메뉴 건너뛰기




Volumn 6, Issue , 2013, Pages 189-200

Considerations in selecting rapid-onset opioids for the management of breakthrough pain

Author keywords

Breakthrough pain; Fentanyl; Pain; Rapid onset opioid

Indexed keywords

FENTANYL; FENTANYL CITRATE; MORPHINE; MORPHINE SULFATE; OXYCODONE; PLACEBO;

EID: 84875322032     PISSN: 11787090     EISSN: None     Source Type: Journal    
DOI: 10.2147/JPR.S40745     Document Type: Review
Times cited : (35)

References (81)
  • 1
    • 2942637938 scopus 로고    scopus 로고
    • Breakthrough pain characteristics and syndromes in patients with cancer pain. An international survey
    • Caraceni A, Martini C, Zecca E, et al. Breakthrough pain characteristics and syndromes in patients with cancer pain. An international survey. Palliat Med. 2004;18:177-183.
    • (2004) Palliat Med , vol.18 , pp. 177-183
    • Caraceni, A.1    Martini, C.2    Zecca, E.3
  • 2
    • 0025336568 scopus 로고
    • Breakthrough pain: Definition, prevalence and characteristics
    • Portenoy RK, Hagen NA. Breakthrough pain: definition, prevalence and characteristics. Pain. 1990;41:273-281.
    • (1990) Pain , vol.41 , pp. 273-281
    • Portenoy, R.K.1    Hagen, N.A.2
  • 3
    • 33746559173 scopus 로고    scopus 로고
    • Prevalence and characteristics of breakthrough pain in opioid-treated patients with chronic noncancer pain
    • Portenoy RK, Bennett DS, Rauck R, et al. Prevalence and characteristics of breakthrough pain in opioid-treated patients with chronic noncancer pain. J Pain. 2006;7:583-591.
    • (2006) J Pain , vol.7 , pp. 583-591
    • Portenoy, R.K.1    Bennett, D.S.2    Rauck, R.3
  • 4
    • 77952336590 scopus 로고    scopus 로고
    • Breakthrough pain in community-dwelling patients with cancer pain and noncancer pain, part 1: Prevalence and characteristics
    • Portenoy RK, Bruns D, Shoemaker B, Shoemaker SA. Breakthrough pain in community-dwelling patients with cancer pain and noncancer pain, part 1: prevalence and characteristics. J Opioid Manag. 2010;6:97-108.
    • (2010) J Opioid Manag , vol.6 , pp. 97-108
    • Portenoy, R.K.1    Bruns, D.2    Shoemaker, B.3    Shoemaker, S.A.4
  • 5
    • 70449512784 scopus 로고    scopus 로고
    • Novel formulations and routes of administration for opioids in the treatment of breakthrough pain
    • Christrup LL, Lundorff L, Werner M. Novel formulations and routes of administration for opioids in the treatment of breakthrough pain. Therapy. 2009;6:695-706.
    • (2009) Therapy , vol.6 , pp. 695-706
    • Christrup, L.L.1    Lundorff, L.2    Werner, M.3
  • 7
    • 79957773396 scopus 로고    scopus 로고
    • Assessing the impact of breakthrough cancer pain
    • Burton B, Zeppetella G. Assessing the impact of breakthrough cancer pain. Br J Nurs. 2011;20:S14, S16-S19.
    • Br J Nurs. 2011;20 , vol.14 S
    • Burton, B.1    Zeppetella, G.2
  • 8
    • 79954546802 scopus 로고    scopus 로고
    • Integrated strategies for the successful management of breakthrough cancer pain
    • Dickman A. Integrated strategies for the successful management of breakthrough cancer pain. Curr Opin Support Palliat Care. 2011;5: 8-14.
    • (2011) Curr Opin Support Palliat Care , vol.5 , pp. 8-14
    • Dickman, A.1
  • 9
    • 0036176288 scopus 로고    scopus 로고
    • A survey of pain-related hospitalizations, emergency department visits, and physician office visits reported by cancer patients with and without history of breakthrough pain
    • Fortner BV, Okon TA, Portenoy RK. A survey of pain-related hospitalizations, emergency department visits, and physician office visits reported by cancer patients with and without history of breakthrough pain. J Pain. 2002;3:38-44.
    • (2002) J Pain , vol.3 , pp. 38-44
    • Fortner, B.V.1    Okon, T.A.2    Portenoy, R.K.3
  • 10
    • 33947356595 scopus 로고    scopus 로고
    • Impact of breakthrough pain on quality of life in patients with chronic, noncancer pain: Patient perceptions and effect of treatment with oral transmucosal fentanyl citrate (OTFC, ACTIQ)
    • Taylor D., Webster LR, Chun SY, et al. Impact of breakthrough pain on quality of life in patients with chronic, noncancer pain: patient perceptions and effect of treatment with oral transmucosal fentanyl citrate (OTFC, ACTIQ). Pain Med. 2007;8:281-288.
    • (2007) Pain Med , vol.8 , pp. 281-288
    • Taylor, D.1    Webster, L.R.2    Chun, S.Y.3
  • 11
    • 33846385707 scopus 로고    scopus 로고
    • Recognition and diagnosis of breakthrough pain
    • Payne R. Recognition and diagnosis of breakthrough pain. Pain Med. 2007;8 Suppl 1:S3-S7.
