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Volumn 2, Issue 1, 2013, Pages 77-91

SGLT inhibitors: A novel target for diabetes

Author keywords

[No Author keywords available]

Indexed keywords

3 (5 BENZOFURANYL) 1 [2 HYDROXY 6 [6 O (METHOXYCARBONYL) BETA DEXTRO GLUCOPYRANOSYL] 4 METHYLPHENYL] 1 PROPANONE; ANTIDIABETIC AGENT; BI 44847; CAFFEINE; CANAGLIFLOZIN; CSG 4524; DAPAGLIFLOZIN; EGT 0001442; EMPAGLIFLOZIN; EPIGALLOCATECHIN GALLATE; ERTUGLIFLOZIN; GLUCOSE; IPRAGLIFLOZIN; KGA 3235; KGT 1075; KGT 1611; LX 4211; METFORMIN; NSC 2833; PHLORIZIN; PLACEBO; PROTEIN INHIBITOR; REMOGLIFLOZIN; SERGLIFLOZIN ETABONATE; SITAGLIPTIN; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 2; SODIUM GLUCOSE COTRANSPORTER INHIBITOR; TOFOGLIFLOZIN; TS 071; UNCLASSIFIED DRUG; UNINDEXED DRUG; YM 543;

EID: 84875157685     PISSN: 20468954     EISSN: 20468962     Source Type: Journal    
DOI: 10.4155/ppa.12.78     Document Type: Review
Times cited : (20)

