메뉴 건너뛰기




Volumn 17, Issue 4, 2013, Pages 461-472

βIII-Tubulin: Biomarker of taxane resistance or drug target?

Author keywords

III tubulin; Biomarker; Cancer; Chemotherapy; Docetaxel; Drug resistance; Microtubules; Paclitaxel; Taxanes; Therapeutics; Translational studies; TUBB3; Vinorelbine

Indexed keywords

BETA III TUBULIN; BETA TUBULIN; CISPLATIN; DOCETAXEL; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; MESSENGER RNA; NAVELBINE; PACLITAXEL; TAXANE DERIVATIVE; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84875198728     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2013.766170     Document Type: Review
Times cited : (66)

References (84)
  • 1
    • 84862580438 scopus 로고    scopus 로고
    • Tubulins as therapeutic targets in cancer: From bench to bedside
    • Katsetos CD, Draber P. Tubulins as therapeutic targets in cancer: From bench to bedside. Curr Pharm Des 2012;18(19):2778-92
    • (2012) Curr Pharm Des , vol.18 , Issue.19 , pp. 2778-2792
    • Katsetos, C.D.1    Draber, P.2
  • 2
    • 81055139797 scopus 로고    scopus 로고
    • Class III beta-tubulin (TUBB3): More than a biomarker in solid tumors?
    • Mariani M, Shahabi S, Sieber S, et al. Class III beta-tubulin (TUBB3): More than a biomarker in solid tumors? Curr Mol Med 2011;11(9):726-31
    • (2011) Curr Mol Med , vol.11 , Issue.9 , pp. 726-731
    • Mariani, M.1    Shahabi, S.2    Sieber, S.3
  • 3
    • 38549161093 scopus 로고    scopus 로고
    • Is class III beta-tubulin a predictive factor in patients receiving tubulin-binding agents?
    • Seve P, Dumontet C. Is class III beta-tubulin a predictive factor in patients receiving tubulin-binding agents? Lancet Oncol 2008;9(2):168-75
    • (2008) Lancet Oncol , vol.9 , Issue.2 , pp. 168-175
    • Seve, P.1    Dumontet, C.2
  • 4
    • 56749164904 scopus 로고    scopus 로고
    • Tubulin proteomics: Towards breaking the code
    • Verdier-Pinard P, Pasquier E, Xiao H, et al. Tubulin proteomics: Towards breaking the code. Anal Biochem 2009;384(2):197-206
    • (2009) Anal Biochem , vol.384 , Issue.2 , pp. 197-206
    • Verdier-Pinard, P.1    Pasquier, E.2    Xiao, H.3
  • 5
    • 0024326922 scopus 로고
    • An immunohistochemical study of neuropeptides and neuronal cytoskeletal proteins in the neuroepithelial component of a spontaneous murine ovarian teratoma. Primitive neuroepithelium displays immunoreactivity for neuropeptides and neuron-associated beta-tubulin isotype
    • Caccamo DV, Herman MM, Frankfurter A, et al. An immunohistochemical study of neuropeptides and neuronal cytoskeletal proteins in the neuroepithelial component of a spontaneous murine ovarian teratoma. Primitive neuroepithelium displays immunoreactivity for neuropeptides and neuron-associated beta-tubulin isotype. Am J Pathol 1989;135(5):801-13
    • (1989) Am J Pathol , vol.135 , Issue.5 , pp. 801-813
    • Caccamo, D.V.1    Herman, M.M.2    Frankfurter, A.3
  • 6
    • 67449164713 scopus 로고    scopus 로고
    • Effects of FSH on testicular mRNA transcript levels in the hypogonadal mouse
    • Abel MH, Baban D, Lee S, et al. Effects of FSH on testicular mRNA transcript levels in the hypogonadal mouse. J Mol Endocrinol 2009;42(4):291-303
    • (2009) J Mol Endocrinol , vol.42 , Issue.4 , pp. 291-303
    • Abel, M.H.1    Baban, D.2    Lee, S.3
  • 8
    • 37449001322 scopus 로고    scopus 로고
    • How do microtubule-targeted drugs work? An overview
    • Jordan MA, Kamath K. How do microtubule-targeted drugs work? An overview. Curr Cancer Drug Targets 2007;7(8):730-42
    • (2007) Curr Cancer Drug Targets , vol.7 , Issue.8 , pp. 730-742
    • Jordan, M.A.1    Kamath, K.2
  • 9
    • 0030940117 scopus 로고    scopus 로고
    • Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified beta-tubulin isotypes
    • Derry WB, Wilson L, Khan IA, et al. Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified beta-tubulin isotypes. Biochemistry 1997;36(12):3554-62
    • (1997) Biochemistry , vol.36 , Issue.12 , pp. 3554-3562
    • Derry, W.B.1    Wilson, L.2    Khan, I.A.3
  • 10
    • 19944430079 scopus 로고    scopus 로고
    • Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients
    • Mozzetti S, Ferlini C, Concolino P, et al. Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients. Clin Cancer Res 2005;11(1):298-305
    • (2005) Clin Cancer Res , vol.11 , Issue.1 , pp. 298-305
    • Mozzetti, S.1    Ferlini, C.2    Concolino, P.3
  • 11
    • 0030931827 scopus 로고    scopus 로고
    • Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes
    • Kavallaris M, Kuo DY, Burkhart CA, et al. Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes. J Clin Invest 1997;100(5):1282-93
    • (1997) J Clin Invest , vol.100 , Issue.5 , pp. 1282-1293
    • Kavallaris, M.1    Kuo, D.Y.2    Burkhart, C.A.3
  • 12
    • 35148854099 scopus 로고    scopus 로고
    • Class III beta-tubulin mediates sensitivity to chemotherapeutic drugs in non small cell lung cancer
    • Gan PP, Pasquier E, Kavallaris M. Class III beta-tubulin mediates sensitivity to chemotherapeutic drugs in non small cell lung cancer. Cancer Res 2007;67(19):9356-63
