Salivary protein and solCD44 levels as a potential screening tool for early detection of head and neck squamous cell carcinoma

Head and Neck

Volumn 34, Issue 5, 2012, Pages 687-695

  Franzmann, Elizabeth J ^a,b   Reategui, Erika P ^b   Pereira, Lutecia H Mateus ^a   Pedroso, Felipe ^c   Joseph, Debbie ^d   Allen, Glenn O ^a   Hamilton, Kara ^b   Reis, Isildinha ^b   Duncan, Robert ^b   Goodwin, W Jarrard ^a,b   Hu, Jennifer J ^a,b   Lokeshwar, Vinata B ^a,b  

^a UNIVERSITY OF MIAMI   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d UNIVERSITY OF FLORIDA   (United States)

Author keywords

ELISA assay; head and neck squamous cell carcinoma; protein; soluble CD44; upper aerodigestive tract

Indexed keywords

HERMES ANTIGEN; SALIVA PROTEIN;

ADULT; AREA UNDER THE CURVE; ARTICLE; CANCER DIAGNOSIS; CANCER SCREENING; CONTROLLED STUDY; DEMOGRAPHY; EARLY DIAGNOSIS; FEMALE; HEAD AND NECK CARCINOMA; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REGRESSION ANALYSIS; SQUAMOUS CELL CARCINOMA;

ANTIGENS, CD44; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; EARLY DIAGNOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROTEINS; ROC CURVE; SALIVA; SENSITIVITY AND SPECIFICITY; SMOKING; TUMOR MARKERS, BIOLOGICAL;

EID: 84859739851     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.21810     Document Type: Article

References (41)

