Separation and characterisation of beta2-microglobulin folding conformers by ion-exchange liquid chromatography and ion-exchange liquid chromatography-mass spectrometry

Analytica Chimica Acta

Volumn 771, Issue , 2013, Pages 108-114

  Bertoletti, Laura ^a   Regazzoni, Luca ^b   Aldini, Giancarlo ^b   Colombo, Raffaella ^a   Abballe, Franco ^c   Caccialanza, Gabriele ^a   De Lorenzi, Ersilia ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c Thermo Fisher Scientific   (United States)

Author keywords

2 m; Amyloidosis; Beta2 microglobulin; CSD; Ion exchange chromatography; Mass spectrometry; Protein conformers; Protein folding

Indexed keywords

AMYLOIDOSIS; BETA2-MICROGLOBULIN; CHARGE STATE DISTRIBUTION; CHROMATOGRAPHIC METHODS; CSD; ION-EXCHANGE CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MOBILE PHASE CONDITIONS;

CAPILLARY ELECTROPHORESIS; CHROMATOGRAPHIC ANALYSIS; IONS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEIN FOLDING; PROTEINS; SEPARATION;

ION EXCHANGE;

BETA 2 MICROGLOBULIN;

ARTICLE; ION EXCHANGE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN UNFOLDING; SEPARATION TECHNIQUE; ULTRAVIOLET RADIATION; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; ION EXCHANGE CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METHODOLOGY;

BETA 2-MICROGLOBULIN; CHROMATOGRAPHY, ION EXCHANGE; MASS SPECTROMETRY; PROTEIN CONFORMATION; PROTEIN FOLDING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84875484637     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2013.01.058     Document Type: Article

References (33)

1. Chiti F., Dobson C.M. Annu. Rev. Biochem. 2006, 75:333-366.
2. Dobson C.M. Nat. Struct. Mol. Biol. 2006, 13:295-297.
3. Jahn T.R., Parker M.J., Homans S.W., Radford S.E. Nat. Struct. Mol. Biol. 2006, 13:195-201.
4. Eichner T., Radford S.E. FEBS J. 2011, 278:3868-3883.
5. Radford S.E., Gosal W.S., Platt G.W. Biochim. Biophys. Acta 2005, 1753:51-63.
6. Platt G.W., Radford S.E. FEBS Lett. 2009, 583:2623-2629.
7. Chiti F., Mangione P., Andreola A., Giorgetti S., Stefani M., Dobson C.M., Bellotti V., Taddei N. J. Mol. Biol. 2001, 307:379-391.
8. Trinh C.H., Smith D.P., Kalverda A.P., Phillips S.E.V., Radford S.E. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:9771-9776.
9. Verdone G., Corazza A., Viglino P., Pettirossi F., Giorgetti S., Mangione P., Andreola A., Stoppini M., Bellotti V., Esposito G. Protein Sci. 2002, 11:487-499.
10. Corazza A., Rennella E., Schanda P., Mimmi M.C., Cutuil T., Raimondi S., Giorgetti S., Fogolari F., Viglino P., Frydman L., Gal M., Bellotti V., Brutscher B., Esposito G. J. Biol. Chem. 2010, 285:5827-5835.
11. Kameda A., Hoshino M., Higurashi T., Takahashi S., Naiki H., Goto Y. J. Mol. Biol. 2005, 348:383-397.
12. Borysik A.J.H., Radford S.E., Ashcroft A.E. J. Biol. Chem. 2004, 279:27069-27077.
13. Borysik A.J.H., Read P., Little D.R., Bateman R.H., Radford S.E., Ashcroft A.E. Rapid Commun. Mass Spectrom. 2004, 18:2229-2234.
14. Smith D.P., Giles K., Bateman R.H., Radford S.E., Ashcroft A.E. J. Am. Soc. Mass Spectrom. 2007, 18:2180-2190.
15. Fogolari F., Corazza A., Varini N., Rotter M., Gumral D., Codutti L., Rennella E., Viglino P., Bellotti V., Esposito G. Proteins 2010, 79:986-1001.
16. Corazza A., Pettirossi F., Viglino P., Verdone G., Garcia J., Dumy P., Giorgetti S., Mangione P., Raimondi S., Stoppini M., Bellotti V., Esposito G. J. Biol. Chem. 2004, 279:9176-9189.
17. Sakata M., Chatani E., Kameda A., Sakurai K., Naiki H., Goto Y. J. Mol. Biol. 2008, 382:1242-1255.
18. Kameda A., Morita E.-H., Sakurai K., Naiki H., Goto Y. Protein Sci. 2009, 18:1592-1601.
19. Eichner T., Radford S.E. J. Mol. Biol. 2009, 386:1312-1326.
20. Chiti F., De Lorenzi E., Grossi S., Mangione P., Giorgetti S., Caccialanza G., Dobson C.M., Merlini G., Ramponi G., Bellotti V. J. Biol. Chem. 2001, 276:46714-46721.
21. Heegaard N.H.H., De Lorenzi E. Biochim. Biophys. Acta 2005, 1753:131-140.
22. Carazzone C., Colombo R., Quaglia M., Mangione P., Raimondi S., Giorgetti S., Caccialanza G., Bellotti V., De Lorenzi E. Electrophoresis 2008, 29:1502-1510.
23. De Lorenzi E., Colombo R., Sabella S., Corlin D.B., Heegaard N.H.H. Electrophoresis 2008, 29:1734-1740.
24. De Lorenzi E., Grossi S., Massolini G., Giorgetti S., Mangione P., Andreola A., Chiti F., Bellotti V., Caccialanza G. Electrophoresis 2002, 23:918-925.
25. Quaglia M., Carazzone C., Sabella S., Colombo R., Giorgetti S., Bellotti V., De Lorenzi E. Electrophoresis 2005, 26:4055-4063.
26. Regazzoni L., Bertoletti L., Vistoli G., Colombo R., Aldini G., Serra M., Carini M., Caccialanza G., De Lorenzi E. ChemMedChem 2010, 5:1015-1025.
27. Regazzoni L., Colombo R., Bertoletti L., Vistoli G., Aldini G., Serra M., Carini M., Maffei Facino R., Giorgetti S., Stoppini M., Caccialanza G., De Lorenzi E. Anal. Chim. Acta 2011, 685:153-161.
28. Hilser V.J., Freire E. Anal. Biochem. 1995, 224:465-485.
29. Heegaard N.H.H., Rovatti L., Nissen M.H., Hamdan M. J. Chromatogr. A 2003, 1004:51-59.
30. Esposito G., Michelutti R., Verdone G., Viglino P., Hernández H., Robinson C.V., Amoresano A., Dal Piaz F., Monti M., Pucci P., Mangione P., Stoppini M., Merlini G., Ferri G., Bellotti V. Protein Sci. 2000, 9:831-845.
31. Keller B.O., Sui J., Young A.B., Whittal R.M. Anal. Chim. Acta 2008, 627:71-81.
32. Chiti F., Dobson C.M. Nat. Chem. Biol. 2009, 5:15-22.
33. Eyles S.J., Kaltashov I.A. Methods 2004, 34:88-99.