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Volumn 432, Issue 2, 2013, Pages 320-325

Fenofibrate down-regulates the expressions of androgen receptor (AR) and AR target genes and induces oxidative stress in the prostate cancer cell line LNCaP

Author keywords

Androgen receptor; Fenofibrate; LNCaP; Oxidative stress

Indexed keywords

ANDROGEN RECEPTOR; FENOFIBRATE; MALONALDEHYDE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

EID: 84875232583     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.01.105     Document Type: Article
Times cited : (30)

References (22)
  • 2
    • 0030939099 scopus 로고    scopus 로고
    • Hormonal therapy in the management of prostate cancer: from Huggins to the present
    • Garnick M.B. Hormonal therapy in the management of prostate cancer: from Huggins to the present. Urology 1997, 49:5-15.
    • (1997) Urology , vol.49 , pp. 5-15
    • Garnick, M.B.1
  • 4
    • 24744471465 scopus 로고    scopus 로고
    • Regulation of androgen receptor levels: implications for prostate cancer progression and therapy
    • Burnstein K.L. Regulation of androgen receptor levels: implications for prostate cancer progression and therapy. J. Cell. Biochem. 2005, 95:657-669.
    • (2005) J. Cell. Biochem. , vol.95 , pp. 657-669
    • Burnstein, K.L.1
  • 5
    • 36849007390 scopus 로고    scopus 로고
    • Androgen signaling and its interactions with other signaling pathways in prostate cancer
    • Kaarbo M., Klokk T.I., Saatcioglu F. Androgen signaling and its interactions with other signaling pathways in prostate cancer. Bioessays 2007, 29:1227-1238.
    • (2007) Bioessays , vol.29 , pp. 1227-1238
    • Kaarbo, M.1    Klokk, T.I.2    Saatcioglu, F.3
  • 6
    • 14244254699 scopus 로고    scopus 로고
    • Regulation of androgen receptor signaling in prostate cancer
    • Dehm S.M., Tindall D.J. Regulation of androgen receptor signaling in prostate cancer. Expert Rev. Anticancer Ther. 2005, 5:63-74.
    • (2005) Expert Rev. Anticancer Ther. , vol.5 , pp. 63-74
    • Dehm, S.M.1    Tindall, D.J.2
  • 8
    • 77953657756 scopus 로고    scopus 로고
    • ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro
    • Drukala J., Urbanska K., Wilk A., Grabacka M., Wybieralska E., Del Valle L., Madeja Z., Reiss K. ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro. Mol. Cancer 2010, 9:159.
    • (2010) Mol. Cancer , vol.9 , pp. 159
    • Drukala, J.1    Urbanska, K.2    Wilk, A.3    Grabacka, M.4    Wybieralska, E.5    Del Valle, L.6    Madeja, Z.7    Reiss, K.8
  • 9
    • 0036123602 scopus 로고    scopus 로고
    • Effects of dehydroepiandrosterone on rat apolipoprotein AI gene expression in the human hepatoma cell line, HepG2
    • Deleon M.J., Horani M.H., Haas M.J., Wong N.C., Mooradian A.D. Effects of dehydroepiandrosterone on rat apolipoprotein AI gene expression in the human hepatoma cell line, HepG2. Metabolism 2002, 51:376-379.
    • (2002) Metabolism , vol.51 , pp. 376-379
    • Deleon, M.J.1    Horani, M.H.2    Haas, M.J.3    Wong, N.C.4    Mooradian, A.D.5
  • 10
    • 33745103705 scopus 로고    scopus 로고
    • In vitro and in vivo effects of the PPAR-alpha agonists fenofibrate and retinoic acid in endometrial cancer
    • Saidi S.A., Holland C.M., Charnock-Jones D.S., Smith S.K. In vitro and in vivo effects of the PPAR-alpha agonists fenofibrate and retinoic acid in endometrial cancer. Mol. Cancer 2006, 5:13.
