-
1
-
-
0038724909
-
C-Met: Structure, functions and potential for therapeutic inhibition
-
12884908 10.1023/A:1023768811842 1:CAS:528:DC%2BD3sXjslyiurY%3D
-
Ma PC, Maulik G, Christensen J, Salgia R. c-Met: structure, functions and potential for therapeutic inhibition. Cancer Metastasis Rev. 2003;22:309-25.
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 309-325
-
-
Ma, P.C.1
Maulik, G.2
Christensen, J.3
Salgia, R.4
-
2
-
-
10744228765
-
A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo
-
14612533 1:CAS:528:DC%2BD3sXovVGltL4%3D
-
Christensen JG, Schreck R, Burrows J, et al. A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo. Cancer Res. 2003;63:7345-55.
-
(2003)
Cancer Res
, vol.63
, pp. 7345-7355
-
-
Christensen, J.G.1
Schreck, R.2
Burrows, J.3
-
3
-
-
10744231064
-
Both hepatocyte growth factor (HGF) and stromal-derived factor-1 regulate the metastatic behavior of human rhabdomyosarcoma cells, but only HGF enhances their resistance to radiochemotherapy
-
14633723 1:CAS:528:DC%2BD3sXptFOltLw%3D
-
Jankowski K, Kucia M, Wysoczynski M, et al. Both hepatocyte growth factor (HGF) and stromal-derived factor-1 regulate the metastatic behavior of human rhabdomyosarcoma cells, but only HGF enhances their resistance to radiochemotherapy. Cancer Res. 2003;63:7926-35.
-
(2003)
Cancer Res
, vol.63
, pp. 7926-7935
-
-
Jankowski, K.1
Kucia, M.2
Wysoczynski, M.3
-
4
-
-
0141988690
-
C-Met mutational analysis in small cell lung cancer: Novel juxtamembrane domain mutations regulating cytoskeletal functions
-
14559814 1:CAS:528:DC%2BD3sXotV2ju74%3D
-
Ma PC, Kijima T, Maulik G, et al. c-Met mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions. Cancer Res. 2003;63:6272-8.
-
(2003)
Cancer Res
, vol.63
, pp. 6272-6278
-
-
Ma, P.C.1
Kijima, T.2
Maulik, G.3
-
5
-
-
34248575532
-
A selective small molecule inhibitor of c-Met, PHA66 inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts
-
17440059 10.1158/0008-5472.CAN-06-4416 1:CAS:528:DC%2BD2sXkt1KjtbY%3D
-
Puri N, Khramtsov A, Ahmed S, et al. A selective small molecule inhibitor of c-Met, PHA66 inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts. Cancer Res. 2007;67:3529-34.
-
(2007)
Cancer Res
, vol.67
, pp. 3529-3534
-
-
Puri, N.1
Khramtsov, A.2
Ahmed, S.3
-
6
-
-
0028268338
-
Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity
-
8134112 1:CAS:528:DyaK2cXis1Ojtr8%3D
-
Bellusci S, Moens G, Gaudino G, et al. Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity. Oncogene. 1994;9:1091-9.
-
(1994)
Oncogene
, vol.9
, pp. 1091-1099
-
-
Bellusci, S.1
Moens, G.2
Gaudino, G.3
-
7
-
-
0029774380
-
Autocrine hepatocyte growth factor/scatter factor-Met signaling induces transformation and the invasive/metastatic phenotype in C127 cells
-
8761307 1:CAS:528:DyaK28Xlt1yitbs%3D
-
Jeffers M, Rong S, Anver M, Vande Woude GF. Autocrine hepatocyte growth factor/scatter factor-Met signaling induces transformation and the invasive/metastatic phenotype in C127 cells. Oncogene. 1996;13:853-6.
