메뉴 건너뛰기




Volumn 98, Issue 6, 2008, Pages 1132-1140

Phosphorylation of the ErbB3 binding protein Ebp1 by p21-activated kinase 1 in breast cancer cells

Author keywords

Breast cancer; Ebp1; PA2G4; PAK1; Phosphorylation

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 3 BINDING PROTEIN 1; NEU DIFFERENTIATION FACTOR; P21 ACTIVATED KINASE 1; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 40849135855     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604261     Document Type: Article
Times cited : (23)

References (39)
  • 1
    • 0032561206 scopus 로고    scopus 로고
    • Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase
    • Adam L, Vadlamudi R, Kondapaka SB, Chernoff J, Mendelsohn J, Kumar R (1998) Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase. J Biol Chem 273: 28238-28246
    • (1998) J Biol Chem , vol.273 , pp. 28238-28246
    • Adam, L.1    Vadlamudi, R.2    Kondapaka, S.B.3    Chernoff, J.4    Mendelsohn, J.5    Kumar, R.6
  • 2
    • 33646759590 scopus 로고    scopus 로고
    • Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase
    • Ahn JY, Liu X, Liu Z, Pereira L, Cheng D, Peng J, Wade PA, Hamburger AW, Ye K (2006) Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase. EMBO J 25: 2083-2095
    • (2006) EMBO J , vol.25 , pp. 2083-2095
    • Ahn, J.Y.1    Liu, X.2    Liu, Z.3    Pereira, L.4    Cheng, D.5    Peng, J.6    Wade, P.A.7    Hamburger, A.W.8    Ye, K.9
  • 3
    • 35848940281 scopus 로고    scopus 로고
    • Ebp1-mediated inhibition of cell growth requires serine 363 phosphorylation
    • Akinmade D, Lee M, Zhang Y, Hamburger AW (2007) Ebp1-mediated inhibition of cell growth requires serine 363 phosphorylation. Int J Oncol 31: 851-858
    • (2007) Int J Oncol , vol.31 , pp. 851-858
    • Akinmade, D.1    Lee, M.2    Zhang, Y.3    Hamburger, A.W.4
  • 8
    • 0042307325 scopus 로고    scopus 로고
    • The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
    • Holbro T, Beerli RR, Maurer F, Koziczak M, Barbas III CF, Hynes NE (2003a) The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc Natl Acad Sci USA 100: 8933-8938
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8933-8938
    • Holbro, T.1    Beerli, R.R.2    Maurer, F.3    Koziczak, M.4    Barbas III, C.F.5    Hynes, N.E.6
  • 9
    • 0037429725 scopus 로고    scopus 로고
    • The ErbB receptors and their role in cancer progression
    • Holbro T, Civenni G, Hynes NE (2003b) The ErbB receptors and their role in cancer progression. Exp Cell Res 284: 99-110
    • (2003) Exp Cell Res , vol.284 , pp. 99-110
    • Holbro, T.1    Civenni, G.2    Hynes, N.E.3
  • 10
    • 33646940460 scopus 로고    scopus 로고
    • Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients
    • Holm C, Rayala S, Jirstrom K, Stal O, Kumar R, Landberg G (2006) Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients. J Natl Cancer Inst 98: 671-680
    • (2006) J Natl Cancer Inst , vol.98 , pp. 671-680
    • Holm, C.1    Rayala, S.2    Jirstrom, K.3    Stal, O.4    Kumar, R.5    Landberg, G.6
  • 11
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes NE, Lane HA (2005) ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 5: 341-354
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 12
    • 0345687908 scopus 로고    scopus 로고
    • Herstatin inhibits heregulin-mediated breast cancer cell growth and overcomes tamoxifen resistance in breast cancer cells that overexpress HER-2
    • Jhabvala-Romero F, Evans A, Guo S, Denton M, Clinton GM (2003) Herstatin inhibits heregulin-mediated breast cancer cell growth and overcomes tamoxifen resistance in breast cancer cells that overexpress HER-2. Oncogene 22: 8178-8186
    • (2003) Oncogene , vol.22 , pp. 8178-8186
    • Jhabvala-Romero, F.1    Evans, A.2    Guo, S.3    Denton, M.4    Clinton, G.M.5
  • 13
    • 0028364529 scopus 로고
    • Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression
    • Johnson DG, Ohtani K, Nevins JR (1994) Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev 8: 1514-1525
    • (1994) Genes Dev , vol.8 , pp. 1514-1525
    • Johnson, D.G.1    Ohtani, K.2    Nevins, J.R.3
  • 14