    • (2006) Mol. Cancer , vol.5 , pp. 13
    • Saidi, S.A.1    Holland, C.M.2    Charnock-Jones, D.S.3    Smith, S.K.4
  • 11
    • 56249138279 scopus 로고    scopus 로고
    • Curcumin blocks the activation of androgen and interlukin-6 on prostate-specific antigen expression in human prostatic carcinoma cells
    • Tsui K.H., Feng T.H., Lin C.M., Chang P.L., Juang H.H. Curcumin blocks the activation of androgen and interlukin-6 on prostate-specific antigen expression in human prostatic carcinoma cells. J. Androl. 2008, 29:661-668.
    • (2008) J. Androl. , vol.29 , pp. 661-668
    • Tsui, K.H.1    Feng, T.H.2    Lin, C.M.3    Chang, P.L.4    Juang, H.H.5
  • 12
    • 33746538284 scopus 로고    scopus 로고
    • Regulatory processes affecting androgen receptor expression, stability, and function: potential targets to treat hormone-refractory prostate cancer
    • Reddy G.P., Barrack E.R., Dou Q.P., Menon M., Pelley R., Sarkar F.H., Sheng S. Regulatory processes affecting androgen receptor expression, stability, and function: potential targets to treat hormone-refractory prostate cancer. J. Cell. Biochem. 2006, 98:1408-1423.
    • (2006) J. Cell. Biochem. , vol.98 , pp. 1408-1423
    • Reddy, G.P.1    Barrack, E.R.2    Dou, Q.P.3    Menon, M.4    Pelley, R.5    Sarkar, F.H.6    Sheng, S.7
  • 13
    • 77957188666 scopus 로고
    • Fenofibrate: metabolism and species differences for peroxisome proliferation in cultured hepatocytes
    • Cornu-Chagnon M.C., Dupont H., Edgar A. Fenofibrate: metabolism and species differences for peroxisome proliferation in cultured hepatocytes. Fundam. Appl. Toxicol. 1995, 26:63-74.
    • (1995) Fundam. Appl. Toxicol. , vol.26 , pp. 63-74
    • Cornu-Chagnon, M.C.1    Dupont, H.2    Edgar, A.3
  • 16
    • 0036087028 scopus 로고    scopus 로고
    • Role of Bcl-2 family of proteins in malignancy
    • Baliga B.C., Kumar S. Role of Bcl-2 family of proteins in malignancy. Hematol. Oncol. 2002, 20:63-74.
    • (2002) Hematol. Oncol. , vol.20 , pp. 63-74
    • Baliga, B.C.1    Kumar, S.2
  • 17
    • 0033604585 scopus 로고    scopus 로고
    • The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB
    • Kandel E.S., Hay N. The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp. Cell Res. 1999, 253:210-229.
    • (1999) Exp. Cell Res. , vol.253 , pp. 210-229
    • Kandel, E.S.1    Hay, N.2
  • 20
    • 84855293853 scopus 로고    scopus 로고
    • Protective Effects of Peroxisome Proliferator-Activated Receptor-alpha Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes
    • Chen K., Li Y.H., Xu S.Q., Hu S.H., Zhang L. Protective Effects of Peroxisome Proliferator-Activated Receptor-alpha Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes. PPAR Res. 2012, 2012:547980.
    • (2012) PPAR Res. , vol.2012 , pp. 547980
    • Chen, K.1    Li, Y.H.2    Xu, S.Q.3    Hu, S.H.4    Zhang, L.5
  • 22
    • 0032411042 scopus 로고    scopus 로고
    • Roles of reactive oxygen species: signaling and regulation of cellular functions
    • Gamaley I.A., Klyubin I.V. Roles of reactive oxygen species: signaling and regulation of cellular functions. Int. Rev. Cytol. 1999, 188:203-255.
    • (1999) Int. Rev. Cytol. , vol.188 , pp. 203-255
    • Gamaley, I.A.1    Klyubin, I.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.