Dermaseptin S4 derivative K4K20S4: A potential candidate for development of a new microbicide contraceptive agent-an in vitro study

European Journal of Contraception and Reproductive Health Care

Volumn 18, Issue 2, 2013, Pages 79-87

  Zaïri, Amira ^a   Tangy, Frédéric ^b   Hani, Khaled ^a  

^a UNIVERSITY OF SOUSSE   (Tunisia)

^b CNRS   (France)

Author keywords

Antimicrobial activity; Antimicrobial peptides; Contraceptive; Dermaseptin S4; Spermicide

Indexed keywords

CONTRACEPTIVE AGENT; DERMASEPTIN; DERMASEPTIN S4 DERIVATIVE; MICROBICIDE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CYTOTOXICITY; FUNGAL STRAIN; HELA CELL; HUMAN; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; VAGINA CONTRACEPTION;

AMPHIBIAN PROTEINS; ANTI-INFECTIVE AGENTS, LOCAL; ANTIMICROBIAL CATIONIC PEPTIDES; FEMALE; HUMANS; MALE; REFERENCE VALUES; SEMEN ANALYSIS; SEXUALLY TRANSMITTED DISEASES; SKIN;

EID: 84875204910     PISSN: 13625187     EISSN: 14730782     Source Type: Journal    
DOI: 10.3109/13625187.2013.769950     Document Type: Article

References (35)