    • (2007) Cancer Res , vol.67 , Issue.19 , pp. 9356-9363
    • Gan, P.P.1    Pasquier, E.2    Kavallaris, M.3
  • 13
    • 77953750777 scopus 로고    scopus 로고
    • BetaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer
    • McCarroll JA, Gan PP, Liu M, Kavallaris M. betaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer. Cancer Res 2010;70(12):4995-5003
    • (2010) Cancer Res , vol.70 , Issue.12 , pp. 4995-5003
    • McCarroll, J.A.1    Gan, P.P.2    Liu, M.3    Kavallaris, M.4
  • 14
    • 38349049063 scopus 로고    scopus 로고
    • Hypoxia induces class III beta-tubulin gene expression by HIF-1alpha binding to its 3¢ flanking region
    • Raspaglio G, Filippetti F, Prislei S, et al. Hypoxia induces class III beta-tubulin gene expression by HIF-1alpha binding to its 3¢ flanking region. Gene 2008;409(1-2):100-8
    • (2008) Gene , vol.409 , Issue.1-2 , pp. 100-108
    • Raspaglio, G.1    Filippetti, F.2    Prislei, S.3
  • 15
    • 77955048655 scopus 로고    scopus 로고
    • HuR regulates beta-tubulin isotype expression in ovarian cancer
    • Raspaglio G, De Maria I, Filippetti F, et al. HuR regulates beta-tubulin isotype expression in ovarian cancer. Cancer Res 2010;70(14):5891-900
    • (2010) Cancer Res , vol.70 , Issue.14 , pp. 5891-5900
    • Raspaglio, G.1    De Maria, I.2    Filippetti, F.3
  • 16
    • 57749093352 scopus 로고    scopus 로고
    • Molecular mechanisms of patupilone resistance
    • Mozzetti S, Iantomasi R, De Maria I, et al. Molecular mechanisms of patupilone resistance. Cancer Res 2008;68(24):10197-204
    • (2008) Cancer Res , vol.68 , Issue.24 , pp. 10197-10204
    • Mozzetti, S.1    Iantomasi, R.2    De Maria, I.3
  • 17
    • 84858340202 scopus 로고    scopus 로고
    • Differential in vitro sensitivity to patupilone versus paclitaxel in uterine and ovarian carcinosarcoma cell lines is linked to tubulin-beta-iii expression
    • Carrara L, Guzzo F, Roque DM, et al. Differential in vitro sensitivity to patupilone versus paclitaxel in uterine and ovarian carcinosarcoma cell lines is linked to tubulin-beta-III expression. Gynecol Oncol 2012;125(1):231-6
    • (2012) Gynecol Oncol , vol.125 , Issue.1 , pp. 231-236
    • Carrara, L.1    Guzzo, F.2    Roque, D.M.3
  • 18
    • 79959649836 scopus 로고    scopus 로고
    • Specific beta-tubulin isotypes can functionally enhance or diminish epothilone b sensitivity in non-small cell lung cancer cells
    • Gan PP, McCarroll JA, Byrne FL, et al. Specific beta-tubulin isotypes can functionally enhance or diminish epothilone B sensitivity in non-small cell lung cancer cells. PLoS ONE 2011;6(6):e21717
    • (2011) PLoS ONE , vol.6 , Issue.6
    • Gan, P.P.1    McCarroll, J.A.2    Byrne, F.L.3
  • 19
    • 77649287402 scopus 로고    scopus 로고
    • Expression of class III beta-tubulin correlates with unfavorable survival outcome in patients with resected non-small cell lung cancer
    • Koh Y, Jang B, Han SW, et al. Expression of class III beta-tubulin correlates with unfavorable survival outcome in patients with resected non-small cell lung cancer. J Thorac Oncol 2010;5(3):320-5
    • (2010) J Thorac Oncol , vol.5 , Issue.3 , pp. 320-325
    • Koh, Y.1    Jang, B.2    Han, S.W.3
  • 20
    • 30344437279 scopus 로고    scopus 로고
    • Class III beta-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel
    • Seve P, Mackey J, Isaac S, et al. Class III beta-tubulin expression in tumor cells predicts response and outcome in patients with non-small cell lung cancer receiving paclitaxel. Mol Cancer Ther 2005;4(12):2001-7
    • (2005) Mol Cancer Ther , vol.4 , Issue.12 , pp. 2001-2007
    • Seve, P.1    Mackey, J.2    Isaac, S.3
  • 21
    • 14544302690 scopus 로고    scopus 로고
    • Expression of class III beta tubulin in non-small cell lung cancer is correlated with resistance to taxane chemotherapy
    • Dumontet C, Isaac S, Souquet PJ, et al. Expression of class III beta tubulin in non-small cell lung cancer is correlated with resistance to taxane chemotherapy. Bull Cancer 2005;92(2):E25-30
    • (2005) Bull Cancer , vol.92 , Issue.2
    • Dumontet, C.1    Isaac, S.2    Souquet, P.J.3
  • 22
    • 23044435044 scopus 로고    scopus 로고
    • Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy
    • Seve P, Isaac S, Tredan O, et al. Expression of class III {beta}-tubulin is predictive of patient outcome in patients with non-small cell lung cancer receiving vinorelbine-based chemotherapy. Clin Cancer Res 2005;11(15):5481-6
    • (2005) Clin Cancer Res , vol.11 , Issue.15 , pp. 5481-5486
    • Seve, P.1    Isaac, S.2    Tredan, O.3
  • 23
    • 84855220707 scopus 로고    scopus 로고
    • Mutation and expression of multiple treatment response-related genes in a population with locally advanced non-small cell lung cancer
    • Lu HY, Su D, Pan XD, et al. Mutation and expression of multiple treatment response-related genes in a population with locally advanced non-small cell lung cancer. Oncol Lett 2012;3(2):415-20