References (26)
  • 1
    • 82955247909 scopus 로고    scopus 로고
    • IDF diabetes atlas: Global estimates of the prevalence of diabetes for 2011 and 2030
    • Whiting DR, Guariguata L, Weil C, Shaw J. IDF diabetes atlas: Global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes Res. Clin. Pract. 94(3), 311-321 (2011).
    • (2011) Diabetes Res. Clin. Pract , vol.94 , Issue.3 , pp. 311-321
    • Whiting, D.R.1    Guariguata, L.2    Weil, C.3    Shaw, J.4
  • 2
    • 0034997336 scopus 로고    scopus 로고
    • Renal Na-glucose cotransporters
    • Wright EM. Renal Na-glucose cotransporters. Am. J. Renal Physiol. 280, F10-F18 (2001).
    • (2001) Am. J. Renal Physiol , vol.280
    • Wright, E.M.1
  • 3
    • 80054108953 scopus 로고    scopus 로고
    • Sodium-glucose cotransporter 2 inhibitors in the treatment of type 2 diabetes: A review of Phase II and III trials
    • Kipnes MS. Sodium-glucose cotransporter 2 inhibitors in the treatment of type 2 diabetes: A review of Phase II and III trials. Clin. Invest. 1(1), 145-156 (2011).
    • (2011) Clin. Invest , vol.1 , Issue.1 , pp. 145-156
    • Kipnes, M.S.1
  • 4
    • 84858212683 scopus 로고    scopus 로고
    • Sodium glucose co transporter 2 (SGLT2) inhibitors: A new sword for the treatment of type 2 diabetes mellitus
    • Rajesh R, Naren P, vidyasagar S. Sodium glucose co transporter 2 (SGLT2) inhibitors: A new sword for the treatment of type 2 diabetes mellitus. Int. J. Pharm. Sci. 1(2), 139-147 (2010).
    • (2010) Int. J. Pharm. Sci , vol.1 , Issue.2 , pp. 139-147
    • Rajesh, R.1    Naren, P.2    Vidyasagar, S.3
  • 5
    • 77949287535 scopus 로고    scopus 로고
    • Sodium-glucose co-transport inhibitors progress and therapeutic potential in type 2 diabetes mellitus
    • Neumiller JJ, WhiteJr JR, Campbell RK. Sodium-glucose co-transport inhibitors progress and therapeutic potential in type 2 diabetes mellitus. Drugs70 (4), 377-385 (2010).
    • (2010) Drugs70 , vol.4 , pp. 377-385
    • Neumiller, J.J.1    Whitejr, J.R.2    Campbell, R.K.3
  • 6
    • 0028239439 scopus 로고
    • A functional superfamily of sodium/solute symporters
    • Reizer J, Reizer A, Saier MH Jr. A functional superfamily of sodium/solute symporters. BBA-Biomembranes 1197, 133-166 (1994).
    • (1994) BBA-Biomembranes , vol.1197 , pp. 133-166
    • Reizer, J.1    Reizer, A.2    Saier Jr., M.H.3
  • 7
    • 0034118154 scopus 로고    scopus 로고
    • Glucose transporters: Structure, function, and consequences of deficiency
    • Brown GK. Glucose transporters: Structure, function, and consequences of deficiency. J. Inherited Metab. Dis. 23, 237-246 (2000).
    • (2000) J. Inherited Metab. Dis , vol.23 , pp. 237-246
    • Brown, G.K.1
  • 8
    • 1242272759 scopus 로고    scopus 로고
    • The sodium/glucose cotransport family SLC5
    • Wright EM, Turk, E. The sodium/glucose cotransport family SLC5. Pflugers Arch. 447, 510-518 (2004).
    • (2004) Pflugers Arch , vol.447 , pp. 510-518
    • Wright, E.M.1    Turk, E.2
  • 9
    • 0035879385 scopus 로고    scopus 로고
    • Changes in sodium or glucose filtration rate modulate expression of glucose transporters in renal proximal tubular cells of rat
    • Vestri S, Okamoto MM, de Freitas HS et al Changes in sodium or glucose filtration rate modulate expression of glucose transporters in renal proximal tubular cells of rat. J. Membr. Biol. 182, 105-112 (2001).
    • (2001) J. Membr. Biol , vol.182 , pp. 105-112
    • Vestri, S.1    Okamoto, M.M.2    De Freitas, H.S.3
  • 10
    • 57949111356 scopus 로고    scopus 로고
    • Petering DH Enhanced expressions of sodium-glucose cotransporters in the kidneys of diabetic zucker rats enhanced expressions of sodium-glucose cotransporters in the kidneys of diabetic zucker rats
    • Tabatabai NM, Sharma M, Blumenthal SS et al. Petering DH. Enhanced expressions of sodium-glucose cotransporters in the kidneys of diabetic zucker rats enhanced expressions of sodium-glucose cotransporters in the kidneys of diabetic zucker rats. Diabetes Res. Clin. Pract. 83(1), e27-e30 (2009).
    • (2009) Diabetes Res. Clin. Pract , vol.83 , Issue.1
    • Tabatabai, N.M.1    Sharma, M.2    Blumenthal, S.S.3
  • 11
    • 33644688031 scopus 로고    scopus 로고
    • Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
    • Rahmoune H, Thompson PW, Ward JM et al. Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes. Diabetes 54, 3427-3434 (2005).
    • (2005) Diabetes , vol.54 , pp. 3427-3434
    • Rahmoune, H.1    Thompson, P.W.2    Ward, J.M.3
  • 13
    • 77954242599 scopus 로고    scopus 로고
    • SGLT2 inhibition - A novel strategy for diabetes treatment
    • Chao EC, RR Henry. SGLT2 inhibition - a novel strategy for diabetes treatment. Nature Rev. Drug Discov. 9 (7), 551-559 (2010).
    • (2010) Nature Rev. Drug Discov , vol.9 , Issue.7 , pp. 551-559
    • Chao, E.C.1    Henry, R.R.2
  • 14
    • 0032850016 scopus 로고    scopus 로고
    • T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes
    • Oku A, K Ueta, K Arakawa et al. T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes. Diabetes 48, 1794-1800 (1999).
