-
1
-
-
79953307244
-
Negative impact of bone metastasis on outcome in clear cell renal cell carcinoma treated with Sunitinib
-
Beuselinck B, Oudard S, Rixe O, Wolter P, Blesius A, Ayllon J, Elaidi R, Schoffski P, Barrascout E, Morel A, Escudier B, Lang H, Zucman-Rossi J, Medioni J (2011) Negative impact of bone metastasis on outcome in clear cell renal cell carcinoma treated with Sunitinib. Ann Oncol 22: 794-800.
-
(2011)
Ann Oncol
, vol.22
, pp. 794-800
-
-
Beuselinck, B.1
Oudard, S.2
Rixe, O.3
Wolter, P.4
Blesius, A.5
Ayllon, J.6
Elaidi, R.7
Schoffski, P.8
Barrascout, E.9
Morel, A.10
Escudier, B.11
Lang, H.12
Zucman-Rossi, J.13
Medioni, J.14
-
2
-
-
0344665555
-
ABC of oral bioavailability: Transporters as gatekeepers in the gut
-
Dietrich CG, Geier A, Oude Elferink RPJ (2003) ABC of oral bioavailability: transporters as gatekeepers in the gut. Gut 52: 1788-1795.
-
(2003)
Gut
, vol.52
, pp. 1788-1795
-
-
Dietrich, C.G.1
Geier, A.2
Oude Elferink, R.P.J.3
-
3
-
-
81255160848
-
Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with firstline sunitinib: A multicentre, observational, prospective study
-
Garcia-Donas J, Esteban E, Leandro-Garc?a LJ, Castellano DE, Del Alba AG, Climent MA, Arranz JA, Gallardo E, Puente J, Bellmunt J, Mellado B, Mart?nez E, Moreno F, Font A, Robledo M, Rodr?guez-Antona C (2011) Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with firstline sunitinib: a multicentre, observational, prospective study. Lancet Oncol 12: 1143-1150.
-
(2011)
Lancet Oncol
, vol.12
, pp. 1143-1150
-
-
Garcia-Donas, J.1
Esteban, E.2
Leandro-Garca, L.J.3
Castellano, D.E.4
Del Alba, A.G.5
Climent, M.A.6
Arranz, J.A.7
Gallardo, E.8
Puente, J.9
Bellmunt, J.10
Mellado, B.11
Martnez, E.12
Moreno, F.13
Font, A.14
Robledo, M.15
Rodrguez-Antona, C.16
-
4
-
-
58249094490
-
Metastatic sarcomatoid renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy
-
Golshayan AR, George S, Heng DY, Elson P, Wood LS, Mekhail TM, Garcia JA, Aydin H, Zhou M, Bukowski RM, Rini BI (2009) Metastatic sarcomatoid renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy. J Clin Oncol 27: 235-241.
-
(2009)
J Clin Oncol
, vol.27
, pp. 235-241
-
-
Golshayan, A.R.1
George, S.2
Heng, D.Y.3
Elson, P.4
Wood, L.S.5
Mekhail, T.M.6
Garcia, J.A.7
Aydin, H.8
Zhou, M.9
Bukowski, R.M.10
Rini, B.I.11
-
5
-
-
73349084973
-
Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: Results from a large, multicenter study
-
Heng DY, Xie W, Regan MM, Warren MA, Golshayan AR, Sahi C, Eigl BJ, Ruether JD, Cheng T, North S, Venner P, Knox JJ, Chi KN, Kollmannsberger C, McDermott DF, Oh WK, Atkins MB, Bukowski RM, Rini BI, Choueiri TK (2009) Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. J Clin Oncol 27: 5794-5799.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5794-5799
-
-
Heng, D.Y.1
Xie, W.2
Regan, M.M.3
Warren, M.A.4
Golshayan, A.R.5
Sahi, C.6
Eigl, B.J.7
Ruether, J.D.8
Cheng, T.9
North, S.10
Venner, P.11
Knox, J.J.12
Chi, K.N.13
Kollmannsberger, C.14
McDermott, D.F.15
Oh, W.K.16
Atkins, M.B.17
Bukowski, R.M.18
Rini, B.I.19
Choueiri, T.K.20
more..
-
6
-
-
77953033291
-
Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: Results of a pharmacokinetic/pharmacodynamic meta-analysis
-
Houk BE, Bello CL, Poland B, Rosen LS, Demetri GD, Motzer RJ (2010) Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis. Cancer Chemother Pharmacol 66: 357-371.