    • 32944466881 scopus 로고    scopus 로고
    • Clinical efforts to combine endocrine agents with targeted therapies against epidermal growth factor receptor/human epidermal growth factor receptor 2 and mammalian target of rapamycin in breast cancer
    • Johnston SR (2006) Clinical efforts to combine endocrine agents with targeted therapies against epidermal growth factor receptor/human epidermal growth factor receptor 2 and mammalian target of rapamycin in breast cancer. Clin Cancer Res 12: 1061s-1068s
    • (2006) Clin Cancer Res , vol.12
    • Johnston, S.R.1
  • 15
    • 0033782191 scopus 로고    scopus 로고
    • In vivo activity of wild-type and mutant PAKs
    • King CC, Sanders LC, Bokoch GM (2000) In vivo activity of wild-type and mutant PAKs. Methods Enzymol 325: 315-327
    • (2000) Methods Enzymol , vol.325 , pp. 315-327
    • King, C.C.1    Sanders, L.C.2    Bokoch, G.M.3
  • 16
    • 0024326947 scopus 로고
    • Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors
    • Kraus MH, Issing W, Miki T, Popescu NC, Aaronson SA (1989) Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc Natl Acad Sci USA 86: 9193-9197
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9193-9197
    • Kraus, M.H.1    Issing, W.2    Miki, T.3    Popescu, N.C.4    Aaronson, S.A.5
  • 18
    • 0036836941 scopus 로고    scopus 로고
    • Emerging functions of p21-activated kinases in human cancer cells
    • Kumar R, Vadlamudi RK (2002) Emerging functions of p21-activated kinases in human cancer cells. J Cell Physiol 193: 133-144
    • (2002) J Cell Physiol , vol.193 , pp. 133-144
    • Kumar, R.1    Vadlamudi, R.K.2
  • 20
    • 0035946549 scopus 로고    scopus 로고
    • Regulation of the ErbB3 binding protein Ebp1 by protein kinase C
    • Lessor TJ, Hamburger AW (2001) Regulation of the ErbB3 binding protein Ebp1 by protein kinase C. Mol Cell Endocrinol 175: 185-191
    • (2001) Mol Cell Endocrinol , vol.175 , pp. 185-191
    • Lessor, T.J.1    Hamburger, A.W.2
  • 21
    • 0034054236 scopus 로고    scopus 로고
    • Ectopic expression of the ErbB-3 binding protein ebp1 inhibits growth and induces differentiation of human breast cancer cell lines
    • Lessor TJ, Yoo JY, Xia X, Woodford N, Hamburger AW (2000) Ectopic expression of the ErbB-3 binding protein ebp1 inhibits growth and induces differentiation of human breast cancer cell lines. J Cell Physiol 183: 321-329
    • (2000) J Cell Physiol , vol.183 , pp. 321-329
    • Lessor, T.J.1    Yoo, J.Y.2    Xia, X.3    Woodford, N.4    Hamburger, A.W.5
  • 22
    • 33746660688 scopus 로고    scopus 로고
    • Ebp1 isoforms distinctively regulate cell survival and differentiation
    • Liu Z, Ahn JY, Liu X, Ye K (2006) Ebp1 isoforms distinctively regulate cell survival and differentiation. Proc Natl Acad Sci USA 103: 10917-10922
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10917-10922
    • Liu, Z.1    Ahn, J.Y.2    Liu, X.3    Ye, K.4
  • 24
    • 0029783549 scopus 로고    scopus 로고
    • Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations
    • Pinkas-Kramarski R, Shelly M, Glathe S, Ratzkin BJ, Yarden Y (1996a) Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations. J Biol Chem 271: 19029-19032
    • (1996) J Biol Chem , vol.271 , pp. 19029-19032
    • Pinkas-Kramarski, R.1    Shelly, M.2    Glathe, S.3    Ratzkin, B.J.4    Yarden, Y.5
  • 26
    • 0037069388 scopus 로고    scopus 로고
    • Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3
    • Qiu XB, Goldberg AL (2002) Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3. Proc Natl Acad Sci USA 99: 14843-14848
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14843-14848
    • Qiu, X.B.1    Goldberg, A.L.2
  • 27
    • 32944473985 scopus 로고    scopus 로고
    • P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation
    • Rayala SK, Talukder AH, Balasenthil S, Tharakan R, Barnes CJ, Wang RA, Aldaz M, Khan S, Kumar R (2006) P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation. Cancer Res 66: 1694-1701
    • (2006) Cancer Res , vol.66 , pp. 1694-1701
    • Rayala, S.K.1    Talukder, A.H.2    Balasenthil, S.3    Tharakan, R.4    Barnes, C.J.5    Wang, R.A.6    Aldaz, M.7    Khan, S.8    Kumar, R.9
