AAV-mediated Overexpression of Human α7 Integrin Leads to Histological and Functional Improvement in Dystrophic Mice

Molecular Therapy

Volumn 21, Issue 3, 2013, Pages 520-525

  Heller, Kristin N ^a,b   Montgomery, Chrystal L ^a,b   Janssen, Paul ML ^c   Clark, K Reed ^a,b   Mendell, Jerry R ^a,b,c   Rodino Klapac, Louise R ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA7 INTEGRIN; PARVOVIRUS VECTOR;

ALPHA7 INTEGRIN GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SIZE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MEGADOSE; DUCHENNE MUSCULAR DYSTROPHY; GENE; GENE OVEREXPRESSION; GENE REPLACEMENT THERAPY; GENE TRANSFER; LIMB PERFUSION; LOW DRUG DOSE; MOUSE; MUSCLE CELL; MUSCLE TETANIC CONTRACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; VIRAL GENE THERAPY;

ADENO-ASSOCIATED VIRUS; MUS;

EID: 84875221399     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2012.281     Document Type: Article

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