Copy-number variation of cancer-gene orthologs is sufficient to induce cancer-like symptoms in Saccharomyces cerevisiae

BMC Biology

Volumn 11, Issue , 2013, Pages

  de Clare, Michaela ^a   Oliver, Stephen G ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Cancer; Copy number variation; Haploinsufficiency; Model organism; Yeast

Indexed keywords

EUKARYOTA; MAMMALIA; SACCHAROMYCES CEREVISIAE;

ANTINEOPLASTIC AGENT;

APOPTOSIS; ARTICLE; CELL CYCLE; COPY NUMBER VARIATION; CYTOLOGY; DRUG EFFECT; FUNGAL GENE; GENE DELETION; GENETICS; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MOLECULAR GENETICS; NEOPLASM; PHENOTYPE; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; TUMOR GENE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; DNA COPY NUMBER VARIATIONS; GENE DELETION; GENES, FUNGAL; GENES, NEOPLASM; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MOLECULAR SEQUENCE ANNOTATION; NEOPLASMS; PHENOTYPE; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 84875327665     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-11-24     Document Type: Article

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