Structural characterization of recombinant alpha-1-antitrypsin expressed in a human cell line

Analytical Biochemistry

Volumn 437, Issue 1, 2013, Pages 20-28

  Wang, Zihao ^a   Hilder, Thomas L ^a   Van Der Drift, Koen ^a   Sloan, Jessica ^a   Wee, Kevin ^a  

^a Department of BioAnalytics   (United States)

Author keywords

Alpha 1 antitrypsin; Glycosylation; Liquid chromatography; Mass spectrometry; Recombinant; Sialylation

Indexed keywords

CELL CULTURE; GLYCOSYLATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PULMONARY DISEASES;

ANTITRYPSIN; BIOCHEMICAL TECHNIQUES; CHRONIC OBSTRUCTIVE PULMONARY DISEASE; N-LINKED GLYCOSYLATION; RECOMBINANT; SECONDARY AND TERTIARY STRUCTURES; SIALYLATION; STRUCTURAL CHARACTERIZATION;

POLYSACCHARIDES;

ALPHA 1 ANTITRYPSIN; ASIALOGLYCOPROTEIN RECEPTOR; GALACTOSE; GLYCAN; RECOMBINANT PROTEIN; SIALIC ACID DERIVATIVE;

ARTICLE; CIRCULAR DICHROISM; FUCOSYLATION; GEL ELECTROPHORESIS; GLYCOSYLATION; HUMAN; HUMAN CELL; HYDROLYSIS; ISOELECTRIC FOCUSING; ISOELECTRIC POINT; LINKAGE ANALYSIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN STRUCTURE; RETINA CELL; SIALYLATION; STRUCTURE ANALYSIS; TERMINAL SEQUENCE;

EID: 84875384860     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.02.006     Document Type: Article

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