    • (2012) Oncol Lett , vol.3 , Issue.2 , pp. 415-420
    • Lu, H.Y.1    Su, D.2    Pan, X.D.3
  • 24
    • 84862742698 scopus 로고    scopus 로고
    • High tubb3 expression an independent prognostic marker in patients with early non-small cell lung cancer treated by preoperative chemotherapy is regulated by k-ras signaling pathway
    • Levallet G, Bergot E, Antoine M, et al. High TUBB3 expression, an independent prognostic marker in patients with early non-small cell lung cancer treated by preoperative chemotherapy, is regulated by K-Ras signaling pathway. Mol Cancer Ther 2012;11(5):1203-13
    • (2012) Mol Cancer Ther , vol.11 , Issue.5 , pp. 1203-1213
    • Levallet, G.1    Bergot, E.2    Antoine, M.3
  • 25
    • 61749103813 scopus 로고    scopus 로고
    • Class III beta-tubulin expression in tumor cells is correlated with resistance to docetaxel in patients with completely resected non-small-cell lung cancer
    • Hayashi Y, Kuriyama H, Umezu H, et al. Class III beta-tubulin expression in tumor cells is correlated with resistance to docetaxel in patients with completely resected non-small-cell lung cancer. Intern Med 2009;48(4):203-8
    • (2009) Intern Med , vol.48 , Issue.4 , pp. 203-208
    • Hayashi, Y.1    Kuriyama, H.2    Umezu, H.3
  • 26
    • 84879416338 scopus 로고    scopus 로고
    • The role of beta-III-tubulin in non-small cell lung cancer patients treated by taxane-based chemotherapy
    • Kaira K, Takahashi T, Murakami H, et al. The role of beta-III-tubulin in non-small cell lung cancer patients treated by taxane-based chemotherapy. Int J Clin Oncol 2012
    • (2012) Int J Clin Oncol
    • Kaira, K.1    Takahashi, T.2    Murakami, H.3
  • 27
    • 84862820442 scopus 로고    scopus 로고
    • Association between class III beta-tubulin expression and response to paclitaxelvinorelbine-based chemotherapy for non-small cell lung cancer: A meta-analysis
    • Zhang HL, Ruan L, Zheng LM, et al. Association between class III beta-tubulin expression and response to paclitaxel/vinorelbine-based chemotherapy for non-small cell lung cancer: A meta-analysis. Lung Cancer 2012;77(1):9-15
    • (2012) Lung Cancer , vol.77 , Issue.1 , pp. 9-15
    • Zhang, H.L.1    Ruan, L.2    Zheng, L.M.3
  • 28
    • 33847416564 scopus 로고    scopus 로고
    • Class III beta-tubulin expression and benefit from adjuvant cisplatin/vinorelbine chemotherapy in operable non-small cell lung cancer: Analysis of NCIC JBR.10
    • Seve P, Lai R, Ding K, et al. Class III beta-tubulin expression and benefit from adjuvant cisplatin/vinorelbine chemotherapy in operable non-small cell lung cancer: Analysis of NCIC JBR.10. Clin Cancer Res 2007;13(3):994-9
    • (2007) Clin Cancer Res , vol.13 , Issue.3 , pp. 994-999
    • Seve, P.1    Lai, R.2    Ding, K.3
  • 29
    • 79956115415 scopus 로고    scopus 로고
    • Is class iii beta-tubulin a true predictive marker of sensitivity to vinorelbine in non-small cell lung cancer? Chemosensitivity data evidence
    • Hirai Y, Yoshimasu T, Oura S, et al. Is class III beta-tubulin a true predictive marker of sensitivity to vinorelbine in non-small cell lung cancer? Chemosensitivity data evidence. Anticancer Res 2011;31(3):999-1005
    • (2011) Anticancer Res , vol.31 , Issue.3 , pp. 999-1005
    • Hirai, Y.1    Yoshimasu, T.2    Oura, S.3
  • 30
    • 84255206496 scopus 로고    scopus 로고
    • Cross-validation study of class iii beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: Analysis of four randomized trials
    • Reiman T, Lai R, Veillard AS, et al. Cross-validation study of class III beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: Analysis of four randomized trials. Ann Oncol 2012;23(1):86-93
    • (2012) Ann Oncol , vol.23 , Issue.1 , pp. 86-93
    • Reiman, T.1    Lai, R.2    Veillard, A.S.3
  • 31
    • 52149089030 scopus 로고    scopus 로고
    • Expression of excision repair cross-complementation group 1 and class III beta-tubulin predict survival after chemotherapy for completely resected non-small cell lung cancer
    • Okuda K, Sasaki H, Dumontet C, et al. Expression of excision repair cross-complementation group 1 and class III beta-tubulin predict survival after chemotherapy for completely resected non-small cell lung cancer. Lung Cancer 2008;62(1):105-12
    • (2008) Lung Cancer , vol.62 , Issue.1 , pp. 105-112
    • Okuda, K.1    Sasaki, H.2    Dumontet, C.3
  • 32
    • 77952544071 scopus 로고    scopus 로고
    • The prognostic significance of ercc1 brca1 xrcc1 and beta-iii-tubulin expression in patients with non-small cell lung cancer treated by platinum- and taxane-based neoadjuvant chemotherapy and surgical resection
    • Kang CH, Jang BG, Kim DW, et al. The prognostic significance of ERCC1, BRCA1, XRCC1, and beta-III-tubulin expression in patients with non-small cell lung cancer treated by platinum- and taxane-based neoadjuvant chemotherapy and surgical resection. Lung Cancer 2010;68(3):478-83
    • (2010) Lung Cancer , vol.68 , Issue.3 , pp. 478-483
    • Kang, C.H.1    Jang, B.G.2    Kim, D.W.3
  • 33
