New clinical pathways for keratoconus

Eye (Basingstoke)

Volumn 27, Issue 3, 2013, Pages 329-339

  Gore, D M ^a   Shortt, A J ^a   Allan, B D ^a  

^a MOORFIELDS EYE HOSPITAL   (United Kingdom)

Author keywords

crosslinking; intracorneal ring; intraocular lens; keratoconus; meta analysis; review

Indexed keywords

ATOPIC KERATOCONJUNCTIVITIS; CLINICAL PATHWAY; CONTACT LENS; CORNEA CELL; CORNEA IMPLANT; CORNEA STROMA; CORNEA SURGERY; CORNEAL ENDOTHELIAL CELL LOSS; CYTOTOXICITY; DISEASE COURSE; ENDOTHELIUM CELL; HUMAN; KERATOCONUS; KERATOMETRY; KERATOPLASTY; OPTICAL COHERENCE TOMOGRAPHY; PHAKIC INTRAOCULAR LENS; PHOTOREFRACTIVE KERATECTOMY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REFRACTIVE SURGERY; REVIEW; SYSTEMATIC REVIEW;

EID: 84875182752     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/eye.2012.257     Document Type: Review

References (76)

1. Pearson A, Soneji B, Sarvananthan N. Does ethnic origin influence the incidence or severity of keratoconus? Eye 2000; 14: 625-628
2. Lass JH, Lembach RG, Park SB, Hom DL, Fritz ME, Svilar GM et al. Clinical management of keratoconus. A multicenter analysis. Ophthalmology 1990; 97(4): 433-445. (Pubitemid 20108448)
3. Rebenitsch RL, Kymes SM, Walline JJ, Gordon MO. The lifetime economic burden of keratoconus: A decision analysis using a Markov model. Am J Ophthalmol 2011; 151(5): 768-773.
4. Kelly TL, Williams KA, Coster DJ. for the Australian Corneal Graft Registry. Corneal transplantation for keratoconus: A registry study. Arch Ophthalmol 2011; 129(6): 691-697.
5. Kelly TL, Coster DJ, Williams KA. Repeat penetrating corneal transplantation in patients with keratoconus. Ophthalmology 2011; 118(8): 1538-1542.
6. Reinhart WJ, Musch DC, Jacobs DS, Lee WB, Kaufman SC, Shtein RM. Deep anterior lamellar keratoplasty as an alternative to penetrating keratoplasty. Ophthalmology 2011; 118(1): 209-218.
7. Borderie VM, Sandali O, Bullet J, Gaujoux T, Touzeau O, Laroche L. Long-term results of deep anterior lamellar versus penetrating keratoplasty. Ophthalmology 2012; 119(2): 249-255.
8. Jones MNA, Armitage WJ, Ayliffe W, Larkin DF, Kaye SB. on behalf of the NHSBT Ocular Tissue Advisory Group and Contributing Ophthalmologists (OTAG Audit Study 5). Penetrating and deep anterior lamellar keratoplasty for keratoconus: A comparison of graft outcomes in the United Kingdom. Invest Ophthalmol Vis Sci 2009; 50(12): 5625-5629.
9. Colin J, Velou S. Current surgical options for keratoconus. J Cataract Refract Surg 2003; 29(2): 379-386. (Pubitemid 36278559)
10. Roe RH, Lass JH, Brown GC, Brown MM. The value-based medicine comparative effectiveness and cost-effectiveness of penetrating keratoplasty for keratoconus. Cornea 2008; 27(9): 1001-1007.
11. Koo TS, Finkelstein E, Tan D, Mehta JS. Incremental costutility analysis of deep anterior lamellar keratoplasty compared with penetrating keratoplasty for the treatment of keratoconus. Am J Ophthalmol 2011; 152(1): 40-42.
12. Yildiz EH, Cohen EJ, Virdi AS, Hammersmith KM, Laibson PR, Rapuano CJ. Quality of life in keratoconus patients after penetrating keratoplasty. Am J Ophthalmol 2010; 149(3): 416-422.
