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Volumn 63, Issue , 2013, Pages 457-467

Synthesis, biological activity and resistance to proteolytic digestion of new cyclic dermorphin/deltorphin analogues

(14) Bańkowski, Krzysztof a Witkowska, Ewa b Michalak, Olga M a Sidoryk, Katarzyna a Szymanek, Ewa a Antkowiak, Bozena c Paluch, Małgorzata c Filip, Katarzyna E a Cebrat, Marek d Setner, Bartosz d Szewczuk, Zbigniew d Stefanowicz, Piotr d Cmoch, Piotr a,e Izdebski, Jan a,b

a INDUSTRIAL CHEMISTRY RESEARCH INSTITUTE (Poland)

b UNIVERSITY OF WARSAW (Poland)

c MILITARY INSTITUTE OF HYGIENE AND EPIDEMIOLOGY (Poland)

d UNIVERSITY OF WROC AW (Poland)

e INSTITUTE OF ORGANIC CHEMISTRY (Poland)

Author keywords

Antinociceptive effect; Cyclic opioid peptides; Dermorphin deltorphin analogues; Peptide synthesis; Stability to proteolytic enzymes

Indexed keywords

ANTINOCICEPTIVE AGENT; CHYMOTRYPSIN; DELTORPHIN; DERMORPHIN DERIVATIVE; MORPHINE; PEPSIN A; TETRAPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; HOT PLATE TEST; IN VITRO STUDY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PROTEIN DEGRADATION; TAIL FLICK TEST;

ANALGESICS, OPIOID; ANIMALS; CHYMOTRYPSIN; HOT TEMPERATURE; HYDROLYSIS; HYPERALGESIA; INDOLES; MALE; MICE; MICE, INBRED BALB C; MODELS, CHEMICAL; MOLECULAR STRUCTURE; OLIGOPEPTIDES; OPIOID PEPTIDES; PEPSIN A; PROTEOLYSIS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STYRENES;

EID: 84875082272 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2013.02.019 Document Type: Article

Times cited : (11)

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