    • (2007) Pain Med , Issue.SUPPL. 1
    • Payne, R.1
  • 12
    • 0037406025 scopus 로고    scopus 로고
    • Clinically important changes in acute pain outcome measures: A validation study
    • Farrar JT, Berlin JA, Strom BL. Clinically important changes in acute pain outcome measures: a validation study. J Pain Symptom Manage. 2003;25:406-411.
    • (2003) J Pain Symptom Manage , vol.25 , pp. 406-411
    • Farrar, J.T.1    Berlin, J.A.2    Strom, B.L.3
  • 14
    • 19344374700 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic modeling of opioids
    • Lotsch J. Pharmacokinetic-pharmacodynamic modeling of opioids. J Pain Symptom Manage. 2005;29:S90-S103.
    • (2005) J Pain Symptom Manage , vol.29
    • Lotsch, J.1
  • 15
    • 0036468726 scopus 로고    scopus 로고
    • Episodic (breakthrough) pain: Consensus conference of an expert working group of the European Association for Palliative Care
    • Mercadante S, Radbruch L, Caraceni A, et al. Episodic (breakthrough) pain: consensus conference of an expert working group of the European Association for Palliative Care. Cancer. 2002;94:832-839.
    • (2002) Cancer , vol.94 , pp. 832-839
    • Mercadante, S.1    Radbruch, L.2    Caraceni, A.3
  • 16
    • 68149181408 scopus 로고    scopus 로고
    • Dynamics of breakthrough pain vs pharmacokinetics of oral morphine: Implications for management
    • Zeppetella G. Dynamics of breakthrough pain vs pharmacokinetics of oral morphine: implications for management. Eur J Cancer Care (Engl). 2009;18:331-337.
    • (2009) Eur J Cancer Care (Engl) , vol.18 , pp. 331-337
    • Zeppetella, G.1
  • 17
    • 43049104583 scopus 로고    scopus 로고
    • Opioids for cancer breakthrough pain: A pilot study reporting patient assessment of time to meaningful pain relief
    • Zeppetella G. Opioids for cancer breakthrough pain: a pilot study reporting patient assessment of time to meaningful pain relief. J Pain Symptom Manage. 2008;35:563-567.
    • (2008) J Pain Symptom Manage , vol.35 , pp. 563-567
    • Zeppetella, G.1
  • 18
    • 84863726672 scopus 로고    scopus 로고
    • Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects
    • Hoeben E, Smit JW, Upmalis D, et al. Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects. Pain. 2012;153:1648-1656.
    • (2012) Pain , vol.153 , pp. 1648-1656
    • Hoeben, E.1    Smit, J.W.2    Upmalis, D.3
  • 19
    • 84873501042 scopus 로고    scopus 로고
    • Food and Drug Administration, Available from, Accessed January 23, 2013
    • Food and Drug Administration. Transmucosal immediate release fentanyl (TIRF) risk evaluation and mitigation strategy (REMS). 2012. Available from: http://www.fda.gov/downloads/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/UCM289730.pdf. Accessed January 23, 2013.
    • (2012) Transmucosal Immediate Release Fentanyl (TIRF) Risk Evaluation and Mitigation Strategy (REMS)
  • 20
    • 0021979044 scopus 로고
    • EEG quantitation of narcotic effect: The comparative pharmacodynamics of fentanyl and alfentanil
    • Scott JC, Ponganis KV, Stanski DR. EEG quantitation of narcotic effect: the comparative pharmacodynamics of fentanyl and alfentanil. Anesthesiology. 1985;62:234-241.
    • (1985) Anesthesiology , vol.62 , pp. 234-241
    • Scott, J.C.1    Ponganis, K.V.2    Stanski, D.R.3
  • 21
    • 73349103141 scopus 로고    scopus 로고
    • Formulations of fentanyl for the management of pain
    • Grape S, Schug SA, Lauer S, Schug BS. Formulations of fentanyl for the management of pain. Drugs. 2010;70:57-72.
    • (2010) Drugs , vol.70 , pp. 57-72
    • Grape, S.1    Schug, S.A.2    Lauer, S.3    Schug, B.S.4
  • 22
    • 84875325788 scopus 로고    scopus 로고
    • Cephalon, FENTORA® (fentanyl buccal tablet) [package insert]. Salt Lake City, Cephalon, Inc
    • Cephalon. FENTORA® (fentanyl buccal tablet) [package insert]. Salt Lake City: Cephalon, Inc.; 2011.
    • (2011)
  • 23
    • 0023184219 scopus 로고
    • Monoamine oxidase inhibitors and narcotic analgesics. A critical review of the implications for treatment
    • Browne B, Linter S. Monoamine oxidase inhibitors and narcotic analgesics. A critical review of the implications for treatment. Br J Psychiatry. 1987;151:210-212.
