The anti-tumor efficiency of poly(L-glutamic acid) dendrimers with polyhedral oligomeric silsesquioxane cores

Biomaterials

Volumn 34, Issue 14, 2013, Pages 3658-3666

  Pu, Yuji ^a   Chang, Shuang ^a   Yuan, Hui ^a   Wang, Gang ^a   He, Bin ^a   Gu, Zhongwei ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Dendrimer; Drug delivery; Nanoparticle; PH sensitive; Targeting

Indexed keywords

BREAST CANCER MODELS; IN-VIVO EXPERIMENTS; INHIBITION EFFICIENCY; PEPTIDE DENDRIMERS; PH SENSITIVE; POLY (LGLUTAMIC ACID); POLYHEDRAL OLIGOMERIC SILSESQUIOXANES; TARGETING;

AMINO ACIDS; BIOCOMPATIBILITY; DENDRIMERS; DISEASES; DRUG DELIVERY; MAMMALS; NANOPARTICLES; OLIGOMERS;

FUNCTIONAL POLYMERS;

BIOTIN; DENDRIMER; DOXORUBICIN; HYDRAZONE DERIVATIVE; NANOPARTICLE; OLIGOMER; POLYGLUTAMIC ACID; SILSESQUIOXANE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC FORCE MICROSCOPY; BREAST CANCER; CHEMICAL BOND; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; IC 50; LIGHT SCATTERING; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DENDRIMERS; DOXORUBICIN; DRUG CARRIERS; FEMALE; HYDROGEN-ION CONCENTRATION; MALE; MICE; MICE, INBRED BALB C; ORGANOSILICON COMPOUNDS; POLYGLUTAMIC ACID;

MUS;

EID: 84875258437     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.01.082     Document Type: Article

References (42)