-
(1996)
Oncogene
, vol.13
, pp. 853-856
-
-
Jeffers, M.1
Rong, S.2
Anver, M.3
Vande Woude, G.F.4
-
8
-
-
0031037754
-
Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor
-
9012848 10.1073/pnas.94.2.701 1:CAS:528:DyaK2sXnvVCntQ%3D%3D
-
Takayama H, LaRochelle WJ, Sharp R, et al. Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor. Proc Natl Acad Sci USA. 1997;94:701-6.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 701-706
-
-
Takayama, H.1
Larochelle, W.J.2
Sharp, R.3
-
9
-
-
0346122895
-
Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways
-
14627990 10.1038/sj.onc.1207063 1:CAS:528:DC%2BD3sXptVOrtLo%3D
-
Gallego MI, Bierie B, Hennighausen L. Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways. Oncogene. 2003;22:8498-508.
-
(2003)
Oncogene
, vol.22
, pp. 8498-8508
-
-
Gallego, M.I.1
Bierie, B.2
Hennighausen, L.3
-
10
-
-
19544389146
-
C-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention
-
15922853 10.1016/j.canlet.2004.09.044 1:CAS:528:DC%2BD2MXks1Ggs7c%3D
-
Christensen JG, Burrows J, Salgia R. c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention. Cancer Lett. 2005;225:1-26.
-
(2005)
Cancer Lett
, vol.225
, pp. 1-26
-
-
Christensen, J.G.1
Burrows, J.2
Salgia, R.3
-
11
-
-
0141481285
-
A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase
-
14500382 1:CAS:528:DC%2BD3sXntleku7s%3D
-
Sattler M, Pride YB, Ma P, et al. A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase. Cancer Res. 2003;63:5462-9.
-
(2003)
Cancer Res
, vol.63
, pp. 5462-5469
-
-
Sattler, M.1
Pride, Y.B.2
Ma, P.3
-
12
-
-
0036217531
-
Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis
-
11956815 10.1007/s00428-001-0570-0 1:CAS:528:DC%2BD38Xks1GmsLg%3D
-
Hao X, Frayling IM, Willcocks TC, Han W, Tomlinson IP, Pignatelli MN, Pretlow TP, Talbot IC. Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis. Virchows Arch. 2002;440:362-6.
-
(2002)
Virchows Arch
, vol.440
, pp. 362-366
-
-
Hao, X.1
Frayling, I.M.2
Willcocks, T.C.3
Han, W.4
Tomlinson, I.P.5
Pignatelli, M.N.6
Pretlow, T.P.7
Talbot, I.C.8
-
13
-
-
0030800317
-
Reduced expression of molecules of the cadherin/catenin complex in the transition from colorectal adenoma to carcinoma
-
9216695 1:CAS:528:DyaK2sXkvFylsbg%3D
-
Hao X, Palazzo JP, Ilyas M, Tomlinson I, Talbot IC. Reduced expression of molecules of the cadherin/catenin complex in the transition from colorectal adenoma to carcinoma. Anticancer Res. 1997;17:2241-7.
-
(1997)
Anticancer Res
, vol.17
, pp. 2241-2247
-
-
Hao, X.1
Palazzo, J.P.2
Ilyas, M.3
Tomlinson, I.4
Talbot, I.C.5
-
14
-
-
1342321786
-
Lessons learned from the development of imatinib
-
15036939 10.1016/j.leukres.2003.10.002 1:CAS:528:DC%2BD2cXhsVOgur0%3D
-
Lydon NB, Druker BJ. Lessons learned from the development of imatinib. Leuk Res. 2004;28(Suppl 1):S29-38.