    • (1987) Br J Psychiatry , vol.151 , pp. 210-212
    • Browne, B.1    Linter, S.2
  • 24
    • 0028226975 scopus 로고
    • Cardiac surgery in a patient taking monoamine oxidase inhibitors: An adverse fentanyl reaction
    • Insler SR, Kraenzler EJ, Licina MG, Savage RM, Starr NJ. Cardiac surgery in a patient taking monoamine oxidase inhibitors: an adverse fentanyl reaction. Anesth Analg. 1994;78:593-597.
    • (1994) Anesth Analg , vol.78 , pp. 593-597
    • Insler, S.R.1    Kraenzler, E.J.2    Licina, M.G.3    Savage, R.M.4    Starr, N.J.5
  • 25
    • 84861864824 scopus 로고    scopus 로고
    • Food and Drug Administration, [press release]. Silver Spring (MD): FDA; September 26, 2007. Available from, Accessed June 1, 2011
    • Food and Drug Administration. FDA warns of potential serious side effects with breakthrough cancer pain drug [press release]. Silver Spring (MD): FDA; September 26, 2007. Available from: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2007/ucm108994.htm. Accessed June 1, 2011.
    • FDA Warns of Potential Serious Side Effects With Breakthrough Cancer Pain Drug
  • 26
    • 0017081059 scopus 로고
    • Components of respiratory depression after narcotic premedication in adolescents
    • Knill R, Cosgrove JF, Olley PM, Levison H. Components of respiratory depression after narcotic premedication in adolescents. Can Anaesth Soc J. 1976;23:449-458.
    • (1976) Can Anaesth Soc J , vol.23 , pp. 449-458
    • Knill, R.1    Cosgrove, J.F.2    Olley, P.M.3    Levison, H.4
  • 27
    • 0017129899 scopus 로고
    • Recovery of ventilatory response to carbon dioxide after thiopentone, morphine and fentanyl in man
    • Rigg JR, Goldsmith CH. Recovery of ventilatory response to carbon dioxide after thiopentone, morphine and fentanyl in man. Can Anaesth Soc J. 1976;23:370-382.
    • (1976) Can Anaesth Soc J , vol.23 , pp. 370-382
    • Rigg, J.R.1    Goldsmith, C.H.2
  • 28
    • 84875330013 scopus 로고    scopus 로고
    • Cephalon, ACTIQ® (oral transmucosal fentanyl citrate) [package insert]. Salt Lake City, Cephalon, Inc
    • Cephalon. ACTIQ® (oral transmucosal fentanyl citrate) [package insert]. Salt Lake City: Cephalon, Inc.; 2011.
    • (2011)
  • 29
    • 84875326611 scopus 로고    scopus 로고
    • Meda Pharmaceuticals. ONSOLIS® (fentanyl buccal soluble film) [package insert]. Somerset (NJ), Meda Pharmaceuticals, Inc
    • Meda Pharmaceuticals. ONSOLIS® (fentanyl buccal soluble film) [package insert]. Somerset (NJ): Meda Pharmaceuticals, Inc.; 2009.
    • (2009)
  • 30
    • 84875292991 scopus 로고    scopus 로고
    • ProStrakan. ABSTRAL®(fentanyl sublingual tablets) [package insert]. Bedminster (NJ), ProStrakan, Inc
    • ProStrakan. ABSTRAL®(fentanyl sublingual tablets) [package insert]. Bedminster (NJ): ProStrakan, Inc.; 2011.
    • (2011)
  • 31
    • 84875357318 scopus 로고    scopus 로고
    • Insys Therapeutics. SUBSYS™ (fentanyl sublingual spray) [package insert]. Phoenix, Insys Therapeutics, Inc
    • Insys Therapeutics. SUBSYS™ (fentanyl sublingual spray) [package insert]. Phoenix: Insys Therapeutics, Inc.; 2012.
    • (2012)
  • 32
    • 84875352875 scopus 로고    scopus 로고
    • Nycomed Danmark. Instanyl® (intranasal fentanyl nasal spray) [summary of product characteristics]. Roskilde, Denmark, Nycomed Danmark Aps
    • Nycomed Danmark. Instanyl® (intranasal fentanyl nasal spray) [summary of product characteristics]. Roskilde, Denmark: Nycomed Danmark Aps; 2011.
    • (2011)
  • 33
    • 84875351558 scopus 로고    scopus 로고
    • Archimedes Pharma. Lazanda® (fentanyl pectin nasal spray) [package insert]. Bedminster (NJ), Archimedes Pharma, Inc
    • Archimedes Pharma. Lazanda® (fentanyl pectin nasal spray) [package insert]. Bedminster (NJ): Archimedes Pharma, Inc.; 2011.
    • (2011)
  • 34
    • 33847772352 scopus 로고    scopus 로고
    • Oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients: An overview of its pharmacological and clinical characteristics
    • Mystakidou K, Katsouda E, Parpa E, Tsiatas ML, Vlahos L. Oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients: an overview of its pharmacological and clinical characteristics. J Opioid Manag. 2005;1:36-40.
