Prediction of lymph node and distant metastasis in patients with endometrial carcinoma: A new model based on demographics, biochemical factors, and tumor histology

Gynecologic Oncology

Volumn 129, Issue 1, 2013, Pages 28-32

  Luomaranta, Anna ^a   Leminen, Arto ^a   Loukovaara, Mikko ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

CA125; Complete blood count; Demographics; Endometrial carcinoma; Lymph node metastasis

Indexed keywords

ADVANCED CANCER; AGED; ANEMIA; AREA UNDER THE CURVE; ARTICLE; BIOCHEMISTRY; CANCER RISK; CANCER STAGING; DEPENDENT VARIABLE; DISTANT METASTASIS; ENDOMETRIUM CARCINOMA; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; LEUKOCYTOSIS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PREDICTION; PREDICTIVE VALUE; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; REGRESSION ANALYSIS; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; THROMBOCYTOSIS;

AGED; AREA UNDER CURVE; BODY MASS INDEX; CA-125 ANTIGEN; DEMOGRAPHY; ENDOMETRIAL NEOPLASMS; ENDOMETRIUM; FEMALE; HUMANS; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS;

EID: 84875443149     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2013.01.008     Document Type: Article

References (49)

1. A. Jemal, F. Bray, M.M. Center, J. Ferlay, E. Ward, and D. Forman Global cancer statistics CA Cancer J Clin 61 2 2011 69 90
2. R. Siegel, D. Naishadham, and A. Jemal Cancer statistics CA Cancer J Clin 62 1 2012 10 29
3. J.I. Sorosky Endometrial cancer Obstet Gynecol 120 2 2012 383 397
4. S.N. Lewin, T.J. Herzog, N.I. Barrena Medel, I. Deutsch, W.M. Burke, and X. Sun Comparative performance of the 2009 International Federation of Gynecology and Obstetrics' staging system for uterine corpus cancer Obstet Gynecol 116 5 2010 1141 1149
5. H.M.J. Werner, J. Trovik, J. Marcickiewicz, S. Tingulstad, A.C. Staff, and F. Amant Revision of FIGO surgical staging in 2009 for endometrial cancer validates to improve risk stratification Gynecol Oncol 125 1 2012 103 108
6. R.C. Boronow, C.P. Morrow, W.T. Creasman, P.J. DiSaia, S.G. Silverberg, and A. Miller Surgical staging in endometrial cancer: clinico-pathologic findings of a prospective study Obstet Gynecol 63 6 1984 825 832
7. W.T. Creasman, C.P. Morrow, B.N. Bundy, H.D. Homesley, J.E. Graham, and P.B. Heller Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group Study Cancer 60 Suppl. 8 1987 2035 2041
8. J.S. Kwon, F. Qiu, R. Saskin, and M.S. Carey Are uterine risk factors more important than nodal status in predicting survival in endometrial cancer? Obstet Gynecol 114 4 2009 736 743
9. N.I. Barrena Medel, T.J. Herzog, I. Deutsch, W.M. Burke, X. Sun, and S.N. Lewin Comparison of the prognostic significance of uterine factors and nodal status for endometrial cancer Am J Obstet Gynecol 204 3 2011 248.e1 248.e7
10. P. Benedetti Panici, S. Basile, F. Maneschi, A. Alberto Lissoni, M. Signorelli, and G. Scambia Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma: randomized clinical trial J Natl Cancer Inst 100 23 2008 1707 1716
11. S.C. Dowdy, B.J. Borah, J.N. Bakkum-Gamez, A.L. Weaver, M.E. McGree, and L.R. Haas Prospective assessment of survival, morbidity, and cost associated with lymphadenectomy in low-risk endometrial cancer Gynecol Oncol 127 1 2012 5 10
12. Y. Todo, H. Kato, M. Kaneuchi, H. Watari, M. Takeda, and N. Sakuragi Survival effect of para-aortic lymphadenectomy in endometrial cancer (SEPAL study): a retrospective cohort analysis Lancet 375 9721 2010 1165 1172
13. T.J. Cade, M.A. Quinn, O.M. McNally, D. Neesham, J. Pyman, and A. Dobrotwir Predictive value of magnetic resonance imaging in assessing myometrial invasion in endometrial cancer: is radiological staging sufficient for planning conservative treatment? Int J Gynecol Cancer 20 7 2010 1166 1169
