-
1
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E, (2010) Cancer statistics, 2010. CA Cancer J Clin 60: 277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
2
-
-
79959724356
-
Pancreatic cancer treatment and research: an international expert panel discussion
-
Tempero MA, Berlin J, Ducreux M, Haller D, Harper P, et al. (2011) Pancreatic cancer treatment and research: an international expert panel discussion. Ann Oncol 22: 1500-1506.
-
(2011)
Ann Oncol
, vol.22
, pp. 1500-1506
-
-
Tempero, M.A.1
Berlin, J.2
Ducreux, M.3
Haller, D.4
Harper, P.5
-
3
-
-
60149107489
-
The sine oculis homeobox (SIX) family of transcription factors as regulators of development and disease
-
Kumar JP, (2009) The sine oculis homeobox (SIX) family of transcription factors as regulators of development and disease. Cell Mol Life Sci 66: 565-583.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 565-583
-
-
Kumar, J.P.1
-
4
-
-
84856739365
-
Dual transcriptional activities of SIX proteins define their roles in normal and ectopic eye development
-
Anderson AM, Weasner BM, Weasner BP, Kumar JP, (2012) Dual transcriptional activities of SIX proteins define their roles in normal and ectopic eye development. Development 139: 991-1000.
-
(2012)
Development
, vol.139
, pp. 991-1000
-
-
Anderson, A.M.1
Weasner, B.M.2
Weasner, B.P.3
Kumar, J.P.4
-
5
-
-
0032514597
-
Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis
-
Ford HL, Kabingu EN, Bump EA, Mutter GL, Pardee AB, (1998) Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis. Proc Natl Acad Sci U S A 95: 12608-12613.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 12608-12613
-
-
Ford, H.L.1
Kabingu, E.N.2
Bump, E.A.3
Mutter, G.L.4
Pardee, A.B.5
-
6
-
-
10344262883
-
Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes
-
Zou D, Silvius D, Fritzsch B, Xu PX, (2004) Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes. Development 131: 5561-5572.
-
(2004)
Development
, vol.131
, pp. 5561-5572
-
-
Zou, D.1
Silvius, D.2
Fritzsch, B.3
Xu, P.X.4
-
7
-
-
0041853845
-
Six1 is required for the early organogenesis of mammalian kidney
-
Xu PX, Zheng W, Huang L, Maire P, Laclef C, et al. (2003) Six1 is required for the early organogenesis of mammalian kidney. Development 130: 3085-3094.
-
(2003)
Development
, vol.130
, pp. 3085-3094
-
-
Xu, P.X.1
Zheng, W.2
Huang, L.3
Maire, P.4
Laclef, C.5
-
8
-
-
70349205537
-
Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition
-
McCoy EL, Iwanaga R, Jedlicka P, Abbey NS, Chodosh LA, et al. (2009) Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition. J Clin Invest 119: 2663-2677.
-
(2009)
J Clin Invest
, vol.119
, pp. 2663-2677
-
-
McCoy, E.L.1
Iwanaga, R.2
Jedlicka, P.3
Abbey, N.S.4
Chodosh, L.A.5
-
9
-
-
0038016516
-
Thymus, kidney and craniofacial abnormalities in Six 1 deficient mice
-
Laclef C, Souil E, Demignon J, Maire P, (2003) Thymus, kidney and craniofacial abnormalities in Six 1 deficient mice. Mech Dev 120: 669-679.
-
(2003)
Mech Dev
, vol.120
, pp. 669-679
-
-
Laclef, C.1
Souil, E.2
Demignon, J.3
Maire, P.4
-
10
-
-
33749234949
-
Six1 and Six4 promote survival of sensory neurons during early trigeminal gangliogenesis
-
Konishi Y, Ikeda K, Iwakura Y, Kawakami K, (2006) Six1 and Six4 promote survival of sensory neurons during early trigeminal gangliogenesis. Brain Res 1116: 93-102.
-
(2006)
Brain Res
, vol.1116
, pp. 93-102
-
-
Konishi, Y.1
Ikeda, K.2
Iwakura, Y.3
Kawakami, K.4
-
11
-
-
16844372087
-
Gene amplification is a mechanism of Six1 overexpression in breast cancer
-
Reichenberger KJ, Coletta RD, Schulte AP, Varella-Garcia M, Ford HL, (2005) Gene amplification is a mechanism of Six1 overexpression in breast cancer. Cancer Res 65: 2668-2675.