    • (2005) J Opioid Manag , vol.1 , pp. 36-40
    • Mystakidou, K.1    Katsouda, E.2    Parpa, E.3    Tsiatas, M.L.4    Vlahos, L.5
  • 36
  • 37
    • 0032522607 scopus 로고    scopus 로고
    • Oral transmucosal fentanyl citrate: Randomized, double-blinded, placebo-controlled trial for treatment of breakthrough pain in cancer patients
    • Farrar JT, Cleary J, Rauck R, Busch M, Nordbrock E. Oral transmucosal fentanyl citrate: randomized, double-blinded, placebo-controlled trial for treatment of breakthrough pain in cancer patients. J Natl Cancer Inst. 1998;90:611-616.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 611-616
    • Farrar, J.T.1    Cleary, J.2    Rauck, R.3    Busch, M.4    Nordbrock, E.5
  • 38
    • 0035059131 scopus 로고    scopus 로고
    • Breakthrough cancer pain: A randomized trial comparing oral transmucosal fentanyl citrate (OTFC) and morphine sulfate immediate release (MSIR)
    • Coluzzi PH, Schwartzberg L, Conroy JD, et al. Breakthrough cancer pain: a randomized trial comparing oral transmucosal fentanyl citrate (OTFC) and morphine sulfate immediate release (MSIR). Pain. 2001;91:123-130.
    • (2001) Pain , vol.91 , pp. 123-130
    • Coluzzi, P.H.1    Schwartzberg, L.2    Conroy, J.D.3
  • 39
    • 0031759360 scopus 로고    scopus 로고
    • Dose-titration, multicenter study of oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients using transdermal fentanyl for persistent pain
    • Christie JM, Simmonds M, Patt R, et al. Dose-titration, multicenter study of oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients using transdermal fentanyl for persistent pain. J Clin Oncol. 1998;16:3238-3245.
    • (1998) J Clin Oncol , vol.16 , pp. 3238-3245
    • Christie, J.M.1    Simmonds, M.2    Patt, R.3
  • 40
    • 0032981296 scopus 로고    scopus 로고
    • Oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough pain in cancer patients: A controlled dose titration study
    • Portenoy RK, Payne R, Coluzzi P, et al. Oral transmucosal fentanyl citrate (OTFC) for the treatment of breakthrough pain in cancer patients: a controlled dose titration study. Pain. 1999;79: 303-312.
    • (1999) Pain , vol.79 , pp. 303-312
    • Portenoy, R.K.1    Payne, R.2    Coluzzi, P.3
  • 42
    • 19744366577 scopus 로고    scopus 로고
    • Oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients: An overview of its pharmacological and clinical characteristics
    • Mystakidou K, Katsouda E, Parpa E, Tsiatas ML, Vlahos L. Oral transmucosal fentanyl citrate for the treatment of breakthrough pain in cancer patients: an overview of its pharmacological and clinical characteristics. Am J Hosp Palliat Care. 2005;22:228-232.
    • (2005) Am J Hosp Palliat Care , vol.22 , pp. 228-232
    • Mystakidou, K.1    Katsouda, E.2    Parpa, E.3    Tsiatas, M.L.4    Vlahos, L.5
  • 45
    • 34548605294 scopus 로고    scopus 로고
    • Effect of buccal dwell time on the pharmacokinetic profile of fentanyl buccal tablet
    • Darwish M, Kirby M, Jiang JG. Effect of buccal dwell time on the pharmacokinetic profile of fentanyl buccal tablet. Expert Opin Pharmacother. 2007;8:2011-2016.
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 2011-2016
    • Darwish, M.1    Kirby, M.2    Jiang, J.G.3
  • 46
    • 77952078392 scopus 로고    scopus 로고
    • Dose proportionality of fentanyl buccal tablet in doses ranging from 600 to 1300 microg in healthy adult subjects: A randomized, open-label, four-period, crossover, single-centre study
    • Darwish M, Kirby M, Robertson P Jr, Tracewell W, Xie F. Dose proportionality of fentanyl buccal tablet in doses ranging from 600 to 1300 microg in healthy adult subjects: a randomized, open-label, four-period, crossover, single-centre study. Clin Drug Investig. 2010;30:365-373.
    • (2010) Clin Drug Investig , vol.30 , pp. 365-373
    • Darwish, M.1    Kirby, M.2    Robertson Jr., P.3    Tracewell, W.4    Xie, F.5
  • 47
    • 33746849278 scopus 로고    scopus 로고
    • Relative bioavailability of the fentanyl effervescent buccal tablet (FEBT) 1,080 pg versus oral transmucosal fentanyl citrate 1,600 pg and dose proportionality of FEBT 270 to 1,300 microg: A single-dose, randomized, open-label, three-period study in healthy adult volunteers
    • Darwish M, Tempero K, Kirby M, Thompson J. Relative bioavailability of the fentanyl effervescent buccal tablet (FEBT) 1,080 pg versus oral transmucosal fentanyl citrate 1,600 pg and dose proportionality of FEBT 270 to 1,300 microg: a single-dose, randomized, open-label, three-period study in healthy adult volunteers. Clin Ther. 2006;28:715-724.
    • (2006) Clin Ther , vol.28 , pp. 715-724
    • Darwish, M.1    Tempero, K.2    Kirby, M.3    Thompson, J.4
  • 48
    • 33745972464 scopus 로고    scopus 로고
    • Pharmacokinetic properties of fentanyl effervescent buccal tablets: A phase I, open-label, crossover study of single-dose 100, 200, 400, and 800 microg in healthy adult volunteers
    • Darwish M, Kirby M, Robertson P Jr, Tracewell W, Jiang JG. Pharmacokinetic properties of fentanyl effervescent buccal tablets: a phase I, open-label, crossover study of single-dose 100, 200, 400, and 800 microg in healthy adult volunteers. Clin Ther. 2006;28: 707-714.
