Cryopreserved deglycerolized blood is safe and achieves superior tissue oxygenation compared with refrigerated red blood cells: A prospective randomized pilot study

Journal of Trauma and Acute Care Surgery

Volumn 74, Issue 2, 2013, Pages 371-377

  Fabricant, Loic ^a   Kiraly, Laszlo ^a   Wiles, Connor ^a   Differding, Jerome ^a   Underwood, Samantha ^a   Deloughery, Thomas ^a   Schreiber, Martin ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Oxygenation; Red blood cells; Storage; Transfusion

Indexed keywords

ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; BLOOD STORAGE; BLOOD TRANSFUSION REACTION; CONTROLLED STUDY; CRYOPRESERVATION; DEEP VEIN THROMBOSIS; ERYTHROCYTE; ERYTHROCYTE PRESERVATION; ERYTHROCYTE TRANSFUSION; FEMALE; FEVER; HEMATOCRIT; HUMAN; HUMAN CELL; HUMAN TISSUE; INJURY SCALE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIPLE ORGAN FAILURE; OUTCOME ASSESSMENT; PILOT STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY FAILURE; THROMBOELASTOGRAPHY; TISSUE OXYGENATION;

ADULT; AGED; BLOOD PRESERVATION; COLD TEMPERATURE; CRYOPRESERVATION; DOUBLE-BLIND METHOD; ERYTHROCYTE TRANSFUSION; FEMALE; HEMATOCRIT; HUMANS; INJURY SEVERITY SCORE; MALE; MIDDLE AGED; PILOT PROJECTS; PROSPECTIVE STUDIES; THROMBELASTOGRAPHY; TREATMENT OUTCOME; WOUNDS AND INJURIES;

EID: 84875237781     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e31827e1d40     Document Type: Article

References (37)