-
(2005)
Cancer Res
, vol.65
, pp. 2668-2675
-
-
Reichenberger, K.J.1
Coletta, R.D.2
Schulte, A.P.3
Varella-Garcia, M.4
Ford, H.L.5
-
12
-
-
0036087979
-
Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition
-
Li CM, Guo M, Borczuk A, Powell CA, Wei M, et al. (2002) Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition. Am J Pathol 160: 2181-2190.
-
(2002)
Am J Pathol
, vol.160
, pp. 2181-2190
-
-
Li, C.M.1
Guo, M.2
Borczuk, A.3
Powell, C.A.4
Wei, M.5
-
13
-
-
1442304609
-
Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators
-
Yu Y, Khan J, Khanna C, Helman L, Meltzer PS, et al. (2004) Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Nat Med 10: 175-181.
-
(2004)
Nat Med
, vol.10
, pp. 175-181
-
-
Yu, Y.1
Khan, J.2
Khanna, C.3
Helman, L.4
Meltzer, P.S.5
-
14
-
-
33750207050
-
Clinicopathological significance of homeoprotein Six1 in hepatocellular carcinoma
-
Ng KT, Man K, Sun CK, Lee TK, Poon RT, et al. (2006) Clinicopathological significance of homeoprotein Six1 in hepatocellular carcinoma. Br J Cancer 95: 1050-1055.
-
(2006)
Br J Cancer
, vol.95
, pp. 1050-1055
-
-
Ng, K.T.1
Man, K.2
Sun, C.K.3
Lee, T.K.4
Poon, R.T.5
-
15
-
-
34248162523
-
Six1 overexpression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival
-
Behbakht K, Qamar L, Aldridge CS, Coletta RD, Davidson SA, et al. (2007) Six1 overexpression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival. Cancer Res 67: 3036-3042.
-
(2007)
Cancer Res
, vol.67
, pp. 3036-3042
-
-
Behbakht, K.1
Qamar, L.2
Aldridge, C.S.3
Coletta, R.D.4
Davidson, S.A.5
-
16
-
-
77956342464
-
MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers
-
Imam JS, Buddavarapu K, Lee-Chang JS, Ganapathy S, Camosy C, et al. (2010) MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers. Oncogene 29: 4971-4979.
-
(2010)
Oncogene
, vol.29
, pp. 4971-4979
-
-
Imam, J.S.1
Buddavarapu, K.2
Lee-Chang, J.S.3
Ganapathy, S.4
Camosy, C.5
-
17
-
-
85027953636
-
Expression and significance of Six1 and Ezrin in cervical cancer tissue
-
Tan J, Zhang C, Qian J, (2011) Expression and significance of Six1 and Ezrin in cervical cancer tissue. Tumour Biol 32: 1241-1247.
-
(2011)
Tumour Biol
, vol.32
, pp. 1241-1247
-
-
Tan, J.1
Zhang, C.2
Qian, J.3
-
18
-
-
85026153280
-
Expression and clinical implications of homeobox gene Six1 in cervical cancer cell lines and cervical epithelial tissues
-
Zheng XH, Liang PH, Guo JX, Zheng YR, Han J, et al. (2010) Expression and clinical implications of homeobox gene Six1 in cervical cancer cell lines and cervical epithelial tissues. Int J Gynecol Cancer 20: 1587-1592.
-
(2010)
Int J Gynecol Cancer
, vol.20
, pp. 1587-1592
-
-
Zheng, X.H.1
Liang, P.H.2
Guo, J.X.3
Zheng, Y.R.4
Han, J.5
-
19
-
-
42049120053
-
Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation
-
Coletta RD, Christensen KL, Micalizzi DS, Jedlicka P, Varella-Garcia M, et al. (2008) Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation. Cancer Res 68: 2204-2213.
-
(2008)
Cancer Res
, vol.68
, pp. 2204-2213
-
-
Coletta, R.D.1
Christensen, K.L.2
Micalizzi, D.S.3
Jedlicka, P.4
Varella-Garcia, M.5
-
20
-
-
2342590630
-
The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1
-
Coletta RD, Christensen K, Reichenberger KJ, Lamb J, Micomonaco D, et al. (2004) The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1. Proc Natl Acad Sci U S A 101: 6478-6483.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 6478-6483
-
-
Coletta, R.D.1
Christensen, K.2
Reichenberger, K.J.3
Lamb, J.4
Micomonaco, D.5
-
21
-
-
70349213381
-
The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling
-
Micalizzi DS, Christensen KL, Jedlicka P, Coletta RD, Barón AE, et al. (2009) The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling. J Clin Invest 119: 2678-2690.