    • (2006) Clin Ther , vol.28 , pp. 707-714
    • Darwish, M.1    Kirby, M.2    Robertson Jr., P.3    Tracewell, W.4    Jiang, J.G.5
  • 49
    • 33847154665 scopus 로고    scopus 로고
    • Absolute and relative bioavailability of fentanyl buccal tablet and oral transmucosal fentanyl citrate
    • Darwish M, Kirby M, Robertson P Jr, Tracewell W, Jiang JG. Absolute and relative bioavailability of fentanyl buccal tablet and oral transmucosal fentanyl citrate. J Clin Pharmacol. 2007;47:343-350.
    • (2007) J Clin Pharmacol , vol.47 , pp. 343-350
    • Darwish, M.1    Kirby, M.2    Robertson Jr., P.3    Tracewell, W.4    Jiang, J.G.5
  • 50
    • 77956511264 scopus 로고    scopus 로고
    • A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioid-tolerant patients with noncancer-related chronic pain
    • Farrar JT, Messina J, Xie F, Portenoy RK. A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioid-tolerant patients with noncancer-related chronic pain. Pain Med. 2010;11:1313-1327.
    • (2010) Pain Med , vol.11 , pp. 1313-1327
    • Farrar, J.T.1    Messina, J.2    Xie, F.3    Portenoy, R.K.4
  • 51
    • 33750322229 scopus 로고    scopus 로고
    • A randomized, placebo-controlled study of fentanyl buccal tablet for breakthrough pain in opioid-treated patients with cancer
    • Portenoy RK, Taylor D, Messina J, Tremmel L. A randomized, placebo-controlled study of fentanyl buccal tablet for breakthrough pain in opioid-treated patients with cancer. Clin J Pain. 2006;22: 805-811.
    • (2006) Clin J Pain , vol.22 , pp. 805-811
    • Portenoy, R.K.1    Taylor, D.2    Messina, J.3    Tremmel, L.4
  • 52
    • 33846692601 scopus 로고    scopus 로고
    • Fentanyl buccal tablet (FBT) for relief of breakthrough pain in opioid-treated patients with chronic low back pain: A randomized, placebo-controlled study
    • Portenoy RK, Messina J, Xie F, Peppin J. Fentanyl buccal tablet (FBT) for relief of breakthrough pain in opioid-treated patients with chronic low back pain: a randomized, placebo-controlled study. Curr Med Res Opin. 2007;23:223-233.
    • (2007) Curr Med Res Opin , vol.23 , pp. 223-233
    • Portenoy, R.K.1    Messina, J.2    Xie, F.3    Peppin, J.4
  • 53
    • 34347328100 scopus 로고    scopus 로고
    • Fentanyl buccal tablet for the relief of breakthrough pain in opioid-tolerant adult patients with chronic neuropathic pain: A multicenter, randomized, double-blind, placebo-controlled study
    • Simpson DM, Messina J, Xie F, Hale M. Fentanyl buccal tablet for the relief of breakthrough pain in opioid-tolerant adult patients with chronic neuropathic pain: a multicenter, randomized, double-blind, placebo-controlled study. Clin Ther. 2007;29:588-601.
    • (2007) Clin Ther , vol.29 , pp. 588-601
    • Simpson, D.M.1    Messina, J.2    Xie, F.3    Hale, M.4
  • 54
    • 34948821962 scopus 로고    scopus 로고
    • Fentanyl buccal tablet for relief of breakthrough pain in opioid-tolerant patients with cancer-related chronic pain
    • Slatkin NE, Xie F, Messina J, Segal TJ. Fentanyl buccal tablet for relief of breakthrough pain in opioid-tolerant patients with cancer-related chronic pain. J Support Oncol. 2007;5:327-334.
    • (2007) J Support Oncol , vol.5 , pp. 327-334
    • Slatkin, N.E.1    Xie, F.2    Messina, J.3    Segal, T.J.4
  • 55
    • 79952448795 scopus 로고    scopus 로고
    • The efficacy and safety of fentanyl buccal tablet compared with immediate-release oxycodone for the management of breakthrough pain in opioid-tolerant patients with chronic pain
    • Ashburn MA, Slevin KA, Messina J, Xie F. The efficacy and safety of fentanyl buccal tablet compared with immediate-release oxycodone for the management of breakthrough pain in opioid-tolerant patients with chronic pain. Anesth Analg. 2011;112:693-702.
    • (2011) Anesth Analg , vol.112 , pp. 693-702
    • Ashburn, M.A.1    Slevin, K.A.2    Messina, J.3    Xie, F.4
  • 56
    • 66649114524 scopus 로고    scopus 로고
    • Fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic cancer pain: A long-term, open-label safety study
    • Weinstein SM, Messina J, Xie F. Fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic cancer pain: a long-term, open-label safety study. Cancer. 2009;115:2571-2579.
