Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization

Development (Cambridge)

Volumn 140, Issue 8, 2013, Pages 1785-1795

  Sipe, Conor W ^a   Liu, Lixia ^a,b   Lee, Jianyi ^a   Grimsley Myers, Cynthia ^a,c   Lu, Xiaowei ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Deafness; Dynein; Lis1; Microtubule; Nectin; Pafah1b1; PCP; Rac GTPase; Stereociliary bundle

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; LIS1 PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE PROTEIN; NECTIN 1; P21 ACTIVATED KINASE; RAC PROTEIN; TIAM1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL POLARITY; CELL STRUCTURE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GOLGI COMPLEX; HAIR CELL; MEDIATOR; MICROTUBULE; MICROTUBULE ASSEMBLY; MICROTUBULE ORGANIZING CENTER; MITOCHONDRION; MOUSE; NEUROEPITHELIUM; NONHUMAN; PLANAR CELL POLARITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ANIMALS; BLOTTING, WESTERN; CELL POLARITY; DNA PRIMERS; GENE DELETION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HAIR CELLS, AUDITORY; IMMUNOHISTOCHEMISTRY; MICE; MICROSCOPY, ELECTRON, SCANNING; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; ORGAN OF CORTI; ORGANELLES; SIGNAL TRANSDUCTION;

EID: 84875435850     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.089763     Document Type: Article

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