Thymoma in myasthenia gravis: From diagnosis to treatment

Autoimmune Diseases

Volumn 1, Issue 1, 2011, Pages

  Romi, Fredrik ^a  

^a HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AZATHIOPRINE; CHOLINERGIC RECEPTOR ANTIBODY; CONNECTIN; CONNECTIN ANTIBODY; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENT; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; RITUXIMAB; RYANODINE RECEPTOR; RYANODINE RECEPTOR ANTIBODY; TACROLIMUS; UNCLASSIFIED DRUG;

ADD ON THERAPY; ANAMNESIS; CLINICAL FEATURE; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; ELECTROMYOGRAPHY; GROUPS BY AGE; HISTOPATHOLOGY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MYASTHENIA GRAVIS; NEUROMUSCULAR TRANSMISSION; PLASMAPHERESIS; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; REVIEW; THYMECTOMY; THYMOMA;

EID: 84875208121     PISSN: None     EISSN: 20900430     Source Type: Journal    
DOI: 10.4061/2011/474512     Document Type: Review

References (44)

1. Cheney R. T., The biologic spectrum of thymic epithelial neoplasms: current status and future prospects JNCCN Journal of the National Comprehensive Cancer Network 2010 8 11 1322 1328
2. Mller-Hermelink H. K., Marx A., Kirchner T., The pathological basis of thymoma-associated myasthenia gravis Annals of the New York Academy of Sciences 1993 681 56 65 (Pubitemid 23233806)
3. Mller-Hermelink H. K., Marx A., Pathological aspects of malignant and benign thymic disorders Annals of Medicine 1999 31 2 5 14 (Pubitemid 29497700)
4. Strobel P., Rosenwald A., Beyersdorf N., Kerkau T., Eiert O., Murumgi A., Sillanp N., Peterson P., Hummel V., Rieckmann P., Burek C., Schalke B., Nix W., Kiefer R., Mller-Hermelink H. K., Marx A., Selective loss of regulatory T cells in thymomas Annals of Neurology 2004 56 6 901 904 (Pubitemid 39578459)
5. Marx A., Willcox N., Leite M. I., Chuang W. Y., Schalke B., Nix W., Strbel P., Thymoma and paraneoplastic myasthenia gravis Autoimmunity 2010 43 5-6 413 427
6. Marx A., Kirchner T., Hoppe F., O'Connor R., Schalke B., Tzartos S., Muller-Hermelink H. K., Proteins with epitopes of the acetylcholine receptor in epithelial cell cultures of thymomas in myasthenia gravis American Journal of Pathology 1989 134 4 865 877 (Pubitemid 19111253)
7. Romi F., Bo L., Skeie G. O., Myking A., Aarli J. A., Gilhus N. E., Titin and ryanodine receptor epitopes are expressed in cortical thymoma along with costimulatory molecules Journal of Neuroimmunology 2002 128 1-2 82 89 (Pubitemid 34722367)
8. Skeie G. O., Bentsen P. T., Freiburg A., Aarli J. A., Gilhus N. E., Cell-mediated immune response against titin in myasthenia gravis: evidence for the involvement of Th1 and Th2 cells Scandinavian Journal of Immunology 1998 47 1 76 81 (Pubitemid 28057355)
9. Gilhus N. E., Willcox N., Harcourt G., Nagvekar N., Beeson D., Vincent A., Newsom-Davis J., Antigen presentation by thymoma epithelial cells from myasthenia gravis patients to potentially pathogenic T cells Journal of Neuroimmunology 1995 56 1 65 76
10. Chuang W. Y., Scrbel P., Gold R., Nix W., Schalke B., Kiefer R., Opitz A., Klinker E., Mller-Hermelink H. K., Marx A., A CTLA4high genotype is associated with myasthenia gravis in thymoma patients Annals of Neurology 2005 58 4 644 648 (Pubitemid 41377232)
11. Amdahl C., Alseth E. H., Gilhus N. E., Nakkestad H. L., Skeie G. O., Polygenic disease associations in thymomatous myasthenia gravis Archives of Neurology 2007 64 12 1729 1733 (Pubitemid 350254934)
12. Vincent A., Palace J., Hilton-Jones D., Myasthenia gravis Lancet 2001 357 9274 2122 2128 (Pubitemid 32607461)
13. Romi F., Skeie G. O., Aarli J. A., Gilhus N. E., Muscle autoantibodies in subgroups of myasthenia gravis patients Journal of Neurology 2000 247 5 369 375 (Pubitemid 30364616)
14. Albert M. L., Darnell R. B., Paraneoplastic neurological degenerations: keys to tumour immunity Nature Reviews Cancer 2004 4 1 36 44 (Pubitemid 38082152)
15. Lindstrom J. M., Acetylcholine receptors and myasthenia Muscle and Nerve 2000 23 4 453 477 (Pubitemid 30164770)
16. Aarli J. A., Late-onset myasthenia gravis: a changing scene Archives of Neurology 1999 56 1 25 27 (Pubitemid 29046905)
17. Skeie G. O., Mygland Å., Aarli J. A., Gilhus N. E., Titin antibodies in patients with late onset myasthenia gravis: clinical correlations Autoimmunity 1995 20 2 99 104
18. Baggi F., Andreetta F., Antozzi C., Simoncini O., Confalonieri P., Labeit S., Cornelio F., Mantegazza R., Anti-titin and antiryanodine receptor antibodies in myasthenia gravis patients with thymoma Annals of the New York Academy of Sciences 1998 841 538 541 (Pubitemid 28362898)
19. Romi F., Gilhus N. E., Varhaug J. E., Myking A., Aarli J. A., Disease severity and outcome in thymoma myasthenia gravis: a long-term observation study European Journal of Neurology 2003 10 6 701 706 (Pubitemid 38030881)
