Antihyperalgesic and antiallodynic effect of sirolimus in rat model of adjuvant arthritis

European Journal of Pharmacology

Volumn 705, Issue 1-3, 2013, Pages 35-41

  Orhan, Cahide Elif ^a,b   Önal, Aytül ^a   UyanIkgil, Yiǧit ^a   Ülker, Sibel ^a  

^a EGE UNIVERSITY   (Turkey)

^b Department of R and D   (Turkey)

Author keywords

(Rat); Adjuvant arthritis; Inflammatory cytokine; Rheumatoid arthritis; Sirolimus

Indexed keywords

ALCOHOL; FREUND ADJUVANT; INTERLEUKIN 1BETA; INTERLEUKIN 6; RAPAMYCIN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ADJUVANT ARTHRITIS; ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRALGIA; ARTICLE; CARTILAGE DEGENERATION; CELL INFILTRATION; CONTROLLED STUDY; DISEASE MODEL; DRUG BLOOD LEVEL; DRUG HALF LIFE; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPERALGESIA; INFLAMMATORY CELL; INOCULATION; LOCOMOTION; LUMBAR SPINAL CORD; MALE; METACARPOPHALANGEAL JOINT; MICROSCOPY; NONHUMAN; OSTEOLYSIS; PAW EDEMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RHEUMATOID ARTHRITIS; SYNOVIUM; TREATMENT OUTCOME; WESTERN BLOTTING;

ANALGESICS; ANIMALS; ARTHRITIS, EXPERIMENTAL; BEHAVIOR, ANIMAL; CYTOKINES; HYPERALGESIA; IMMUNOSUPPRESSIVE AGENTS; MALE; MOTOR ACTIVITY; RATS; RATS, WISTAR; SIROLIMUS; SPINAL CORD;

EID: 84875359614     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.02.013     Document Type: Article

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