Functional role of vasoactive intestinal polypeptide in inhibitory motor innervation in the mouse internal anal sphincter

Journal of Physiology

Volumn 591, Issue 6, 2013, Pages 1489-1506

  Keef, K D ^a   Saxton, S N ^a   Mcdowall, R A ^a   Kaminski, R E ^a   Duffy, A M ^a   Cobine, C A ^a  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (2 IODO 6 METHYLAMINO 9H PURIN 9 YL) 2 PHOSPHONOOXYBICYCLO[3.1.0]HEXANE 1 METHANOL; N(G) NITROARGININE; NEURONAL NITRIC OXIDE SYNTHASE; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL TISSUE; ANUS SPHINCTER; ARTICLE; CONTROLLED STUDY; ELECTRIC ACTIVITY; ELECTROSTIMULATION; HYPERPOLARIZATION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOUSE; MUSCLE INNERVATION; MUSCLE RELAXATION; NERVE CELL; NERVE STIMULATION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STIMULUS RESPONSE;

ANAL CANAL; ANIMALS; DEOXYADENINE NUCLEOTIDES; ELECTRIC STIMULATION; ENZYME INHIBITORS; GENE EXPRESSION; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE RELAXATION; MYOCYTES, SMOOTH MUSCLE; NERVE FIBERS; NEURAL INHIBITION; NEUROMUSCULAR JUNCTION; NITROARGININE; PURINERGIC P2Y RECEPTOR ANTAGONISTS; TETRODOTOXIN; VASOACTIVE INTESTINAL PEPTIDE;

EID: 84875083178     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.247684     Document Type: Article

References (60)