-
(2010)
Cancer Chemother Pharmacol
, vol.66
, pp. 357-371
-
-
Houk, B.E.1
Bello, C.L.2
Poland, B.3
Rosen, L.S.4
Demetri, G.D.5
Motzer, R.J.6
-
7
-
-
45149099137
-
Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer
-
Meyer KB, Maia AT, O'Reilly M, Teschendorff AE, Chin SF, Caldas C, Ponder BA (2008) Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer. PLoS Biol 5: e108.
-
(2008)
PLoS Biol
, vol.5
-
-
Meyer, K.B.1
Maia, A.T.2
O'Reilly, M.3
Teschendorff, A.E.4
Chin, S.F.5
Caldas, C.6
Ponder, B.A.7
-
8
-
-
4644354183
-
Prognostic factors for survival of patients with stage IV renal cell carcinoma: Memorial Sloan Kettering Cancer Center experience
-
Motzer R, Bacik J, Mazumbar M (2004) Prognostic factors for survival of patients with stage IV renal cell carcinoma: Memorial Sloan Kettering Cancer Center experience. Clin Cancer Res 10: 6202S-6203S.
-
(2004)
Clin Cancer Res
, vol.10
-
-
Motzer, R.1
Bacik, J.2
Mazumbar, M.3
-
9
-
-
68949145218
-
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Oudard S, Negrier S, Szczylik C, Pili R, Bjarnason GA, Garcia-del-Muro X, Sosman JA, Solska E, Wilding G, Thompson JA, Kim ST, Chen I, Huang X, Figlin RA (2009) Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol 27: 3584-3590.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3584-3590
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Oudard, S.6
Negrier, S.7
Szczylik, C.8
Pili, R.9
Bjarnason, G.A.10
Garcia-Del-Muro, X.11
Sosman, J.A.12
Solska, E.13
Wilding, G.14
Thompson, J.A.15
Kim, S.T.16
Chen, I.17
Huang, X.18
Figlin, R.A.19
-
10
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, Oudard S, Negrier S, Szczylik C, Kim ST, Chen I, Bycott PW, Baum CM, Figlin RA (2007) Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 356: 115-124.
-
(2007)
N Engl J Med
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
11
-
-
0033451902
-
Lack of lymphatic vascular specificity of vascular endothelial growth factor 3 in 185 vascular tumors
-
Partanen TA, Alitalo K, Miettinen M (1999) Lack of lymphatic vascular specificity of vascular endothelial growth factor 3 in 185 vascular tumors. Cancer 86: 2406-2412.
-
(1999)
Cancer
, vol.86
, pp. 2406-2412
-
-
Partanen, T.A.1
Alitalo, K.2
Miettinen, M.3
-
12
-
-
79251574372
-
Prognostic factors for progression free survival and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinoma
-
Patil S, Figlin R, Hutson T, Michaelson M, Negrier S, Kim T, Huang X, Motzer R (2011) Prognostic factors for progression free survival and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinoma. Ann Oncol 22: 295-300.
-
(2011)
Ann Oncol
, vol.22
, pp. 295-300
-
-
Patil, S.1
Figlin, R.2
Hutson, T.3
Michaelson, M.4
Negrier, S.5
Kim, T.6
Huang, X.7
Motzer, R.8
-
13
-
-
84862908315
-
Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing
-
Reumers J, De Rijk P, Zhao H, Liekens A, Smeets D, Cleary J, Van Loo P, Van Den Bossche M, Catthoor K, Sabbe B, Despierre E, Vergote I, Hilbush B, Lambrechts D, Del-Favero J (2011) Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing. Nat Biotechnol 30: 61-68.
-
(2011)
Nat Biotechnol
, vol.30
, pp. 61-68
-
-
Reumers, J.1
De Rijk, P.2
Zhao, H.3
Liekens, A.4
Smeets, D.5
Cleary, J.6
Van Loo, P.7
Van Den Bossche, M.8
Catthoor, K.9
Sabbe, B.10
Despierre, E.11
Vergote, I.12
Hilbush, B.13
Lambrechts, D.14
Del-Favero, J.15
-
14
-
-
70349385645
-
Resistance to targeted therapy in renal-cell carcinoma
-
Rini BI, Atkins MB (2009) Resistance to targeted therapy in renal-cell carcinoma. Lancet Oncol 10: 992-1000.
-
(2009)
Lancet Oncol
, vol.10
, pp. 992-1000
-
-
Rini, B.I.1
Atkins, M.B.2
-
15
-
-
67649336584
-
P-glycoprotein activity in renal clear cell carcinoma
-
Soto-Vega E, Arroyo C, Richaud-Patin Y, Garcia-Carrasco M, Vazquez-Lavista LG, Llorente L (2009) P-glycoprotein activity in renal clear cell carcinoma. Urol Oncol 27: 363-366.
