Transgenic overexpression of the α7 integrin reduces muscle pathology and improves viability in the dy W mouse model of merosin-deficient congenital muscular dystrophy type 1A

Journal of Cell Science

Volumn 124, Issue 13, 2011, Pages 2287-2297

  Doe, Jinger A ^a   Wuebbles, Ryan D ^a   Allred, Erika T ^a   Rooney, Jachinta E ^a   Elorza, Margaret ^a   Burkin, Dean J ^a  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

7 Integrin; MDC1A; Muscular Dystrophy; Transgenic Mice

Indexed keywords

ALPHA7 INTEGRIN; BETA1 INTEGRIN; LAMININ ALPHA2; MEROSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DISEASE COURSE; EXTRACELLULAR MATRIX; GENE OVEREXPRESSION; LIFE EXPECTANCY; MALE; MOUSE; MUSCLE DISEASE; MUSCLE FUNCTION; MUSCLE STRENGTH; MUSCULAR DYSTROPHY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SARCOLEMMA; SKELETAL MUSCLE; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD; DISEASE PROGRESSION; EXTRACELLULAR MATRIX; FLUORESCENT ANTIBODY TECHNIQUE; INTEGRIN ALPHA CHAINS; LAMININ; MICE; MICE, TRANSGENIC; MUSCLE STRENGTH; MUSCLE, SKELETAL; MUSCULAR DYSTROPHIES; MUSCULAR DYSTROPHY, ANIMAL; POLYMERASE CHAIN REACTION;

MUS; MUS MUSCULUS;

EID: 79960289893     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.083311     Document Type: Article

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