-
1
-
-
79251501644
-
The hippo pathway in biological control and cancer development
-
Chan SW, Lim CJ, Chen L, Chong YF, Huang C, et al. (2011) The hippo pathway in biological control and cancer development, J. Cell. Physiol 226: 928-939.
-
(2011)
J. Cell. Physiol
, vol.226
, pp. 928-939
-
-
Chan, S.W.1
Lim, C.J.2
Chen, L.3
Chong, Y.F.4
Huang, C.5
-
2
-
-
78650885839
-
Mst1/2 signalling to Yap: gatekeeper for liver size and tumour development
-
Avruch J, Zhou D, Fitamant J, Bardeesy N, (2011) Mst1/2 signalling to Yap: gatekeeper for liver size and tumour development. Br. J. Cancer 104: 24-32.
-
(2011)
Br. J. Cancer
, vol.104
, pp. 24-32
-
-
Avruch, J.1
Zhou, D.2
Fitamant, J.3
Bardeesy, N.4
-
3
-
-
0029788972
-
The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain
-
Creasy CL, Ambrose DM, Chernoff J, (1996) The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain. J. Biol. Chem 271: 21049-21053.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 21049-21053
-
-
Creasy, C.L.1
Ambrose, D.M.2
Chernoff, J.3
-
4
-
-
0035964190
-
Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation, Proc
-
Ura S, Masuyama N, Graves JD, Gotoh Y, (2001) Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation, Proc. Natl. Acad. Sci. U S A 98: 10148-10153.
-
(2001)
Natl. Acad. Sci. U S A
, vol.98
, pp. 10148-10153
-
-
Ura, S.1
Masuyama, N.2
Graves, J.D.3
Gotoh, Y.4
-
5
-
-
0037073794
-
Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis
-
Lin Y, Khokhlatchev A, Figeys D, Avruch J, (2002) Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis. J. Biol. Chem 277: 47991-48001.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 47991-48001
-
-
Lin, Y.1
Khokhlatchev, A.2
Figeys, D.3
Avruch, J.4
-
6
-
-
0038293152
-
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase
-
Cheung WL, Ajiro K, Samejima K, Kloc M, Cheung P, et al. (2003) Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell 113: 507-517.
-
(2003)
Cell
, vol.113
, pp. 507-517
-
-
Cheung, W.L.1
Ajiro, K.2
Samejima, K.3
Kloc, M.4
Cheung, P.5
-
7
-
-
33646934067
-
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
-
Lehtinen MK, Yuan Z, Boag PR, Yang Y, Villen J, et al. (2006) A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125: 987-1001.
-
(2006)
Cell
, vol.125
, pp. 987-1001
-
-
Lehtinen, M.K.1
Yuan, Z.2
Boag, P.R.3
Yang, Y.4
Villen, J.5
-
8
-
-
65649149752
-
Regulation of neuronal cell death by MST1-FOXO1 signaling
-
Yuan Z, Lehtinen MK, Merlo P, Villen J, Gygi S, et al. (2009) Regulation of neuronal cell death by MST1-FOXO1 signaling. J. Biol. Chem 284: 11285-11292.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 11285-11292
-
-
Yuan, Z.1
Lehtinen, M.K.2
Merlo, P.3
Villen, J.4
Gygi, S.5
-
9
-
-
35649004861
-
Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation
-
Jang SW, Yang SJ, Srinivasan S, Ye K, (2007) Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation. J. Biol.Chem 282: 30836-30844.
-
(2007)
J. Biol.Chem
, vol.282
, pp. 30836-30844
-
-
Jang, S.W.1
Yang, S.J.2
Srinivasan, S.3
Ye, K.4
-
10
-
-
23744458034
-
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
-
Huang J, Wu S, Barrera J, Matthews K, Pan D, (2005) The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 122: 421-434.
-
(2005)
Cell
, vol.122
, pp. 421-434
-
-
Huang, J.1
Wu, S.2
Barrera, J.3
Matthews, K.4
Pan, D.5
-
11
-
-
16444373346
-
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
-
Chan EH, Nousiainen M, Chalamalasetty RB, Schafer A, Nigg EA, et al. (2005) The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene 24: 2076-2086.