    • (2009) Cancer , vol.115 , pp. 2571-2579
    • Weinstein, S.M.1    Messina, J.2    Xie, F.3
  • 57
    • 77955130750 scopus 로고    scopus 로고
    • Long-term safety and tolerability of fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic pain: An 18-month study
    • Fine PG, Messina J, Xie F, Rathmell J. Long-term safety and tolerability of fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic pain: an 18-month study. J Pain Symptom Manage. 2010;40:747-760.
    • (2010) J Pain Symptom Manage , vol.40 , pp. 747-760
    • Fine, P.G.1    Messina, J.2    Xie, F.3    Rathmell, J.4
  • 58
    • 77955129007 scopus 로고    scopus 로고
    • Single-dose pharmacokinetics of fentanyl buccal soluble film
    • Vasisht N, Gever LN, Tagarro I, Finn AL. Single-dose pharmacokinetics of fentanyl buccal soluble film. Pain Med. 2010;11:1017-1023.
    • (2010) Pain Med , vol.11 , pp. 1017-1023
    • Vasisht, N.1    Gever, L.N.2    Tagarro, I.3    Finn, A.L.4
  • 59
    • 82555194576 scopus 로고    scopus 로고
    • Dose proportionality and pharmacokinetics of fentanyl buccal soluble film in healthy subjects: A phase I, open-label, three-period, crossover study
    • Finn AL, Vasisht N, Stark JG, Gever LN, Tagarro I. Dose proportionality and pharmacokinetics of fentanyl buccal soluble film in healthy subjects: a phase I, open-label, three-period, crossover study. Clin Drug Investig. 2012;32:63-71.
    • (2012) Clin Drug Investig , vol.32 , pp. 63-71
    • Finn, A.L.1    Vasisht, N.2    Stark, J.G.3    Gever, L.N.4    Tagarro, I.5
  • 60
    • 79953831361 scopus 로고    scopus 로고
    • Intra- and interindividual variabilities in the pharmacokinetics of fentanyl buccal soluble film in healthy subjects: A cross-study analysis
    • Davies A, Finn A, Tagarro I. Intra- and interindividual variabilities in the pharmacokinetics of fentanyl buccal soluble film in healthy subjects: a cross-study analysis. Clin Drug Investig. 2011;31:317-324.
    • (2011) Clin Drug Investig , vol.31 , pp. 317-324
    • Davies, A.1    Finn, A.2    Tagarro, I.3
  • 61
    • 84856176066 scopus 로고    scopus 로고
    • Absorption and tolerability of fentanyl buccal soluble film (FBSF) in patients with cancer in the presence of oral mucositis
    • Finn AL, Hill WC, Tagarro I, Gever LN. Absorption and tolerability of fentanyl buccal soluble film (FBSF) in patients with cancer in the presence of oral mucositis. J Pain Res. 2011;4:245-251.
    • (2011) J Pain Res , vol.4 , pp. 245-251
    • Finn, A.L.1    Hill, W.C.2    Tagarro, I.3    Gever, L.N.4
  • 62
    • 69549101611 scopus 로고    scopus 로고
    • Formulation selection and pharmacokinetic comparison of fentanyl buccal soluble film with oral transmucosal fentanyl citrate: A randomized, open-label, single-dose, crossover study
    • Vasisht N, Gever LN, Tagarro I, Finn AL. Formulation selection and pharmacokinetic comparison of fentanyl buccal soluble film with oral transmucosal fentanyl citrate: a randomized, open-label, single-dose, crossover study. Clin Drug Investig. 2009;29:647-654.
    • (2009) Clin Drug Investig , vol.29 , pp. 647-654
    • Vasisht, N.1    Gever, L.N.2    Tagarro, I.3    Finn, A.L.4
  • 63
    • 77951618928 scopus 로고    scopus 로고
    • Fentanyl buccal soluble film (FBSF) for breakthrough pain in patients with cancer: A randomized, double-blind, placebo-controlled study
    • Rauck R, North J, Gever LN, Tagarro I, Finn AL. Fentanyl buccal soluble film (FBSF) for breakthrough pain in patients with cancer: a randomized, double-blind, placebo-controlled study. Ann Oncol. 2010;21:1308-1314.
    • (2010) Ann Oncol , vol.21 , pp. 1308-1314
    • Rauck, R.1    North, J.2    Gever, L.N.3    Tagarro, I.4    Finn, A.L.5
  • 64
    • 13444274550 scopus 로고    scopus 로고
    • Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: A new approach to treatment of incident pain
    • Lennernas B, Hedner T, Holmberg M, Bredenberg S, Nystrom C, Lennernas H. Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain. Br J Clin Pharmacol. 2005;59:249-253.
    • (2005) Br J Clin Pharmacol , vol.59 , pp. 249-253
    • Lennernas, B.1    Hedner, T.2    Holmberg, M.3    Bredenberg, S.4    Nystrom, C.5    Lennernas, H.6
  • 65
    • 72549117859 scopus 로고    scopus 로고
    • Efficacy and long-term tolerability of sublingual fentanyl orally disintegrating tablet in the treatment of breakthrough cancer pain
    • Rauck RL, Tark M, Reyes E, et al. Efficacy and long-term tolerability of sublingual fentanyl orally disintegrating tablet in the treatment of breakthrough cancer pain. Curr Med Res Opin. 2009;25: 2877-2885.
