메뉴 건너뛰기




Volumn 8, Issue 3, 2013, Pages

The Dynamic Right-to-Left Translocation of Cerl2 Is Involved in the Regulation and Termination of Nodal Activity in the Mouse Node

Author keywords

[No Author keywords available]

Indexed keywords

CERL2 PROTEIN; LEFT RIGHT DETERMINATION FACTOR; MESSENGER RNA; PROTEIN LEFTY1; PROTEIN NODAL; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84875470948     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060406     Document Type: Article
Times cited : (27)

References (33)
  • 2
    • 33645110732 scopus 로고    scopus 로고
    • Left-right asymmetry in the vertebrate embryo: from early information to higher-level integration
    • Raya A, Belmonte JC, (2006) Left-right asymmetry in the vertebrate embryo: from early information to higher-level integration. Nature Reviews Genetics 7: 283-293.
    • (2006) Nature Reviews Genetics , vol.7 , pp. 283-293
    • Raya, A.1    Belmonte, J.C.2
  • 3
    • 33947656333 scopus 로고    scopus 로고
    • Nodal signaling: developmental roles and regulation
    • Shen MM, (2007) Nodal signaling: developmental roles and regulation. Development 134: 1023-1034.
    • (2007) Development , vol.134 , pp. 1023-1034
    • Shen, M.M.1
  • 4
    • 28244501046 scopus 로고    scopus 로고
    • Left-right asymmetry and cogenital cardiac defects: getting to the heart of the matter in vertebrate left-right axis determination
    • Ramsdell AF, (2005) Left-right asymmetry and cogenital cardiac defects: getting to the heart of the matter in vertebrate left-right axis determination. Developmental Biology 288: 1-20.
    • (2005) Developmental Biology , vol.288 , pp. 1-20
    • Ramsdell, A.F.1
  • 5
    • 34249867967 scopus 로고    scopus 로고
    • Heterotaxia, congenital heart disease, and primary ciliary dyskinesia
    • Brueckner M, (2007) Heterotaxia, congenital heart disease, and primary ciliary dyskinesia. Circulation 115: 2793-2795.
    • (2007) Circulation , vol.115 , pp. 2793-2795
    • Brueckner, M.1
  • 6
    • 33646204913 scopus 로고    scopus 로고
    • Nodal flow and the generation of the left-right asymmetry
    • Hirokawa N, Tanaka Y, Okada Y, Takeda S, (2006) Nodal flow and the generation of the left-right asymmetry. Cell 125: 35-45.
    • (2006) Cell , vol.125 , pp. 35-45
    • Hirokawa, N.1    Tanaka, Y.2    Okada, Y.3    Takeda, S.4
  • 8
    • 0035433724 scopus 로고    scopus 로고
    • Mechanisms of the left-right asymmetry: What's right and what's left
    • Wright C V, (2001) Mechanisms of the left-right asymmetry: What's right and what's left? Developmental Cell 1: 179-186.
    • (2001) Developmental Cell , vol.1 , pp. 179-186
    • Wright, C.V.1
  • 9
    • 0037106188 scopus 로고    scopus 로고
    • Nodal activity in the node governs left-right asymmetry
    • Brennan J, Norris DP, Robertson EJ, (2002) Nodal activity in the node governs left-right asymmetry. Genes & Development 16: 2339-2344.
    • (2002) Genes & Development , vol.16 , pp. 2339-2344
    • Brennan, J.1    Norris, D.P.2    Robertson, E.J.3
  • 10
    • 0037377604 scopus 로고    scopus 로고
    • Left-right patterning of the mouse lateral plate requires nodal produced in the node
    • Saijoh Y, Oki S, Hamada H, (2003) Left-right patterning of the mouse lateral plate requires nodal produced in the node. Developmental Biology 256: 161-173.
    • (2003) Developmental Biology , vol.256 , pp. 161-173
    • Saijoh, Y.1    Oki, S.2    Hamada, H.3
  • 11
    • 36549035731 scopus 로고    scopus 로고
    • Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo
    • Oki S, Hashimoto R, Okui Y, Shen MM, Mekada E, et al. (2007) Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo. Development 134: 3893-3904.
    • (2007) Development , vol.134 , pp. 3893-3904
    • Oki, S.1    Hashimoto, R.2    Okui, Y.3    Shen, M.M.4    Mekada, E.5
  • 12
    • 33745612029 scopus 로고    scopus 로고
    • The left-right axis in the mouse: from origen to morphology
    • Shiratori H, Hamada H, (2006) The left-right axis in the mouse: from origen to morphology. Development 133: 2095-2104.
