Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets

American Journal of Pathology

Volumn 182, Issue 4, 2013, Pages 1347-1356

  Van Oosterwijk, Jolieke G ^a   Meijer, Danielle ^a   Van Ruler, Maayke A J H ^a   Van Den Akker, Brendy E W M ^a   Oosting, Jan ^a   Krenács, Tibor ^b   Picci, Piero ^c   Flanagan, Adrienne M ^d   Liegl Atzwanger, Bernadette ^e   Leithner, Andreas ^e   Athanasou, Nick ^f   Daugaard, Søren ^g   Hogendoorn, Pancras C W ^a   Bovée, Judith V M G ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e MEDICAL UNIVERSITY OF GRAZ   (Austria)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g Mental Health Center Glostrup   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; CISPLATIN; DOXORUBICIN; FIBROBLAST GROWTH FACTOR RECEPTOR 3; PROTEIN BCL 2; PROTEIN BCL XL; PROTEOHEPARAN SULFATE; SMAD2 PROTEIN; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA;

ADULT; AGED; ARTICLE; CELLULAR DISTRIBUTION; CHONDROSARCOMA; CLEAR CELL CHONDROSARCOMA; CONTROLLED STUDY; DEDIFFERENTIATED CHONDROSARCOMA; DRUG SENSITIVITY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; TISSUE MICROARRAY;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; CELL DEDIFFERENTIATION; CHONDROSARCOMA, MESENCHYMAL; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MOLECULAR TARGETED THERAPY; NEOPLASM PROTEINS; PARAFFIN EMBEDDING; PROTO-ONCOGENE PROTEINS C-BCL-2; SARCOMA, CLEAR CELL; SIGNAL TRANSDUCTION; TISSUE FIXATION; TRANSFORMING GROWTH FACTOR BETA; YOUNG ADULT;

EID: 84875163071     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.12.036     Document Type: Article

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