-
(2004)
Leuk Res
, vol.28
, Issue.SUPPL. 1
-
-
Lydon, N.B.1
Druker, B.J.2
-
15
-
-
79955420135
-
Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer
-
21464397 10.1093/jnci/djr093
-
De Bacco F, Luraghi P, Medico E, et al. Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer. J Natl Cancer Inst. 2011;103:645-61.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 645-661
-
-
De Bacco, F.1
Luraghi, P.2
Medico, E.3
-
16
-
-
84856152266
-
Targeting MET in cancer: Rationale and progress
-
22270953 10.1038/nrc3205 1:CAS:528:DC%2BC38XhtFSmu7s%3D
-
Gherardi E, Birchmeier W, Birchmeier C, et al. Targeting MET in cancer: rationale and progress. Nat Rev Cancer. 2012;12:89-103.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 89-103
-
-
Gherardi, E.1
Birchmeier, W.2
Birchmeier, C.3
-
17
-
-
0035159240
-
MET receptor is overexpressed but not mutated in oral squamous cell carcinomas
-
11748586 10.1002/jcp.10010 1:CAS:528:DC%2BD3MXotFGqsbc%3D
-
Morello S, Olivero M, Aimetti M, et al. MET receptor is overexpressed but not mutated in oral squamous cell carcinomas. J Cell Physiol. 2001;189:285-90.
-
(2001)
J Cell Physiol
, vol.189
, pp. 285-290
-
-
Morello, S.1
Olivero, M.2
Aimetti, M.3
-
18
-
-
0033945893
-
Staging of head and neck squamous cell carcinoma using the MET oncogene product as marker of tumor cells in lymph node metastases
-
10861506 10.1002/1097-0215(20000520)89:3<286: AID-IJC12>3.0.CO;2-U 1:STN:280:DC%2BD3czitFCitQ%3D%3D
-
Cortesina G, Martone T, Galeazzi E, et al. Staging of head and neck squamous cell carcinoma using the MET oncogene product as marker of tumor cells in lymph node metastases. Int J Cancer. 2000;89:286-92.
-
(2000)
Int J Cancer
, vol.89
, pp. 286-292
-
-
Cortesina, G.1
Martone, T.2
Galeazzi, E.3
-
19
-
-
0035175805
-
Profiling of differentially expressed cancer-related genes in esophageal squamous cell carcinoma (ESCC) using human cancer cDNA arrays: Overexpression of oncogene MET correlates with tumor differentiation in ESCC
-
11705871 1:CAS:528:DC%2BD3MXptFais7Y%3D
-
Hu YC, Lam KY, Law S, Wong J, Srivastava G. Profiling of differentially expressed cancer-related genes in esophageal squamous cell carcinoma (ESCC) using human cancer cDNA arrays: overexpression of oncogene MET correlates with tumor differentiation in ESCC. Clin Cancer Res. 2001;7:3519-25.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3519-3525
-
-
Hu, Y.C.1
Lam, K.Y.2
Law, S.3
Wong, J.4
Srivastava, G.5
-
20
-
-
1642535487
-
The hepatocyte growth factor regulatory factors in human breast cancer
-
14734471 10.1158/1078-0432.CCR-0553-3 1:CAS:528:DC%2BD2cXkvF2mtg%3D%3D
-
Parr C, Watkins G, Mansel RE, Jiang WG. The hepatocyte growth factor regulatory factors in human breast cancer. Clin Cancer Res. 2004;10:202-11.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 202-211
-
-
Parr, C.1
Watkins, G.2
Mansel, R.E.3
Jiang, W.G.4
-
21
-
-
0032246495
-
Overexpression of c-Met/hepatocyte growth factor receptors in human prostatic adenocarcinoma
-
9876767 1:CAS:528:DyaK1MXkt1Slug%3D%3D
-
Inoue K, Chikazawa M, Karashima T, et al. Overexpression of c-Met/hepatocyte growth factor receptors in human prostatic adenocarcinoma. Acta Med Okayama. 1998;52:305-10.
-
(1998)
Acta Med Okayama
, vol.52
, pp. 305-310
-
-
Inoue, K.1
Chikazawa, M.2
Karashima, T.3
-
22
-
-
0032946931
-
Hepatocyte growth factor/scatter factor, its molecular, cellular and clinical implications in cancer
-
10226727 10.1016/S1040-8428(98)00019-5 1:STN:280:DyaK1M3ktleitg%3D%3D
-
Jiang W, Hiscox S, Matsumoto K, Nakamura T. Hepatocyte growth factor/scatter factor, its molecular, cellular and clinical implications in cancer. Crit Rev Oncol Hematol. 1999;29:209-48.
