Differential Effect of Curcumin on the Nanomechanics of Normal and Cancerous Mammalian Epithelial Cells

Cell Biochemistry and Biophysics

Volumn 65, Issue 3, 2013, Pages 399-411

  Saab, Marie belle ^a   Bec, Nicole ^c   Martin, Marta ^a   Estephan, Elias ^a,b   Cuisinier, Frédéric ^b   Larroque, Christian ^c   Gergely, Csilla ^a  

^a UNIVERSITÉ MONTPELLIER 2   (France)

^b University Montpellier   (France)

^c INSTITUT DE RECHERCHE EN CANCÉROLOGIE DE MONTPELLIER   (France)

Author keywords

Atomic force microscopy; Curcumin; Elasticity measurements; Fluorescence; HMEC; Mammalian cells; MCF7

Indexed keywords

MAMMALIA;

EID: 84875218731     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-012-9443-1     Document Type: Article

References (44)

1. Lekka, M., Laidler, P., Gil, D., Lekki, J., Stachura, Z., & Hrynkiewicz, A. Z. (1999). Elasticity of normal and cancerous human bladder cells studied by scanning force microscopy. European Biophysics Journal, 28, 312-316.
2. Lekka, M., Lekki, J., Marszałek, M., Golonka, P., Stachura, Z., Cleff, B., et al. (1999). Local elastic properties of cells studied by SFM. Applied Surface Science, 141, 345-349.
3. Berdyyeva, T. K., Woodworth, C. D., & Sokolov, I. (2005). Human epithelial cells increase their rigidity with ageing in vitro: Direct measurements. Physics in Medicine and Biology, 50, 81-92.
4. Yamazaki, D., Kurisu, S., & Takenawa, T. (2005). Regulation of cancer cell motility through actin reorganization. Cancer Science, 96, 379-386.
5. Rao, J., & Li, N. (2004). Microfilament actin remodeling as a potential target for cancer drug development. Current Cancer Drug Targets, 4, 267-283.
6. Goldmann, W. H., & Ezzell, R. M. (1996). Viscoelasticity in wild-type and vinculin-deficient (5. 51) mouse F9 embryonic carcinoma cells examined by atomic force microscopy and rheology. Experimental Cell Research, 1996(226), 234-237.
7. Goldmann, W. H., Galneder, R., Ludwig, M., Xu, W. M., Adamson, E. D., Wang, N., et al. (1998). Differences in elasticity of vinculin-deficient F9 cells measured by magnetometry and atomic force microscopy. Experimental Cell Research, 239, 235-242.
8. Discher, D., Janmey, P., & Wang, Y. (2005). Tissue cells feel and respond to the stiffness of their substrate. Science, 310, 1139-1143.
9. McKnight, A. L., Kugel, J. L., Rossman, P. J., Manduca, A., Hartmann, L. C., & Ehman, R. L. (2002). MR elastography of breast cancer: Preliminary results. American Journal of Roentgenology, 178, 1411-1417.
10. Bercoff, J., Chaffaï, S., Tanter, M., Sandrin, L., Catheline, S., Fink, M., et al. (2003). In vivo breast tumor detection using transient elastography. Ultrasound in Medicine and Biology, 29, 1387-1396.
11. Rotsch, C., & Radmacher, M. (2000). Drug-induced changes of cytoskeletal structure and mechanics in fibroblasts: An atomic force microscopy study. Biophysical Journal, 78, 520-535.
12. Suresh, S., Spatz, J., Mills, J. P., Micoulet, A., Dao, M., Lim, C. T., et al. (2005). Connections between single-cell biomechanics and human disease states: Gastrointestinal cancer and malaria. Acta Biomaterialia, 1, 15-30.
13. Guck, J., Schinkinger, S., Lincoln, B., Wottawah, F., Ebert, S., Romeyke, M., et al. (2005). Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence. Biophysical Journal, 88, 3689-3698.
14. Suresh, S. (2007). Biomechanics and biophysics of cancer cell. Acta Biomaterialia, 3, 413-438.
15. Cross, S. E., Jin, Y. S., Rao, J., & Gimzewski, J. K. (2007). Nanomechanical analysis of cells from cancer patients. Nature Nanotechnology, 2, 780-783.
16. Binnig, G., Quate, C. F., & Gerber, C. (1986). Atomic force microscope. Physical Review Letters, 56, 930-933.
17. Radmacher, M., Tillamnn, R. W., Fritz, M., & Gaub, H. E. (1992). From molecules to cells: Imaging soft samples with the atomic force microscope. Science, 257, 1900-1905.
18. Hansma, P. K., Elings, V. B., Marti, O., & Bracker, C. E. (1988). Scanning tunneling microscopy and atomic force microscopy: Application to biology and technology. Science, 242, 209-216.
19. Domke, J., Danno, S., Parak, W. J., Muller, O., Aicher, W. K., & Radmacher, M. (2000). Substrate dependent differences in morphology and elasticity of living osteoblasts investigated by atomic force microscopy. Colloid Surface B., 19, 367-379.
20. Hertz, H. (1881). Über die Berührung fester elastischer Körper. J Reine Angew Math, 92, 156-171.