    • 67349275022 scopus 로고    scopus 로고
    • Expression of ERCC1 and class III beta-tubulin in non-small cell lung cancer patients treated with carboplatin and paclitaxel
    • Azuma K, Sasada T, Kawahara A, et al. Expression of ERCC1 and class III beta-tubulin in non-small cell lung cancer patients treated with carboplatin and paclitaxel. Lung Cancer 2009;64(3):326-33
    • (2009) Lung Cancer , vol.64 , Issue.3 , pp. 326-333
    • Azuma, K.1    Sasada, T.2    Kawahara, A.3
  • 34
    • 67349119484 scopus 로고    scopus 로고
    • Expression of ERCC1 and class III beta-tubulin in non-small cell lung cancer patients treated with a combination of cisplatin/docetaxel and concurrent thoracic irradiation
    • Azuma K, Sasada T, Kawahara A, et al. Expression of ERCC1 and class III beta-tubulin in non-small cell lung cancer patients treated with a combination of cisplatin/docetaxel and concurrent thoracic irradiation. Cancer Chemother Pharmacol 2009;64(3):565-73
    • (2009) Cancer Chemother Pharmacol , vol.64 , Issue.3 , pp. 565-573
    • Azuma, K.1    Sasada, T.2    Kawahara, A.3
  • 35
    • 71049134390 scopus 로고    scopus 로고
    • Expression of ERCC1 and class III beta tubulin for predicting effect of carboplatin/paclitaxel in patients with advanced inoperable non-small cell lung cancer
    • Ikeda S, Takabe K, Suzuki K. Expression of ERCC1 and class III beta tubulin for predicting effect of carboplatin/paclitaxel in patients with advanced inoperable non-small cell lung cancer. Pathol Int 2009;59(12):863-7
    • (2009) Pathol Int , vol.59 , Issue.12 , pp. 863-867
    • Ikeda, S.1    Takabe, K.2    Suzuki, K.3
  • 36
    • 84856577873 scopus 로고    scopus 로고
    • RT-PCR Versus Immunohistochemistry For Correlation And Quantification Of ERCC1 BRCA1 TUBB3 And RRM1 In NSCLC
    • Vilmar A, Garcia-Foncillas J, Huarriz M, et al. RT-PCR versus immunohistochemistry for correlation and quantification of ERCC1, BRCA1, TUBB3 and RRM1 in NSCLC. Lung Cancer 2012;75(3):306-12
    • (2012) Lung Cancer , vol.75 , Issue.3 , pp. 306-312
    • Vilmar, A.1    Garcia-Foncillas, J.2    Huarriz, M.3
  • 37
    • 33646717530 scopus 로고    scopus 로고
    • Class III beta-tubulin overexpression is a marker of poor clinical outcome in advanced ovarian cancer patients
    • Ferrandina G, Zannoni GF, Martinelli E, et al. Class III beta-tubulin overexpression is a marker of poor clinical outcome in advanced ovarian cancer patients. Clin Cancer Res 2006;12(9):2774-9
    • (2006) Clin Cancer Res , vol.12 , Issue.9 , pp. 2774-2779
    • Ferrandina, G.1    Zannoni, G.F.2    Martinelli, E.3
  • 38
    • 34248378221 scopus 로고    scopus 로고
    • Expression of beta-tubulin isotypes in human primary ovarian carcinoma
    • Ohishi Y, Oda Y, Basaki Y, et al. Expression of beta-tubulin isotypes in human primary ovarian carcinoma. Gynecol Oncol 2007;105(3):586-92
    • (2007) Gynecol Oncol , vol.105 , Issue.3 , pp. 586-592
    • Ohishi, Y.1    Oda, Y.2    Basaki, Y.3
  • 39
    • 41349121211 scopus 로고    scopus 로고
    • Taxol resistance among the different histological subtypes of ovarian cancer may be associated with the expression of class III beta-tubulin
    • Umezu T, Shibata K, Kajiyama H, et al. Taxol resistance among the different histological subtypes of ovarian cancer may be associated with the expression of class III beta-tubulin. Int J Gynecol Pathol 2008;27(2):207-12
    • (2008) Int J Gynecol Pathol , vol.27 , Issue.2 , pp. 207-212
    • Umezu, T.1    Shibata, K.2    Kajiyama, H.3
  • 40
    • 66649102458 scopus 로고    scopus 로고
    • Stathmin and tubulin expression and survival of ovarian cancer patients receiving platinum treatment with and without paclitaxel
    • Su D, Smith SM, Preti M, et al. Stathmin and tubulin expression and survival of ovarian cancer patients receiving platinum treatment with and without paclitaxel. Cancer 2009;115(11):2453-63
    • (2009) Cancer , vol.115 , Issue.11 , pp. 2453-2463
    • Su, D.1    Smith, S.M.2    Preti, M.3
  • 41
    • 79959353409 scopus 로고    scopus 로고
    • Class iii beta-tubulin expression in advanced-stage serous ovarian carcinoma effusions is associated with poor survival and primary chemoresistance
    • Hetland TE, Hellesylt E, Florenes VA, et al. Class III beta-tubulin expression in advanced-stage serous ovarian carcinoma effusions is associated with poor survival and primary chemoresistance. Hum Pathol 2011;42(7):1019-26
    • (2011) Hum Pathol , vol.42 , Issue.7 , pp. 1019-1026
    • Hetland, T.E.1    Hellesylt, E.2    Florenes, V.A.3
  • 42
    • 63149086677 scopus 로고    scopus 로고
    • Overexpression of class III beta-tubulin predicts good response to taxane-based chemotherapy in ovarian clear cell adenocarcinoma
    • Aoki D, Oda Y, Hattori S, et al. Overexpression of class III beta-tubulin predicts good response to taxane-based chemotherapy in ovarian clear cell adenocarcinoma. Clin Cancer Res 2009;15(4):1473-80
    • (2009) Clin Cancer Res , vol.15 , Issue.4 , pp. 1473-1480
    • Aoki, D.1    Oda, Y.2    Hattori, S.3