20. Romi F., Skeie G. O., Gilhus N. E., Aarli J. A., Striational antibodies in myasthenia gravis: reactivity and possible clinical significance Archives of Neurology 2005 62 3 442 446 (Pubitemid 40349480)
21. Granzier H., Labeit S., Structure-function relations of the giant elastic protein titin in striated and smooth muscle cells Muscle and Nerve 2007 36 6 740 755 (Pubitemid 350246923)
22. Somnier F. E., Skeie G. O., Aarli J. A., Trojaborg W., EMG evidence of myopathy and the occurrence of titin autoantibodies in patients with myasthenia gravis European Journal of Neurology 1999 6 5 555 563 (Pubitemid 30028810)
23. Luckman S. P., Skeie G. O., Helgeland G., Gilhus N. E., Morphological effects of myasthenia gravis patient sera on human muscle cells Muscle and Nerve 2006 33 1 93 103 (Pubitemid 43062991)
24. Zorzato F., Fujii J., Otsu K., Phillips M., Green N. M., Lai F. A., Meissner G., MacLennan D. H., Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum Journal of Biological Chemistry 1990 265 4 2244 2256
25. Iwasa K., Komai K., Takamori M., Spontaneous thymoma rat as a model for myasthenic weakness caused by anti-ryanodine receptor antibodies Muscle and Nerve 1998 21 12 1655 1660 (Pubitemid 28545694)
26. Pagala M. K. D., Nandakumar N. V., Venkatachari S. A. T., Ravindran K., Namba T., Grob D., Responses of intercostal muscle biopsies from normal subjects and patients with myasthenia gravis Muscle and Nerve 1990 13 11 1012 1022 (Pubitemid 20356212)
27. Romi F., Aarli J. A., Gilhus N. E., Myasthenia gravis patients with ryanodine receptor antibodies have distinctive clinical features European Journal of Neurology 2007 14 6 617 620 (Pubitemid 46849058)
28. Aarli J. A., Stefansson K., Marton L. S. G., Wollmann R. L., Patients with myasthenia gravis and thymoma have in their sera IgG autoantibodies against titin Clinical and Experimental Immunology 1990 82 2 284 288 (Pubitemid 20359537)
29. Romi F., Gilhus N. E., Aarli J. A., Myasthenia gravis: clinical, immunological, and therapeutic advances Acta Neurologica Scandinavica 2005 111 2 134 141 (Pubitemid 40175337)
30. Suzuki S., Utsugisawa K., Nagane Y., Satoh T., Kuwana M., Suzuki N., Clinical and immunological differences between early and late-onset myasthenia gravis in Japan Journal of Neuroimmunology 2011 230 1-2 148 152
31. Liu W., Tong T., Ji Z., Zhang Z., Long-term prognostic analysis of thymectomized patients with myasthenia gravis Chinese Medical Journal 2002 115 2 235 237
32. Oosterhuis H. J. G. H., Limburg P. C., Hummel Tappel E., Anti-acetylcholine receptor antibodies in myasthenia gravis. II. Clinical and serological follow-up of individual patients Journal of the Neurological Sciences 1983 58 3 371 385 (Pubitemid 13138257)
33. Pascuzzi R. M., The edrophonium test Seminars in Neurology 2003 23 1 83 88 (Pubitemid 36857712)
34. Meriggioli M. N., Sanders D. B., Advances in the diagnosis of neuromuscular junction disorders American Journal of Physical Medicine and Rehabilitation 2005 84 8 627 638 (Pubitemid 41026130)
35. Wang W. W., Hao H. J., Gao F., Detection of multiple antibodies in myasthenia gravis and its clinical significance Chinese Medical Journal 2010 123 18 2555 2558
36. Gajdos P., Chevret S., Toyka K., Plasma exchange for myasthenia gravis Cochrane Database of Systematic Reviews 2002 4
37. Buckley C., Newsom-Davis J., Willcox N., Vincent A., Do titin and cytokine antibodies in MG patients predict thymoma or thymoma recurrence? Neurology 2001 57 9 1579 1582 (Pubitemid 33055473)
38. Zahid I., Sharif S., Routledge T., Scarci M., Video-assisted thoracoscopic surgery or transsternal thymectomy in the treatment of myasthenia gravis? Interactive Cardiovascular and Thoracic Surgery 2011 12 1 40 46
39. Gajdos P., Chevret S., Toyka K., Intravenous immunoglobulin for myasthenia gravis Cochrane Database of Systematic Reviews 2003 2
40. Venuta F., Rendina E. A., De Giacomo T., Rocca G. D., Antonini G., Ciccone A. M., Ricci C., Coloni G. F., Thymectomy for myasthenia gravis: a 27-year experience European Journal of Cardio-Thoracic Surgery 1999 15 5 621 625 (Pubitemid 29251757)
41. Richman D. P., Agius M. A., Treatment of autoimmune myasthenia gravis Neurology 2003 61 12 1652 1661 (Pubitemid 38020807)
42. Sanders D. B., Evoli A., Immunosuppressive therapies in myasthenia gravis Autoimmunity 2010 43 5-6 428 435
43. Konishi T., Yoshiyama Y., Takamori M., Yagi K., Mukai E., Saida T., Clinical study of FK506 in patients with myasthenia gravis Muscle and Nerve 2003 28 5 570 574 (Pubitemid 37339910)
44. Takamori M., Motomura M., Kawaguchi N., Nemoto Y., Hattori T., Yoshikawa H., Otsuka K., Anti-ryanodine receptor antibodies and FK506 in myasthenia gravis Neurology 2004 62 10 1894 1896 (Pubitemid 38661763)