1. Stone A, Jiang S. Microbicides: Stopping HIV at the gate. Lancet 2006; 368: 431-3.
2. Moodley K. Microbicide research in developing countries: Have we given the ethical concerns due consideration? BMC Med Ethics 2007; 19: 8-10.
3. Zaneveld LJD, Anderson RA, Diao XH, et al. Use of mandelic acid condensation polymer (SAMMA), anew antimicrobial contraceptive agent for vaginal prophylaxis. Fertil Steril 2002; 78: 1107-15.
4. Batá rI. State-of-the-art of non-hormonal methods of contraception: II. Chemical barrier contracep tives. Eur JContracept Reprod Health Care 2010; 15: 89-95.
5. Iyer V, Poddar SS. Update on nonoxynol-9 as vaginal spermicide. Eur JContracept Reprod Health Care 2008; 13: 339-50.
6. D' Cruz OJ, Uckun FM. Gel-microemulsions as vaginal spermicides and intravaginal drug delivery vehicles. Contraception 2001; 64: 113-23.
7. Roddy RE, Zekeng L, Ryan KA, et al. Effect of nonoxynol-9 gel on urogenital gonorrhea and chlamydial infection: Arandomized controlled trial. JAMA 2002; 287: 1117-22.
8. Krebs FC, Miller SR, Catalone BJ, et al. Sodium dodecyl sulfate and C31G as microbicidal alternatives to nonoxynol 9: Comparative sensitivity of primary human vaginal keratinocytes. Antimicrob Agents Chemother 2000; 44: 1954-60.
9. Zasloff M. Antimicrobial peptides of multicellular organisms. Nature 2000; 415: 389-95.
10. Ganz T. Defensins: Antimicrobial peptides of innate immunity. Nat Rev Immunol 2003; 3: 710-20.
11. Leher RI, Ganz T. Antimicrobial peptides in mammalian and insect host defence. Curr Opin Immunol 1999; 11: 23-7.
12. Corzo P, Escoubas P, Villages E, et al. Characterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator. Biochem J 2001; 359: 35-45.
13. Mor A, Nguyen V, Delfour A, et al. Isolation, amino acid sequence, and synthesis of dermaseptin, anovel antimicrobial peptide of amphibian skin. Biochemistry 1991; 30: 8824-30.
14. Nicolas P, El Amri C. The dermaseptin superfamily: Agene based combinatorial library of antimicrobial peptides . Biochim Biophys Acta 2009; 1788: 1537-50.
15. Navon-Venezia S, Feder R, Gaidukov L, et al. Antibacterial properties of dermaseptin S 4 derivatives with in vivo activity. Antimicrob Agents Chemother 2002; 46: 689-94.
16. Kustanovich I, Shallev DE, Mikhlin M, et al. Structural requirements for potent versus selective cytotoxicity for antimicrobial dermaseptin S4 derivatives. J Biol Chem 2002; 277: 16941-51.
17. Hernandez C, Mor A, Dagger F. Functional and structural damage in Leishmania mexicana exposed to the cationic peptide dermaseptin. Eur JCell Biol 1999; 59: 414-24.
18. Dagan A, Efron L, Gaidukov L, et al. In vitro antiplasmodium effects of dermaseptin S4 derivatives. Antimicrob Agents Chemother 2002; 46: 1059-66.
19. Coote PJ, Holyoak CD, Bracey D, et al. Inhibitory action of atruncated derivative of the amphibian skin peptide dermaseptin S 3 on Saccharomyces cerevisiae. Antimicrob Agents Chemother 1998; 42: 2160-70.
20. Belaid A, Aouni M, Khelifa R, et al. In vitro antiviral activity of dermaseptins against herpes simplex virus type 1. JMed Virol 2002; 66: 229-34.
21. Lorin C, Saidi H, Belaid A, et al. The antimicrobial peptide dermaseptin S4 inhibits HIV-1 infectivity in vitro. Virology 2005; 334: 264-75.
22. Zairi A, Belaid A, Ghahbiche A, et al. Spermicidal activity of dermaseptins. Contraception 2005; 72: 447-53.
23. Zairi A, Serres C, Tangy F, et al. In vitro spermicidal activity of peptides from amphibian skin: Dermaseptin S4 and derivatives. Bioorg Med Chem 2008; 1: 266-75.
24. World Health Organization, Department of Reproductive Health. Medical eligibility criteria for contraceptive use, 4th edn. Geneva: World Health Organization 2009.
25. Sander FV, Cramer SD. Apractical method for testing the spermicidal action of chemical contraceptives. Hum Fertil 1941; 6: 134-7.
26. Haineault C, Gourde P, Perron S, et al. Thermoreversible gel formulation containing sodium lauryl sulfate as apotential contraceptive device. Biol Reprod 2003; 69: 687-94.
27. Aranha C, Gupta S, Reddey KV. Contraceptive effi cacy of antimicrobial peptide Nisin: In vitro and in vivo studies. Contraception 2004; 69: 333-38.
28. Centola GM. Dose-response effects of gramicidin-D, EDTA, and nonoxynol-9 on sperm motion parameters and acrosome status. Contraception 1998; 58: 35-8.
29. Sutyak K, Anderson RA, Dover SE, et al. Spermicidal activity of the safe natural antimicrobial peptide subtilosin . Infect Dis Obstet Gynecol 2008: 540758.
30. Tiwari P, Singh D, Singh MM. Anti-Trichomonas activity of Sapindus saponins, acandidate for development as microbicidal contraceptive. JAntimicrob Chemother 2008; 62: 526-34.
31. Kumar S, Biswas H, Banerjee S, et al. Evaluation of safety margins of Chenopodium album seed decoction: 14-day subacute toxicity and microbicidal activity studies. Reprod Biol Endocrinol 2011; 9: 102.
32. Jain JK, Li A, Minoo P, et al. The effect of nonoxynol-9 on human endometrium. Contraception 2005; 71: 137-42.
33. Amiche M, Galanth C. Dermaseptins as models for the elucidation of membrane-acting helical amphipathic antimicrobial peptides. Curr Pharm Biotechnol 2011; 12: 1184-93.
34. Paquette DW, Simpson DM, Friden P, et al. Safety and clinical effects of topical histatin gels in humans with experimental gingivitis. JClin Periodontol 2002; 29: 1051-8.
35. Reddy KVR, Yedery RD, Aranha C. Antimicrobial peptides: Premises and promises. Int JAntimicrob Agents 2004; 24: 536-47.