Dose-dependent pulmonary response of well-dispersed titanium dioxide nanoparticles following intratracheal instillation

Journal of Nanoparticle Research

Volumn 15, Issue 4, 2013, Pages

  Oyabu, Takako ^a   Morimoto, Yasuo ^a   Hirohashi, Masami ^a   Horie, Masanori ^a   Kambara, Tatsunori ^a   Lee, Byeong Woo ^a   Hashiba, Masayoshi ^a   Mizuguchi, Yohei ^a   Myojo, Toshihiko ^a   Kuroda, Etsushi ^b  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Clearance; Inflammation; Intratracheal instillation; Titanium dioxide

Indexed keywords

BIOLOGICAL ORGANS; NANOPARTICLES; OXIDE MINERALS; PATHOLOGY; TITANIUM DIOXIDE;

ALVEOLAR SPACES; BRONCHOALVEOLAR LAVAGE FLUID; CLEARANCE; GRANULOMATOUS LESIONS; INFLAMMATION; INTRATRACHEAL INSTILLATION; LOCAL ACCUMULATIONS; NEUTROPHIL INFILTRATION;

TIO2 NANOPARTICLES;

CINC 1 PROTEIN; NANOPARTICLE; PROTEIN; TITANIUM DIOXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHIOLE; CONTROLLED STUDY; DISPERSION; DOSE RESPONSE; HISTOPATHOLOGY; INSTILLATION SITE IRRITATION; LUNG ALVEOLUS; LUNG LAVAGE; LUNG PARENCHYMA; MALE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; PARTICLE CLEARANCE; PARTICLE SIZE; PHYSICAL PARAMETERS; PNEUMONIA; PRIORITY JOURNAL; RAT;

EID: 84875324417     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-013-1600-y     Document Type: Article

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