  • 43
    • 84155184238 scopus 로고    scopus 로고
    • Class III beta-tubulin and the cytoskeletal gateway for drug resistance in ovarian cancer
    • De Donato M, Mariani M, Petrella L, et al. Class III beta-tubulin and the cytoskeletal gateway for drug resistance in ovarian cancer. J Cell Physiol 2012;227(3):1034-41
    • (2012) J Cell Physiol , vol.227 , Issue.3 , pp. 1034-1041
    • De Donato, M.1    Mariani, M.2    Petrella, L.3
  • 44
    • 79251476882 scopus 로고    scopus 로고
    • The mir-200 family controls beta-tubulin iii expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients
    • Leskela S, Leandro-Garcia LJ, Mendiola M, et al. The miR-200 family controls beta-tubulin III expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients. Endocr Relat Cancer 2011;18(1):85-95
    • (2011) Endocr Relat Cancer , vol.18 , Issue.1 , pp. 85-95
    • Leskela, S.1    Leandro-Garcia, L.J.2    Mendiola, M.3
  • 45
    • 48149100125 scopus 로고    scopus 로고
    • Epigenetic modification is involved in aberrant expression of class III beta-tubulin, TUBB3, in ovarian cancer cells
    • Izutsu N, Maesawa C, Shibazaki M, et al. Epigenetic modification is involved in aberrant expression of class III beta-tubulin, TUBB3, in ovarian cancer cells. Int J Oncol 2008;32(6):1227-35
    • (2008) Int J Oncol , vol.32 , Issue.6 , pp. 1227-1235
    • Izutsu, N.1    Maesawa, C.2    Shibazaki, M.3
  • 46
    • 2542422890 scopus 로고    scopus 로고
    • Systematic review of taxane-containing versus non-taxane-containing regimens for adjuvant and neoadjuvant treatment of early breast cancer
    • Nowak AK, Wilcken NR, Stockler MR, et al. Systematic review of taxane-containing versus non-taxane-containing regimens for adjuvant and neoadjuvant treatment of early breast cancer. Lancet Oncol 2004;5(6):372-80
    • (2004) Lancet Oncol , vol.5 , Issue.6 , pp. 372-380
    • Nowak, A.K.1    Wilcken, N.R.2    Stockler, M.R.3
  • 47
    • 30344455579 scopus 로고    scopus 로고
    • Biomarkers predictive for clinical efficacy of taxol-based chemotherapy in advanced breast cancer
    • Paradiso A, Mangia A, Chiriatti A, et al. Biomarkers predictive for clinical efficacy of taxol-based chemotherapy in advanced breast cancer. Ann Oncol 2005;16(Suppl 4):iv14-19
    • (2005) Ann Oncol , vol.16 , Issue.SUPPL. 4
    • Paradiso, A.1    Mangia, A.2    Chiriatti, A.3
  • 48
    • 79954644097 scopus 로고    scopus 로고
    • Prognostic utility of beta-tubulin isotype iii and correlations with other molecular and clinicopathological variables in patients with early breast cancer: A translational hellenic cooperative oncology group (hecog) study
    • Pentheroudakis G, Batistatou A, Kalogeras KT, et al. Prognostic utility of beta-tubulin isotype III and correlations with other molecular and clinicopathological variables in patients with early breast cancer: A translational Hellenic Cooperative Oncology Group (HeCOG) study. Breast Cancer Res Treat 2011;127(1):179-93
    • (2011) Breast Cancer Res Treat , vol.127 , Issue.1 , pp. 179-193
    • Pentheroudakis, G.1    Batistatou, A.2    Kalogeras, K.T.3
  • 49
    • 51649107171 scopus 로고    scopus 로고
    • Class III beta-tubulin isotype predicts response in advanced breast cancer patients randomly treated either with single-agent doxorubicin or docetaxel
    • Galmarini CM, Treilleux I, Cardoso F, et al. Class III beta-tubulin isotype predicts response in advanced breast cancer patients randomly treated either with single-agent doxorubicin or docetaxel. Clin Cancer Res 2008;14(14):4511-16
    • (2008) Clin Cancer Res , vol.14 , Issue.14 , pp. 4511-4516
    • Galmarini, C.M.1    Treilleux, I.2    Cardoso, F.3
  • 50
    • 84866646922 scopus 로고    scopus 로고
    • Overexpression of class iii beta tubulin and amplified her2 gene predict good response to paclitaxel and trastuzumab therapy
    • Jung M, Koo JS, Moon YW, et al. Overexpression of class III beta tubulin and amplified HER2 gene predict good response to paclitaxel and trastuzumab therapy. PLoS One 2012;7(9):e45127
    • (2012) PLoS One , vol.7 , Issue.9
    • Jung, M.1    Koo, J.S.2    Moon, Y.W.3
  • 51
    • 84864880464 scopus 로고    scopus 로고
    • Expression of beta-tubulin III and survivin in advance stage breast cancer correlates with chemotherapeutic effects of docetaxel
    • Yuan SF, Zhu LJ, Zheng WE, et al. Expression of beta-tubulin III and survivin in advance stage breast cancer correlates with chemotherapeutic effects of docetaxel. Asian Pac J Cancer Prev 2012;13(1):361-5
    • (2012) Asian Pac J Cancer Prev , vol.13 , Issue.1 , pp. 361-365
    • Yuan, S.F.1    Zhu, L.J.2    Zheng, W.E.3
  • 52
    • 84856430333 scopus 로고    scopus 로고
    • Measuring beta-tubulin iii bcl-2 and ercc1 improves pathological complete remission predictive accuracy in breast cancer
    • Chen X, Wu J, Lu H, et al. Measuring beta-tubulin III, Bcl-2, and ERCC1 improves pathological complete remission predictive accuracy in breast cancer. Cancer Sci 2012;103(2):262-8