-
(2009)
J Clin Invest
, vol.119
, pp. 2678-2690
-
-
Micalizzi, D.S.1
Christensen, K.L.2
Jedlicka, P.3
Coletta, R.D.4
Barón, A.E.5
-
22
-
-
84860172725
-
SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer
-
Wang CA, Jedlicka P, Patrick AN, Micalizzi DS, Lemmer KC, et al. (2012) SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer. J Clin Invest 122: 1895-1906.
-
(2012)
J Clin Invest
, vol.122
, pp. 1895-1906
-
-
Wang, C.A.1
Jedlicka, P.2
Patrick, A.N.3
Micalizzi, D.S.4
Lemmer, K.C.5
-
23
-
-
77954709872
-
Suppression of tumorigenesis and metastasis of hepatocellular carcinoma by shRNA interference targeting on homeoprotein Six1
-
Ng KT, Lee TK, Cheng Q, Wo JY, Sun CK, et al. (2010) Suppression of tumorigenesis and metastasis of hepatocellular carcinoma by shRNA interference targeting on homeoprotein Six1. Int J Cancer 127: 859-872.
-
(2010)
Int J Cancer
, vol.127
, pp. 859-872
-
-
Ng, K.T.1
Lee, T.K.2
Cheng, Q.3
Wo, J.Y.4
Sun, C.K.5
-
24
-
-
44949231424
-
Analyzing real-time PCR data by the comparative C(T) method
-
Schmittgen TD, Livak KJ, (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3: 1101-1108.
-
(2008)
Nat Protoc
, vol.3
, pp. 1101-1108
-
-
Schmittgen, T.D.1
Livak, K.J.2
-
25
-
-
1642377561
-
ONCOMINE: a cancer microarray database and integrated data-mining platform
-
Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, et al. (2004) ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia 6: 1-6.
-
(2004)
Neoplasia
, vol.6
, pp. 1-6
-
-
Rhodes, D.R.1
Yu, J.2
Shanker, K.3
Deshpande, N.4
Varambally, R.5
-
26
-
-
79959982288
-
hSav1 interacts with HAX1 and attenuates its anti-apoptotic effects in MCF-7 breast cancer cells
-
Luo X, Li Z, Li X, Wang G, Liu W, et al. (2011) hSav1 interacts with HAX1 and attenuates its anti-apoptotic effects in MCF-7 breast cancer cells. Int J Mol Med 28: 349-355.
-
(2011)
Int J Mol Med
, vol.28
, pp. 349-355
-
-
Luo, X.1
Li, Z.2
Li, X.3
Wang, G.4
Liu, W.5
-
27
-
-
84857383269
-
DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma
-
Zhang G, Schetter A, He P, Funamizu N, Gaedcke J, et al. (2012) DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma. PLoS One 7: e31507.
-
(2012)
PLoS One
, vol.7
-
-
Zhang, G.1
Schetter, A.2
He, P.3
Funamizu, N.4
Gaedcke, J.5
-
28
-
-
60849121964
-
Combined gene expression analysis of whole-tissue and microdissected pancreatic ductal adenocarcinoma identifies genes specifically overexpressed in tumor epithelia
-
Badea L, Herlea V, Dima SO, Dumitrascu T, Popescu I, (2008) Combined gene expression analysis of whole-tissue and microdissected pancreatic ductal adenocarcinoma identifies genes specifically overexpressed in tumor epithelia. Hepatogastroenterology 55: 2016-2027.
-
(2008)
Hepatogastroenterology
, vol.55
, pp. 2016-2027
-
-
Badea, L.1
Herlea, V.2
Dima, S.O.3
Dumitrascu, T.4
Popescu, I.5
-
29
-
-
84863278019
-
Integrative survival-based molecular profiling of human pancreatic cancer
-
Donahue TR, Tran LM, Hill R, Li Y, Kovochich A, et al. (2012) Integrative survival-based molecular profiling of human pancreatic cancer. Clin Cancer Res 18: 1352-1363.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1352-1363
-
-
Donahue, T.R.1
Tran, L.M.2
Hill, R.3
Li, Y.4
Kovochich, A.5
-
30
-
-
64249116807
-
The human WW45 protein enhances MST1-mediated apoptosis in vivo
-
Luo X, Li Z, Yan Q, Li X, Tao D, et al. (2009) The human WW45 protein enhances MST1-mediated apoptosis in vivo. Int J Mol Med 23: 357-362.
