Parallel pathways mediate inhibitory effects of vasoactive intestinal polypeptide and nitric oxide in canine fundus

British Journal of Pharmacology

Volumn 126, Issue 7, 1999, Pages 1543-1552

  Bayguinov, Orline ^a   Keef, Kathleen D ^a   Hagen, Brian ^a   Sanders, Kenton M ^a  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

Enteric nervous system; Gastric adaptive relaxation; Gastric motility; Nerves; Non adrenergic; Non cholinergic (NANC)

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ADENYLATE CYCLASE; CYCLIC GMP; FORSKOLIN; METHEMOGLOBIN; N (2 PHENYLCYCLOPENTYL)AZACYCLOTRIDECAN 2 IMINE; N ACETYL S NITROSOPENICILLAMINE; N(G) NITROARGININE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; OXYHEMOGLOBIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; ELECTROSTIMULATION; FEMALE; MALE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE RELAXATION; STOMACH FUNDUS;

EID: 0032911697     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702450     Document Type: Article

References (40)

1. BARBIER, A.J. & LEFEBVRE, R.A. (1993). Involvement of the L-arginine: nitric oxide pathway in nonadrenergic noncholinergic relaxation of the cat gastric fundus. J. Pharmacol. Exp. Ther., 266, 172-178.
2. BARNETTE, M.S., GROUS, M., TORPHY, T.J. & ORMSBEE, H.S. III. (1990). Activation of cyclic AMP-dependent protein kinase during canine lower esophageal sphincter relaxation. J. Pharmacol. Exp. Ther., 252, 1160-1166.
3. BAYGUINOV, O. & SANDERS, K.M. (1998). Dissociation between electrical and mechanical responses to nitrergic stimulation of the canine fundus. J. Physiol., 509, 437-448.
4. BITAR, K.N. & MAKHLOUF, G.M. (1982). Relaxation of isolated gastric smooth muscle cells by vasoactive intestinal peptide. Science, 216, 531-533.
5. BOECKXSTAENS, G.E., PELCKMANS, P.A., BOGERS, J.J., BULT, H., DE MAN, J.G., OOSTERBOSCH, L., HERMAN, A.G. & VAN MAERCKE, Y.M. (1990). Release of nitric oxide upon stimulation of nonadrenergic noncholinergic nerves in the rat gastric fundus. J. Pharmacol. Exp. Ther., 256, 441-447.
6. BOWMAN, A. & DRUMMOND, A.H. (1984). Cyclic GMP mediates neurogenic relaxation in the bovine retractor penis muscle. Br. J. Pharmacol., 81, 665-674.
7. BOWMAN, A. & GILLESPIE, J.S. (1982). Block of some nonadrenergic inhibitory responses of smooth muscle by a substance from haemolysed erythrocytes. J. Physiol., 328, 11-25.
8. BRADFORD, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
9. BURNS, A.J., LOMAX, A.E.J., TORIHASHI, S., SANDERS, K.M. & WARD, S.M. (1996). Interstitial cells of Cajal mediate inhibitory neurotransmission in the stomach. Proc. Natl. Acad. Sci. U.S.A., 93, 12008-12013.
10. CELLEK, S., KASAKOV, L. & MONCADA, S. (1996). Inhibition of nitrergic relaxations by a selective inhibitor of the soluble guanylate cyclase. Br. J. Pharmacol., 118, 137-140.
11. D'AMATO, M., CURRO, D., MONTUSCHI, P., CIABATTONI, G., RAGAZZONI, E. & LEFEBVRE, R.A. (1992). Release of vasoactive intestinal polypeptide from the rat gastric fundus. Br. J. Pharmacol., 105, 691-695.
12. DESAI, K.M., SESSA, W.C. & VANE, J.R. (1991). Involvement of nitric oxide in the reflex relaxation of the stomach to accomodate food or fluid. Nature, 351, 477-479.
13. DESAI, K.M., WARNER, T.D., BISHOP, A.E., POLAK, J.M. & VANE, J.R. (1994). Nitric oxide, and not vasoactive intestinal peptide, as the main neurotransmitter of vagally induced relaxation of the guinea-pig stomach. Br. J. Pharmacol., 113, 1197-1202.
14. FRANCK, H., SWEENEY, K.M., SANDERS, K.M. & SHUTTLEWORTH, C.W. (1997). Effects of a novel guanylate cyclase inhibitor on nitric oxide-dependent inhibitory neurotransmission in canine proximal colon. Br. J. Pharmacol., 122, 1223-1229.
15. GARTHWAITE, J., SOUTHAM, E., BOULTON, C.L., NIELSEN, E.B., SCHMIDT, K. & MAYER, B. (1995). Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol. Pharmacol., 48, 184-188.
16. GRIDER, J.R., CABLE, M.B., SAID, S.I. & MAKHLOUF, G.M. (1985). Vasoactive intestinal peptide as a neural mediator of gastric relaxation. Am. J. Physiol., 248, G73-G78.
17. GRIDER, J.R. & MAKHKLOUF, G.M. (1987). Prejunctional inhibition of vasoactive intestinal peptide release. Am. J. Physiol., 253, G7-G12.
18. GRIDER, J.R., MURTHY, K.S., JIN, J.G. & MAKHLOUF, G.M. (1992). Stimulation of nitric oxide from muscle cells by VIP: prejunctional enhancement of VIP release. Am. J. Physiol., 262, G774-G778.
