Selective mGAT2 (BGT-1) GABA uptake inhibitors: Design, synthesis, and pharmacological characterization

Journal of Medicinal Chemistry

Volumn 56, Issue 5, 2013, Pages 2160-2164

  Vogensen, Stine B ^a   Jørgensen, Lars ^a   Madsen, Karsten K ^a   Borkar, Nrupa ^a   Wellendorph, Petrine ^a   Skovgaard Petersen, Jonas ^a   Schousboe, Arne ^a   White, H Steve ^b   Krogsgaard Larsen, Povl ^a   Clausen, Rasmus P ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID UPTAKE INHIBITOR; [4,4 BIS(3 METHYLTHIEN 2 YL)BUT 3 ENYL](2 CARBOXYCYCLOHEX 2 ENYL)METHYLAMMONIUM CHLORIDE; ANTICONVULSIVE AGENT; TIAGABINE; UNCLASSIFIED DRUG;

ANTICONVULSANT ACTIVITY; ARTICLE; CENTRAL NERVOUS SYSTEM; DRUG DESIGN; DRUG EFFECT; DRUG SYNTHESIS; EPILEPSY; MOUSE; NONHUMAN;

ANIMALS; CELLS, CULTURED; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GABA UPTAKE INHIBITORS; INHIBITORY CONCENTRATION 50; ISOXAZOLES; MICE; NEURONS;

EID: 84875137124     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301872x     Document Type: Article

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