21. Charras, G. T., & Horton, M. A. (2002). Single cell mechanotransduction and its modulation analyzed by atomic force microscopy indentation. Biophysical Journal, 2002(82), 2970-2981.
22. Dufrene, Y. F. (2002). Atomic force microscopy, a powerful tool in microbiology. Journal of Bacteriology, 2002(184), 5205-5213.
23. Balint, Z., Krizbai, I. A., Wilhelm, I., Farkas, A. E., Parducz, A., Szegletes, Z., et al. (2007). Changes induced by hyperosmotic mannitol in cerebral endothelial cells: An atomic force microscopic study. European Biophysics Journal, 36, 113-120.
24. Rotsch, C., Braet, F., Wisse, E., & Radmacher, M. (1997). AFM imaging and elasticity measurements on living rat liver macrophages. Cell Biology International, 21, 685-696.
25. Aggarwal, B. B., & Shishodia, S. (2006). Molecular targets of dietary agents for prevention and therapy of cancer. Biochemical Pharmacology, 2006(71), 1397-1421.
26. Choi, H., Chun, Y. S., Kim, S. W., Kim, M. S., & Park, J. W. (2006). Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: A mechanism of tumor growth inhibition. Molecular Pharmacology, 70, 1664-1671.
27. Shukla, P. K., Khanna, V. K., Ali, M. M., Khan, M. Y., & Srimal, R. (2008). CAnti-ischemic effect of curcumin in rat brain. Neurochemical Research, 33, 1036-1043.
28. Stix, G. (2007). Spice healer. Scientific American, 296, 66-69.
29. Shukla, P. K., Khanna, V. K., Khan, M. Y., & Srimal, R. C. (2003). Protective effect of curcumin against lead neurotoxicity in rat. Human and Experimental Toxicology, 22, 653-658.
30. Jutooru, I., Chadalapaka, G., Lei, P., & Safe, S. (2010). Inhibition of NFKB and pancreatic cancer cell and tumor growth by curcumin is independent on specificity protein down-regulation. Journal of Biological Chemistry, 285, 25332-25344.
31. Sluzarc, A., Shenouda, N. S., Sakla, M. S., Drenkhaln, S. K., Narula, A. S., MacDonald, R. S., et al. (2010). Common botanical compounds inhibit the Hedgehog signalling pathway in prostate cancer. Cancer Research, 70, 3382-3390.
32. Dupont-Gillain, Ch. C., Pamula, E., Denis, F. A., De Cupere, V. M., Dufrene, Y. F., & Rouxhet, P. G. (2004). Controlling the supramolecular organisation of adsorbed collagen layers. Journal of Material Science Materials in Medicine, 15, 347-353.
33. Johnson, K. L. (1994). Contact mechanics. Cambridge: Cambridge University Press.
34. Gupta, K. K., Bharne, S. S., Rathinasamy, K., Naik, N. R., & Panda, D. (2006). Dietary antioxidant curcumin inhibits microtubule assembly through tubulin binding. FEBS Journal, 273, 5320-5332.
35. Holy, J. M. (2002). Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells. Mutation Research, 2002(518), 71-84.
36. Bannerjee, M., Singh, P., & Panda, D. (2010). Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells. FEBS Journal, 277, 3437-3448.
37. Larroque, C., Lacroix, B., Galeotti, N., & Jouin, P. (2005). Quantitative and qualitative analysis of tubulin isoforms by mass spectrometry. Molecular and Cell Proteomics., 4, s324.
38. Bec, N., Lacroix, B., Jouin, P., & Larroque, C. (2006). Study of the native microtubule proteome by MALDI-TOF MS. Molecular and Cell Proteomics., 2006(5), s303.
39. Saab, M. B., Estephan, E., Bec, N., Larroque, M., Aulombard, R., Cloitre, T., et al. (2011). Multi-microscopic study of curcumin effect on fixed non-malignant and cancerous mammalian epithelial cells. Journal of Biophotonics, 4, 533-543.
40. Kunwar, A., Barik, A., Mishra, B., Rathinasamy, K., Pandey, R., & Priyadarsini, K. I. (2008). Quantitative cellular uptake, localization and cytotoxicity of curcumin in normal and tumor cells. Biochimica et Biophysica Acta, 1780, 673-679.
41. Schaaf, C., Shan, B., Buchfelder, M., Losa, M., Kreutzer, J., Rachinger, W., et al. (2009). Curcumin acts as anti-tumorigenic and hormone-suppressive agent in murine and human pituitary tumour cells in vitro and in vivo. Endocrine-Related Cancer, 16, 1339-1350.
42. Prasanth, R., Nair, G., & Girish, C. M. (2011). Enhanced endocytosis of nano-curcumin in nasopharyngeal cancer cells: An atomic force microscopy study. Applied Physics Letters, 99, 163706. doi: 10. 1063/1. 3653388.
43. Li, Q. S., Lee, G. Y., Ong, C. N., & Lim, C. T. (2008). AFM indentation study of breast cancer cells. Biochemical and Biophysical Research Communications, 2008(374), 609-613.
44. Beil, M., Micoulet, A., von Wichert, G., Paschke, S., Walther, P., Omary, M. B., et al. (2003). Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells. Nature Cell Biology, 2003, 803-811.