1. Agnati LF, Zoli M, Strömberg I & Fuxe K (1995). Intercellular communication in the brain: wiring versus volume transmission. Neuroscience 69, 711-726.
2. Agoston DV, Ballmann M, Conlon JM, Dowe GH & Whittaker VP (1985). Isolation of neuropeptide-containing vesicles from the guinea pig ileum. J Neurochem 45, 398-406.
3. Bayguinov O, Keef KD, Hagen B & Sanders KM (1999). Parallel pathways mediate inhibitory effects of vasoactive intestinal polypeptide and nitric oxide in canine fundus. Br J Pharmacol 126, 1543-1552.
4. Biancani P, Walsh J & Behar J (1985). Vasoactive intestinal peptide: a neurotransmitter for relaxation of the rabbit internal anal sphincter. Gastroenterology 89, 867-874.
5. Bitar KN & Makhlouf GM (1982). Relaxation of isolated gastric smooth muscle cells by vasoactive intestinal peptide. Science 216, 531-533.
6. Boeckxstaens GE, Pelckmans PA, De Man JG, Bult H, Herman AG & Van Maercke YM (1992). Evidence for a differential release of nitric oxide and vasoactive intestinal polypeptide by nonadrenergic noncholinergic nerves in the rat gastric fundus. Arch Int Pharmacodyn Ther 318, 107-115.
7. Bryant MG, Polak MM, Modlin I, Bloom SR, Albuquerque RH & Pearse AG (1976). Possible dual role for vasoactive intestinal peptide as gastrointestinal hormone and neurotransmitter substance. Lancet 1, 991-993.
8. G-Nitro-L-arginine reduces nonadrenergic, noncholinergic relaxations of human gut. Gastroenterology 102, 679-683.
9. Burleigh DE, D'Mello A & Parks AG (1979). Responses of isolated human internal anal sphincter to drugs and electrical field stimulation. Gastroenterology 77, 484-490.
10. Burnstock G (1972). Purinergic nerves. Pharmacol Rev 24, 509-581.
11. Burnstock G (2004). Cotransmission. Curr Opin Pharmacol 4, 47-52.
12. Cheeney G, Nguyen M, Valestin J & Rao SS (2012). Topographic and manometric characterization of the recto-anal inhibitory reflex. Neurogastroenterol Motil 24, e147-e154.
13. Cobine CA, Fong M, Hamilton R & Keef KD (2007). Species dependent differences in the actions of sympathetic nerves and noradrenaline in the internal anal sphincter. Neurogastroenterol Motil 19, 937-945.
14. Colwell CS, Michel S, Itri J, Rodriguez W, Tam J, Lelievre V, Hu Z, Liu X & Waschek JA (2003). Disrupted circadian rhythms in VIP- and PHI-deficient mice. Am J Physiol Regul Integr Comp Physiol 285, R939-R949.
15. de Lorijn F, de Jonge WJ, Wedel T, Vanderwinden JM, Benninga MA & Boeckxstaens GE (2005). Interstitial cells of Cajal are involved in the afferent limb of the rectoanal inhibitory reflex. Gut 54, 1107-1113.
16. De Luca A, Li CG & Rand MJ (1999). Nitrergic and purinergic mechanisms and their interactions for relaxation of the rat internal anal sphincter. J Auton Pharmacol 19, 29-37.
17. v mouse internal anal sphincter. Neurogastroenterol Motil 24, e41-e55.
18. Eklund S, Jodal M, Lundgren O & Sjöqvist A (1979). Effects of vasoactive intestinal polypeptide on blood flow, motility and fluid transport in the gastrointestinal tract of the cat. Acta Physiol Scand 105, 461-468.
19. El-Mahmoudy A, Khalifa M, Draid M, Shiina T, Shimizu Y, El-Sayed M & Takewaki T (2006). NANC inhibitory neuromuscular transmission in the hamster distal colon. Pharmacol Res 54, 452-460.
20. Fahrenkrug J (1993). Transmitter role of vasoactive intestinal peptide. Pharmacol Toxicol 72, 354-363.
21. Fahrenkrug J (2010). VIP and PACAP. Results Probl Cell Differ 50, 221-234.
22. Fahrenkrug J, Haglund U, Jodal M, Lundgren O, Olbe L & de Muckadell OB (1978). Nervous release of vasoactive intestinal polypeptide in the gastrointestinal tract of cats: possible physiological implications. J Physiol 284, 291-305.
23. Furness JB (2006). The Enteric Nervous System Blackwell Publishing Oxford
24. Furness JB & Costa M (1979). Projections of intestinal neurons showing immunoreactivity for vasoactive intestinal polypeptide are consistent with these neurons being the enteric inhibitory neurons. Neurosci Lett 15, 199-204.
25. 1 receptors mediate inhibitory purinergic neuromuscular transmission in the human colon. Am J Physiol Gastrointest Liver Physiol 291, G584-G594.
26. Goyal RK, Rattan S & Said SI (1980). VIP as a possible neurotransmitter of non-cholinergic non-adrenergic inhibitory neurones. Nature 288, 378-380.
27. 1 receptors mediate inhibitory neuromuscular transmission in the rat colon. Br J Pharmacol 158, 1641-1652.
28. Grider JR (1989). Identification of neurotransmitters regulating intestinal peristaltic reflex in humans. Gastroenterology 97, 1414-1419.
29. Grider JR, Cable MB, Bitar KN, Said SI & Makhlouf GM (1985a). Vasoactive intestinal peptide: relaxant neurotransmitter in tenia coli of the guinea pig. Gastroenterology 89, 36-42.
30. Grider JR, Cable MB, Said SI & Makhlouf GM (1985b). Vasoactive intestinal peptide as a neural mediator of gastric relaxation. Am J Physiol Gastrointest Liver Physiol 248, G73-G78.
31. Grider JR & Makhlouf GM (1986). Colonic peristaltic reflex: identification of vasoactive intestinal peptide as mediator of descending relaxation. Am J Physiol Gastrointest Liver Physiol 251, G40-G45.
32. 2+ transients via cAMP-dependent mechanism. Am J Physiol Cell Physiol 291, C375-C385.