-
(1999)
Crit Rev Oncol Hematol
, vol.29
, pp. 209-248
-
-
Jiang, W.1
Hiscox, S.2
Matsumoto, K.3
Nakamura, T.4
-
23
-
-
0035573938
-
Hepatocyte growth factor expression in human cancer and therapy with specific inhibitors
-
11908677 1:CAS:528:DC%2BD38Xis1amtL4%3D
-
Haddad R, Lipson KE, Webb CP. Hepatocyte growth factor expression in human cancer and therapy with specific inhibitors. Anticancer Res. 2001;21:4243-52.
-
(2001)
Anticancer Res
, vol.21
, pp. 4243-4252
-
-
Haddad, R.1
Lipson, K.E.2
Webb, C.P.3
-
24
-
-
0035041119
-
Receptor tyrosine kinases as therapeutic targets: The model of the MET oncogene
-
11465538 10.2174/1389450013348920 1:CAS:528:DC%2BD3MXisVCqsrw%3D
-
Longati P, Comoglio PM, Bardelli A. Receptor tyrosine kinases as therapeutic targets: the model of the MET oncogene. Curr Drug Targets. 2001;2:41-55.
-
(2001)
Curr Drug Targets
, vol.2
, pp. 41-55
-
-
Longati, P.1
Comoglio, P.M.2
Bardelli, A.3
-
25
-
-
5144226615
-
A selective c-met inhibitor blocks an autocrine hepatocyte growth factor loop in ANBL-6 cells and prevents migration and adhesion of myeloma cells
-
15475459 10.1158/1078-0432.CCR-04-0874 1:CAS:528:DC%2BD2cXot1Ohsr8%3D
-
Hov H, Holt RU, Ro TB, et al. A selective c-met inhibitor blocks an autocrine hepatocyte growth factor loop in ANBL-6 cells and prevents migration and adhesion of myeloma cells. Clin Cancer Res. 2004;10:6686-94.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6686-6694
-
-
Hov, H.1
Holt, R.U.2
Ro, T.B.3
-
26
-
-
50249160548
-
Small molecule c-Met inhibitor PHA-665752: Effect on cell growth and motility in papillary thyroid carcinoma
-
18327775 10.1002/hed.20816
-
Chattopadhyay C, El-Naggar AK, Williams MD, Clayman GL. Small molecule c-Met inhibitor PHA-665752: effect on cell growth and motility in papillary thyroid carcinoma. Head Neck. 2008;30:991-1000.
-
(2008)
Head Neck
, vol.30
, pp. 991-1000
-
-
Chattopadhyay, C.1
El-Naggar, A.K.2
Williams, M.D.3
Clayman, G.L.4
-
27
-
-
33750709237
-
Inhibition of c-Met as a therapeutic strategy for esophageal adenocarcinoma
-
17132227 10.1593/neo.06499 1:CAS:528:DC%2BD28Xht1eitrfF
-
Watson GA, Zhang X, Stang MT, et al. Inhibition of c-Met as a therapeutic strategy for esophageal adenocarcinoma. Neoplasia. 2006;8:949-55.
-
(2006)
Neoplasia
, vol.8
, pp. 949-955
-
-
Watson, G.A.1
Zhang, X.2
Stang, M.T.3
-
28
-
-
33144462553
-
Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752
-
16461907 10.1073/pnas.0508776103 1:CAS:528:DC%2BD28XhslGjtrg%3D
-
Smolen GA, Sordella R, Muir B, et al. Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752. Proc Natl Acad Sci USA. 2006;103:2316-21.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2316-2321
-
-
Smolen, G.A.1
Sordella, R.2
Muir, B.3
|