Role of the integrated FDG PET/CT in the surgical management of patients with high risk clinical early stage endometrial cancer: Detection of pelvic nodal metastases

Gynecologic Oncology

Volumn 115, Issue 2, 2009, Pages 231-235

  Signorelli, Mauro ^a   Guerra, Luca ^a   Buda, Alessandro ^a   Picchio, Maria ^b   Mangili, Giorgia ^b   Dell'Anna, Tiziana ^a   Sironi, Sandro ^a   Messa, Cristina ^a  

^a SAN GERARDO HOSPITAL   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

18F FDG PET CT imaging; Endometrial cancer; High risk; Lymphadenectomy; Nodal metastases

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER INVASION; CANCER PATIENT; CLINICAL ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE SEVERITY; ENDOMETRIUM CANCER; ENDOMETRIUM TUMOR; FEMALE; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; HYSTERECTOMY; IMAGE ANALYSIS; LYMPH NODE METASTASIS; MYOMETRIUM; PATIENT SELECTION; PELVIS LYMPH NODE; PELVIS LYMPHADENECTOMY; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SALPINGOOOPHORECTOMY; SENSITIVITY AND SPECIFICITY; STANDARD;

AGED; ENDOMETRIAL NEOPLASMS; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; PELVIS; POSITRON-EMISSION TOMOGRAPHY; PREOPERATIVE CARE; PROSPECTIVE STUDIES; RADIOPHARMACEUTICALS; SENSITIVITY AND SPECIFICITY;

EID: 70349731442     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2009.07.020     Document Type: Article

References (43)