1. American Cancer Society. Cancer Facts & Figures 2009. Atlanta: American Cancer Society; 2009.
2. Parkin DM, Bray F, Ferlay J, Pisani P,. Global cancer statistics, 2002. CA Cancer J Clin 2005; 55: 74-108.
3. Ries LAG, Young JL, Keel GE, Eisner MP, Lin YD, Horner M-J, editors. SEER Survival Monograph: Cancer Survival Among Adults: US SEER Program, 1988-2001, Patient and Tumor Characteristics. National Cancer Institute, SEER Program, NIH Pub. No. 07-6215, Bethesda, MD, 2007.
4. Forastiere A, Koch W, Trotti A, Sidransky D,. Head and neck cancer. N Engl J Med 2001; 345: 1890-1900.
5. Dolan RW, Vaughan CW, Fuleihan N,. Symptoms in early head and neck cancer: an inadequate indicator. Otolaryngol Head Neck Surg 1998; 119: 463-467.
6. Patton LL,. The effectiveness of community-based visual screening and utility of adjunctive diagnostic aids in the early detection of oral cancer. Oral Oncol 2003; 39: 708-723.
7. Sankaranarayanan R, Ramadas K, Thomas G, et al. Effect of screening on oral cancer mortality in Kerala, India: a cluster-randomised controlled trial. Lancet 2005; 365: 1927-1933.
8. Sankaranarayanan R, Mathew B, Jacob BJ, et al. Early findings from a community-based, cluster-randomized, controlled oral cancer screening trial in Kerala, India. The Trivandrum Oral Cancer Screening Study Group. Cancer 2000; 88: 664-673.
9. Wong DT,. Towards a simple, saliva-based test for the detection of oral cancer 'oral fluid (saliva), which is the mirror of the body, is a perfect medium to be explored for health and disease surveillance'. Expert Rev Mol Diagn 2006; 6: 267-272.
10. Neville BW, Day TA,. Oral cancer and precancerous lesions. CA Cancer J Clin 2002; 52: 195-215.
11. National Cancer Institute/US. Oral Cancers: research report. US Department of Health and Human Services, Public Health Service, National Institutes of Health 1991; NIH publication no. 92-2875.
12. Weinberg MA, Estefan DJ,. Assessing oral malignancies. Am Fam Physician 2002; 65: 1379-1384.
13. Spafford MF, Koch WM, Reed AL, et al. Detection of head and neck squamous cell carcinoma among exfoliated oral mucosal cells by microsatellite analysis. Clin Cancer Res 2001; 7: 607-612.
14. Boyle JO, Mao L, Brennan JA, et al. Gene mutations in saliva as molecular markers for head and neck squamous cell carcinomas. Am J Surg 1994; 168: 429-432.
15. St John MA, Li Y, Zhou X, et al. Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2004; 130: 929-935.
16. Li Y, St John MA, Zhou X, et al. Salivary transcriptome diagnostics for oral cancer detection. Clin Cancer Res 2004; 10: 8442-8450.
17. Park NJ, Zhou H, Elashoff D, et al. Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection. Clin Cancer Res 2009; 15: 5473-5477.
18. Hu S, Arellano M, Boontheung P, et al. Salivary proteomics for oral cancer biomarker discovery. Clin Cancer Res 2008; 14: 6246-6252.
19. Arellano-Garcia ME, Hu S, Wang J, et al. Multiplexed immunobead-based assay for detection of oral cancer protein biomarkers in saliva. Oral Dis 2008; 14: 705-712.
20. Carvalho AL, Jeronimo C, Kim MM, et al. Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma. Clin Cancer Res 2008; 14: 97-107.
21. Califano J, Ahrendt SA, Meininger G, Westra WH, Koch WM, Sidransky D,. Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients. Cancer Res 1996; 56: 5720-5722.
22. Chang SS, Jiang WW, Smith I, et al. MicroRNA alterations in head and neck squamous cell carcinoma. Int J Cancer 2008; 123: 2791-2797.
23. Wong TS, Liu XB, Wong BY, Ng RW, Yuen AP, Wei WI,. Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue. Clin Cancer Res 2008; 14: 2588-2592.
24. Kozaki K, Imoto I, Mogi S, Omura K, Inazawa J,. Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res 2008; 68: 2094-2105.
25. Avissar M, Christensen BC, Kelsey KT, Marsit CJ,. MicroRNA expression ratio is predictive of head and neck squamous cell carcinoma. Clin Cancer Res 2009; 15: 2850-2855.
26. Avissar M, McClean MD, Kelsey KT, Marsit CJ,. MicroRNA expression in head and neck cancer associates with alcohol consumption and survival. Carcinogenesis 2009; 30: 2059-2063.
27. Christensen BC, Moyer BJ, Avissar M, et al. A let-7 microRNA-binding site polymorphism in the KRAS 3â UTR is associated with reduced survival in oral cancers. Carcinogenesis 2009; 30: 1003-1007.
28. Hathaway B, Landsittel DP, Gooding W, et al. Multiplexed analysis of serum cytokines as biomarkers in squamous cell carcinoma of the head and neck patients. Laryngoscope 2005; 115: 522-527.
29. Linkov F, Lisovich A, Yurkovetsky Z, et al. Early detection of head and neck cancer: development of a novel screening tool using multiplexed immunobead-based biomarker profiling. Cancer Epidemiol Biomarkers Prev 2007; 16: 102-107.
30. Franzmann EJ, Reategui EP, Carraway KL, Hamilton KL, Weed DT, Goodwin WJ,. Salivary soluble CD44: a potential molecular marker for head and neck cancer. Cancer Epidemiol Biomarkers Prev 2005; 14: 735-739.
31. Franzmann EJ, Reategui EP, Pedroso F, et al. Soluble CD44 is a potential marker for the early detection of head and neck cancer. Cancer Epidemiol Biomarkers Prev 2007; 16: 1348-1355.
32. Smith TR, Levine EA, Freimanis RI, et al. Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. Carcinogenesis 2008; 29: 2132-2138.
33. Blot WJ, McLaughlin JK, Winn DM, et al. Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res 1988; 48: 3282-3287.
34. Schlecht NF, Franco EL, Pintos J, Kowalski LP,. Effect of smoking cessation and tobacco type on the risk of cancers of the upper aero-digestive tract in Brazil. Epidemiology 1999; 10: 412-418.
35. La Vecchia C, Franceschi S, Bosetti C, Levi F, Talamini R, Negri E,. Time since stopping smoking and the risk of oral and pharyngeal cancers. J Natl Cancer Inst 1999; 91: 726-728.
36. Smith IM, Mydlarz WK, Mithani SK, Califano JA,. DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage. Int J Cancer 2007; 121: 1724-1728.
37. Shpitzer T, Bahar G, Feinmesser R, Nagler RM,. A comprehensive salivary analysis for oral cancer diagnosis. J Cancer Res Clin Oncol 2007; 133: 613-617.
38. Arellano M, Jiang J, Zhou X, et al. Current advances in identification of cancer biomarkers in saliva. Front Biosci (Schol Ed) 2009; 1: 296-303.
39. Hashibe M, Brennan P, Benhamou S, et al. Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. J Natl Cancer Inst 2007; 99: 777-789.
40. Guha N, Boffetta P, Wünsch Filho V, et al. Oral health and risk of squamous cell carcinoma of the head and neck and esophagus: results of two multicentric case-control studies. Am J Epidemiol 2007; 166: 1159-1173.
41. Bánõczy J, Gintner Z, Dombi C,. Tobacco use and oral leukoplakia. J Dent Educ 2001; 65: 322-327.