메뉴 건너뛰기




Volumn 108, Issue 3, 2013, Pages 557-563

Regulation of tamoxifen sensitivity by a PAK1-EBP1 signalling pathway in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; LETROZOLE; P21 ACTIVATED KINASE 1; SHORT HAIRPIN RNA; TAMOXIFEN;

EID: 84875230023     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2013.11     Document Type: Article
Times cited : (18)

References (32)
  • 1
    • 33646759590 scopus 로고    scopus 로고
    • Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase
    • Ahn JY, Liu X, Liu Z, Pereira L, Cheng D, Peng J, Wade PA, Hamburger AW, Ye K (2006) Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase. EMBO J 25: 2083-2095.
    • (2006) EMBO J , vol.25 , pp. 2083-2095
    • Ahn, J.Y.1    Liu, X.2    Liu, Z.3    Pereira, L.4    Cheng, D.5    Peng, J.6    Wade, P.A.7    Hamburger, A.W.8    Ye, K.9
  • 2
    • 40849135855 scopus 로고    scopus 로고
    • Phosphorylation of the ErbB3 binding protein Ebp1 by p21-activated kinase 1 in breast cancer cells
    • Akinmade D, Talukder AH, Zhang Y, Luo WM, Kumar R, Hamburger AW (2008) Phosphorylation of the ErbB3 binding protein Ebp1 by p21-activated kinase 1 in breast cancer cells. Br J Cancer 98: 1132-1140.
    • (2008) Br J Cancer , vol.98 , pp. 1132-1140
    • Akinmade, D.1    Talukder, A.H.2    Zhang, Y.3    Luo, W.M.4    Kumar, R.5    Hamburger, A.W.6
  • 3
    • 0346462998 scopus 로고    scopus 로고
    • P21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells
    • Balasenthil S, SahinAA, BarnesCJ, Wang RA, Pestell RG,Vadlamudi RK, Kumar R (2004) p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells. J Biol Chem 279: 1422-1428.
    • (2004) J Biol Chem , vol.279 , pp. 1422-1428
    • Balasenthil, S.1    Barnescj, S.2    Wang, R.A.3    Pestell Rgvadlamudi, R.K.4    Kumar, R.5
  • 4
    • 35549002845 scopus 로고    scopus 로고
    • Amplification of CCND1 and PAK1 as predictors of recurrence and tamoxifen resistance in postmenopausal breast cancer
    • Bostner J, Ahnstrom WM, Fornander T, Skoog L, Nordenskjold B, Stal O (2007) Amplification of CCND1 and PAK1 as predictors of recurrence and tamoxifen resistance in postmenopausal breast cancer. Oncogene 26: 6997-7005.
    • (2007) Oncogene , vol.26 , pp. 6997-7005
    • Bostner, J.1    Ahnstrom, W.M.2    Fornander, T.3    Skoog, L.4    Nordenskjold, B.5    Stal, O.6
  • 5
    • 77649091619 scopus 로고    scopus 로고
    • Estrogen receptor-alpha phosphorylation at serine 305, nuclear p21-activated kinase 1 expression, and response to tamoxifen in postmenopausal breast cancer
    • Bostner J, Skoog L, Fornander T, Nordenskjold B, Stal O (2010) Estrogen receptor-alpha phosphorylation at serine 305, nuclear p21-activated kinase 1 expression, and response to tamoxifen in postmenopausal breast cancer. Clin Cancer Res 16: 1624-1633.
    • (2010) Clin Cancer Res , vol.16 , pp. 1624-1633
    • Bostner, J.1    Skoog, L.2    Fornander, T.3    Nordenskjold, B.4    Stal, O.5
  • 6
    • 0035101145 scopus 로고    scopus 로고
    • Cellular and molecular pharmacology of antiestrogen action and resistance
    • Clarke R, Leonessa F, Welch JN, Skaar TC (2001) Cellular and molecular pharmacology of antiestrogen action and resistance. Pharmacol Rev 53: 25-71.
    • (2001) Pharmacol Rev , vol.53 , pp. 25-71
    • Clarke, R.1    Leonessa, F.2    Welch, J.N.3    Skaar, T.C.4
  • 7
    • 41949100602 scopus 로고    scopus 로고
    • An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase
    • Deacon SW, Beeser A, Fukui JA, Rennefahrt UE, Myers C, Chernoff J, Peterson JR (2008) An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem Biol 15: 322-331.