1. Shapiro MJ, Gettinger A, Corwin HL. Anemia and blood transfusion in trauma patients admitted to the intensive care unit. J Trauma. 2003;55: 269-273.
2. Scharte M, Fink MP. Red blood cell physiology in critical illness. Crit Care Med. 2003;31(Suppl 12):S651-S657.
3. Sakr Y, Chierego M, Piagnerelli M, et al. Microvascular response to red blood cell transfusion in patients with severe sepsis. Crit Care Med. 2007;35:1639-1644.
4. Santos MT, Valles J, Marcus AJ, et al. Enhancement of platelet reactivity and modulation of eicosanoid production by intact erythrocytes. A new approach to platelet activation and recruitment. J Clin Invest. 1991;87: 571-580.
5. Corwin HL, Gettinger A, Pearl RG, et al. The CRIT study: anemia and blood transfusion in the critically illVcurrent clinical practice in the united states. Crit Care Med. 2004;32:39-52.
6. ABC blood supply status report. Northumberland, UK: ABC Publications; 2006 (updated 2007). Available at: http://www.americasblood.org. Accessed May 21, 2009.
7. Wolfe LC. The membrane and the lesions of storage in preserved red cells. Transfusion. 1985;25:185-203.
8. Smith AU. Prevention of haemolysis during freezing and thawing of red blood-cells. Lancet. 1950;2:910-911.
9. Mollison PL, Sloviter HA. Successful transfusion of previously frozen human red cells. Lancet. 1951;2:862-864.
10. Meryman HT, Hornblower M. A method for freezing and washing red blood cells using a high glycerol concentration. Transfusion. 1972;12:145-156.
11. Hess JH, Greenwalt TJ. Storage of red blood cells: New approaches. Transfus Med Rev. 2002;16:283-295.
12. Valeri CR, Ragno G, Pivacek LE, et al. Anexperiment with glycerol-frozen red blood cells stored at j80 degrees C for up to 37 years. Vox Sang. 2000;79:168-174.
13. Valeri CR, Brodine CE. Current methods for processing frozen red cells. Cryobiology. 1968;5:129-135.
14. Valeri CR, Pivacek LE, Cassidy GP, Ragno G. Posttransfusion survival (24-hour) and hemolysis of previously frozen, deglycerolized RBCs after storage at 4-C for up to 14 days in sodium chloride alone or sodium chloride supplemented with additive solutions. Transfusion. 2000;40: 1337-1340.
15. Telischi M, Hoiberg R, Rao KR, Patel AR. The use of frozen, thawed erythrocytes in blood banking: a report of 28 months' experience in a large transfusion service. Am J Clin Pathol. 1977;68:250-257.
16. Tullis JL, Haynes LL, Pyle HM, et al. Clinical use of frozen red cells. Arch Surg. 1960;81:151-154.
17. Hess JH. Red cell freezing and its impact on the supply chain. Transfus Med. 2004;14:1-8.
18. Cohn SM, Nathens AB, Moore FA, et al. Tissue oxygen saturation predicts the development of organ dysfunction during traumatic shock resuscitation. J Trauma. 2007;62:44-54; discussion 54-55.
19. Rogers MA, Levine DA, Blumberg N, Flanders S, Chopra V, Langa KM. Triggers of hospitalization for venous thromboembolism. Circulation. Available at: www://circ.ahajournals.org. Accessed August 15, 2012.
20. Bernard GR, Artigas A, Brigham KL, et al. The American-European consensus conference on ARDS. definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med. 1994;149(3 Pt 1):818-824.
21. Moore FA, Sauaia A, Moore EE, Haenel JB, Burch JM, Lezotte DC. Postinjury multiple organ failure: a bimodal phenomenon. J Trauma. 1996; 40:501-510.
22. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute renal failureVdefinition, outcome measures, animal models, fluid therapy and information technology needs: the second international consensus conference of the acute dialysis quality initiative (ADQI) group. Crit Care. 2004;8:R204-R212.
23. Moerman A, Wouters P. Near-infrared spectroscopy (NIRS) monitoring in contemporary anesthesia and critical care. Acta Anaesthesiol Belg. 2010; 61:185-194.
24. Terborg C, Groschel K, Petrovitch A. Noninvasive assessment of cerebral perfusion and oxygenation in acute ischemic stroke by near-infrared spectroscopy. Eur Neurol. 2009;62:338-343.
25. Shuler MS, Reisman WM, Kinsey TL. Correlation between muscle oxy-genation and compartment pressures in acute compartment syndrome of the leg. J Bone Joint Surg Am. 2010;92:863-870.
26. Kiraly LN, Underwood S, Differding JA, Schreiber, MA. Transfusion of aged packed red blood cells results in decreased tissue oxygenation in critically injured trauma patients. J Trauma. 2009;67:29-32.
27. Singel DJ, Stamler JS. Chemical physiology of blood flow regulation by red blood cells: The role of nitric oxide and S-nitrosohemoglobin. Annu Rev Physiol. 2005;67:99-145.
28. Reynolds JD, Ahearn GS, Angelo M, Zhang J, Cobb F, Stamler JS. S-nitrosohemoglobin deficiency: a mechanism for loss of physiological activity in banked blood. Proc Natl Acad Sci USA. 2007;104:17058-17062.
29. Hsia CC. Respiratory function of hemoglobin. N Engl J Med. 1998;338: 239-247.
30. Raat NJ, Ince C. Oxygenating the microcirculation: The perspective from blood transfusion and blood storage. Vox Sang. 2007;93:12-18.
31. O'Brien TG, Watkins E. Gas-exchange dynamics of glycerolized frozen blood. J Thorac Cardiovasc Surg. 1960;40:611-624.
32. Relevy H, Koshkaryev A, Manny N, Yedgar S, Barshtein G. Blood banking-induced alteration of red blood cell flow properties. Transfusion. 2008;48:136-146.
33. Warkentin TE, Barr RD, Ali MANM. Recurrent acute splenic sequestration crisis due to interacting genetic defects: hemoglobin SC disease and hereditary spherocytosis. Blood. 1990;75:266-270.
34. Arun P, Padmakumaran Nair KG, Manojkumar V, Deepadevi KV, Lakshmi LR, Kurup PA. Decreased hemolysis and lipid peroxidation in blood during storage in the presence of nicotinic acid. Vox Sang. 1999;76:220-225.
35. Lecak J, Scott K, Young C, Hannon J, Acker JP. Evaluation of red blood cells stored at j80 degrees C in excess of 10 years. Transfusion. 2004;44:1306-1313.
36. Valeri CR. Status report on the quality of liquid and frozen red blood cells. Vox Sang. 2002;83(Suppl 1):193-196.
37. Whitaker BI, Green J, King M, et al. The 2007 national blood collection and utilization survey report. Bethesda, MD: AABB and US Department of Health and Human Services; 2007. Available at: http://www.hhs.gov/ophs/bloodsafety/ 2007nbcus-survey.pdf. Accessed May 21, 2009.