-
(2005)
Oncogene
, vol.24
, pp. 2076-2086
-
-
Chan, E.H.1
Nousiainen, M.2
Chalamalasetty, R.B.3
Schafer, A.4
Nigg, E.A.5
-
12
-
-
77949909616
-
c-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82
-
Bi W, Xiao L, Jia Y, Wu J, Xie Q, et al. (2010) c-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82. J. Biol. Chem 285: 6259-6264.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 6259-6264
-
-
Bi, W.1
Xiao, L.2
Jia, Y.3
Wu, J.4
Xie, Q.5
-
13
-
-
59849083562
-
Phosphorylation of cardiac troponin I by mammalian sterile 20-like kinase 1
-
You B, Yan G, Zhang Z, Yan L, Li J, et al. (2009) Phosphorylation of cardiac troponin I by mammalian sterile 20-like kinase 1. Biochem. J 418: 93-101.
-
(2009)
Biochem. J
, vol.418
, pp. 93-101
-
-
You, B.1
Yan, G.2
Zhang, Z.3
Yan, L.4
Li, J.5
-
14
-
-
0035805593
-
Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis
-
Graves JD, Draves KE, Gotoh Y, Krebs EG, Clark EA, (2001) Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis. J. Biol. Chem 276: 14909-14915.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 14909-14915
-
-
Graves, J.D.1
Draves, K.E.2
Gotoh, Y.3
Krebs, E.G.4
Clark, E.A.5
-
15
-
-
0037044808
-
Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation
-
Glantschnig H, Roda GA, Reszka AA, (2002) Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation. J. Biol. Chem 277: 42987-42996.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 42987-42996
-
-
Glantschnig, H.1
Roda, G.A.2
Reszka, A.A.3
-
16
-
-
3242794878
-
Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
-
Praskova M, Khoklatchev A, Ortiz-Vega S, Avruch J, (2004) Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras. Biochem. J. 381: 453-462.
-
(2004)
Biochem. J
, vol.381
, pp. 453-462
-
-
Praskova, M.1
Khoklatchev, A.2
Ortiz-Vega, S.3
Avruch, J.4
-
17
-
-
34047250808
-
RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network
-
Guo C, Tommasi S, Liu L, Yee JK, Dammann R, et al. (2007) RASSF1A is part of a complex similar to the Drosophila Hippo/Salvador/Lats tumor-suppressor network. Curr. Biol 17: 700-705.
-
(2007)
Curr. Biol
, vol.17
, pp. 700-705
-
-
Guo, C.1
Tommasi, S.2
Liu, L.3
Yee, J.K.4
Dammann, R.5
-
18
-
-
69249217720
-
RASSF2 associates with and stabilizes the proapoptotic kinase MST2
-
Cooper WN, Hesson LB, Matallanas D, Dallol A, von Kriegsheim A, et al. (2009) RASSF2 associates with and stabilizes the proapoptotic kinase MST2. Oncogene 28: 2988-2998.
-
(2009)
Oncogene
, vol.28
, pp. 2988-2998
-
-
Cooper, W.N.1
Hesson, L.B.2
Matallanas, D.3
Dallol, A.4
von Kriegsheim, A.5
-
19
-
-
39849097306
-
The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals
-
Zeng Q, Hong W, (2008) The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals. Cancer. Cell 13: 188-192.
-
(2008)
Cancer. Cell
, vol.13
, pp. 188-192
-
-
Zeng, Q.1
Hong, W.2
-
20
-
-
77952562926
-
Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis
-
Qiao M, Wang Y, Xu X, Lu J, Dong Y, et al. (2010) Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis. Mol. Cell 38: 512--523.
-
(2010)
Mol. Cell
, vol.38
, pp. 512-523
-
-
Qiao, M.1
Wang, Y.2
Xu, X.3
Lu, J.4
Dong, Y.5
-
21
-
-
42049107717
-
Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells
-
Ren A, Yan G, You B, Sun J, (2008) Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells. Cancer. Res 68: 2266-2274.
-
(2008)
Cancer. Res
, vol.68
, pp. 2266-2274
-
-
Ren, A.1
Yan, G.2
You, B.3
Sun, J.4
-
22
-
-
79953211893
-
The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2
-
Guo C, Zhang X, Pfeifer GP, (2011) The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2. J. Biol. Chem 286: 6253-6261.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 6253-6261
-
-
Guo, C.1
Zhang, X.2
Pfeifer, G.P.3
-
23
-
-
85047691556
-
Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy
-
Yamamoto S, Yang G, Zablocki D, Liu J, Hong C, et al. (2003) Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy. J. Clin. Invest 111: 1463-1474.