14. A. Petric, D. Stojanov, V. Lilic, S. Filipovic, P. Bosnjakovic, and R. Zivadinovic The application of magnetic resonance imaging in preoperative evaluation of patients with endometrial carcinoma J Balkan Union Oncol 16 3 2011 492 497
15. M.H. McComiskey, W.G. McCluggage, A. Grey, I. Harley, S. Dobbs, and H.A. Nagar Diagnostic accuracy of magnetic resonance imaging in endometrial cancer Int J Gynecol Cancer 22 6 2012 1020 1025
16. T. Tong, G. Yajia, W. Huaying, and P. Weijun Application of 1.5 T magnetic resonance imaging in endometrial cancer Arch Gynecol Obstet 285 4 2012 1113 1118
17. O. Akbayir, A. Corbacioglu, C. Numanoglu, F.Y. Guleroglu, V. Ulker, and A. Akyol Preoperative assessment of myometrial and cervical invasion in endometrial carcinoma by transvaginal ultrasound Gynecol Oncol 122 3 2011 600 603
18. W. Sawicki, B. Spiewankiewicz, J. Stelmachów, and K. Cendrowski The value of ultrasonography in preoperative assessment of selected prognostic factors in endometrial cancer Eur J Gynaecol Oncol 24 3-4 2003 293 298
19. M. Undurraga, P. Petignat, M.F. Pelte, S. Jacob, J.B. Dubuisson, and P. Loubeyre Magnetic resonance imaging to identify risk of lymph node metastasis in patients with endometrial cancer Int J Gynaecol Obstet 104 3 2009 233 235
20. N.S. Horowitz, F. Dehdashti, T.J. Herzog, J.S. Rader, M.A. Powell, and R.K. Gibb Prospective evaluation of FDG-PET for detecting pelvic and para-aortic lymph node metastasis in uterine corpus cancer Gynecol Oncol 95 3 2004 546 551
21. A. Chao, T.-C. Chang, K.-K. Ng, S. Hsueh, H.-J. Huang, and H.-H. Chou 18F-FDG PET in the management of endometrial cancer Eur J Nucl Med Mol Imaging 33 1 2006 36 44
22. 18F-FDG PET/CT in detecting pelvic and paraaortic lymph node metastasis in patients with endometrial cancer AJR Am J Roentgenol 190 6 2008 1652 1658
23. K. Kitajima, K. Murakami, E. Yamasaki, Y. Kaji, and K. Sugimura Accuracy of integrated FDG-PET/contrast-enhanced CT in detecting pelvic and paraaortic lymph node metastasis in patients with uterine cancer Eur Radiol 19 6 2009 1529 1536
24. M. Signorelli, L. Guerra, A. Buda, M. Picchio, G. Mangili, and T. Dell'Anna Role of integrated FDG PET/CT in the surgical management of patients with high risk early stage endometrial cancer: detection of pelvic nodal metastases Gynecol Oncol 115 2 2009 231 235
25. M. Ballester, G. Dubernard, F. Lécuru, D. Heitz, P. Mathevet, and H. Marret Detection rate and diagnostic accuracy of sentinel-node biopsy in early stage endometrial cancer: a prospective multicentre study (SENTI-ENDO) Lancet Oncol 12 5 2011 469 476
26. F. Khoury-Collado, M.P. Murray, M.L. Hensley, Y. Sonoda, K.M. Alektiar, and D.A. Levine Sentinel lymph node mapping for endometrial cancer improves the detection of metastatic disease to regional lymph nodes Gynecol Oncol 122 2 2011 251 254
27. J. How, S. Lau, J. Press, A. Ferenczy, M. Pelmus, and J. Stern Accuracy of sentinel lymph node detection following intra-operative cervical injection for endometrial cancer: a prospective study Gynecol Oncol 127 2 2012 332 337
28. E. Solima, F. Martinelli, A. Ditto, M. Maccauro, M. Carcangiu, and L. Mariani Diagnostic accuracy of sentinel node in endometrial cancer by using hysteroscopic injection of radiolabeled tracer Gynecol Oncol 126 3 2012 419 423
29. K.M. Alektiar, E. Venkatraman, N. Abu-Rustum, and R.R. Barakat Is endometrial carcinoma intrinsically more aggressive in elderly patients? Cancer 98 11 2003 2368 2377
30. K. Okuma, H. Yamashita, K. Kawana, S. Nakagawa, K. Oda, and K. Nakagawa Advanced age is a significant determinant of poor prognosis in patients treated with surgery plus postoperative radiotherapy for endometrial cancer J Obstet Gynaecol Res 36 4 2010 757 763
