Excitatory amino acid transporter 5 is widely expressed in peripheral tissues

European Journal of Histochemistry

Volumn 57, Issue 1, 2013, Pages 66-71

  Lee, A ^a   Anderson, A R ^a   Stevens, M G ^a   Beasley, S ^a   Barnett, N L ^a,b   Pow, D V ^c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b QUEENSLAND EYE INSTITUTE   (Australia)

^c RMIT UNIVERSITY   (Australia)

Author keywords

EAAT5; Glutamate; Heart; Kidney; Lung; Transporter

Indexed keywords

EID: 84875170954     PISSN: 1121760X     EISSN: None     Source Type: Journal    
DOI: 10.4081/ejh.2013.e11     Document Type: Article

References (28)

1. Danbolt NC. Glutamate uptake. Prog Neurobiol 2001;65:1-105.
2. Lee A, Pow DV. Astrocytes: glutamate transport and alternate splicing of transporters. Int J Biochem Cell Biol 2010;42:1901-1906.
3. Arriza JL, Eliasof S, Kavanaugh M P, Amara SG. Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proc Natl Acad Sci USA 1997;94:4155-4160.
4. Pow DV, Barnett NL. Developmental expression of excitatory amino acid transporter 5: a photoreceptor and bipolar cell glutamate transporter in rat retina. Neurosci Lett 2000;280:21-24.
5. Lee A, Anderson AR, Barnett NL, Stevens MG, Pow DV. Alternate splicing and expression of the glutamate transporter EAAT5 in the rat retina. Gene 2012;506:283-288.
6. Ochiai H, Saito M, Maruo T, Kanemaki N. Molecular cloning of canine excitatory amino acid transporter 5 and its detection in primary lens epithelial cells. Exp Anim 2010;59:449-457.
7. Lim R, Kindig AE, Lee A, Pow DV, Callister RJ, Brichta AM. EAAT5 mediates glutamate transport in mouse vestibular epithelium. Proceedings of the Australian Physiological Society, No. 40/83P. Australian Neuro - science, Sydney, NSW, 2010.
8. Dalet A, Bonsacquet J, Gaboyard-Niay S, Calin-Jageman I, Chidavaenzi RL, Venteo S, et al. Glutamate transporters EAAT4 and EAAT5 are expressed in vestibular hair cells calyx endings. PLoS One 2012;7: e46261.
9. Lee A, Anderson AR, Barnett AC, Chan A, Pow DV. Expression of multiple glutamate transporter splice variants in the rodent testis. Asian J Androl 2011;13:254-265.
10. Wersinger E, Schwab Y, Sahel JA, Rendon A, Pow DV, Picaud S, et al. The glutamate transporter EAAT5 works as a presynaptic receptor in mouse rod bipolar cells. J Physiol 2006;577(Pt 1):221-234.
11. Veruki ML, Mørkve SH, Hartveit E. Activation of a presynaptic glutamate transporter regulates synaptic transmission through electrical signaling. Nat Neurosci 2006;9:1388-1396.
12. Susarla BT, Seal R P, Zelenaia O, Watson DJ, Wolfe JH, Amara SG, et al. Differential regulation of GLAST immunoreactivity and activity by protein kinase C: evidence for modification of amino and carboxyl termini. J Neurochem 2004;91:1151-1163.
13. Williams SM, Sullivan RK, Scott HL, Finkelstein DI, Colditz PB, Lingwood BE, et al. Glial glutamate transporter expression patterns in brains from multiple mammalian species. Glia 2005;49:520-541.
14. Pow DV, Sullivan R, Scott H. Antibody production and immunocytochemical localization of amino acid transporters. Methods Mol Biol 2003;227:213-244.
15. Rauen T, Wiessner M, Sullivan R, Lee A, Pow DV. A new GLT1 splice variant: cloning and immunolocalization of GLT1c in the mammalian retina and brain. Neurochem Int 2004;45:1095-1106.
16. Pow DV. Immunocytochemistry of amino- acids in the rodent pituitary using extreme- ly specific, very high-titer antisera. J Neuroendocrinology 1993;5:349-356.
17. Fyk-Kolodziej B, Qin P, Dzhagaryan A, Pourcho RG. Differential cellular and sub- cellular distribution of glutamate transporters in the cat retina. Vis Neurosci 2004;21:551-565.
18. Song D, O'Regan MH, Phillis JW. Mechanisms of amino acid release from the isolated anoxic/reperfused rat heart. Eur J Pharmacol 1998;351:313-322.
19. Rennie MJ, Low SY, Taylor PM, Khogali SE, Yao PC, Ahmed A. Amino acid transport during muscle contraction and its relevance to exercise. Adv Exp Med Biol 1998;441:299-305.
20. Mourtzakis M, Graham TE. Glutamate ingestion and its effects at rest and during exercise in humans. J Appl Physiol 2002;93: 1251-1259.
21. Howell JA, Matthews AD, Swanson KC, Harmon DL, Matthews JC. Molecular identification of high-affinity glutamate transporters in sheep and cattle forestomach, intestine, liver, kidney, and pancreas. J Anim Sci 2001;79:1329-1336.
22. Shayakul C, Kanai Y, Lee WS, Brown D, Rothstein JD, Hediger MA. Localization of the high-affinity glutamate transporter EAAC1 in rat kidney. Am J Physiol 1997; 273:F1023-F1029.
23. Welbourne TC, Matthews JC. Glutamate transport and renal function. Am J Physiol 1999;277:F501-F505.
24. Valerius MT, McMahon A P. Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation. Gene Expr Patterns 2008;28:297-306.
25. Labow BI, Abcouwer SF, Lin CM, Souba WW. Glutamine synthetase expression in rat lung is regulated by protein stability. Am J Physiol 1998;275:L877-L886.
26. Pan M, Fischer CP, Wasa M, Bode BP, Souba WW. Characterization of glutamine and glutamate transport in rat lung plasma membrane vesicles. J Surg Res 1997;69:418-424.
27. Gill SS, Pulido OM. Glutamate receptors in peripheral tissues: current knowledge, future research, and implications for toxicology. Toxicol Pathol 2001;29:208-423.
28. Vallejo-Illarramendi A, Domercq M, Matute C. A novel alternative splicing form of excitatory amino acid transporter 1 is a negative regulator of glutamate uptake. J Neurochem 2005;95:341-348.