1. Newkome G.R., Moorefield C.N., Vögtle F. Dendritic molecules: concepts, synthesis, perspectives 1996, VCH, Weinheim. Germany.
2. Crespo L., Sanclimens G., Pons M., Giralt E., Royo M., Albericio F. Peptide and amide bond-containing dendrimers. Chem Rev 2005, 105:1663-1682.
3. Gu Z.W., Luo K., She W.C., Wu Y., He B. New-generation biomedical materials: peptide dendrimers and their application in biomedicine. Sci China Chem 2010, 53:458-478.
4. Kobayashi H., Brechbiel M.W. Nano-sized MRI contrast agents with dendrimer cores. Adv Drug Deliv Rev 2005, 57:2271-2286.
5. Luo K., Liu G., He B., Wu Y., Gong Q., Song B., et al. Multifunctional gadolinium-based dendritic macromolecules as liver targeting imaging probes. Biomaterials 2011, 32:2575-2585.
6. Gillies E.R., Frechet J.M.J. Dendrimers and dendritic polymers in drug delivery. Drug Discov Today 2005, 10:35-43.
7. Medina S.H., El-Sayed M.E. Dendrimers as carriers for delivery of chemotherapeutic agents. Chem Rev 2009, 109:3141-3157.
8. Luo K., Li C., Li L., She W., Wang G., Gu Z. Arginine functionalized peptide dendrimers as potential gene delivery vehicles. Biomaterials 2012, 33:4917-4927.
9. Luo K., Li C., Wang G., Nie Y., He B., Wu Y., et al. Peptide dendrimers as efficient and biocompatible gene delivery vectors: synthesis and in vitro characterization. J Control Release 2011, 155:77-87.
10. Hu J., Su Y., Zhang H., Xu T., Cheng Y. Design of interior-functionalized fully acetylated dendrimers for anticancer drug delivery. Biomaterials 2011, 32:9950-9959.
11. Wang Y., Guo R., Cao X., Shen M., Shi X. Encapsulation of 2-methoxyestradiol within multifunctional poly(amidoamine) dendrimers for targeted cancer therapy. Biomaterials 2011, 32:3322-3329.
12. Kaminskas L.M., McLeod V.M., Porter C.J.H., Boyd B.J. Association of chemotherapeutic drugs with dendrimer nanocarriers: an assessment of the merits of covalent conjugation compared to noncovalent encapsulation. Mol Pharm 2012, 9:355-373.
13. Kojima C. Design of stimuli-responsive dendrimers. Expert Opin Drug Deliv 2010, 7:307-319.
14. Tannock I.F., Rotin D. Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res 1989, 49:4373-4384.
15. Gillies E.R., Jonsson T.B., Fréchet J.M.J. Stimuli-responsive supramolecular assemblies of linear-dendritic copolymers. J Am Chem Soc 2004, 126:11936-11943.
16. Prabaharan M., Grailer J.J., Pilla S., Steeber D.A., Gong S. Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery. Biomaterials 2009, 30:5757-5766.
17. Maeda H., Wu J., Sawa T., Matsumura Y., Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release 2000, 65:271-284.
18. Tanaka T., Shiramoto S., Miyashita M., Fujishima Y., Kaneo Y. Tumor targeting based on the effect of enhanced permeability and retention (EPR) and the mechanism of receptor-mediated endocytosis (RME). Int J Pharm 2004, 277:39-61.
19. Chandrasekar D., Sistla R., Ahmad F.J., Khar R.K., Diwan P.V. The development of folate-PAMAM dendrimer conjugates for targeted delivery of anti-arthritic drugs and their pharmacokinetics and biodistribution in arthritic rats. Biomaterials 2007, 28:504-512.
20. Kaneshiro T.L., Lu Z.R. Targeted intracellular codelivery of chemotherapeutics and nucleic acid with a well-defined dendrimer-based nanoglobular carrier. Biomaterials 2009, 30:5660-5666.
21. Remy J.S., Kichler A., Mordvinov V., Schuber F., Behr J.P. Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses. Proc Natl Acad Sci U S A 1995, 92:1744-1748.
22. Yang W., Cheng Y., Xu T., Wang X., Wen L. Targeting cancer cells with biotin-dendrimer conjugates. Eur J Med Chem 2009, 44:862-868.
23. Yellepeddi V.K., Kumar A., Palakurthi S. Biotinylated poly (amido) amine (PAMAM) dendrimers as carriers for drug delivery to ovarian cancer cells in vitro. Anticancer Res 2009, 29:2933-2943.
24. Su J., Chen F., Cryns V.L., Messersmith P.B. Catechol polymers for pH-responsive, targeted drug delivery to cancer cells. J Am Chem Soc 2011, 133:11850-11853.
25. Patil Y.B., Swaminathan S.K., Sadhukha T., Ma L., Panyam J. The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance. Biomaterials 2010, 31:358-365.
26. Heo D.N., Yang D.H., Moon H.J., Lee J.B., Bae M.S., Lee S.C., et al. Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy. Biomaterials 2012, 33:856-866.
27. Singh B., Florence A.T. Hydrophobic dendrimer-derived nanoparticles. Int J Pharm 2005, 298:348-353.
28. Zhang J., Hu J., Feng X., Li Y., Zhao L., Xu T., et al. Interactions between oppositely charged dendrimers. Soft Matter 2012, 8:9800-9806.
29. Jasmine M.J., Prasad E. Fractal growth of PAMAM dendrimer aggregates and its impact on the intrinsic emission properties. J Phys Chem B 2010, 114:7735-7742.
30. Ikeda M., Momotake A., Kanna Y., Shimotori K., Arai T. Self-assembly of a poly (glutamate) dendrimer: solvent-dependent expression of molecular chirality and a [2+2] photocrosslinking reaction. Photochem Photobiol Sci 2012, 11:1524-1527.
31. Feher F.J., Wyndham K.D., Soulivong D., Nguyen F. Syntheses of highly functionalized cube-octameric polyhedral oligosilsesquioxanes (R8Si8O12). J Chem Soc Dalton Trans 1999, 1491-1498.
32. Chandran S.S., Nan A., Rosen D.M., Ghandehari H., Denmeade S.R. A prostate-specific antigen-activated N-(2-hydroxypropyl) methacrylamide copolymer prodrug as dual-targeted therapy for prostate cancer. Mol Cancer Ther 2007, 6:2928-2937.
33. Sethuraman V.A., Bae Y.H. TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors. J Control Release 2007, 118:216-224.
34. Yuan H., Luo K., Lai Y., Pu Y., He B., Wang G., et al. A novel poly (L-glutamic acid) dendrimer based drug delivery system with both pH-sensitive and targeting functions. Mol Pharm 2010, 7:953-962.
35. Zhan F., Chen W., Wang Z., Lu W., Cheng R., Deng C., et al. Acid-activatable prodrug nanogels for efficient intracellular doxorubicin release. Biomacromolecules 2011, 12:3612-3620.
36. Yoo H.S., Park T.G. Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate. J Control Release 2004, 100:247-256.
37. Alani A.W.G., Bae Y., Rao D.A., Kwon G.S. Polymeric micelles for the pH-dependent controlled, continuous low dose release of paclitaxel. Biomaterials 2010, 31:1765-1772.
38. Bredihhin A., Mäeorg U. Effective strategy for the systematic synthesis of hydrazine derivatives. Tetrahedron 2008, 64:6788-6793.
39. Green N.M. Spectrophotometric determination of avidin and biotin. Methods Enzymol 1970, 18A:418-424.
40. Wanga X., Wu G., Lu C., Zhao W., Wang Y., Fan Y., et al. A novel delivery system of Doxorubicin with high load and pH-responsive release from the nanoparticles of poly (α, β-aspartic acid) derivative. Eur J Pharm Sci 2012, 47:256-264.
41. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983, 65:55-63.
42. Menon C., Polin G.M., Prabakaran I., Hsi A., Cheung C., Culver J.P., et al. An integrated approach to measuring tumor oxygen status using human melanoma xenografts as a model. Cancer Res 2003, 63:7232-7240.