    • (2012) Cancer Sci , vol.103 , Issue.2 , pp. 262-268
    • Chen, X.1    Wu, J.2    Lu, H.3
  • 53
    • 67650133664 scopus 로고    scopus 로고
    • Beta 3-tubulin is induced by estradiol in human breast carcinoma cells through an estrogen-receptor dependent pathway
    • Saussede-Aim J, Matera EL, Ferlini C, Dumontet C. Beta 3-tubulin is induced by estradiol in human breast carcinoma cells through an estrogen-receptor dependent pathway. Cell Motil Cytoskeleton 2009;66(7):378-88
    • (2009) Cell Motil Cytoskeleton , vol.66 , Issue.7 , pp. 378-388
    • Saussede-Aim, J.1    Matera, E.L.2    Ferlini, C.3    Dumontet, C.4
  • 54
    • 18544367472 scopus 로고    scopus 로고
    • Current status and future prospects of chemotherapy for metastatic gastric cancer: A review
    • Ohtsu A. Current status and future prospects of chemotherapy for metastatic gastric cancer: A review. Gastric Cancer 2005;8(2):95-102
    • (2005) Gastric Cancer , vol.8 , Issue.2 , pp. 95-102
    • Ohtsu, A.1
  • 55
    • 33746851344 scopus 로고    scopus 로고
    • Clinical significance of class III beta-tubulin expression and its predictive value for resistance to docetaxel-based chemotherapy in gastric cancer
    • Urano N, Fujiwara Y, Doki Y, et al. Clinical significance of class III beta-tubulin expression and its predictive value for resistance to docetaxel-based chemotherapy in gastric cancer. Int J Oncol 2006;28(2):375-81
    • (2006) Int J Oncol , vol.28 , Issue.2 , pp. 375-381
    • Urano, N.1    Fujiwara, Y.2    Doki, Y.3
  • 56
    • 84875194496 scopus 로고    scopus 로고
    • Serum levels of biii-tubulin correlate with clinical outcome in chinese patients with advanced gastric cancer receiving first-line paclitaxel plus capecitabine
    • Yu J, Gao J, Lu Z, et al. Serum levels of bIII-Tubulin correlate with clinical outcome in Chinese patients with advanced gastric cancer receiving first-line paclitaxel plus capecitabine. Med Oncol 2012;29(5):3029-34
    • (2012) Med Oncol , vol.29 , Issue.5 , pp. 3029-3034
    • Yu, J.1    Gao, J.2    Lu, Z.3
  • 57
    • 79955945042 scopus 로고    scopus 로고
    • Thymidine phosphorylase/beta-tubulin III expressions predict the response in Chinese advanced gastric cancer patients receiving first-line capecitabine plus paclitaxel
    • Gao J, Lu M, Yu JW, et al. Thymidine phosphorylase/beta-tubulin III expressions predict the response in Chinese advanced gastric cancer patients receiving first-line capecitabine plus paclitaxel. BMC Cancer 2011;11:177
    • (2011) BMC Cancer , vol.11 , pp. 177
    • Gao, J.1    Lu, M.2    Yu, J.W.3
  • 58
    • 84863628234 scopus 로고    scopus 로고
    • Overexpression of beta III-tubulin and survivin associated with drug resistance to docetaxel-based chemotherapy in advanced gastric cancer
    • Zheng WE, Chen H, Yuan SF, et al. Overexpression of beta III-tubulin and survivin associated with drug resistance to docetaxel-based chemotherapy in advanced gastric cancer. J BUON 2012;17(2):284-90
    • (2012) J BUON , vol.17 , Issue.2 , pp. 284-290
    • Zheng, W.E.1    Chen, H.2    Yuan, S.F.3
  • 59
    • 65949090282 scopus 로고    scopus 로고
    • Expression of class III beta-tubulin in colorectal carcinomas: An immunohistochemical study using TU-20 & TuJ-1 antibody
    • Jirasek T, Cipro S, Musilova A, et al. Expression of class III beta-tubulin in colorectal carcinomas: An immunohistochemical study using TU-20 & TuJ-1 antibody. Indian J Med Res 2009;129(1):89-94
    • (2009) Indian J Med Res , vol.129 , Issue.1 , pp. 89-94
    • Jirasek, T.1    Cipro, S.2    Musilova, A.3
  • 60
    • 84861168754 scopus 로고    scopus 로고
    • Gender influences the class iii and v beta-tubulin ability to predict poor outcome in colorectal cancer
    • Mariani M, Zannoni GF, Sioletic S, et al. Gender influences the Class III and V beta-tubulin ability to predict poor outcome in colorectal cancer. Clin Cancer Res 2012;18(10):2964-75
    • (2012) Clin Cancer Res , vol.18 , Issue.10 , pp. 2964-2975
    • Mariani, M.1    Zannoni, G.F.2    Sioletic, S.3
  • 61
    • 0034744673 scopus 로고    scopus 로고
    • A common promoter variant in the cytochrome P450c17alpha (CYP17) gene is associated with bioavailability testosterone levels and bone size in men
    • Zmuda JM, Cauley JA, Kuller LH, Ferrell RE. A common promoter variant in the cytochrome P450c17alpha (CYP17) gene is associated with bioavailability testosterone levels and bone size in men. J Bone Miner Res 2001;16(5):911-17
    • (2001) J Bone Miner Res , vol.16 , Issue.5 , pp. 911-917
    • Zmuda, J.M.1    Cauley, J.A.2    Kuller, L.H.3    Ferrell, R.E.4
  • 62
    • 79551500582 scopus 로고    scopus 로고
    • Expression of CYP19 and CYP17 is associated with leg length, weight, and BMI
    • Yousefi M, Karmaus W, Mudd LM, et al. Expression of CYP19 and CYP17 is associated with leg length, weight, and BMI. Obesity (Silver Spring) 2011;19(2):436-41
    • (2011) Obesity (Silver Spring) , vol.19 , Issue.2 , pp. 436-441
    • Yousefi, M.1    Karmaus, W.2    Mudd, L.M.3
  • 63
    • 70249124131 scopus 로고    scopus 로고