13. Kymes SM, Walline JJ, Zadnik K, Sterling J, Gordon MO. Changes in the quality-of-life of people with keratoconus. Am J Ophthalmol 2008; 145(4): 611-617.
14. O'Brart DPS, Chan E, Samaras K, Patel P, Shah SP. A randomised, prospective study to investigate the efficacy of riboflavin/ultraviolet A (370 nm) corneal collagen crosslinkage to halt the progression of keratoconus. Br J Ophthalmol 2011; 95(11): 1519-1524.
15. Fraser CG, Fogarty Y. Interpreting laboratory results. BMJ 1989; 298(6689): 1659-1660. (Pubitemid 19157763)
16. Szalai E, Berta A, Hassan Z, Mo'dis Jr., L. Reliability and repeatability of swept-source Fourier-domain optical coherence tomography and Scheimpflug imaging in keratoconus. J Cataract Refract Surg 2012; 38(3): 485-494.
17. Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-ainduced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 2003; 135(5): 620-627. (Pubitemid 36457967)
18. Hersh PS, Greenstein SA, Fry KL. Corneal collagen crosslinking for keratoconus and corneal ectasia: one-year results. J Cataract Refract Surg 2011; 37(1): 149-160.
19. Caporossi A, Mazzotta C, Baiocchi S, Caporossi T. Longterm results of riboflavin ultraviolet a corneal collagen cross-linking for keratoconus in Italy: The Siena eye cross study. Am J Ophthalmol 2010; 149(4): 585-593.
20. Vinciguerra P, Albé E, Frueh BE, Trazza S, Epstein D. Two-year corneal cross-linking results in patients younger than 18 years with documented progressive keratoconus. AJOPHT 2012; 23: 1-7.
21. Wittig-Silva C, Whiting M, Lamoureux E, Lindsay RG, Sullivan LJ, Snibson GR. A randomized controlled trial of corneal collagen cross-linking in progressive keratoconus: preliminary results. J Refract Surg 2008; 24(7): S720-S725.
22. Koller T, Mrochen M, Seiler T. Complication and failure rates after corneal crosslinking. J Cataract Refract Surg 2009; 35(8): 1358-1362.
23. Snibson GR. Collagen cross-linking: A new treatment paradigm in corneal disease - a review. Clin Exp Ophthalmol 2010; 38(2): 141-153.
24. Spoerl E, Mrochen M, Sliney D, Trokel S, Seiler T. Safety of UVA-riboflavin cross-linking of the cornea. Cornea 2007; 26(4): 385-389. (Pubitemid 46684375)
25. Kymionis GD, Portaliou DM, Diakonis VF, Kounis GA, Panagopoulou SI, Grentzelos MA. Corneal collagen cross-linking with riboflavin and ultraviolet-A irradiation in patients with thin corneas. Am J Ophthalmol 2012; 153(1): 24-28.
26. Gokhale NS. Corneal endothelial damage after collagen cross-linking treatment. Cornea 2011; 30(12): 1495-1498.
27. Wollensak G, Spo? rl E, Reber F, Pillunat L, Funk R. Corneal endothelial cytotoxicity of riboflavin/UVA treatment in vitro. Ophthalmic Res 2003; 35(6): 324-328. (Pubitemid 38032509)
28. Hafezi F, Mrochen M, Iseli HP, Seiler T. Collagen crosslinking with ultraviolet-A and hypoosmolar riboflavin solution in thin corneas. J Cataract Refract Surg ASCRS and ESCRS 2009; 35(4): 621-624.
29. Raiskup F, Ki-ner A, Spoerl E, Pillunat LE. Hornhautvernetzung mit hypoosmolarer Riboflavin-Lo?sung beim Keratokonus mit du? nner Hornhaut [Corneal cross-linking with hypo-osmolar riboflavin solution for keratoconus with thin corneas]. Ophthalmologe 2011; 108(9): 846-851.
