A new series of N2-substituted-5-(p-toluenesulfonylamino)phthalimide analogues as α-glucosidase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 7, 2013, Pages 2022-2026

  Bian, Xiaoli ^a   Wang, Qian ^b   Ke, Changhu ^a   Zhao, Guilan ^a   Li, Yiping ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Glucosidase inhibitors; 5 (p Toluenesulfonylamino)phthalimide; Diabetes; Postprandial hyperglycemia

Indexed keywords

5 (PARA TOLUENESULFONYLAMINO)PHTHALIMIDE; ALPHA GLUCOSIDASE; ALPHA GLUCOSIDASE INHIBITOR; AMYLASE; GLYCOSIDASE; PHTHALIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DRUG BINDING; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; INTESTINE; NONHUMAN; REDUCTION; STRUCTURE ACTIVITY RELATION; SULFONYLATION;

ALPHA-GLUCOSIDASES; ANIMALS; BETA-GALACTOSIDASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLYCOSIDE HYDROLASES; INTESTINES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHTHALIMIDES; RATS; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP; TOSYL COMPOUNDS;

RATTUS;

EID: 84875214960     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.02.011     Document Type: Article

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