-
(2003)
J. Clin. Invest
, vol.111
, pp. 1463-1474
-
-
Yamamoto, S.1
Yang, G.2
Zablocki, D.3
Liu, J.4
Hong, C.5
-
24
-
-
34248353095
-
Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction
-
Odashima M, Usui S, Takagi H, Hong C, Liu J, et al. (2007) Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction. Circ. Res 100: 1344-1352.
-
(2007)
Circ. Res
, vol.100
, pp. 1344-1352
-
-
Odashima, M.1
Usui, S.2
Takagi, H.3
Hong, C.4
Liu, J.5
-
25
-
-
33748361572
-
FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1
-
Sun J, Yan G, Ren A, You B, Liao JK, (2006) FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1. Circ. Res 99: 468-476.
-
(2006)
Circ. Res
, vol.99
, pp. 468-476
-
-
Sun, J.1
Yan, G.2
Ren, A.3
You, B.4
Liao, J.K.5
-
26
-
-
38049134474
-
Identification of the prosurvival activity of nerve growth factor on cardiac myocytes
-
Caporali A, Sala-Newby GB, Meloni M, Graiani G, Pani E, et al. (2008) Identification of the prosurvival activity of nerve growth factor on cardiac myocytes. Cell Death and Differentiation 15: 299-311.
-
(2008)
Cell Death and Differentiation
, vol.15
, pp. 299-311
-
-
Caporali, A.1
Sala-Newby, G.B.2
Meloni, M.3
Graiani, G.4
Pani, E.5
-
27
-
-
0034726714
-
Identification of the NAD(+)-binding fold of glyceraldehyde-3-phosphate dehydrogenase as a novel RNA-binding domain, Biochem
-
Nagy E, Henics T, Eckert M, Miseta A, Lightowlers RN, et al. (2000) Identification of the NAD(+)-binding fold of glyceraldehyde-3-phosphate dehydrogenase as a novel RNA-binding domain, Biochem. Biophys. Res. Commun 275: 253-260.
-
(2000)
Biophys. Res. Commun
, vol.275
, pp. 253-260
-
-
Nagy, E.1
Henics, T.2
Eckert, M.3
Miseta, A.4
Lightowlers, R.N.5
-
28
-
-
84864300195
-
GAPDH: A common enzyme with uncommon functions, Clin
-
Nicholls C, Li H, Liu JP, (2012) GAPDH: A common enzyme with uncommon functions, Clin. Exp. Pharmacol. Physiol 39: 674-9.
-
(2012)
Exp. Pharmacol. Physiol
, vol.39
, pp. 674-679
-
-
Nicholls, C.1
Li, H.2
Liu, J.P.3
-
29
-
-
0034776026
-
Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes
-
Yamamoto S, Seta K, Morisco C, Vatner SF, Sadoshima J, (2001) Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes. J Mol. Cell. Cardiol 33: 1829-1848.
-
(2001)
J Mol. Cell. Cardiol
, vol.33
, pp. 1829-1848
-
-
Yamamoto, S.1
Seta, K.2
Morisco, C.3
Vatner, S.F.4
Sadoshima, J.5
-
30
-
-
22144477159
-
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding
-
Hara MR, Agrawal N, Kim SF, Cascio MB, Fujimuro M, et al. (2005) S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nat. Cell. Biol 7: 665-674.
-
(2005)
Nat. Cell. Biol
, vol.7
, pp. 665-674
-
-
Hara, M.R.1
Agrawal, N.2
Kim, S.F.3
Cascio, M.B.4
Fujimuro, M.5
-
31
-
-
46649101876
-
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis
-
Sen N, Hara MR, Kornberg MD, Cascio MB, Bae BI, et al. (2008) Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis. Nat. Cell. Biol 10: 866-873.
-
(2008)
Nat. Cell. Biol
, vol.10
, pp. 866-873
-
-
Sen, N.1
Hara, M.R.2
Kornberg, M.D.3
Cascio, M.B.4
Bae, B.I.5
-
32
-
-
77949879018
-
Glyceraldehyde-3-phosphate dehydrogenase in retinal microvasculature: implications for the development and progression of diabetic retinopathy
-
Madsen-Bouterse S, Mohammad G, Kowluru RA, (2010) Glyceraldehyde-3-phosphate dehydrogenase in retinal microvasculature: implications for the development and progression of diabetic retinopathy, Invest. Ophthalmol. Vis. Sci 51: 1765-1772.