-
(2009)
Int J Mol Med
, vol.23
, pp. 357-362
-
-
Luo, X.1
Li, Z.2
Yan, Q.3
Li, X.4
Tao, D.5
-
31
-
-
0035253406
-
Specific down-regulation of an engineered human cyclin D1 promoter by a novel DNA-binding ligand in intact cells
-
Laurance ME, Starr DB, Michelotti EF, Cheung E, Gonzalez C, et al. (2001) Specific down-regulation of an engineered human cyclin D1 promoter by a novel DNA-binding ligand in intact cells. Nucleic Acids Res 29: 652-661.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 652-661
-
-
Laurance, M.E.1
Starr, D.B.2
Michelotti, E.F.3
Cheung, E.4
Gonzalez, C.5
-
32
-
-
23844444229
-
Experimental trial for diagnosis of pancreatic ductal carcinoma based on gene expression profiles of pancreatic ductal cells
-
Ishikawa M, Yoshida K, Yamashita Y, Ota J, Takada S, et al. (2005) Experimental trial for diagnosis of pancreatic ductal carcinoma based on gene expression profiles of pancreatic ductal cells. Cancer Sci 96: 387-393.
-
(2005)
Cancer Sci
, vol.96
, pp. 387-393
-
-
Ishikawa, M.1
Yoshida, K.2
Yamashita, Y.3
Ota, J.4
Takada, S.5
-
33
-
-
27144454969
-
Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions
-
Buchholz M, Braun M, Heidenblut A, Kestler HA, Klöppel G, et al. (2005) Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions. Oncogene 24: 6626-6636.
-
(2005)
Oncogene
, vol.24
, pp. 6626-6636
-
-
Buchholz, M.1
Braun, M.2
Heidenblut, A.3
Kestler, H.A.4
Klöppel, G.5
-
34
-
-
69249228672
-
FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt
-
Pei H, Li L, Fridley BL, Jenkins GD, Kalari KR, et al. (2009) FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt. Cancer Cell 16: 259-266.
-
(2009)
Cancer Cell
, vol.16
, pp. 259-266
-
-
Pei, H.1
Li, L.2
Fridley, B.L.3
Jenkins, G.D.4
Kalari, K.R.5
-
35
-
-
33644550284
-
The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis
-
Yu Y, Davicioni E, Triche TJ, Merlino G, (2006) The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis. Cancer Res 66: 1982-1989.
-
(2006)
Cancer Res
, vol.66
, pp. 1982-1989
-
-
Yu, Y.1
Davicioni, E.2
Triche, T.J.3
Merlino, G.4
-
36
-
-
84866913764
-
Discovery, optimization and validation of an optimal DNA-binding sequence for the Six1 homeodomain transcription factor
-
Liu Y, Nandi S, Martel A, Antoun A, Ioshikhes I, et al. (2012) Discovery, optimization and validation of an optimal DNA-binding sequence for the Six1 homeodomain transcription factor. Nucleic Acids Res.
-
(2012)
Nucleic Acids Res.
-
-
Liu, Y.1
Nandi, S.2
Martel, A.3
Antoun, A.4
Ioshikhes, I.5
-
37
-
-
0036782277
-
Deregulated homeobox gene expression in cancer: cause or consequence?
-
Abate-Shen C, (2002) Deregulated homeobox gene expression in cancer: cause or consequence? Nat Rev Cancer 2: 777-785.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 777-785
-
-
Abate-Shen, C.1
-
38
-
-
60749109846
-
Cell cycle, CDKs and cancer: a changing paradigm
-
Malumbres M, Barbacid M, (2009) Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 9: 153-166.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
39
-
-
79960836823
-
Cyclin D as a therapeutic target in cancer
-
Musgrove EA, Caldon CE, Barraclough J, Stone A, Sutherland RL, (2011) Cyclin D as a therapeutic target in cancer. Nat Rev Cancer 11: 558-572.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 558-572
-
-
Musgrove, E.A.1
Caldon, C.E.2
Barraclough, J.3
Stone, A.4
Sutherland, R.L.5
|