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Volumn 76, Issue 3, 2013, Pages 346-353

Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum

Author keywords

[No Author keywords available]

Indexed keywords

ACYLGLYCEROL; ANTIINFECTIVE AGENT; ARZANOL; BENZOFURAN DERIVATIVE; COUMARIC ACID; HELICHRYSUM EXTRACT; HETERODIMER; PHENOL DERIVATIVE; PHLOROGLUCINOL DERIVATIVE; PYRONE DERIVATIVE; SANTINOL A1; SANTINOL A2; SANTINOL A3; SANTINOL B; SANTINOL C; SANTINOL D; UNCLASSIFIED DRUG;

EID: 84875441915     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np3007149     Document Type: Article
Times cited : (52)

References (32)
  • 12
    • 84875450651 scopus 로고    scopus 로고
    • Leonardo Santini (1904-1983), an Italian physician, carried out the first systematic studies on the clinical anti-inflammatory properties of H. italicum
    • Leonardo Santini (1904-1983), an Italian physician, carried out the first systematic studies on the clinical anti-inflammatory properties of H. italicum
  • 13
    • 34248995430 scopus 로고
    • Santini summarized the results of almost two decades of clinical observation on H. italicum in a review article that appeared in 1952.(1) On the basis of these studies, extracts of various Helichrysum species were introduced to the Italian pharmaceutical market for the treatment of cough. The quality and origin of these extracts were questioned by L. Santini (personal communication of his son, Maurizio Santini, to G.A.), and they were eventually removed from the pharmaceutical market in the 1970s. H. italicum shows a remarkable infraspecific variation in its phytochemical profile, even without its various subspecies,(7) and we have found that several commercial samples of the plant are totally devoid of pyrone derivatives. It is therefore unsurprising that, in the lack of a proper standardization, the early Helichyrsum pharmaceutical products were doomed to failure
    • Santini, L. Atti Soc. Lomb. Sci. Med. Biol. 1949, 5, 18). Santini summarized the results of almost two decades of clinical observation on H. italicum in a review article that appeared in 1952.(1) On the basis of these studies, extracts of various Helichrysum species were introduced to the Italian pharmaceutical market for the treatment of cough. The quality and origin of these extracts were questioned by L. Santini (personal communication of his son, Maurizio Santini, to G.A.), and they were eventually removed from the pharmaceutical market in the 1970s. H. italicum shows a remarkable infraspecific variation in its phytochemical profile, even without its various subspecies,(7) and we have found that several commercial samples of the plant are totally devoid of pyrone derivatives. It is therefore unsurprising that, in the lack of a proper standardization, the early Helichyrsum pharmaceutical products were doomed to failure
    • (1949) Atti Soc. Lomb. Sci. Med. Biol. , vol.5 , pp. 18
    • Santini, L.1
  • 22
    • 0036201069 scopus 로고    scopus 로고
    • exemplify phloroglucinyl heterodimers showing, respectively, two distinct sets of signals or very broad spectra in their NMR spectra at room temperature
    • Appendino, G.; Bianchi, F.; Minassi, A.; Sterner, O.; Ballero, M.; Gibbons, S. J. Nat. Prod. 2002, 65, 334-338) exemplify phloroglucinyl heterodimers showing, respectively, two distinct sets of signals or very broad spectra in their NMR spectra at room temperature
    • (2002) J. Nat. Prod. , vol.65 , pp. 334-338
    • Appendino, G.1    Bianchi, F.2    Minassi, A.3    Sterner, O.4    Ballero, M.5    Gibbons, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.