3-Methoxyapigenin modulates β-catenin stability and inhibits Wnt/β-catenin signaling in Jurkat leukemic cells

Life Sciences

Volumn 92, Issue 12, 2013, Pages 677-686

  Chuang, Kai An ^a   Lieu, Chien Hui ^a   Tsai, Wei Jern ^a,b   Huang, Wen Hsin ^c   Lee, An Rong ^c   Kuo, Yuh Chi ^d  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^d FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

catenin; Anti cancer; Glycogen synthase kinase 3 (GSK 3 ); Leukemia; Wnt

Indexed keywords

3 METHOXYAPIGENIN; APIGENIN; BETA CATENIN; CASEIN KINASE II; CYCLIN D3; GLYCOGEN SYNTHASE KINASE 3BETA; MYC PROTEIN; PLANT EXTRACT; THYMIDINE; UNCLASSIFIED DRUG; WNT PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG ISOLATION; ENZYME INHIBITION; GENE TARGETING; GENE TRANSLOCATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION; WESTERN BLOTTING;

ANTHOCYANINS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APIGENIN; BETA CATENIN; CASEIN KINASE II; CELL PROLIFERATION; CYCLIN D3; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, MYC; GLYCOGEN SYNTHASE KINASE 3; HEK293 CELLS; HUMANS; JURKAT CELLS; LEUKEMIA, T-CELL; PROTEIN STABILITY; PROTEIN TRANSPORT; WNT PROTEINS; WNT SIGNALING PATHWAY; ZINGIBERACEAE;

EID: 84875231878     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.12.007     Document Type: Article

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