    • (2006) Development , vol.133 , pp. 2095-2104
    • Shiratori, H.1    Hamada, H.2
  • 14
    • 4644289915 scopus 로고    scopus 로고
    • The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis
    • Marques S, Borges AC, Silva AC, Freitas S, Cordenonsi M, et al. (2004) The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis. Genes & Development 18: 2342-2347.
    • (2004) Genes & Development , vol.18 , pp. 2342-2347
    • Marques, S.1    Borges, A.C.2    Silva, A.C.3    Freitas, S.4    Cordenonsi, M.5
  • 15
    • 19344367605 scopus 로고    scopus 로고
    • Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination
    • Okada Y, Takeda S, Tanaka Y, Belmonte JC, Hirokawa N, (2005) Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination. Cell 121: 633-644.
    • (2005) Cell , vol.121 , pp. 633-644
    • Okada, Y.1    Takeda, S.2    Tanaka, Y.3    Belmonte, J.C.4    Hirokawa, N.5
  • 16
    • 0032493876 scopus 로고    scopus 로고
    • Lefty-1 is required for left-right determination as regulator of the lefty-2 and nodal
    • Meno C, Shimono A, Saijoh Y, Yashiro K, Mochida K, et al. (1998) Lefty-1 is required for left-right determination as regulator of the lefty-2 and nodal. Cell 94: 287-297.
    • (1998) Cell , vol.94 , pp. 287-297
    • Meno, C.1    Shimono, A.2    Saijoh, Y.3    Yashiro, K.4    Mochida, K.5
  • 17
    • 0031436570 scopus 로고    scopus 로고
    • Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula
    • Belo JA, Bouwmeester T, Leyns L, Ketersz N, Gallo M, et al. (1997) Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. Mechanisms of Development 68: 45-57.
    • (1997) Mechanisms of Development , vol.68 , pp. 45-57
    • Belo, J.A.1    Bouwmeester, T.2    Leyns, L.3    Ketersz, N.4    Gallo, M.5
  • 18
    • 0036275653 scopus 로고    scopus 로고
    • Dual Roles of Cripto as a Ligand and Coreceptor in the Nodal Signaling Pathway
    • Yan Y, Liu J, Luo Y, Chaosu E, Haltiwanger RS, et al. (2002) Dual Roles of Cripto as a Ligand and Coreceptor in the Nodal Signaling Pathway. Molecular and Cellular Biology 22: 4439-4449.
    • (2002) Molecular and Cellular Biology , vol.22 , pp. 4439-4449
    • Yan, Y.1    Liu, J.2    Luo, Y.3    Chaosu, E.4    Haltiwanger, R.S.5
  • 19
    • 0034075654 scopus 로고    scopus 로고
    • Form and function: the laminin family of the heterotrimers
    • Colognato H, Yurchenco PD, (2000) Form and function: the laminin family of the heterotrimers. Developmental Dynamics 218: 213-234.
    • (2000) Developmental Dynamics , vol.218 , pp. 213-234
    • Colognato, H.1    Yurchenco, P.D.2
  • 20
    • 0033212985 scopus 로고    scopus 로고
    • Abnormal nodal flow precedes situs inversus in the in and inv mice
    • Okada Y, Nonaka S, Tanaka Y, Saijoh Y, Hamada H, et al. (1999) Abnormal nodal flow precedes situs inversus in the in and inv mice. Molecular Cell 4: 459-468.
    • (1999) Molecular Cell , vol.4 , pp. 459-468
    • Okada, Y.1    Nonaka, S.2    Tanaka, Y.3    Saijoh, Y.4    Hamada, H.5
  • 21
    • 84856729595 scopus 로고    scopus 로고
    • Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo
    • Shinohara K, Kawasumi A, Takamatsu A, Yoshiba S, Botilde Y, et al. (2012) Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo. Nature Communications 3: 622.
    • (2012) Nature Communications , vol.3 , pp. 622
    • Shinohara, K.1    Kawasumi, A.2    Takamatsu, A.3    Yoshiba, S.4    Botilde, Y.5
  • 22
    • 70450203077 scopus 로고    scopus 로고
    • Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos
    • Oki S, Kitajima K, Marques S, Belo JA, Yokoyama T, et al. (2009) Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos. Development 136: 3917-3925.
    • (2009) Development , vol.136 , pp. 3917-3925
    • Oki, S.1    Kitajima, K.2    Marques, S.3    Belo, J.A.4    Yokoyama, T.5
  • 23
    • 84861658501 scopus 로고    scopus 로고
    • Defective Nodal and Cerl2 expression in the Arl13bhnn mutant node underlie its heterotaxia
    • Larkins CE, Long AB, Caspary T, (2012) Defective Nodal and Cerl2 expression in the Arl13bhnn mutant node underlie its heterotaxia. Developmental Biology 367: 15-24.