    • (1999) Diabetes , vol.48 , pp. 1794-1800
    • Oku, A.1    Ueta, K.2    Arakawa, K.3
  • 15
    • 41649087328 scopus 로고    scopus 로고
    • Discovery of dapagliflozin: A potent, selective renal sodium-dependent glucose cotransporter2 (SGLT2) inhibitor for the treatment of type 2 diabetes
    • Meng W, Ellsworth BA, Nirschl AA et al. Discovery of dapagliflozin: A potent, selective renal sodium-dependent glucose cotransporter2 (SGLT2) inhibitor for the treatment of type 2 diabetes. J. Med. Chem. 51, 1145-1149 (2008).
    • (2008) J. Med. Chem , vol.51 , pp. 1145-1149
    • Meng, W.1    Ellsworth, B.A.2    Nirschl, A.A.3
  • 16
    • 48249146624 scopus 로고    scopus 로고
    • Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats
    • Han S, Hagan DL, Taylor JR et al. Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats. Diabetes 57, 1723-1729 (2008).
    • (2008) Diabetes , vol.57 , pp. 1723-1729
    • Han, S.1    Hagan, D.L.2    Taylor, J.R.3
  • 17
    • 77957128949 scopus 로고    scopus 로고
    • SGLT2 inhibitors: Glucuretic treatment for type 2 diabetes
    • Bailey CJ, Day C. SGLT2 inhibitors: Glucuretic treatment for type 2 diabetes. Br. J. Diab. Vasc. Dis. 10, 193-199 (2010).
    • (2010) Br. J. Diab. Vasc. Dis , vol.10 , pp. 193-199
    • Bailey, C.J.1    Day, C.2
  • 18
    • 84860252876 scopus 로고    scopus 로고
    • Canagliflozin improves glycaemic control over 28 days in subjects with type 2 diabetes not optimally controlled on insulin
    • Devineni D, Morrow L, Hompesch M. Canagliflozin improves glycaemic control over 28 days in subjects with type 2 diabetes not optimally controlled on insulin. Diabetes Obes. Metab. 14, 539-545 (2012).
    • (2012) Diabetes Obes. Metab. , vol.14 , pp. 539-545
    • Devineni, D.1    Morrow, L.2    Hompesch, M.3
  • 19
    • 34249853401 scopus 로고    scopus 로고
    • Review of sitagliptin phosphate: A novel treatment for type 2 diabetes
    • Gallwitz B. Review of sitagliptin phosphate: A novel treatment for type 2 diabetes. Vasc. Health Risk Manag. 3(2), 203-210 (2007).
    • (2007) Vasc. Health Risk Manag , vol.3 , Issue.2 , pp. 203-210
    • Gallwitz, B.1
  • 20
    • 67349275999 scopus 로고    scopus 로고
    • Dapagliflozin, a novel,selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus
    • Komoroski B, Vachharajani N, Feng Y et al. Dapagliflozin, a novel,selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus. Clin. Pharmacol. Ther. 85, 513-519 (2009).
    • (2009) Clin. Pharmacol. Ther , vol.85 , pp. 513-519
    • Komoroski, B.1    Vachharajani, N.2    Feng, Y.3
  • 21
    • 65349196064 scopus 로고    scopus 로고
    • Sodium- glucose cotransport inhibition with dapagliflozin in type 2 diabetes
    • List JF, Woo V, Morales E et al. Sodium- glucose cotransport inhibition with dapagliflozin in type 2 diabetes. Diabetes Care 32, 650-657 (2009).
    • (2009) Diabetes Care , vol.32 , pp. 650-657
    • List, J.F.1    Woo, V.2    Morales, E.3
  • 22
    • 69549095914 scopus 로고    scopus 로고
    • T'joen C et a.l.
    • Wilding JP, Norwood P, T'joen C et al. A study of dapagliflozin in patients with type 2 diabetes receiving high doses of insulin plus insulin sensitizers: Applicability of a novel insulin-independent treatment. Diabetes Care 32, 1656-1662 (2009).
    • (2009) Diabetes Care , vol.32 , pp. 1656-1662
    • Wilding, J.P.1    Norwood, P.2
  • 23
    • 67349189212 scopus 로고    scopus 로고
    • Renal sodium-glucose transport: Role in diabetes and potential clinical implications
    • Bakris GL, Fonseca VA, Sharma K et al. Renal sodium-glucose transport: Role in diabetes and potential clinical implications. Kidney Int. 75, 1272-1277 (2009).
    • (2009) Kidney Int , vol.75 , pp. 1272-1277
    • Bakris, G.L.1    Fonseca, V.A.2    Sharma, K.3
  • 24
    • 0141640818 scopus 로고    scopus 로고
    • Human cardiomyocytes express high levels of Na+/glucose cotransporter 1 (SGLT1)
    • Zhou L, Cryan EV, D'Andrea MR et al. Human cardiomyocytes express high levels of Na+/glucose cotransporter 1 (SGLT1). J. Cell Biochem. 90, 339-346 (2003).
    • (2003) J. Cell Biochem , vol.90 , pp. 339-346
    • Zhou, L.1    Cryan, E.V.2    D'Andrea, M.R.3
  • 25
    • 70449729537 scopus 로고    scopus 로고
    • SGLT1 Is A Novel Cardiac Glucose Transporter That Is Perturbed In Disease States Cardiovasc
    • Banerjee SK, McGaffin KR, Pastor-Soler NM, F. et al. SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states, Cardiovasc. Res. 84, 111-118 (2009).
    • (2009) Res , vol.84 , pp. 111-118
    • Banerjee, S.K.1    McGaffin, K.R.2    Pastor-Soler, N.M.F.3
  • 26
    • 77956175828 scopus 로고    scopus 로고
    • SGLT1, a novel cardiac glucose transporter, mediates increased glucose uptake in PRKAG2 cardiomyopathy
    • Banerjee SK, Wang DW, Alzamora R, Huang XN et al. SGLT1, a novel cardiac glucose transporter, mediates increased glucose uptake in PRKAG2 cardiomyopathy. J. Mol. Cell. Cardiol. 49, 683-692 (2010).
    • (2010) J. Mol. Cell. Cardiol , vol.49 , pp. 683-692
    • Banerjee, S.K.1    Wang, D.W.2    Alzamora, R.3    Huang, X.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.