In-vitro Validation of Cytokine Neutralizing Antibodies by Testing with Ovine Mononuclear Splenocytes

Journal of Comparative Pathology

Volumn 148, Issue 2-3, 2013, Pages 252-258

  Chen, X ^a   Threlkeld, S W ^a   Cummings, E E ^a   Sadowska, G B ^a   Lim, Y P ^a,b   Padbury, J F ^a   Sharma, S ^a   Stonestreet, B S ^a  

^a BROWN UNIVERSITY   (United States)

^b ProThera Biologics Inc   (United States)

Author keywords

Monoclonal antibody; Mononuclear cells; Pro inflammatory cytokines; Sheep

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA ANTIBODY; INTERLEUKIN 6 ANTIBODY; NEUTRALIZING ANTIBODY; STAT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DENSITOMETRY; FEMALE; IN VITRO STUDY; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEEP; SIGNAL TRANSDUCTION; SPLEEN CELL; VALIDATION STUDY; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, NEUTRALIZING; CELLS, CULTURED; CYTOKINES; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; MODELS, ANIMAL; NF-KAPPA B; SHEEP; SHEEP DISEASES; SPLEEN; STAT3 TRANSCRIPTION FACTOR;

OVIS; OVIS ARIES;

EID: 84875387019     PISSN: 00219975     EISSN: 15323129     Source Type: Journal    
DOI: 10.1016/j.jcpa.2012.06.001     Document Type: Article

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