33. Jin JG, Murthy KS, Grider JR & Makhlouf GM (1996). Stoichiometry of neurally induced VIP release, NO formation, and relaxation in rabbit and rat gastric muscle. Am J Physiol Gastrointest Liver Physiol 271, G357-G369.
34. Jones OM, Brading AF & Mortensen NJ (2003). Role of nitric oxide in anorectal function of normal and neuronal nitric oxide synthase knockout mice: a novel approach to anorectal disease. Dis Colon Rectum 46, 963-970.
35. Keef KD, Shuttleworth CWR, Xue C, Bayguinov O, Publicover NG & Sanders KM (1994). Relationship between nitric oxide and vasoactive intestinal polypeptide in enteric inhibitory neurotransmission. Neuropharmacology 33, 1303-1314.
36. Larsson LI, Fahrenkrug J, Schaffalitzky De Muckadell O, Sundler F, Håkanson R & Rehfeld JR (1976). Localization of vasoactive intestinal polypeptide (VIP) to central and peripheral neurons. Proc Natl Acad Sci U S A 73, 3197-3200.
37. Lelievre V, Favrais G, Abad C, Adle-Biassette H, Lu Y, Germano PM, Cheung-Lau G, Pisegna JR, Gressens P, Lawson G & Waschek JA (2007). Gastrointestinal dysfunction in mice with a targeted mutation in the gene encoding vasoactive intestinal polypeptide: a model for the study of intestinal ileus and Hirschsprung's disease. Peptides 28, 1688-1699.
38. Lomax AE & Furness JB (2000). Neurochemical classification of enteric neurons in the guinea-pig distal colon. Cell Tissue Res 302, 59-72.
39. Morgado M, Cairrão E, Santos-Silva AJ & Verde I (2012). Cyclic nucleotide-dependent relaxation pathways in vascular smooth muscle. Cell Mol Life Sci 69, 247-266.
40. Mule F & Serio R (2003). NANC inhibitory neurotransmission in mouse isolated stomach: involvement of nitric oxide, ATP and vasoactive intestinal polypeptide. Br J Pharmacol 140, 431-437.
41. Nurko S & Rattan S (1988). Role of vasoactive intestinal polypeptide in the internal anal sphincter relaxation of the opossum. J Clin Invest 81, 1146-1153.
42. O'Kelly T, Brading A & Mortensen N (1993). Nerve mediated relaxation of the human internal anal sphincter: the role of nitric oxide. Gut 34, 689-693.
43. Opazo A, Lecea B, Admella C, Fantova MJ, Jiménez M, Martí-Ragué J & Clavé P (2009). A comparative study of structure and function of the longitudinal muscle of the anal canal and the internal anal sphincter in pigs. Dis Colon Rectum 52, 1902-1911.
44. Opazo A, Lecea B, Gil V, Jiménez M, Clavé P & Gallego D (2011). Specific and complementary roles for nitric oxide and ATP in the inhibitory motor pathways to rat internal anal sphincter. Neurogastroenterol Motil 23, e11-e25.
45. Qu ZD, Thacker M, Castelucci P, Bagyanszki M, Epstein ML & Furness JB (2008). Immunohistochemical analysis of neuron types in the mouse small intestine. Cell Tissue Res 334, 147-161.
46. Rae MG & Muir TC (1996). Neuronal mediators of inhibitory junction potentials and relaxation in the guinea-pig internal anal sphincter. J Physiol 493, 517-527.
47. Raghavan S, Gilmont RR, Miyasaka EA, Somara S, Srinivasan S, Teitelbaum DH & Bitar KN (2011). Successful implantation of bioengineered, intrinsically innervated, human internal anal sphincter. Gastroenterology 141, 310-319.
48. Rand MJ (1992). Nitrergic transmission: nitric oxide as a mediator of non-adrenergic, non-cholinergic neuro-effector transmission. Clin Exp Pharmacol Physiol 19, 147-169.
49. Rattan S, Regan RF, Patel CA & De Godoy MA (2005). Nitric oxide not carbon monoxide mediates nonadrenergic noncholinergic relaxation in the murine internal anal sphincter. Gastroenterology 129, 1954-1966.
50. Said SI & Mutt V (1970). Polypeptide with broad biological activity: isolation from small intestine. Science 169, 1217-1218.
51. Shimizu Y, Matsuyama H, Shiina T, Takewaki T & Furness JB (2008). Tachykinins and their functions in the gastrointestinal tract. Cell Mol Life Sci 65, 295-311.
52. 2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83, 1325-1358.
53. Sudhof TC & Malenka RC (2008). Understanding synapses: past, present, and future. Neuron 60, 469-476.
54. Takahashi T & Owyang C (1995). Vagal control of nitric oxide and vasoactive intestinal polypeptide release in the regulation of gastric relaxation in rat. J Physiol 484, 481-492.
55. Tichenor SD, Buxton IL, Johnson P, O'Driscoll K & Keef KD (2002). Excitatory motor innervation in the canine rectoanal region: role of changing receptor populations. Br J Pharmacol 137, 1321-1329.
56. Tonini M, De Giorgio R, De Ponti F, Sternini C, Spelta V, Dionigi P, Barbara G, Stanghellini V & Corinaldesi R (2000). Role of nitric oxide- and vasoactive intestinal polypeptide-containing neurones in human gastric fundus strip relaxations. Br J Pharmacol 129, 12-20.
57. Van Geldre LA & Lefebvre RA (2004). Interaction of NO and VIP in gastrointestinal smooth muscle relaxation. Curr Pharm Des 10, 2483-2497.
58. 1 purinergic receptor in guinea pig small intestine. Am J Physiol Gastrointest Liver Physiol 292, G1483-G1489.
59. 2+ currents in the guinea-pig gastric antrum by cyclic nucleotide-dependent pathways. Br J Pharmacol 146, 129-138.
60. Zizzo MG, Mulè F & Serio R (2007). Inhibitory purinergic transmission in mouse caecum: role for P2Y1 receptors as prejunctional modulators of ATP release. Neuroscience 150, 658-664.