Novel imidazophenoxazine-4-sulfonamides: Their synthesis and evaluation as potential inhibitors of PDE4

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 7, 2013, Pages 1952-1963

  Reddy, Seelam Venkata ^a   Rao, Gangula Mohan ^a   Kumar, Baru Vijaya ^a   Meda, Chandana L T ^b   Deora, Girdhar Singh ^b   Kumar, K Shiva ^b   Parsa, Kishore V L ^b   Pal, Manojit ^b  

^a CKM Arts and Science College   (India)

^b INSTITUTE OF LIFE SCIENCES   (India)

Author keywords

Docking; Imidazophenoxazine; PDE4; Sulfonamide

Indexed keywords

1 (2 BROMOPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (2 CHLOROPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (2 HYDROXYPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (2,3 DICHLOROPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (2,6 DICHLOROPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (3 BROMOPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (3 HYDROXYPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (3 NITROPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (4 (DIETHYLAMINO) 2 HYDROXYPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (4 CHLOROPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (4 DIMETHYLAMINOPHENYL)IMIDAZO [4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (4 HYDROXY 3 METHOXYPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (4 HYDROXYPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (4 METHOXYPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 (5 BROMO 2 FLUOROPHENYL)IMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; 1 PHENYLIMIDAZO[4,5,1 KL]PHENOXAZINE 4 SULFONAMIDE; IMIDAZOPHENOXAZINE 4 SULFONAMIDE DERIVATIVE; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM; SULFONAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; MOLECULAR DOCKING; PHARMACOPHORE;

ANIMALS; CELL LINE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; MOLECULAR DOCKING SIMULATION; OXAZINES; PHOSPHODIESTERASE 4 INHIBITORS; SULFONAMIDES;

EID: 84875211931     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.01.023     Document Type: Article

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