Development and characterization of a cocrystal as a viable solid form for an active pharmaceutical ingredient

Organic Process Research and Development

Volumn 17, Issue 3, 2013, Pages 540-548

  Kim, Soojin ^a   Li, Zhibin ^a   Tseng, Yin Chao ^a   Nar, Herbert ^b   Spinelli, Earl ^a   Varsolona, Richard ^a,c   Reeves, Jonathan T ^a   Lee, Heewon ^a   Song, Jinhua J ^a   Smoliga, John ^a   Yee, Nathan ^a   Senanayake, Chris ^a  

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; BOEHRINGER INGELHEIM; COCRYSTAL STRUCTURE; CRYSTALLIZATION SYSTEMS; EFFECTIVE PARTICLE SIZE; HYDROGEN BONDING INTERACTIONS; PHYSICOCHEMICAL PROPERTY; SINGLE CRYSTAL X-RAY STRUCTURES;

BIOCHEMISTRY; CRYSTAL STRUCTURE; CRYSTALLIZATION KINETICS; HYDROGEN BONDS; PHOSPHORIC ACID;

MOLECULES;

EID: 84875130897     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op300239h     Document Type: Article

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