    • Increased expression of class III beta-tubulin in castration-resistant human prostate cancer
    • Terry S, Ploussard G, Allory Y, et al. Increased expression of class III beta-tubulin in castration-resistant human prostate cancer. Br J Cancer 2009;101(6):951-6
    • (2009) Br J Cancer , vol.101 , Issue.6 , pp. 951-956
    • Terry, S.1    Ploussard, G.2    Allory, Y.3
  • 64
    • 84870529082 scopus 로고    scopus 로고
    • Docetaxel maintains its cytotoxic activity under hypoxic conditions in prostate cancer cells
    • Forde JC, Perry AS, Brennan K, et al. Docetaxel maintains its cytotoxic activity under hypoxic conditions in prostate cancer cells. Urol Oncol 2012;30(6):912-19
    • (2012) Urol Oncol , vol.30 , Issue.6 , pp. 912-919
    • Forde, J.C.1    Perry, A.S.2    Brennan, K.3
  • 65
    • 80052577789 scopus 로고    scopus 로고
    • Expression of hypoxia inducible factor-1 alpha in matched hormone naive and castrate-resistant prostate cancer specimens
    • Elsberger B, Lankston L, Orange C, et al. Expression of hypoxia inducible factor-1 alpha in matched hormone naive and castrate-resistant prostate cancer specimens. Cancer Biomark 2010;8(1):1-9
    • (2010) Cancer Biomark , vol.8 , Issue.1 , pp. 1-9
    • Elsberger, B.1    Lankston, L.2    Orange, C.3
  • 66
    • 78649296410 scopus 로고    scopus 로고
    • Beta-tubulin III expression in prostate cancer
    • Egevad L, Valdman A, Wiklund NP, et al. Beta-tubulin III expression in prostate cancer. Scand J Urol Nephrol 2010;44(6):371-7
    • (2010) Scand J Urol Nephrol , vol.44 , Issue.6 , pp. 371-377
    • Egevad, L.1    Valdman, A.2    Wiklund, N.P.3
  • 67
    • 78549257475 scopus 로고    scopus 로고
    • Class iii beta-tubulin expression predicts prostate tumor aggressiveness and patient response to docetaxel-based chemotherapy
    • Ploussard G, Terry S, Maille P, et al. Class III beta-tubulin expression predicts prostate tumor aggressiveness and patient response to docetaxel-based chemotherapy. Cancer Res 2010;70(22):9253-64
    • (2010) Cancer Res , vol.70 , Issue.22 , pp. 9253-9264
    • Ploussard, G.1    Terry, S.2    Maille, P.3
  • 68
    • 33846366042 scopus 로고    scopus 로고
    • Expression of class III beta tubulin in cervical cancer patients administered preoperative radiochemotherapy: Correlation with response to treatment and clinical outcome
    • Ferrandina G, Martinelli E, Zannoni GF, et al. Expression of class III beta tubulin in cervical cancer patients administered preoperative radiochemotherapy: Correlation with response to treatment and clinical outcome. Gynecol Oncol 2007;104(2):326-30
    • (2007) Gynecol Oncol , vol.104 , Issue.2 , pp. 326-330
    • Ferrandina, G.1    Martinelli, E.2    Zannoni, G.F.3
  • 69
    • 69449099543 scopus 로고    scopus 로고
    • Class III beta-tubulin, but not ERCC1, is a strong predictive and prognostic marker in locally advanced head and neck squamous cell carcinoma
    • Koh Y, Kim TM, Jeon YK, et al. Class III beta-tubulin, but not ERCC1, is a strong predictive and prognostic marker in locally advanced head and neck squamous cell carcinoma. Ann Oncol 2009;20(8):1414-19
    • (2009) Ann Oncol , vol.20 , Issue.8 , pp. 1414-1419
    • Koh, Y.1    Kim, T.M.2    Jeon, Y.K.3
  • 70
    • 34247403761 scopus 로고    scopus 로고
    • Class III beta-tubulin is a marker of paclitaxel resistance in carcinomas of unknown primary site
    • Seve P, Reiman T, Lai R, et al. Class III beta-tubulin is a marker of paclitaxel resistance in carcinomas of unknown primary site. Cancer Chemother Pharmacol 2007;60(1):27-34
    • (2007) Cancer Chemother Pharmacol , vol.60 , Issue.1 , pp. 27-34
    • Seve, P.1    Reiman, T.2    Lai, R.3
  • 71
    • 42549102569 scopus 로고    scopus 로고
    • Protein abundance of class III beta-tubulin but not Delta2-alpha-tubulin or tau is related to paclitaxel response in carcinomas of unknown primary site
    • Seve P, Reiman T, Isaac S, et al. Protein abundance of class III beta-tubulin but not Delta2-alpha-tubulin or tau is related to paclitaxel response in carcinomas of unknown primary site. Anticancer Res 2008;28(2B):1161-7
    • (2008) Anticancer Res , vol.28 , Issue.2 B , pp. 1161-1167
    • Seve, P.1    Reiman, T.2    Isaac, S.3
  • 72
    • 79951770288 scopus 로고    scopus 로고
    • Expression of excision repair cross-complementation group 1, breast cancer susceptibility 1, and beta III-tubulin in thymic epithelial tumors
    • Kaira K, Serizawa M, Koh Y, et al. Expression of excision repair cross-complementation group 1, breast cancer susceptibility 1, and beta III-tubulin in thymic epithelial tumors. J Thorac Oncol 2011;6(3):606-13
    • (2011) J Thorac Oncol , vol.6 , Issue.3 , pp. 606-613
    • Kaira, K.1    Serizawa, M.2    Koh, Y.3
  • 73
    • 70350070389 scopus 로고    scopus 로고
    • Expression of tubulin, p53, ki67, receptors for estrogen, and progesterone in endometrial cancer
    • Zhu C, Luo J, Shi H, et al. Expression of tubulin, p53, ki67, receptors for estrogen, and progesterone in endometrial cancer. Eur J Gynaecol Oncol 2009;30(5):514-17
