze K.S., Chung C.K., Lee T.K.M., Zhang K.Y., et al. Non-covalent binding of luminescent transition metal polypyridine complexes to avidin, indole-binding proteins and estrogen receptors. Coord Chem Rev 2007, 251:2292-2310.
18. Baggaley E., Weinstein J.A., Williams J.A.G. Lighting the way to see inside the live cell with luminescent transition metal complexes. Coord Chem Rev 2012, 256:1762-1785.
19. Leung S.K., Kwok K.Y., Zhang K.Y., Lo K.K.W. Design of luminescent biotinylation reagents derived from cyclometalated iridium(III) and rhodium(III) bis(pyridylbenzaldehyde) complexes. Inorg Chem 2010, 49:4984-4995.
20. Lo K.K.W., Choi A.W.T., Law W.H.T. Applications of luminescent inorganic and organometallic transition metal complexes as biomolecular and cellular probes. Dalton Trans 2012, 41:6021-6047.
21. Lo K.K.W., Li S.P.Y., Zhang K.Y. Development of luminescent iridium(III) polypyridine complexes as chemical and biological probes. New J Chem 2011, 35:265-287.
22. Leung S.K., Liu H.W., Lo K.K.W. Functionalization of luminescent cyclometalated iridium(III) polypyridine complexes with a fluorous moiety: photophysics, protein-binding, bioconjugation, and cellular uptake properties. Chem Commun 2011, 47:10548-10550.
23. Kumar R., Ohulchanskyy T., Turowski S., Thompson M., Seshadri M., Prasad P. Combined magnetic resonance and optical imaging of head and neck tumor xenografts using gadolinium-labelled phosphorescent polymeric nanomicelles. Head Neck 2010, 2:35.
24. Koo C.K., So L.K.Y., Wong K.L., Ho Y.M., Lam Y.W., Lam M.H.W., et al. A triphenylphosphonium-functionalised cyclometalated platinum(II) complex as a nucleolus-specific two-photon molecular dye. Chem Eur J 2010, 16:3942-3950.
25. Yu J., Parker D., Pal R., Poole R.A., Cann M.J. A europium complex that selectively stains nucleoli of cells. J Am Chem Soc 2006, 128:2294-2299.
26. New E.J., Congreve A., Parker D. Definition of the uptake mechanism and sub-cellular localisation profile of emissive lanthanide complexes as cellular optical probes. Chem Sci 2010, 1:111-118.
27. Montgomery C.P., Murray B.S., New E.J., Pal R., Parker D. Cell-penetrating metal complex optical probes: targeted and responsive systems based on lanthanide luminescence. Acc Chem Res 2009, 42:925-937.
28. Crocker J., Nar P. Nucleolar organizer regions in lymphomas. J Path 1987, 151:111-118.
29. De Capoa A., Ferraro M., Lavia P., Pelliccia F., Finazzi-Agrò A. Silver staining of the nucleolus organizer regions (NOR) requires clusters of sulfhydryl groups. J Histochem Cytochem 1982, 30:908-911.
30. Heukeshoven J., Dernick R. Simplified method for silver staining of proteins in polyacrylamide gels and the mechanism of silver staining. Electrophoresis 1985, 6:103-112.
31. Fernandez-Piqueras J., Castaño C.S., Garcia E.R., Campos A.R. An acidic silver staining method for synaptonemal complexes under light microscopy. J Microsc 1984, 133:99-102.
32. Buchwalow I., Böcker W. Probes for staining specific cellular organelles. Immunohistochemistry: basics and methods 2010, 83-94. Springer Berlin Heidelberg.
33. Gos T., Krell D., Bielau H., Steiner J., Mawrin C., Trübner K., et al. Demonstration of disturbed activity of the lateral amygdaloid nucleus projection neurons in depressed patients by the AgNOR staining method. J Affect Disord 2010, 126:402-410.
34. Jia J.H., Wang Q.M. Intensely luminescent gold(I)-silver(I) cluster with hypercoordinated carbon. J Am Chem Soc 2009, 131:16634-16635.
35. Puckett C.A., Barton J.K. Mechanism of cellular uptake of a ruthenium polypyridyl complex. Biochemistry 2008, 47:11711-11716.
36. Li C., Yu M., Sun Y., Wu Y., Huang C., Li F. A nonemissive iridium(III) complex that specifically lights-up the nuclei of living cells. J Am Chem Soc 2011, 133:11231-11239.
37. Krishan A. Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. J Cell Biol 1975, 66:188-193.
38. Sakaue S.A., Kurokawa H., Morimura T., Hanyu A., Hama H., Osawa H., et al. Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell 2008, 132:487-498.
39. Darzynkiewicz Z., Bedner E., Smolewski P. Flow cytometry in analysis of cell cycle and apoptosis. Semin Hematol 2001, 38:179-193.
40. Shiang Y.C., Huang C.C., Chen W.Y., Chen P.C., Chang H.T. Fluorescent gold and silver nanoclusters for the analysis of biopolymers and cell imaging. J Mater Chem 2012, 22:12972-12982.
41. Xie F., Drozdowicz T.K., Shtoyko T., Goldys E. Silver and gold nanoparticle coated membranes applied to protein dot blots. J Nanopart Res 2011, 13:613-624.