  • 28
    • 33846552656 scopus 로고    scopus 로고
    • Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3
    • Sergina NV, Rausch M, Wang D, Blair J, Hann B, Shokat KM, Moasser MM (2007) Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3. Nature 445: 437-441
    • (2007) Nature , vol.445 , pp. 437-441
    • Sergina, N.V.1    Rausch, M.2    Wang, D.3    Blair, J.4    Hann, B.5    Shokat, K.M.6    Moasser, M.M.7
  • 30
    • 3042620165 scopus 로고    scopus 로고
    • EBP1 is a nucleolar growth-regulating protein that is part of pre-ribosomal ribonucleoprotein complexes
    • Squatrito M, Mancino M, Donzelli M, Areces LB, Draetta GF (2004) EBP1 is a nucleolar growth-regulating protein that is part of pre-ribosomal ribonucleoprotein complexes. Oncogene 23: 4454-4465
    • (2004) Oncogene , vol.23 , pp. 4454-4465
    • Squatrito, M.1    Mancino, M.2    Donzelli, M.3    Areces, L.B.4    Draetta, G.F.5
  • 31
    • 17644387160 scopus 로고    scopus 로고
    • Coexpression of the type 1 growth factor receptor family members HER-1, HER-2, and HER-3 has a synergistic negative prognostic effect on breast carcinoma survival
    • Wiseman SM, Makretsov N, Nielsen TO, Gilks B, Yorida E, Cheang M, Turbin D, Gelmon K, Huntsman DG (2005) Coexpression of the type 1 growth factor receptor family members HER-1, HER-2, and HER-3 has a synergistic negative prognostic effect on breast carcinoma survival. Cancer 103: 1770-1777
    • (2005) Cancer , vol.103 , pp. 1770-1777
    • Wiseman, S.M.1    Makretsov, N.2    Nielsen, T.O.3    Gilks, B.4    Yorida, E.5    Cheang, M.6    Turbin, D.7    Gelmon, K.8    Huntsman, D.G.9
  • 32
    • 0035059136 scopus 로고    scopus 로고
    • Ebp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulation
    • Xia X, Cheng A, Lessor T, Zhang Y, Hamburger AW (2001) Ebp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulation. J Cell Physiol 187: 209-217
    • (2001) J Cell Physiol , vol.187 , pp. 209-217
    • Xia, X.1    Cheng, A.2    Lessor, T.3    Zhang, Y.4    Hamburger, A.W.5
  • 33
    • 0034773992 scopus 로고    scopus 로고
    • The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities
    • Yarden Y (2001) The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. Eur J Cancer 37(Suppl 4): S3-S8
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL. 4
    • Yarden, Y.1
  • 35
    • 27744544281 scopus 로고    scopus 로고
    • The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription
    • Zhang Y, Akinmade D, Hamburger AW (2005) The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription. Nucleic Acids Res 33: 6024-6033
    • (2005) Nucleic Acids Res , vol.33 , pp. 6024-6033
    • Zhang, Y.1    Akinmade, D.2    Hamburger, A.W.3
  • 36
    • 2942703949 scopus 로고    scopus 로고
    • Heregulin regulates the ability of the ErbB3-binding protein Ebp1 to bind E2F promoter elements and repress E2F-mediated transcription
    • Zhang Y, Hamburger AW (2004) Heregulin regulates the ability of the ErbB3-binding protein Ebp1 to bind E2F promoter elements and repress E2F-mediated transcription. J Biol Chem 279: 26126-26133
    • (2004) J Biol Chem , vol.279 , pp. 26126-26133
    • Zhang, Y.1    Hamburger, A.W.2
  • 37
    • 13244283057 scopus 로고    scopus 로고
    • Specificity and heregulin regulation of Ebp1 (ErbB3 binding protein 1) mediated repression of androgen receptor signalling
    • Zhang Y, Hamburger AW (2005) Specificity and heregulin regulation of Ebp1 (ErbB3 binding protein 1) mediated repression of androgen receptor signalling. Br J Cancer 92: 140-146
    • (2005) Br J Cancer , vol.92 , pp. 140-146
    • Zhang, Y.1    Hamburger, A.W.2
  • 39
    • 0038813929 scopus 로고    scopus 로고
    • Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone deacetylases
    • Zhang YX, Woodford N, Xia XM, Hamburger AW (2003) Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone deacetylases. Nucleic Acids Res 31: 2168-2177
    • (2003) Nucleic Acids Res , vol.31 , pp. 2168-2177
    • Zhang, Y.X.1    Woodford, N.2    Xia, X.M.3    Hamburger, A.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.