    • (2012) Developmental Biology , vol.367 , pp. 15-24
    • Larkins, C.E.1    Long, A.B.2    Caspary, T.3
  • 24
    • 79955007799 scopus 로고    scopus 로고
    • Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of the mouse embryos
    • Kawasumi A, Nakamura T, Iwai N, Yashiro K, Saijoh Y, et al. (2011) Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of the mouse embryos. Developmental Biology 353: 321-330.
    • (2011) Developmental Biology , vol.353 , pp. 321-330
    • Kawasumi, A.1    Nakamura, T.2    Iwai, N.3    Yashiro, K.4    Saijoh, Y.5
  • 25
    • 0030690337 scopus 로고    scopus 로고
    • Dual role of the Smad4/DPC4 tumor suppressor in the TGFβ signals
    • Liu F, Pouponnot C, Massagué J, (1997) Dual role of the Smad4/DPC4 tumor suppressor in the TGFβ signals. Genes & Development 11: 3157-3167.
    • (1997) Genes & Development , vol.11 , pp. 3157-3167
    • Liu, F.1    Pouponnot, C.2    Massagué, J.3
  • 26
    • 33846911075 scopus 로고    scopus 로고
    • The left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryos
    • Vonica A, Brivanlou AH, (2007) The left-right axis is regulated by the interplay of Coco, Xnr1 and derrière in Xenopus embryos. Developmental Biology 303: 281-294.
    • (2007) Developmental Biology , vol.303 , pp. 281-294
    • Vonica, A.1    Brivanlou, A.H.2
  • 27
    • 33749042595 scopus 로고    scopus 로고
    • Generation of robust left-right asymmetry in the mouse embryo requires a Self-Enhancement and Lateral-Inhibition system
    • Nakamura T, Mine N, Nakaguchi E, Mochizuchi A, Yamamoto M, et al. (2006) Generation of robust left-right asymmetry in the mouse embryo requires a Self-Enhancement and Lateral-Inhibition system. Developmental Cell 11: 495-504.
    • (2006) Developmental Cell , vol.11 , pp. 495-504
    • Nakamura, T.1    Mine, N.2    Nakaguchi, E.3    Mochizuchi, A.4    Yamamoto, M.5
  • 28
    • 34250824668 scopus 로고    scopus 로고
    • Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo
    • Tavares AT, Andrade S, Silva AC, Belo JA, (2007) Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo. Development 134: 2051-2060.
    • (2007) Development , vol.134 , pp. 2051-2060
    • Tavares, A.T.1    Andrade, S.2    Silva, A.C.3    Belo, J.A.4
  • 29
    • 77951205996 scopus 로고    scopus 로고
    • The nodal inhibitor Coco is a critical target of leftward flow in Xenopus
    • Schweickert A, Vick P, Getwan M, Weber T, Schneider I, et al. (2010) The nodal inhibitor Coco is a critical target of leftward flow in Xenopus. Current Biology 20: 738-743.
    • (2010) Current Biology , vol.20 , pp. 738-743
    • Schweickert, A.1    Vick, P.2    Getwan, M.3    Weber, T.4    Schneider, I.5
  • 30
    • 17244366458 scopus 로고    scopus 로고
    • Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut
    • Essner JJ, Amack JD, Nyholm MK, Harris EB, Yost HJ, (2005) Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut. Development 132: 1247-1260.
    • (2005) Development , vol.132 , pp. 1247-1260
    • Essner, J.J.1    Amack, J.D.2    Nyholm, M.K.3    Harris, E.B.4    Yost, H.J.5
  • 31
    • 0032428685 scopus 로고    scopus 로고
    • Randomization of the left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein
    • Nonaka S, Tanaka Y, Okada Y, Takeda S, Harada A, et al. (1998) Randomization of the left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95: 829-837.
    • (1998) Cell , vol.95 , pp. 829-837
    • Nonaka, S.1    Tanaka, Y.2    Okada, Y.3    Takeda, S.4    Harada, A.5
  • 33
    • 84871747038 scopus 로고    scopus 로고
    • Fluid Flow and Interlinked Feedback Loops Establish Left-Right Asymmetric Decay of Cerl2 mRNA in the Mouse Embryo
    • Nakamura T, Saito D, Kawasumi A, Shinohara K, Takaoka K, et al. (2012) Fluid Flow and Interlinked Feedback Loops Establish Left-Right Asymmetric Decay of Cerl2 mRNA in the Mouse Embryo. Nature Communications 3: 1322.
    • (2012) Nature Communications , vol.3 , pp. 1322
    • Nakamura, T.1    Saito, D.2    Kawasumi, A.3    Shinohara, K.4    Takaoka, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.