Mechanisms of Left-Right Asymmetry: What's Right and What's Left?

Developmental Cell

Volumn 1, Issue 2, 2001, Pages 179-186

  Wright, Christopher V E ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; INVS PROTEIN, HUMAN; INVS PROTEIN, MOUSE; PROTEIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; BIOLOGICAL MODEL; CHICK EMBRYO; CONFERENCE PAPER; EVOLUTION; HEMISPHERIC DOMINANCE; HUMAN; METABOLISM; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION; ZEBRA FISH;

ACTIVINS; ANIMALS; CHICK EMBRYO; DOMINANCE, CEREBRAL; EVOLUTION; FUNCTIONAL LATERALITY; HUMANS; MICE; MODELS, BIOLOGICAL; PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; ZEBRAFISH;

EID: 0035433724     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(01)00036-3     Document Type: Article

References (22)

1. Bisgrove, B.W., Essner, J.J., and Yost, H.J. (2000). Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry. Development 127, 3567-3579.
2. Bock, G.R., and Marsh, J. (eds.) (1991). Biological asymmetry and handedness. Ciba foundation symposium 162: Portland Press.
3. Capdevila, J., Vogan, K.J., Tabin, C.J., and Izpisúa Belmonte, J.C. (2000). Mechanisms of left-right determination in vertebrates. Cell 101, 9-21.
4. Chen, Y., and Schier, A.F. (2001). The zebrafish Nodal signal Squint functions as a morphogen. Nature 411, 607-610.
5. Concha, M.L., Burdine, R.D., Russell, C., Schier, A.F., and Wilson, S.W. (2001). A nodal signaling pathway regulates the laterality of neuroanatomical asymmetries in the zebrafish forebrain. Neuron 28, 399-409.
6. Hyatt, B.A., and Yost, H.J. (1998). The left-right coordinator: the role of Vg1 in organizing left-right axis formation. Cell 93, 37-46.
7. Levin, M., and Mercola, M. (1998). The compulsion of chirality: toward an understanding of left-right asymmetry. Genes Dev. 12, 763-769.
8. Levin, M., and Mercola, M. (1999). Gap junction-mediated transfer of left-right patterning signals in the early chick blastoderm is upstream of the Shh asymmetry in the node. Development 126, 4703-4714.
9. Levin, M., Johnson, R.L., Stern, C.D., Kuehn, M., and Tabin, C. (1995). A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell 82, 803-814.
10. Liang, J.O., Etheridge, A., Hantsoo, L., Rubinstein, A.L., Nowak, S.J., Izpisúa Belmonte, J.C., and Halpern, M.E. (2000). Asymmetric nodal signaling in the zebrafish diencephalon positions the pineal organ. Development 127, 5101-5112.
11. Lowe, L.A., Yamada, S., and Kuehn, M.R. (2001). Genetic dissection of nodal function in patterning the mouse embryo. Development 128, 1831-1843.
12. Meno, C., Takeuchi, J., Sakuma, R., Koshiba-Takeuchi, K., Ohishi, S., Saijoh, Y., Miyazaki, J., ten Dijke, P., Ogura, T., and Hamada, H. (2001). Diffusion of Nodal signaling activity in the absence of the feedback inhibitor Lefty2. Dev. Cell 1, 127-138.
13. Monsoro-Burq, A., and Le Douarin, N.M. (2001). BMP4 plays a key role in left-right patterning in chick embryos by maintaining Sonic Hedgehog asymmetry. Mol. Cell 7, 789-799.
14. Okada, Y., Nonaka, S., Tanaka, Y., Saijoh, Y., Hamada, H., and Hirokawa, N. (1999). Abnormal nodal flow precedes situs inversus in iv and inv mice. Mol. Cell 4, 459-468.
15. Rebagliati, M.R., Toyama, R., Fricke, C., Haffter, P., and Dawid, I.B. (1998). Zebrafish nodal-related genes are implicated in axial patterning and establishing left-right asymmetry. Dev. Biol. 199, 261-272.
16. Sampath, K., Rubinstein, A.L., Cheng, A.M., Liang, J.O., Fekany, K., Solnica-Krezel, L., Korzh, V., Halpern, M.E., and Wright, C.V. (1998). Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling. Nature 395, 185-189.
17. Supp, D.M., Witte, D.P., Potter, S.S., and Brueckner, M. (1997). Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice. Nature 389, 963-966.
18. Thisse, C., and Thisse, B. (1999). Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction. Development 126, 229-240.
19. Yan, Y.T., Gritsman, K., Ding, J., Burdine, R.D., Corrales, J.D., Price, S.M., Talbot, W.S., Schier, A.F., and Shen, M.M. (1999). Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation. Genes Dev. 13, 2527-2537.
20. Yasui, K., Zhang, S., Uemura, M., and Saiga, H. (2000). Left-right asymmetric expression of BbPtx, a Ptx-related gene, in a lancelet species and the developmental left-sidedness in deuterostomes. Development 127, 187-195.
21. Yeo, C., and Whitman, M. (2001). Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms. Mol. Cell 7, 949-957.
22. Zhang, X.M., Ramalho-Santos, M., and McMahon, A.P. (2001). Smoothened mutants reveal redundant roles for shh and ihh signaling including regulation of l/r asymmetry by the mouse node. Cell 105, 781-792.