30. Schumacher S, Oeftiger L, Mrochen M. Equivalence of biomechanical changes induced by rapid and standard corneal cross-linking, using riboflavin and ultraviolet radiation. Invest Ophthalmol Vis Sci 2011; 52(12): 9048-9052.
31. Kanellopoulos J. Long term results of a prospective randomized bilateral eye comparison trial of higher fluence, shorter duration ultraviolet A radiation, and riboflavin collagen cross linking for progressive keratoconus. Clin Ophthalmol 2012; 6: 97-101.
32. Zhang Y, Sukthankar P, Tomich JM, Conrad GW. Effect of the synthetic NC-1059 peptide on diffusion of riboflavin across an intact corneal epithelium. Invest Ophthalmol Vis Sci 2012; 53(6): 2620-2629.
33. Leccisotti A, Islam T. Transepithelial corneal collagen crosslinking in keratoconus. J Refract Surg 2010; 26(12): 942-948.
34. Filippello M, Stagni E, O'Brart D. Transepithelial corneal collagen crosslinking: Bilateral study. J Cataract Refract Surg 2012; 38(2): 283-291.
35. Koppen C,Wouters K, Mathysen D, Rozema J, Tassignon MJ. Refractive and topographic results of benzalkonium chloride-assisted transepithelial crosslinking. J Cataract Refract Surg 2012; 38(6): 1000-1005.
36. Stojanovic A, Chen X, Jin N, Zhang T, Stojanovic F, Raeder S et al. Safety and efficacy of epithelium-on corneal collagen cross-linking using a multifactorial approach to achieve proper stromal riboflavin saturation. J Ophthalmol 2012; 2012: 1-8.
37. Tuft SJ, Moodaley LC, Gregory WM, Davison CR, Buckley RJ. Prognostic factors for the progression of keratoconus. Ophthalmology 1994; 101(3): 439-447. (Pubitemid 24100567)
38. Gordon MO, Steger-May K, Szczotka-Flynn L, Riley C, Joslin CE, Weissman BA et al. Baseline factors predictive of incident penetrating keratoplasty in keratoconus. Am J Ophthalmol 2006; 142(6): 923-930.
39. McMahon TT, Edrington TB, Szczotka-Flynn L, Olafsson HE, Davis LJ, Schechtman KB et al. Longitudinal changes in corneal curvature in keratoconus. Cornea 2006; 25(3): 296-305.
40. Barnett M, Mannis MJ. Contact lenses in the management of keratoconus. Cornea 2011; 30(12): 1510-1516.
41. Ozbek Z, Cohen EJ. Use of intralimbal rigid gas-permeable lenses for pellucid marginal degeneration, keratoconus, and after penetrating keratoplasty. Eye Contact Lens 2006; 32(1): 33-36. (Pubitemid 43189092)
42. Pecego M, Barnett M, Mannis MJ, Durbin-Johnson B. Jupiter scleral lenses: The UC Davis Eye Center experience. Eye Contact Lens 2012; 38(3): 179-182.
43. Pin? ero DP, Alio JL, Kady El B, Coskunseven E, Morbelli H, Uceda-Montanes A et al. Refractive and aberrometric outcomes of intracorneal ring segments for keratoconus: mechanical versus femtosecond-assisted procedures. Ophthalmology 2009; 116(9): 1675-1687.
44. Kubaloglu A, Cinar Y, Sari ES, Koytak A, Ozdemir B, Ozertu? rk Y. Comparison of 2 intrastromal corneal ring segment models in the management of keratoconus. J Cataract Refract Surg 2010; 36(6): 978-985.
45. Rabinowitz YS, Li X, Ignacio TS, Maguen E. INTACS inserts using the femtosecond laser compared to the mechanical spreader in the treatment of keratoconus. J Refract Surg 2006; 22(8): 764-771. (Pubitemid 44595121)