-
(2010)
Invest. Ophthalmol. Vis. Sci
, vol.51
, pp. 1765-1772
-
-
Madsen-Bouterse, S.1
Mohammad, G.2
Kowluru, R.A.3
-
33
-
-
0033551557
-
Over-expression of GAPDH induces apoptosis in COS-7 cells transfected with cloned GAPDH cDNAs
-
Tajima H, Tsuchiya K, Yamada M, Kondo K, Katsube N, et al. (1999) Over-expression of GAPDH induces apoptosis in COS-7 cells transfected with cloned GAPDH cDNAs. Neuroreport 10: 2029-2033.
-
(1999)
Neuroreport
, vol.10
, pp. 2029-2033
-
-
Tajima, H.1
Tsuchiya, K.2
Yamada, M.3
Kondo, K.4
Katsube, N.5
-
34
-
-
34247377425
-
GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization
-
Tarze A, Deniaud A, Le Bras M, Maillier E, Molle D, et al. (2007) GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization. Oncogene 26: 2606-2620.
-
(2007)
Oncogene
, vol.26
, pp. 2606-2620
-
-
Tarze, A.1
Deniaud, A.2
Le Bras, M.3
Maillier, E.4
Molle, D.5
-
35
-
-
84862668692
-
Phenylephrine protects cardiomyocytes from starvation-induced apoptosis by increasing glyceraldehyde-3-phosphate dehydrogenase (GAPDH) activity
-
Yao LL, Wang YG, Liu XJ, Zhou Y, Li N, et al. (2012) Phenylephrine protects cardiomyocytes from starvation-induced apoptosis by increasing glyceraldehyde-3-phosphate dehydrogenase (GAPDH) activity. J. Cell. Physiol 227: 3518-27.
-
(2012)
J. Cell. Physiol
, vol.227
, pp. 3518-3527
-
-
Yao, L.L.1
Wang, Y.G.2
Liu, X.J.3
Zhou, Y.4
Li, N.5
-
36
-
-
84865555754
-
Overexpression of glutaredoxin protects cardiomyocytes against nitric oxide-induced apoptosis with suppressing the S-nitrosylation of proteins and nuclear translocation of GAPDH
-
Inadomi C, Murata H, Ihara Y, Goto S, Urata Y, et al. (2012) Overexpression of glutaredoxin protects cardiomyocytes against nitric oxide-induced apoptosis with suppressing the S-nitrosylation of proteins and nuclear translocation of GAPDH, Biochem. Biophys. Res. Commun 425: 656-61.
-
(2012)
Biochem. Biophys. Res. Commun
, vol.425
, pp. 656-661
-
-
Inadomi, C.1
Murata, H.2
Ihara, Y.3
Goto, S.4
Urata, Y.5
-
37
-
-
0027518424
-
Sequence-specific binding of transfer RNA by glyceraldehyde-3-phosphate dehydrogenase
-
Singh R, Green MR, (1993) Sequence-specific binding of transfer RNA by glyceraldehyde-3-phosphate dehydrogenase. Science 259: 365-368.
-
(1993)
Science
, vol.259
, pp. 365-368
-
-
Singh, R.1
Green, M.R.2
-
38
-
-
1242294390
-
Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase
-
Sundararaj KP, Wood RE, Ponnusamy S, Salas AM, Szulc Z, et al. (2004) Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase. J. Biol. Chem 279: 6152-6162.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 6152-6162
-
-
Sundararaj, K.P.1
Wood, R.E.2
Ponnusamy, S.3
Salas, A.M.4
Szulc, Z.5
-
39
-
-
58149358873
-
Lats2 is a negative regulator of myocyte size in the heart
-
Matsui Y, Nakano N, Shao D, Gao S, Luo W, et al. (2008) Lats2 is a negative regulator of myocyte size in the heart. Circ. Res 103: 1309-1318.
-
(2008)
Circ. Res
, vol.103
, pp. 1309-1318
-
-
Matsui, Y.1
Nakano, N.2
Shao, D.3
Gao, S.4
Luo, W.5
-
40
-
-
77957825772
-
Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice
-
Del Re DP, Matsuda T, Zhai P, Gao S, Clark GJ, et al. (2010) Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice. J. Clin. Invest 120: 3555-3567.
-
(2010)
J. Clin. Invest
, vol.120
, pp. 3555-3567
-
-
Del Re, D.P.1
Matsuda, T.2
Zhai, P.3
Gao, S.4
Clark, G.J.5
|