Combined treatment with peroxisome proliferator-activated receptor (PPAR) gamma ligands and gamma radiation induces apoptosis by PPARγ-independent up-regulation of reactive oxygen species-induced deoxyribonucleic acid damage signals in non-small cell lung cancer cells

International Journal of Radiation Oncology Biology Physics

Volumn 85, Issue 5, 2013, Pages

  Han, Eun Jong ^a   Im, Chang Nim ^a   Park, Seon Hwa ^a   Moon, Eun Yi ^b   Hong, Sung Hee ^a  

^a Korea Institute of Radiation and Medical Science   (South Korea)

^b Sejong University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

COMBINATION TREATMENTS; METHODS AND MATERIALS; NON SMALL CELL LUNG CANCER; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; POLY(ADP-RIBOSE) POLYMERASE; RADIATION-INDUCED APOPTOSIS; REACTIVE OXYGEN SPECIES; ROS SCAVENGER N-ACETYLCYSTEINE;

ACTIVATION ANALYSIS; BIOACTIVITY; BIOLOGICAL ORGANS; CELL DEATH; DNA; FLOW CYTOMETRY; ORGANIC ACIDS; OXYGEN; RADIOTHERAPY;

LIGANDS;

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CAY 10415; CAY 10506; CELL DNA; CIGLITAZONE; DICHLORODIHYDROFLUORESCEIN DIACETATE; HISTONE H2AX; LIGAND; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER RADIOTHERAPY; CELL ASSAY; CELL DEATH; CELL FRACTIONATION; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DRUG ACTIVITY; ENZYME ACTIVATION; FLOW CYTOMETRY; GAMMA RADIATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; RADIOSENSITIZATION; UPREGULATION;

APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CASPASE 3; CASPASE 8; DNA DAMAGE; FLUORESCEINS; GAMMA RAYS; HISTONES; HUMANS; LUNG NEOPLASMS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; POLY(ADP-RIBOSE) POLYMERASES; PPAR GAMMA; RADIATION TOLERANCE; REACTIVE OXYGEN SPECIES; THIAZOLIDINEDIONES; TUMOR STEM CELL ASSAY;

EID: 84875271050     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2012.11.040     Document Type: Article

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