Impact of gold nanoparticle concentration on their cellular uptake by MC3T3-E1 mouse osteoblastic cells as analyzed by transmission electron microscopy

Journal of Nanomedicine and Nanotechnology

Volumn 2, Issue 6, 2011, Pages

  Mustafa, Thikra ^a   Watanabe, Fumiya ^a   Monroe, William ^b   Mahmood, Meena ^a   Xu, Yang ^a   Saeed, Lamya Mohammed ^a   Karmakar, Alokita ^a   Casciano, Dan ^a   Ali, Syed ^c   Biris, Alexandru S ^a  

^a UNIVERSITY OF ARKANSAS AT LITTLE ROCK   (United States)

^b MISSISSIPPI STATE UNIVERSITY   (United States)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Gold nanoparticles; MC3T3 E1 mouse osteoblastic cells; Transmission electron microscopy; Uptake mechanism

Indexed keywords

EID: 84875097429     PISSN: None     EISSN: 21577439     Source Type: Journal    
DOI: 10.4172/2157-7439.1000118     Document Type: Article

References (36)

1. Harjanto D (2006) Gold nanoparticle-assisted delivery of TNF-α in thermal treatments of cancer. Nnin Reu Research Accomplishments: 8-9.
2. Kang B, Mackey M, El-Sayed M (2010) Nuclear targeting of gold nanoparticles in cancer cells induces DNA damage, causing cytokinesis arrest and apoptosis. J Am Chem Soc 132: 1517-1519.
3. Kirui D, Rey D, Batt C (2010) Gold hybrid nanoparticles for targeted phototherapy and cancer imaging. Nanotechnology 21: 1-10.
4. Singh R, Pantarotto D, McCarthy D, Chaloin O, Hoebeke J, et al. (2005) Binding and condensation of plasmid DNA onto functionalized carbon nanotubes: Toward the construction of nanotube-based gene delivery vectors. J Am Chem Soc 127: 4388-4396.
5. Ladeira M, Andrade V, Gomes E, Aguiar C, Moraes E, et al. (2010) Highly efficient siRNA delivery system into human and murine cells using single-wall carbon nanotubes. Nanotechnology 21: 385101-385112.
6. Karmakar A, Bratton S, Dervishi E, Ghosh A, Mahmood M, et al. (2011) Ethylenediamine functionalized-single walled nanotube (f-SWNT)-assisted in vitro delivery of oncogene suppressor p53 gene to breast cancer MCF-7 cells. Int J Nanomedicine 6: 1045-1055.
7. Chithrani B, Ghazani A, Chan W (2006) Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Letters 6: 662-668.
8. Osaki F, Kanamori T, Sando S, Sera T, Aoyama Y (2004) A quantum dot conjugated sugar ball and its cellular uptake on the size effects of endocytosis in the subviral region. J Am Chem Soc 126: 6520-6521.
9. Thorek D, Chen A, Czupryna J, Tsourkas A (2006) Superparamagnetic iron oxide nanoparticle probes for molecular imaging. Ann Biomed Eng 34: 23-38.
10. Peng XH, Qian X, Mao H, Wang AY, Chen ZG, et al. (2008) Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy. Int J Nanomedicine 3: 311-321.
11. Mahmood M, Xu Y, Li Z, Dervishi E., Ali N, et al. (2009) Graphitic materials for RF thermal ablation of tumors. IEEE 45: 2162-2169.
12. Yang L, Mao H, Wang Y, Cao Z, Peng X, et al. (2009) Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging. Small 5: 235-243.
13. Lee KD, Nir S, Papahadjopoulos D (1993) Quantitative analysis of liposome-cell interactions in vitro: Rate constants of binding and endocytosis with suspension and adherent J774 cells and human monocytes. Biochemistry 32: 889-899.
14. Zhang Y, Yang M, Portney N, Cui D, Budak G, et al. (2008) Zeta potential: A surface electrical characteristic to probe the interaction of nanoparticles with normal and cancer human breast epithelial cells. Biomedical Microdevices 10: 321-328.