    • (2008) Chem Biol , vol.15 , pp. 322-331
    • Deacon, S.W.1    Beeser, A.2    Fukui, J.A.3    Rennefahrt, U.E.4    Myers, C.5    Chernoff, J.6    Peterson, J.R.7
  • 9
    • 33646940460 scopus 로고    scopus 로고
    • Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients
    • Holm C, Rayala S, Jirstrom K, Stal O, Kumar R, Landberg G (2006) Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients. J Natl Cancer Inst 98: 671-680.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 671-680
    • Holm, C.1    Rayala, S.2    Jirstrom, K.3    Stal, O.4    Kumar, R.5    Landberg, G.6
  • 10
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes NE, Lane HA (2005) ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 5: 341-354.
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 11
    • 20644465808 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase in xenografts and cells during prolonged treatment with aromatase inhibitor letrozole
    • Jelovac D, Sabnis G, Long BJ, Macedo L, Goloubeva OG, Brodie AM (2005) Activation of mitogen-activated protein kinase in xenografts and cells during prolonged treatment with aromatase inhibitor letrozole. Cancer Res 65: 5380-5389.
    • (2005) Cancer Res , vol.65 , pp. 5380-5389
    • Jelovac, D.1    Sabnis, G.2    Long, B.J.3    MacEdo, L.4    Goloubeva, O.G.5    Brodie, A.M.6
  • 13
    • 0034667395 scopus 로고    scopus 로고
    • Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells
    • Kurokawa H, Lenferink AE, Simpson JF, Pisacane PI, SliwkowskiMX, Forbes JT, Arteaga CL (2000) Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells. Cancer Res 60: 5887-5894.
    • (2000) Cancer Res , vol.60 , pp. 5887-5894
    • Kurokawa, H.1    Lenferink, A.E.2    Simpson, J.F.3    Pisacane, P.I.4    Sliwkowski, M.X.5    Forbes, J.T.6    Arteaga, C.L.7
  • 14
    • 0034054236 scopus 로고    scopus 로고
    • Ectopic expression of the ErbB-3 binding protein ebp1 inhibits growth and induces differentiation of human breast cancer cell lines
    • Lessor TJ, Yoo JY, Xia X, Woodford N, Hamburger AW (2000) Ectopic expression of the ErbB-3 binding protein ebp1 inhibits growth and induces differentiation of human breast cancer cell lines. J Cell Physiol 183: 321-329.
    • (2000) J Cell Physiol , vol.183 , pp. 321-329
    • Lessor, T.J.1    Yoo, J.Y.2    Xia, X.3    Woodford, N.4    Hamburger, A.W.5
  • 15
    • 33746660688 scopus 로고    scopus 로고
    • Ebp1 isoforms distinctively regulate cell survival and differentiation
    • Liu Z, Ahn JY, Liu X, Ye K (2006) Ebp1 isoforms distinctively regulate cell survival and differentiation. Proc Natl Acad Sci USA 103: 10917-10922.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10917-10922
    • Liu, Z.1    Ahn, J.Y.2    Liu, X.3    Ye, K.4
  • 16
    • 79251519290 scopus 로고    scopus 로고
    • The ErbB3 binding protein EBP1 regulates ErbB2 protein levels and tamoxifen sensitivity in breast cancer cells
    • Lu Y, Zhou H, Chen W, Zhang Y, Hamburger AW (2011) The ErbB3 binding protein EBP1 regulates ErbB2 protein levels and tamoxifen sensitivity in breast cancer cells. Breast Cancer Res Treat 126: 27-36.
    • (2011) Breast Cancer Res Treat , vol.126 , pp. 27-36
    • Lu, Y.1    Zhou, H.2    Chen, W.3    Zhang, Y.4    Hamburger, A.W.5
  • 21
    • 32944473985 scopus 로고    scopus 로고
    • P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation
    • Rayala SK, Talukder AH, Balasenthil S, Tharakan R, Barnes CJ, Wang RA, Aldaz M, Khan S, Kumar R (2006) P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation. Cancer Res 66: 1694-1701.
