Potent side-chain to side-chain cyclized dermorphin analogues containing a carbonyl bridge

Journal of Peptide Science

Volumn 9, Issue 10, 2003, Pages 649-657

  Filip, Katarzyna ^a   Oleszczuk, Marta ^b   Pawlak, Danuta ^a   Wójcik, Jacek ^b   Chung, Nga N ^c   Schiller, Peter W ^c   Izdebski, Jan ^a  

^a UNIVERSITY OF WARSAW   (Poland)

^b INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^c CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

Conformation; Cyclic opioid peptides; EDMC; NMR; Side chain to side chain cyclization; Solid phase synthesis; Structure activity relationship

Indexed keywords

BRIDGED COMPOUND; CARBONYL DERIVATIVE; DELTORPHIN; DELTORPHIN DERIVATIVE; DERMORPHIN; DERMORPHIN DERIVATIVE; ENKEPHALIN DERIVATIVE; LYSINE; OPIATE PEPTIDE; PHENYLALANINE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG POTENCY; GUINEA PIG; ILEUM; INTERMETHOD COMPARISON; MONTE CARLO METHOD; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; SOLID; STRUCTURE ACTIVITY RELATION; VAS DEFERENS;

ANALGESICS, OPIOID; ANIMALS; GUINEA PIGS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; OLIGOPEPTIDES; OPIOID PEPTIDES; PEPTIDES, CYCLIC; PROTEIN CONFORMATION; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU;

CAVIA PORCELLUS; SUS SCROFA;

EID: 0242363134     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/psc.510     Document Type: Article

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