15. Chenevier P, Veyret B, Roux D, Henry-Toulme N (2000) Interaction of cationic colloids at the surface of J774 cells: A kinetic analysis. Biophysical Journal 79: 1298-1309.
16. Zhang Y, Xu Y, Li Z, Chen T, Lantz S, et al. (2011) Mechanistic toxicity evaluation of pristine and PEGylated single-walled carbon nanotubes in neuronal PC12 cells. ACS Nano 5: 7020-7033.
17. Mukherjee P, Bhattacharya R, Wang P, Wang L, Basu S, et al. (2005) Antiangiogenic properties of gold nanoparticles. Clinical Cancer Research 11: 3530-3534.
18. DanDan L, Jinchao Z, ChangQing Y, Mengsu Y (2010) The effects of gold nanoparticles on the proliferation, differentiation, and mineralization function of MC3T3-E1 cells in vitro. Chinese Science Bulletin 55: 1013-1019.
19. Zhang Z, Ross RD, Roeder RK (2010) Preparation of functionalized gold nanoparticles as a targeted X-ray contrast agent for damaged bone tissue. Nanoscale 2: 582-586.
20. Connor E, Mwamuka J, Gole A, Murphy C, Wyatt M (2005) Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 1: 325-327.
21. Frens G (1973) Controlled nucleation for the regulation of the particle size in monodisperse gold suspensions. Nature Physical Science 241: 20-22.
22. De Jong WH, Hagens WI, Krystek P, Burger MC, Sips AJ, et al. (2008) Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials 29: 1912-1919.
23. Gupta AK, Curtis AS (2004) Surface modified superparamagnetic nanoparticles for drug delivery: Interaction studies with human fibroblasts in culture. J Mater Sci Mater Med 15: 493-496.
24. Jiang W, Kim BY, Rutka JT, Chan WC (2008) Nanoparticle-mediated cellular response is size-dependent. Nat Nanotechnology 3: 145-150.
25. Chithrani BD, Chan WC (2007) Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. Nano Lett 7: 1542-1550.
26. Mahmood M, Li Z, Casciano D, Khodakovskaya MV, Chen T et al. (2010) Nanostructural materials increase mineralization in bone cells and affect gene expression through miRNA regulation. J Cell Mol Med 15: 2297-2306.
27. Turkevich J, Stevenson P, Hillier J (1951) A study of the nucleation and growth processes in the synthesis of colloidal gold. Discuss Faraday Soc 11: 55-75.
28. Patra Hk, Banerjee S, Chaudhuri U, Lahiri P, Dasgupta AK (2007) Cell selective response to gold nanoparticles. Nanomedicine 3: 111-119.
29. Pan Y, Neuss S, Leifert A, Fischler M, Wen F et al. (2007) Size-dependent cytotoxicity of gold nanoparticles. Small: 1941-1949.
30. Liu Y, Meyer-Zaika W, Franzka S, Schmid G, Tsoli M, et al. (2003) Goldcluster degradation by the transition of B-DNA into A-DNA and the formation of nanowires. Angewandte Chemie 42: 2853- 2857.
31. Geiser M, Rothen-Rutishauser B, Kapp N, Schürch S, Kreyling W, et al. (2005) Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells. Environ Health Perspect 113: 1555-1560.
32. Rothen-Rutishauser BM, Schürch S, Haenni B, Kapp N, Gehr P (2006) Interaction of fine particles and nanoparticles with red blood cells visualized with advanced microscopic techniques. Environ Sci Technol 40: 4353-4359.
33. Burke J (1970) Cell Biology. Williams and Wilkins Company, Baltimore:132-134.
34. Stearns RC, Paulauskis JD, Godleski JJ (2001) Endocytosis of ultrafine particles by A549 cells. Am J Respir Cell Mol Biol 24: 108-115.
35. Absolom DR, Zingg W, Neumann A (1987) Protein adsorption to polymer particles: Role of surface properties. J Biomed Mater Res 21: 161-171.
36. Cedervall T, Lynch I, Foy M, Berggard T, Donnelly S, et al. (2007) Detailed identification of plasma proteins adsorbed on copolymer nanoparticles. Angewandte Chemie 46: 5754-5756.