    • (2009) Curr Med Res Opin , vol.25 , pp. 2877-2885
    • Rauck, R.L.1    Tark, M.2    Reyes, E.3
  • 66
    • 79951627761 scopus 로고    scopus 로고
    • Long-term effectiveness and tolerability of sublingual fentanyl orally disintegrating tablet for the treatment of breakthrough cancer pain
    • Nalamachu S, Hassman D, Wallace MS, Dumble S, Derrick R, Howell J. Long-term effectiveness and tolerability of sublingual fentanyl orally disintegrating tablet for the treatment of breakthrough cancer pain. Curr Med Res Opin. 2011;27:519-530.
    • (2011) Curr Med Res Opin , vol.27 , pp. 519-530
    • Nalamachu, S.1    Hassman, D.2    Wallace, M.S.3    Dumble, S.4    Derrick, R.5    Howell, J.6
  • 67
    • 84861120406 scopus 로고    scopus 로고
    • Efficacy and safety of fentanyl sublingual spray for the treatment of breakthrough cancer pain: A randomized, double-blind, placebo-controlled study
    • Rauck R, Reynolds L, Geach J, et al. Efficacy and safety of fentanyl sublingual spray for the treatment of breakthrough cancer pain: a randomized, double-blind, placebo-controlled study. Curr Med Res Opin. 2012;28:859-870.
    • (2012) Curr Med Res Opin , vol.28 , pp. 859-870
    • Rauck, R.1    Reynolds, L.2    Geach, J.3
  • 68
    • 68949120909 scopus 로고    scopus 로고
    • Efficacy and tolerability of intranasal fentanyl spray 50 to 200 microg for breakthrough pain in patients with cancer: A phase III, multinational, randomized, double-blind, placebo-controlled, crossover trial with a 10-month, open-label extension treatment period
    • Kress HG, Oronska A, Kaczmarek Z, Kaasa S, Colberg T, Nolte T. Efficacy and tolerability of intranasal fentanyl spray 50 to 200 microg for breakthrough pain in patients with cancer: a phase III, multinational, randomized, double-blind, placebo-controlled, crossover trial with a 10-month, open-label extension treatment period. Clin Ther. 2009;31:1177-1191.
    • (2009) Clin Ther , vol.31 , pp. 1177-1191
    • Kress, H.G.1    Oronska, A.2    Kaczmarek, Z.3    Kaasa, S.4    Colberg, T.5    Nolte, T.6
  • 69
    • 72549097280 scopus 로고    scopus 로고
    • A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: An open-label, randomised, crossover trial
    • Mercadante S, Radbruch L, Davies A, et al. A comparison of intranasal fentanyl spray with oral transmucosal fentanyl citrate for the treatment of breakthrough cancer pain: an open-label, randomised, crossover trial. Curr Med Res Opin. 2009;25:2805-2815.
    • (2009) Curr Med Res Opin , vol.25 , pp. 2805-2815
    • Mercadante, S.1    Radbruch, L.2    Davies, A.3
  • 70
    • 78650820821 scopus 로고    scopus 로고
    • Pharmacokinetics and relative bioavailability of fentanyl pectin nasal spray 100-800 microg in healthy volunteers
    • Fisher A, Watling M, Smith A, Knight A. Pharmacokinetics and relative bioavailability of fentanyl pectin nasal spray 100-800 microg in healthy volunteers. Int J Clin Pharmacol Ther. 2010;48:860-867.
    • (2010) Int J Clin Pharmacol Ther , vol.48 , pp. 860-867
    • Fisher, A.1    Watling, M.2    Smith, A.3    Knight, A.4
  • 71
    • 67649229310 scopus 로고    scopus 로고
    • PecSys: In situ gelling system for optimised nasal drug delivery
    • Watts P, Smith A. PecSys: in situ gelling system for optimised nasal drug delivery. Expert Opin Drug Deliv. 2009;6:543-552.
    • (2009) Expert Opin Drug Deliv , vol.6 , pp. 543-552
    • Watts, P.1    Smith, A.2
  • 72
    • 78049464453 scopus 로고    scopus 로고
    • A multicenter, placebo-controlled, double-blind, multiple-crossover study of fentanyl pectin nasal spray (FPNS) in the treatment of breakthrough cancer pain
    • Portenoy RK, Burton AW, Gabrail N, Taylor D. A multicenter, placebo-controlled, double-blind, multiple-crossover study of fentanyl pectin nasal spray (FPNS) in the treatment of breakthrough cancer pain. Pain. 2010;151:617-624.
    • (2010) Pain , vol.151 , pp. 617-624
    • Portenoy, R.K.1    Burton, A.W.2    Gabrail, N.3    Taylor, D.4
  • 73
    • 79951877274 scopus 로고    scopus 로고
    • Consistency of efficacy, patient acceptability, and nasal tolerability of fentanyl pectin nasal spray compared with immediate-release morphine sulfate in breakthrough cancer pain
    • Davies A, Sitte T, Elsner F, et al. Consistency of efficacy, patient acceptability, and nasal tolerability of fentanyl pectin nasal spray compared with immediate-release morphine sulfate in breakthrough cancer pain. J Pain Symptom Manage. 2011;41:358-366.