-
(2009)
Urol Oncol
, vol.27
, pp. 363-366
-
-
Soto-Vega, E.1
Arroyo, C.2
Richaud-Patin, Y.3
Garcia-Carrasco, M.4
Vazquez-Lavista, L.G.5
Llorente, L.6
-
16
-
-
0032933883
-
VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
-
Valtola R, Salven P, Heikkil P, Taipale J, Joensuu H, Rehn M, Pihlajaniemi T, Weich H, deWaal R, Alitalo K (1999) VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer. Am J Pathol 154: 1381-1390.
-
(1999)
Am J Pathol
, vol.154
, pp. 1381-1390
-
-
Valtola, R.1
Salven, P.2
Heikkil, P.3
Taipale, J.4
Joensuu, H.5
Rehn, M.6
Pihlajaniemi, T.7
Weich, H.8
Dewaal, R.9
Alitalo, K.10
-
17
-
-
79551701442
-
Genetic polymorphisms associated with a prolonged progressionfree survival in patients with metastatic renal cell cancer treated with sunitinib
-
van der Veldt AA, Eechoute K, Gelderblom H, Gietema J, Guchelaar HJ, van Erp NP, van den Eertwegh AJ, Haanen JB, Mathijssen RH, Wessels JA (2010) Genetic polymorphisms associated with a prolonged progressionfree survival in patients with metastatic renal cell cancer treated with sunitinib. Clin Cancer Res 17: 620-629.
-
(2010)
Clin Cancer Res
, vol.17
, pp. 620-629
-
-
Van Der Veldt, A.A.1
Eechoute, K.2
Gelderblom, H.3
Gietema, J.4
Guchelaar, H.J.5
Van Erp, N.P.6
Van Den Eertwegh, A.J.7
Haanen, J.B.8
Mathijssen, R.H.9
Wessels, J.A.10
-
18
-
-
68849086857
-
Expression of multidrug resistance markers ABCB1 (MDR-1/P-gp) and ABCC1 (MRP-1) in renal cell carcinoma
-
Walsh N, Larkin A, Kennedy S, Connolly L, Ballot J, Ooi W, Gullo G, Crown J, Clynes M, O'Driscoll L (2009) Expression of multidrug resistance markers ABCB1 (MDR-1/P-gp) and ABCC1 (MRP-1) in renal cell carcinoma. BMC Urol 9: 6.
-
(2009)
BMC Urol
, vol.9
, pp. 6
-
-
Walsh, N.1
Larkin, A.2
Kennedy, S.3
Connolly, L.4
Ballot, J.5
Ooi, W.6
Gullo, G.7
Crown, J.8
Clynes, M.9
O'Driscoll, L.10
-
19
-
-
79959316184
-
Pazopanib efficacy in renal cell carcinoma: Evidence for predictive genetic markers in angiogenesisrelated and exposure-related genes
-
Xu CF, Bing NX, Ball HA, Rajagopalan D, Sternberg CN, Hutson TE, de Souza P, Xue ZG, McCann L, King KS, Ragone LJ, Whittaker JC, Spraggs CF, Cardon LR, Mooser VE, Pandite LN (2011a) Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesisrelated and exposure-related genes. J Clin Oncol 29: 2557-2564.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2557-2564
-
-
Xu, C.F.1
Bing, N.X.2
Ball, H.A.3
Rajagopalan, D.4
Sternberg, C.N.5
Hutson, T.E.6
De Souza, P.7
Xue, Z.G.8
McCann, L.9
King, K.S.10
Ragone, L.J.11
Whittaker, J.C.12
Spraggs, C.F.13
Cardon, L.R.14
Mooser, V.E.15
Pandite, L.N.16
-
20
-
-
79960364924
-
Association of genetic markers in angiogenesisor exposure-related genes with overall survival in pazopanib-treated patients with advanced renal cell carcinoma
-
abstr 303
-
Xu CF, Ball HA, Bing N, Sternberg C, Xue Z, McCann L, King K, Spraggs C, Mooser V, Pandite LN (2011b) Association of genetic markers in angiogenesisor exposure-related genes with overall survival in pazopanib-treated patients with advanced renal cell carcinoma. J Clin Oncol 29(Suppl 7): abstr 303.
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL. 7
-
-
Xu, C.F.1
Ball, H.A.2
Bing, N.3
Sternberg, C.4
Xue, Z.5
McCann, L.6
King, K.7
Spraggs, C.8
Mooser, V.9
Pandite, L.N.10
|