1. Jemal A., Siegel R., Ward E., et al. Cancer statistics, 2008. CA Cancer J Clin 58 2 (2008 (Mar.-Apr.)) 71-96
2. Keys H.M., Roberts J.A., Brunetto V.L., et al. Gynecologic Oncology Group. A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: a Gynecologic Oncology Group study. Gynecol Oncol 92 3 (2004 (Mar.)) 744-751
3. Creutzberg C.L., van Putten W.L., Koper P.C., et al. Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma. Lancet 355 9213 (2000 (Apr. 22)) 1404-1411
4. Creasman W.T., Kohler M.F., Odicino F., Maisonneuve P., and Boyle P. Prognosis of papillary serous, clear cell, and grade 3 stage I carcinoma of the endometrium. Gynecol Oncol 95 3 (2004 (Dec.)) 593-596
5. Creutzberg C.L., van Putten W.L., Wárlám-Rodenhuis C.C., van den Bergh A.C., de Winter K.A., Koper P.C., et al. Postoperative Radiation Therapy in Endometrial Carcinoma Trial. Outcome of high-risk stage IC, grade 3, compared with stage I endometrial carcinoma patients: the Postoperative Radiation Therapy in Endometrial Carcinoma Trial. J Clin Oncol 22 7 (2004 (Apr. 1)) 1234-1241
6. Announcement. FIGO stages-1988 revision. Gynecol Oncol 35 (1989) 125-127
7. Chan J.K., and Kapp D.S. Role of complete lymphadenectomy in endometrioid uterine cancer. Lancet Oncol 8 9 (2007 (Sep.)) 831-841 (Review)
8. Cragun J.M., Havrilesky L.J., Calingaert B., et al. Retrospective analysis of selective lymphadenectomy in apparent early-stage endometrial cancer. J Clin Oncol 23 16 (2005 (Jun. 1)) 3668-3675
9. Chan J.K., Wu H., Cheung M.K., Shin J.Y., Osann K., and Kapp D.S. The outcomes of 27,063 women with unstaged endometrioid uterine cancer. Gynecol Oncol 106 2 (2007 (Aug.)) 282-288
10. ASTEC study group, Kitchener H., Swart A.M., Qian Q., Amos C., and Parmar M.K. Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study. Lancet 373 9658 (2009 (Jan. 10)) 125-136 Electronic publication 2008 Dec 16
11. Panici P.B., Basile S., Maneschi F., Lissoni A.A., Signorelli M., Scambia G., et al. Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma: randomized clinical trial. J Natl Cancer Inst 100 23 (2008 (Dec. 3)) 1707-1716
12. Girardi F., Petru E., Heydarfadai M., Haas J., and Winter R. Pelvic lymphadenectomy in the surgical treatment of endometrial cancer. Gynecol Oncol 49 (1993) 177-180
13. Larson DM, Johnson KK, Pelvic and para-aortic lymphadenectomy for surgical staging of high-risk end.
14. Boronow R.C., Morrow C.P., Creasman W.T., et al. Surgical staging in endometrial cancer: clinical-pathologic findings in a prospective study. Obstet Gynecol 63 (1984) 825-832
15. Creasman W.T., Morrow C.P., Bundy B.N., Homesley H.D., Graham J.E., and Heller P.B. Surgical pathologic spread patterns of endometrial cancer. Cancer 60 (1987) 2035-2041
16. Ak I., Stokkel M.P., and Pauwels E.K. Positron emission tomography with 2-[18F]fluoro-2-deoxy-D glucose in oncology. Part II. The clinical value in detecting and staging primary tumours. J Cancer Res Clin Oncol 126 10 (2000) 560-574
17. Cermik T.F., Mavi A., Basu S., and Alavi A. Impact of FDG PET on the preoperative staging of newly diagnosed breast cancer. Eur J Nucl Med Mol Imaging 35 3 (2008 (Mar)) 475-483
18. Suzuki R., Miyagi E., Takahashi N., et al. Validity of positron emission tomography using fluoro-2-deoxyglucose for the preoperative evaluation of endometrial cancer. Int. J. Gynecol. Cancer 17 4 (2007) 890-896
19. Horowitz N.S., Dehdashti F., Herzog T.J., et al. Prospective evaluation of FDG-PET for detecting pelvic and para-aortic lymph node metastasis in uterine corpus cancer. Gynecol Oncol 95 3 (2004) 546-551
20. Chao A., Chang T.C., Ng K.K., et al. 18F-FDG PET in the management of endometrial cancer. Eur J Nucl Med Mol Imaging 33 1 (2006) 36-44
21. Messa C., Bettinardi V., Picchio M., et al. PET/CT in diagnostic oncology. Q J Nucl Med Mol Imaging 48 2 (2004) 66-75
22. Park J.Y., Kim E.N., Kim D.Y., et al. Comparison of the validity of magnetic resonance imaging and positron emission tomography/computed tomography in the preoperative evaluation of patients with uterine corpus cancer. Gynecol Oncol 108 (2008) 486-492
23. Kitajima K., Murakami K., Yamasaki E., et al. Accuracy of 18F-FDG PET/CT in detecting pelvic and paraaortic lymph node metastasis in patients with endometrial cancer. AJR 190 (2008) 1652-1658
24. Nayot D., Kwon J.S., Carey M.S., et al. Does preoperative positron emission tomography with computed tomography predict nodal status in endometrial cancer? A pilot study. Current Oncology 15 (2008) 123-125
25. McMeekin D.S., Lashbrook D., Gold M., et al. Nodal distribution and its significance in FIGO stage IIIc endometrial cancer. Gynecol Oncol 82 (2001) 375-379
26. Reich O., Winter R., Pickel H., et al. Does the size of pelvic lymph nodes predict metastatic involvement in patients with endometrial cancer?. Int J Gynecol Cancer 6 (1996) 445-447
27. Hricak H., Rubinstein L.V., Gherman G.M., et al. MR imaging evaluation of endometrial cancer: results of an NCI cooperative study. Radiology 179 (1991) 829-832
28. Sugiyama T., Nishida T., Ushijima K., et al. Detection of lymph node metastasis in ovarian carcinoma and uterine corpus carcinoma by preoperative computerized tomography or magnetic resonance imaging. J Obstet Gynaecol 21 (1995) 551-556
29. Connor J.P., Andrews J.I., Anderson B., and Buller R.E. Computed tomography in endometrial cancer. Obstet Gynecol 95 (2000) 692-696
30. Manfredi R., Mirk P., Maresca G., et al. Local-regional staging of endometrial carcinoma: role of MR imaging in surgical planning. Radiology 231 (2004) 372-378
31. Rockall A.G., Sohaib S.A., Harisinghani M.G., et al. Diagnostic performance of nanoparticle-enhanced magnetic resonance imaging in the diagnosis of lymph node metastases in patients with endometrial and cervical cancer. J Clin Oncol 23 (2005) 2813-2821
32. Rockall A.G., Meroni R., Sohaib S.A., et al. Evaluation of endometrial carcinoma on magnetic resonance imaging. Int J Gynecol Cancer 17 (2007) 188-196
33. Ayhan A., Celik H., and Dursun P. Lymphatic mapping and sentinel node biopsy in gynecological cancers: a critical review of the literature. World J Surg Oncol 6 (2008 (May 20)) 53 (Review)
34. Van der Zee A.G., Oonk M.H., De Hullu J.A., Ansink A.C., Vergote I., Verheijen R.H., et al. Sentinel node dissection is safe in the treatment of early-stage vulvar cancer. J Clin Oncol 26 6 (2008 (Feb. 20)) 884-889
35. Altgassen C., Hertel H., Brandstädt A., Köhler C., Dürst M., and Schneider A. AGO Study Group Multicenter validation study of the sentinel lymph node concept in cervical cancer: AGO Study Group. J Clin Oncol 26 18 (2008 (Jun. 20)) 2943-2951
36. Ballester M., Dubernard G., Rouzier R., Barranger E., and Darai E. Use of the sentinel node procedure to stage endometrial cancer. Ann Surg Oncol 15 5 (2008 (May)) 1523-1529
37. Delpech Y., Cortez A., Coutant C., Callard P., Uzan S., Darai E., et al. The sentinel node concept in endometrial cancer: histopathologic validation by serial section and immunohistochemistry. Ann Oncol 18 11 (2007 (Nov.)) 1799-1803
38. Perrone A.M., Casadio P., Formelli G., Levorato M., Ghi T., Costa S., et al. Cervical and hysteroscopic injection for identification of sentinel lymph node in endometrial cancer. Gynecol Oncol 111 1 (2008 (Oct.)) 62-67
39. Clement D., Bats A.S., Ghazzar-Pierquet N., La Frere Belda M.A., Larousserie F., and Lecuru F. Sentinel lymph nodes in endometrial cancer: is hysteroscopic injection valid?. Eur J Gynaecol Oncol 29 3 (2008) 239-244
40. Frumovitz M., Bodurka D.C., Broaddus R.R., Coleman R.L., Sood A.K., Gershenson D.M., et al. Lymphatic mapping and sentinel node biopsy in women with high-risk endometrial cancer. Gynecol Oncol 104 1 (2007 (Jan.)) 100-103
41. Selman T.J., Mann C.H., Zamora J., and Khan K.S. A systematic review of tests for lymph node status in primary endometrial cancer. BMC Womens Health 8 (2008 (May 5)) 8 (Review)
42. de Hullu J.A., Oonk M.H.M., Ansink A.C., Hollema H., Jager P.L., and van der Zee A.G.J. Pitfalls in the sentinel lymph node procedure in vulvar cancer. Gynecol Oncol 94 1 (2004 (Jul.)) 10-15
43. Boronow R.C. Endometrial cancer and lymph node surgery: the spins continue-a case for reason. Gynecol Oncol 111 1 (2008 (Oct)) 3-6