    • (2011) J Pain Symptom Manage , vol.41 , pp. 358-366
    • Davies, A.1    Sitte, T.2    Elsner, F.3
  • 74
    • 80051511227 scopus 로고    scopus 로고
    • Newer generation fentanyl transmucosal products for breakthrough pain in opioid-tolerant cancer patients
    • Elsner F, Zeppetella G, Porta-Sales J, Tagarro I. Newer generation fentanyl transmucosal products for breakthrough pain in opioid-tolerant cancer patients. Clin Drug Investig. 2011;31:605-618.
    • (2011) Clin Drug Investig , vol.31 , pp. 605-618
    • Elsner, F.1    Zeppetella, G.2    Porta-Sales, J.3    Tagarro, I.4
  • 75
    • 79952930728 scopus 로고    scopus 로고
    • Opioid delivery in the treatment of cancer breakthrough pain: A review of routes of administration
    • Nicholson B, Agarwala SS. Opioid delivery in the treatment of cancer breakthrough pain: a review of routes of administration. J Opioid Manag. 2011;7:69-79.
    • (2011) J Opioid Manag , vol.7 , pp. 69-79
    • Nicholson, B.1    Agarwala, S.S.2
  • 76
    • 34548077818 scopus 로고    scopus 로고
    • Absorption of fentanyl from fentanyl buccal tablet in cancer patients with or without oral mucositis: A pilot study
    • Darwish M, Kirby M, Robertson P, Tracewell W, Jiang JG. Absorption of fentanyl from fentanyl buccal tablet in cancer patients with or without oral mucositis: a pilot study. Clin Drug Investig. 2007;27:605-611.
    • (2007) Clin Drug Investig , vol.27 , pp. 605-611
    • Darwish, M.1    Kirby, M.2    Robertson, P.3    Tracewell, W.4    Jiang, J.G.5
  • 77
    • 0037247824 scopus 로고    scopus 로고
    • The acceptability of different routes of administration of analgesia for breakthrough pain
    • Walker G, Wilcock A, Manderson C, Weller R, Crosby V. The acceptability of different routes of administration of analgesia for breakthrough pain. Palliat Med. 2003;17:219-221.
    • (2003) Palliat Med , vol.17 , pp. 219-221
    • Walker, G.1    Wilcock, A.2    Manderson, C.3    Weller, R.4    Crosby, V.5
  • 78
    • 79957710013 scopus 로고    scopus 로고
    • Multi-centre European study of breakthrough cancer pain: Pain characteristics and patient perceptions of current and potential management strategies
    • Davies A, Zeppetella G, Andersen S, et al. Multi-centre European study of breakthrough cancer pain: pain characteristics and patient perceptions of current and potential management strategies. Eur J Pain. 2011;15:756-763.
    • (2011) Eur J Pain , vol.15 , pp. 756-763
    • Davies, A.1    Zeppetella, G.2    Andersen, S.3
  • 79
    • 58949087688 scopus 로고    scopus 로고
    • Opioids for chronic noncancer pain: Prediction and identification of aberrant drug-related behaviors: A review of the evidence for an American Pain Society and American Academy of Pain Medicine clinical practice guideline
    • Chou R, Fanciullo GJ, Fine PG, Miaskowski C, Passik SD, Portenoy RK. Opioids for chronic noncancer pain: prediction and identification of aberrant drug-related behaviors: a review of the evidence for an American Pain Society and American Academy of Pain Medicine clinical practice guideline. J Pain. 2009;10:131-146.
    • (2009) J Pain , vol.10 , pp. 131-146
    • Chou, R.1    Fanciullo, G.J.2    Fine, P.G.3    Miaskowski, C.4    Passik, S.D.5    Portenoy, R.K.6
  • 80
    • 70949088843 scopus 로고    scopus 로고
    • A comparison of common screening methods for predicting aberrant drug-related behavior among patients receiving opioids for chronic pain management
    • Moore TM, Jones T, Browder JH, Daffron S, Passik SD. A comparison of common screening methods for predicting aberrant drug-related behavior among patients receiving opioids for chronic pain management. Pain Med. 2009;10:1426-1433.
    • (2009) Pain Med , vol.10 , pp. 1426-1433
    • Moore, T.M.1    Jones, T.2    Browder, J.H.3    Daffron, S.4    Passik, S.D.5
  • 81
    • 0036232961 scopus 로고    scopus 로고
    • The role of ketamine in preventing fentanyl-induced hyperalgesia and subsequent acute morphine tolerance
    • table of contents
    • Laulin JP, Maurette P, Corcuff JB, Rivat C, Chauvin M, Simonnet G. The role of ketamine in preventing fentanyl-induced hyperalgesia and subsequent acute morphine tolerance. Anesth Analg. 2002;94:1263-1269, table of contents.
    • (2002) Anesth Analg , vol.94 , pp. 1263-1269
    • Laulin, J.P.1    Maurette, P.2    Corcuff, J.B.3    Rivat, C.4    Chauvin, M.5    Simonnet, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.