46. Kubaloglu A, Sari ES, Cinar Y, Cingu K, Koytak A, Coşkun E et al. Comparison of mechanical and femtosecond laser tunnel creation for intrastromal corneal ring segment implantation in keratoconus: prospective randomized clinical trial. J Cataract Refract Surg 2010; 36(9): 1556-1561.
47. Coskunseven E, Kymionis GD, Tsiklis NS, Atun S, Arslan E, Siganos CS et al. Complications of intrastromal corneal ring segment implantation using a femtosecond laser for channel creation: A survey of 850 eyes with keratoconus. Acta Ophthalmol 2011; 89(1): 54-57.
48. Coskunseven E, Kymionis GD, Tsiklis NS, Atun S, Arslan E, Jankov MR et al. One-year results of intrastromal corneal ring segment implantation (KeraRing) using femtosecond laser in patients with keratoconus. Am J Ophthalmol 2008; 145(5): 775-779.
49. Shabayek MH, Alio JL. Intrastromal corneal ring segment implantation by femtosecond laser for keratoconus correction. Ophthalmology 2007; 114(9): 1643-1652. (Pubitemid 47332655)
50. Haddad W, Fadlallah A, Dirani A, Rami El H, Fahd D, Khanafer D et al. Comparison of 2 types of intrastromal corneal ring segments for keratoconus. J Cartaract Refract Surg 2012; 38(7): 1214-1221.
51. Alio JL, Shabayek MH, Artola A. Intracorneal ring segments for keratoconus correction: Long-term follow-up. J Cartaract Refract Surg 2006; 32(6): 978-985. (Pubitemid 43949464)
52. Coskunseven E, Jankov MR, Hafezi F, Atun S, Arslan E, Kymionis GD. Effect of treatment sequence in combined intrastromal corneal rings and corneal collagen crosslinking for keratoconus. J Cataract Refract Surg 2009; 35(12): 2084-2091.
53. Saelens IEY, Bartels MC, Bleyen I, Van Rij G. Refractive, topographic, and visual outcomes of same-day corneal cross-linking with ferrara intracorneal ring segments in patients with progressive keratoconus. Cornea 2011; 30(12): 1406-1408.
54. El-Raggal TM. Sequential versus concurrent KERARINGS insertion and corneal collagen cross-linking for keratoconus. Br J Ophthalmol 2011; 95(1): 37-41.
55. Chan CCK, Sharma M, Wachler BSB. Effect of inferiorsegment Intacs with and without C3-R on keratoconus. J Cataract Refract Surg 2007; 33(1): 75-80. (Pubitemid 44959708)
56. Ertan A, Karacal H, Kamburoglu G. Refractive and topographic results of transepithelial cross-linking treatment in eyes with intacs. Cornea 2009; 28(7): 719-723.
57. Kato N, Toda I, Kawakita T, Sakai C, Tsubota K. Topography-guided conductive keratoplasty: Treatment for advanced keratoconus. Am J Ophthalmol 2010; 150(4): 481-489.
58. Kymionis GD, Kontadakis GA, Kounis GA, Portaliou DM, Karavitaki AE, Magarakis M et al. Simultaneous topography-guided PRK followed by corneal collagen cross-linking for keratoconus. J Refract Surg 2009; 25(9): S807-S811.
59. Kanellopoulos AJ, Binder PS. Collagen cross-linking (CCL) with sequential topography-guided PRK: A temporizing alternative for keratoconus to penetrating keratoplasty. Cornea 2007; 26(7): 891-895. (Pubitemid 47220571)
60. Kanellopoulos AJ. Comparison of sequential vs same-day simultaneous collagen cross-linking and topographyguided PRK for treatment of keratoconus. J Refract Surg 2009; 25(9): S812-S818.