    • (2009) Eur J Gynaecol Oncol , vol.30 , Issue.5 , pp. 514-517
    • Zhu, C.1    Luo, J.2    Shi, H.3
  • 74
    • 83055169906 scopus 로고    scopus 로고
    • Expression of ERCC1, p53, and class III beta-tubulin do not reveal chemoresistance in endometrial cancer: Results from an immunohistochemical study
    • Vandenput I, Capoen A, Coenegrachts L, et al. Expression of ERCC1, p53, and class III beta-tubulin do not reveal chemoresistance in endometrial cancer: Results from an immunohistochemical study. Int J Gynecol Cancer 2011;21(6):1071-7
    • (2011) Int J Gynecol Cancer , vol.21 , Issue.6 , pp. 1071-1077
    • Vandenput, I.1    Capoen, A.2    Coenegrachts, L.3
  • 75
    • 84873090658 scopus 로고    scopus 로고
    • Updates in therapy for uterine serous carcinoma
    • Roque DM, Santin AD. Updates in therapy for uterine serous carcinoma. Curr Opin Obstet Gynecol 2013;25(1):29-37
    • (2013) Curr Opin Obstet Gynecol , vol.25 , Issue.1 , pp. 29-37
    • Roque, D.M.1    Santin, A.D.2
  • 76
    • 67349102267 scopus 로고    scopus 로고
    • Loss of class III beta-tubulin induced by histone deacetylation is associated with chemosensitivity to paclitaxel in malignant melanoma cells
    • Akasaka K, Maesawa C, Shibazaki M, et al. Loss of class III beta-tubulin induced by histone deacetylation is associated with chemosensitivity to paclitaxel in malignant melanoma cells. J Invest Dermatol 2009;129(6):1516-26
    • (2009) J Invest Dermatol , vol.129 , Issue.6 , pp. 1516-1526
    • Akasaka, K.1    Maesawa, C.2    Shibazaki, M.3
  • 77
    • 77955177246 scopus 로고    scopus 로고
    • Immunohistochemical study of HER2 and TUBB3 proteins in extramammary Paget disease
    • Miyamoto A, Akasaka K, Oikawa H, et al. Immunohistochemical study of HER2 and TUBB3 proteins in extramammary Paget disease. Am J Dermatopathol 2010;32(6):578-85
    • (2010) Am J Dermatopathol , vol.32 , Issue.6 , pp. 578-585
    • Miyamoto, A.1    Akasaka, K.2    Oikawa, H.3
  • 78
    • 70350370033 scopus 로고    scopus 로고
    • Aberrant expression of class III beta-tubulin in basal cell carcinoma of the skin
    • Ishida M, Kushima R, Okabe H. Aberrant expression of class III beta-tubulin in basal cell carcinoma of the skin. Oncol Rep 2009;22(4):733-7
    • (2009) Oncol Rep , vol.22 , Issue.4 , pp. 733-737
    • Ishida, M.1    Kushima, R.2    Okabe, H.3
  • 79
    • 77951800247 scopus 로고    scopus 로고
    • Class III beta-tubulin shows unique expression patterns in a variety of neoplastic and non-neoplastic lymphoproliferative disorders
    • Yoon SO, Kim WY, Go H, et al. Class III beta-tubulin shows unique expression patterns in a variety of neoplastic and non-neoplastic lymphoproliferative disorders. Am J Surg Pathol 2010;34(5):645-55
    • (2010) Am J Surg Pathol , vol.34 , Issue.5 , pp. 645-655
    • Yoon, S.O.1    Kim, W.Y.2    Go, H.3
  • 80
    • 77951136560 scopus 로고    scopus 로고
    • Tumoral and tissue-specific expression of the major human beta-tubulin isotypes
    • Leandro-Garcia LJ, Leskela S, Landa I, et al. Tumoral and tissue-specific expression of the major human beta-tubulin isotypes. Cytoskeleton (Hoboken) 2010;67(4):214-23
    • (2010) Cytoskeleton (Hoboken) , vol.67 , Issue.4 , pp. 214-223
    • Leandro-Garcia, L.J.1    Leskela, S.2    Landa, I.3
  • 81
    • 84862510018 scopus 로고    scopus 로고
    • Novel drugs targeting microtubules: The role of epothilones
    • Ferrandina G, Mariani M, Andreoli M, et al. Novel drugs targeting microtubules: The role of epothilones. Curr Pharm Des 2012;18(19):2793-803
    • (2012) Curr Pharm Des , vol.18 , Issue.19 , pp. 2793-2803
    • Ferrandina, G.1    Mariani, M.2    Andreoli, M.3
  • 82
    • 58149503624 scopus 로고    scopus 로고
    • Ixabepilone: Targeting beta III-tubulin expression in taxane-resistant malignancies
    • Dumontet C, Jordan MA, Lee FF. Ixabepilone: Targeting beta III-tubulin expression in taxane-resistant malignancies. Mol Cancer Ther 2009;8(1):17-25
    • (2009) Mol Cancer Ther , vol.8 , Issue.1 , pp. 17-25
    • Dumontet, C.1    Jordan, M.A.2    Lee, F.F.3
  • 83
    • 33747827890 scopus 로고    scopus 로고
    • Hedgehog signal transduction: Signal integration and cross talk in development and cancer
    • Riobo NA, Lu K, Emerson Jr. C.P. Hedgehog signal transduction: Signal integration and cross talk in development and cancer. Cell Cycle 2006;5(15):1612-15
    • (2006) Cell Cycle , vol.5 , Issue.15 , pp. 1612-1615
    • Riobo, N.A.1    Lu, K.2    Emerson Jr., C.P.3
  • 84
    • 84868482683 scopus 로고    scopus 로고
    • Gli family transcription factors are drivers of patupilone resistance in ovarian cancer
    • Mozzetti S, Martinelli E, Raspaglio G, et al Gli family transcription factors are drivers of patupilone resistance in ovarian cancer. Biochem Pharmacol 2012;84(11):1409-18
    • (2012) Biochem Pharmacol , vol.84 , Issue.11 , pp. 1409-1418
    • Mozzetti, S.1    Martinelli, E.2    Raspaglio, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.