31. O.H. Gayar, J.R. Robbins, K. Parikh, M. Lu, T. Buekers, and A. Munkarah Hysterectomy for uterine adenocarcinoma in the elderly: tumor characteristics, and long-term outcome Gynecol Oncol 123 1 2011 71 75
32. S. Vance, R. Yechieli, C. Cogan, R. Hanna, A. Munkarah, and M.A. Elshaikh The prognostic significance of age in surgically staged patients with type II endometrial carcinoma Gynecol Oncol 126 1 2012 16 19
33. E.J. Gates, L. Hirschfield, R.P. Matthews, and O.W. Yap Body mass index as a prognostic factor in endometrioid adenocarcinoma of the endometrium J Natl Med Assoc 98 11 2006 1814 1822
34. O. Akbayir, A. Corbacioglu Esmer, C. Numanoglu, B.P. Cilesiz Goksedef, A. Akca, and L.V. Bakir Influence of body mass index on clinicopathologic features, surgical morbidity and outcome in patients with endometrial cancer Arch Gynecol Obstet 286 5 2012 1269 1276
35. E.J. xCrosbie, C. Roberts, W. Qian, A.M. Swart, H.C. Kitchener, and A.G. Renehan Body mass index does not influence post-treatment survival in early stage endometrial cancer: results from the MRC ASTEC trial Eur J Cancer 48 6 2012 853 864
36. K.F. Tamussino, F. Gücer, O. Reich, F. Moser, E. Petru, and H.S. Scholz Pretreatment hemoglobin, platelet count, and prognosis in endometrial carcinoma Int J Gynecol Cancer 11 3 2001 236 240
37. J. Metindir, and Dilek G. Bilir Preoperative hemoglobin and platelet count and poor prognostic factors in patients with endometrial carcinoma J Cancer Res Clin Oncol 135 1 2009 125 129
38. H. Staszewski Hematological paraneoplastic syndromes Semin Oncol 24 3 1997 329 333
39. M.J. Worley Jr., C.C. Nitschmann, M. Shoni, A.F. Vitonis, J.A. Rauh-Hain, and C.M. Feltmate The significance of preoperative leukocytosis in endometrial carcinoma Gynecol Oncol 125 3 2012 561 565
40. H.H. Chung, J.W. Kim, N.H. Park, Y.S. Song, S.B. Kang, and H.P. Lee Use of preoperative serum CA-125 levels for prediction of lymph node metastasis and prognosis in endometrial cancer Acta Obstet Gynecol Scand 85 12 2006 1501 1505
41. H.S. Kim, C.-Y. Park, J.-M. Lee, J.-K. Lee, C.-H. Cho, and S.-M. Kim Evaluation of serum CA-125 levels for preoperative counseling in endometrioid endometrial cancer: a multi-center study Gynecol Oncol 118 3 2010 283 288
42. Y.L. Chen, C.Y. Huang, T.Y. Chien, S.H. Huang, C.J. Wu, and C.M. Ho Value of pre-operative serum CA125 level for prediction of prognosis in patients with endometrial cancer Aust N Z J Obstet Gynaecol 51 5 2011 397 402
43. A. Yildiz, H. Yetimalar, B. Kasap, C. Aydin, S. Tatar, and F. Soylu Preoperative serum CA 125 level in the prediction of the stage of disease in endometrial carcinoma Eur J Obstet Gynecol Reprod Biol 164 2 2012 191 195
44. R.C. Bast Jr., M. Feeney, H. Lazarus, L.M. Nadler, R.B. Colvin, and R.C. Knapp Reactivity of a monoclonal antibody with human ovarian carcinoma J Clin Invest 68 5 1981 1331 1337
45. V. Kairisto, P. Grönroos, M. Loikkanen, E.-R. Savolainen, K. Punnonen, and M. Syrjälä New Finnish reference limits for the basic blood count Suom Laakaril 58 51-52 2003 5147 5153
46. J.-Y. Lee, D.-C. Jung, S.-H. Park, M.-C. Lim, S.-S. Seo, and S.-Y. Park Preoperative prediction model of lymph node metastasis in endometrial cancer Int J Gynecol Cancer 20 8 2010 1350 1355
47. F. Khoury-Collado, G.E. Glaser, O. Zivanovic, Y. Sonoda, D.A. Levine, and D.S. Chi Improving sentinel lymph node detection rates in endometrial cancer: how many cases are needed? Gynecol Oncol 115 3 2009 453 455
48. S. Kang, H.J. Yoo, J.A. Hwang, M.-C. Lim, S.-S. Seo, and S.-Y. Park Sentinel lymph node biopsy in endometrial cancer: meta-analysis of 26 studies Gynecol Oncol 123 3 2011 522 527
49. S. Nofech-Mozes, N. Ismiil, V. Dubé, R.S. Saad, Z. Ghorab, and A. Grin Interobserver agreement for endometrial cancer characteristics evaluated on biopsy material Obstet Gynecol Int 2012 10.1155/2012/414086 [Article ID 414086]