61. Alfonso JF, Palacios A, Montés-Micó R. Myopic phakic STAAR collamer posterior chamber intraocular lenses for keratoconus. J Refract Surg 2008; 24(9): 867-874.
62. Kamiya K, Shimizu K, Kobashi H, Komatsu M, Nakamura A, Nakamura Tet al. Clinical outcomes of posterior chamber toric phakic intraocular lens implantation for the correction of high myopic astigmatism in eyes with keratoconus: 6-month follow-up. Graefes Arch Clin Exp Ophthalmol 2011; 249(7): 1073-1080.
63. Izquierdo L, Henriquez MA, McCarthy M. Artiflex phakic intraocular lens implantation after corneal collagen cross-linking in keratoconic eyes. J Refract Surg 2011; 27(7): 482-487.
64. Sedaghat M, Ansari-Astaneh M-R, Zarei-Ghanavati M, Davis SW, Sikder S. Artisan iris-supported phakic IOL implantation in patients with keratoconus: A review of 16 eyes. J Refract Surg 2011; 27(7): 489-493.
65. Alfonso JF, Fernández-Vega L, Lisa C, Fernandes P, González-Méijome JM, Montés-Micó R. Collagen copolymer toric posterior chamber phakic intraocular lens in eyes with keratoconus. J Cataract Refract Surg 2010; 36(6): 906-916.
66. Kato N, Toda I, Hori-Komai Y, Sakai C, Arai H, Tsubota K. Phakic intraocular lens for keratoconus. Ophthalmology 2011; 118(3): 605-605.
67. Alfonso JF, Lisa C, Abdelhamid A, Montés-Micó R, Poo-López A, Ferrer-Blasco T. Posterior chamber phakic intraocular lenses after penetrating keratoplasty. J Cataract Refract Surg 2009; 35(7): 1166-1173.
68. Kohnen T, Kook D, Morral M, Gu? ell JL. Phakic intraocular lenses: part 2: Results and complications. J Cataract Refract Surg 2010; 36(12): 2168-2194.
69. Pesando PM, Ghiringhello MP, Di Meglio G, Fanton G. Posterior chamber phakic intraocular lens (ICL) for hyperopia: Ten-year follow-up. J Cataract Refract Surg 2007; 33(9): 1579-1584.
70. Edelhauser HF, Sanders DR, Azar R, Lamielle H. ICL in Treatment of Myopia Study Group. Corneal endothelial assessment after ICL implantation. J Cataract Refract Surg 2004; 30(3): 576-583. (Pubitemid 38429632)
71. Alfonso JF, Lisa C, Fernández-Vega L, Madrid-Costa D, Poo-López A, Montés-Micó R. Intrastromal corneal ring segments and posterior chamber phakic intraocular lens implantation for keratoconus correction. J Cataract Refract Surg 2011; 37(4): 706-713.
72. Moshirfar M, Fenzl CR, Meyer JJ, Neuffer MC, Espandar L, Mifflin MD. Simultaneous and sequential implantation of Intacs and Verisyse phakic intraocular lens for refractive improvement in keratectasia. Cornea 2011; 30(2): 158-163.
73. Cakir H, Utine CA. Combined Kerarings and Artisan/Artiflex IOLs in keratectasia. J Refract Surg 2010; 27(2): 119-126.
74. El-Raggal TM, Abdel Fattah AA. Sequential Intacs and Verisyse phakic intraocular lens for refractive improvement in keratoconic eyes. J Cataract Refract Surg 2007; 33(6): 966-970. (Pubitemid 46771069)
75. Huang D, Schallhorn SC, Sugar A, Farjo AA, Majmudar PA, Trattler WB et al. Phakic intraocular lens implantation for the correction of myopia. Ophthalmology 2009; 116(11): 2244-2258.
76. Raiskup-Wolf F, Hoyer A, Spoerl E, Pillunat LE. Collagen crosslinking with riboflavin and ultraviolet-A light in keratoconus: Long-term results. J Cataract Refract Surg 2008; 34(5): 796-801. (Pubitemid 351615507)