    • (2006) Cancer Res , vol.66 , pp. 1694-1701
    • Rayala, S.K.1    Talukder, A.H.2    Balasenthil, S.3    Tharakan, R.4    Barnes, C.J.5    Wang, R.A.6    Aldaz, M.7    Khan, S.8    Kumar, R.9
  • 22
    • 60549089850 scopus 로고    scopus 로고
    • Trastuzumab reverses letrozole resistance and amplifies the sensitivity of breast cancer cells to estrogen
    • Sabnis G, Schayowitz A, Goloubeva O, Macedo L, Brodie A (2009) Trastuzumab reverses letrozole resistance and amplifies the sensitivity of breast cancer cells to estrogen. Cancer Res 69: 1416-1428.
    • (2009) Cancer Res , vol.69 , pp. 1416-1428
    • Sabnis, G.1    Schayowitz, A.2    Goloubeva, O.3    MacEdo, L.4    Brodie, A.5
  • 23
    • 2942652871 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen resistance: Increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer
    • Shou J, Massarweh S, Osborne CK, Wakeling AE, Ali S, Weiss H, Schiff R (2004) Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer. J Natl Cancer Inst 96(12): 926-935.
    • (2004) J Natl Cancer Inst , vol.96 , Issue.12 , pp. 926-935
    • Shou, J.1    Massarweh, S.2    Osborne, C.K.3    Wakeling, A.E.4    Ali, S.5    Weiss, H.6    Schiff, R.7
  • 25
    • 33646164893 scopus 로고    scopus 로고
    • Ebp1 is a dsRNA-binding protein associated with ribosomes that modulates eIF2alpha phosphorylation
    • Squatrito M, Mancino M, Sala L, Draetta GF (2006) Ebp1 is a dsRNA-binding protein associated with ribosomes that modulates eIF2alpha phosphorylation. Biochem Biophys Res Commun 344: 859-868.
    • (2006) Biochem Biophys Res Commun , vol.344 , pp. 859-868
    • Squatrito, M.1    Mancino, M.2    Sala, L.3    Draetta, G.F.4
  • 26
    • 0034680834 scopus 로고    scopus 로고
    • Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells
    • Vadlamudi RK, Adam L, Wang RA, Mandal M, Nguyen D, Sahin A, Chernoff J, Hung MC, Kumar R (2000) Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells. J Biol Chem 275: 36238-36244.
    • (2000) J Biol Chem , vol.275 , pp. 36238-36244
    • Vadlamudi, R.K.1    Adam, L.2    Wang, R.A.3    Mandal, M.4    Nguyen, D.5    Sahin, A.6    Chernoff, J.7    Hung, M.C.8    Kumar, R.9
  • 27
    • 70349484472 scopus 로고    scopus 로고
    • An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently
    • Viaud J, Peterson JR (2009) An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently. Mol Cancer Ther 8: 2559-2565.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2559-2565
    • Viaud, J.1    Peterson, J.R.2
  • 28
    • 0035059136 scopus 로고    scopus 로고
    • Ebp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulation
    • Xia X, Cheng A, Lessor T, Zhang Y, Hamburger AW (2001a) Ebp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulation. J Cell Physiol 187: 209-217.
    • (2001) J Cell Physiol , vol.187 , pp. 209-217
    • Xia, X.1    Cheng, A.2    Lessor, T.3    Zhang, Y.4    Hamburger, A.W.5
  • 31
    • 0037040291 scopus 로고    scopus 로고
    • Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1
    • Zang M, Hayne C, Luo Z (2002) Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1. J Biol Chem 277: 4395-4405.
    • (2002) J Biol Chem , vol.277 , pp. 4395-4405
    • Zang, M.1    Hayne, C.2    Luo, Z.3
  • 32
    • 44149094557 scopus 로고    scopus 로고
    • Inhibition of heregulin mediated MCF-7 breast cancer cell growth by the ErbB3 binding protein EBP1
    • Zhang Y, Akinmade D, Hamburger AW (2008) Inhibition of heregulin mediated MCF-7 breast cancer cell growth by the ErbB3 binding protein EBP1. Cancer Lett 265: 298-306.
    • (2008) Cancer Lett , vol.265 , pp. 298-306
    • Zhang, Y.1    Akinmade, D.2    Hamburger, A.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.