19. GRUPP, G., GRUPP, I.L., JOHNSON, C.L., MATLIB, M.A., ROUSLIN, W., SCHWARTZ, A., WALLICK, E.T., WANG, T. & WISLER, P. (1980). Effects of RMI 12330A, a new inhibitor of adenylate cyclase on myocardial function and subcellular activity. Br. J. Pharmacol., 70, 429-442.
20. JIN, J.G., MURTHY, K.S., GRIDER, J.R. & MAKHLOUF, G.M. (1993). Activation of disinct cAMP-and cGMP-dependent pathways by relaxant agents in isolated gastric muscle cells. Am. J. Physiol., 264, G470-G477.
21. JIN, J.G., MURTHY, K.S., GRIDER, J.R & MAKHLOUF, G.M. (1996). Stoichiometry of neurally induced VIP release, NO formation, and relaxation in rabbit and rat gastric muscle. Am. J. Physiol., 271, G357-G369.
22. KOH, S.D., CAMPBELL, J.D., CARL, A. & SANDERS, K.M. (1995). Nitric oxide activates multiple potassium channels in canine colonie smooth muscle. J. Physiol., 489, 735-743.
23. LEFEBVRE, R.A. (1993). Non-adrenergic non-cholinergic neurotransmission in the proximal stomach. Gen. Pharmacol., 24, 257-266.
24. G-nitro-L-arginine on non-adrenergic non-cholinergic relaxation in the guinea-pig gastric fundus. Br. J. Pharmacol., 106, 173-179.
25. LEFEBVRE, R.A., SMITS, G.J. & TIMMERMANS, J.P. (1995). Study of NO and VIP as non-adrenergic non-cholinergic neurotransmitters in the pig gastric fundus. Br. J. Pharmacol., 116, 2017-2026.
26. LI, C.G. & RAND, M.J. (1990). Nitric oxide and vasoactive intestinal polypeptide mediate non-adrenergic, non-cholinergic inhibitory transmission to smooth muscle of the rat gastric fundus. Eur. J. Pharmacol., 191, 303-309.
27. LI, P.L., JIN, M.W. & CAMPBELL, W.B. (1998). Effect of selective inhibition of soluble guanylyl cyclase on the K(Ca) channel activity in coronary artery smooth muscle. Hypertension, 31, 303-308.
28. MASHIMO, H., HE, X.D., HUANG, P.L., FISHMAN, M.C. & GOYAL, R.K. (1996). Neuronal constitutive nitric oxide synthase is involved in murine enteric inhibitory neurotransmission. J. Clin. Invest., 98, 8-13.
29. MCLAREN, A., LI, C.G. & RAND, M.J. (1993). Mediators of nicotine-induced relaxations of the rat gastric fundus. Clin. Exp. Pharmacol. Physiol., 20, 451-457.
30. MEYER, J.H. (1987). Motility of the stomach and gastroduodenal junction. In: Physiology of Gastrointestinal Tract. 2nd edn. ed. Johnson, L.R., pp. 613-629, New York, USA, Raven Press.
31. MIRZAZADEH, S., HOBBS, A.J., TUCKER, J.F. & GIBSON, A. (1991). Cyclic nucleotide content of the rat anococcygeus during relaxations induced by drugs or by non-adrenergic, noncholinergic field stimulation. J. Pharm. Pharmacol., 43, 247-251.
32. MORLEY, D. & KEEPER, L.K. (1993). Nitric oxide/nucleophile complexes: a unique class of nitric oxide-based vasodilators. J. Cardiovasc. Pharmacol., 22 (suppl 7): S3-S9.
33. MORO, M.A., RUSSEL, R.J., CELLEK, S., LIZASOAIN, I., SU, Y., DARLEY-USMAR, V.M., RADOMSKI, M.W. & MONCADA, S. (1996). cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase. Proc. Natl. Acad. Sci. U.S.A., 93, 1480-1485.
34. MURTHY, K.S., JIN, G.J. & MAKHLOUF, G.M. (1994). Inhibition of nitric oxide synthase activity in dispersed gastric muscle cells by protein kinase C. Am. J. Physiol., 266, G161-G1615.
35. MURTHY, K.S. & MAKHLOUF, G.M. (1995). Interaction of cA-kinase and cG-kinase in mediating relaxation of dispersed smooth muscle cells. Am. J. Physiol., 268, C171-C180.
36. PATON, W.D.M. & VANE, J.R. (1963). An analysis of the responses of the isolated stomach to electrical stimulation and to drugs. J. Physiol., 165, 10-46.
37. PFEIFER, A., KLATT, P., MASSBERG, S., NY, L., SAUSBIER, M., HIRNEISS, C., WANG, G.X., KORTH, M., ASZODI, A., ANDERSSON, K.E., KROMBACH, F., MAYERHOFER, A., RUTH, P., FASSLER, R. & HOFMANN, F. (1998). Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO J., 17, 3045-3051.
38. SATAKE, N., SHIBATA, M. & SHIBATA, S. (1996). The inhibitory effects of iberiotoxin and 4-aminopyridine on the relaxation induced by beta I-and beta 2-adrenoceptor activation in rat aortic rings. Br. J. Pharmacol., 119, 505-510.
39. SHUTTLEWORTH, C.W., KOH, S.D., BAYGINOV, O. & SANDERS, K.M. (1996). Activation of delayed rectifier potassium channels in canine proximal colon by vasoactive intestinal peptide. J. Physiol., 493, 651-663.
40. TORPHY, T.J., FINE, C.F., BURMAN, M., BARNETTE, M.S. & ORMSBEE, H.S. (1986). Lower esophageal sphincter relaxation is associated with increased cyclic nucleotide content. Am. J. Physiol., 251, G786-G793.