A non-electrolyte haemolysis assay for diagnosis and prognosis of sickle cell disease

Journal of Physiology

Volumn 591, Issue 6, 2013, Pages 1463-1474

  Milligan, C ^a   Rees, D C ^b   Ellory, J C ^c   Osei, A ^b   Browning, J A ^c   Hannemann, A ^a   Gibson, J S ^a  

^a Department of Veterinary Medicine ^*  (United Kingdom)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ARABINOSE; CYTOCHALASIN B; ERYTHRITOL; HEMOGLOBIN BETA CHAIN; HEMOGLOBIN F; HEMOGLOBIN S; MANNITOL; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SUCROSE;

ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DEOXYGENATION; DIAGNOSTIC TEST; ERYTHROCYTE MEMBRANE; HUMAN; HUMAN CELL; ION TRANSPORT; LOW TEMPERATURE; LYSIS; NON ELECTROLYTE HEMOLYSIS ASSAY; OSMOLALITY; OXYGEN SATURATION; PH; PRIORITY JOURNAL; PROGNOSIS; PROTEIN POLYMERIZATION; SICKLE CELL ANEMIA;

ALDEHYDES; ANEMIA, SICKLE CELL; CELL MEMBRANE; CYTOCHALASIN B; ERYTHROCYTES, ABNORMAL; HEMATOLOGIC TESTS; HEMOGLOBINS; HEMOLYSIS; HUMANS; HYDROGEN-ION CONCENTRATION; POLYMERIZATION; PROGNOSIS; SUCROSE; TEMPERATURE; UREA;

EID: 84875058576     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.246579     Document Type: Article

References (47)

1. Abraham DJ, Mehanna AS, Wireko FC, Whitney J, Thomas RP & Orringer EP (1991). Vanillin, a potential agent for the treatment of sickle cell anemia. Blood 77, 1334-1341.
2. Ataga KI, Reid M, Ballas SK, Yasin Z, Bigelow C, St. James L, Smith WR, Galacteros F, Kutlar A, Hull JH & Stockler JW (2011). Improvements in haemolysis and indicators of erythrocyte survival do not correlate with acute vaso-occlusive crises in patients with sickle cell disease: a phase III randomised, placebo-controlled, double-blind study of the gardos channel blocker senicapoc (ICA-17043). Br J Haematol 153, 92-104.
3. Bernhardt I, Hall AC & Ellory JC (1991). Effects of low ionic strength media on passive human red cell monovalent cation transport. J Physiol 434, 489-506.
4. + exchange in human erythrocytes activated under low ionic strength conditions. Blood Cells Mol Dis 27, 108-111.
5. Blackstock EJ & Stewart GW (1986). The dependence on external cation of sodium and potassium fluxes across the human red cell membrane at low temperatures. J Physiol 375, 403-420.
6. Bookchin RM & Lew VL (1981). Effect of a 'sickling pulse' on calcium and potassium transport in sickle red cells. J Physiol 312, 265-280.
7. Bridges KR, Barabino GA, Brugnara C, Cho MR, Dover CG, Ewenstein BM, Golan DE, Guttmann CRG, Hofrichter J, Mulkern RV, Zhang B & Eaton WA, (1996). A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy. Blood 88, 4701-4710.
8. Browning JA, Robinson HC, Ellory JC & Gibson JS (2007). Deoxygenation-induced non-electrolyte pathway in red cells from sickle cell patients. Cell Physiol Biochem 19, 165-174.
9. + channel by clotrimazole. Ann N Y Acad Sci 763, 262-271.
10. Bunn HF, Noguchi CT, Hofrichter J, Schechter GP, Schechter AN & Eaton WA (1982). Molecular and cellular pathogenesis of hemoglobin SC disease. Proc Natl Acad Sci U S A 79, 7527-7531.
11. Canning DM & Huntsman RG (1970). An assessment of sickledex as an alternative to the sickling test. J Clin Pathol 23, 736-737.
12. Charache S, Dover GJ, Moyer MA & Moore JW (1987). Hydroxyurea-induced augmentation of fetal haemoglobin production in patients with sickle cell anemia. Blood 69, 109-116.
13. Clark MR, Mohandas N & Shohet SB (1982). Hydration of sickle cells using the sodium ionophore monensin. J Clin Invest 70, 1074-1080.
14. Clark MR & Rossi ME (1990). Permeability characteristics of deoxygenated sickle cells. Blood 76, 2139-2145.
15. Cohen CM, Jackson PL & Branton D (1978). Actin-membrane interactions: association of G-actin with the red cell. J Supramol Struct 9, 113-124.
16. Dalibalta S, Ellory JC, Browning JA, Wilkins RJ, Rees DC & Gibson JS (2010). Novel permeability characteristics of red blood cells from sickle cell patients. Blood Cells Mol Dis 45, 46-52.
17. Dunham PB & Ellory JC (1981). Passive potassium transport in low potassium sheep red cells: dependence upon cell volume and chloride. J Physiol 318, 511-530.
18. Eaton JW & Hofrichter J (1987). Hemoglobin S gelation and sickle cell disease. Blood 70, 1245-1266.
19. Ellory JC, Sequeira R, Constantine A, Wilkins RJ & Gibson JS (2008). Non-electrolyte permeability of deoxygenated sickle cells compared. Blood Cells Mol Dis 41, 44-49.
20. Estensen RD & Plageman PGW (1972). Cytochalasin B: inhibition of glucose and glucosamine transport. Proc Natl Acad Sci U S A 69, 1430-1434.
21. Galkin O, Nagel RL & Vekilov PG (2007). The kinetics of nucleation and growth of sickle cell hemoglobin fibres. J Mol Biol 365, 425-439.
22. Gardos G (1958). The function of calcium and potassium permeability of human erythrocytes. Biochim Biophys Acta 30, 653-654.
23. Gibson JS & Ellory JC (2002). Membrane transport in sickle cell disease. Blood Cells Mol Dis 28, 1-12.
24. Joiner CH (1993). Cation transport and volume regulation in sickle red blood cells. Am J Physiol 264, C251-C270.
25. Joiner CH, Dew A & Ge DL (1988). Deoxygenation-induced fluxes in sickle cells. I. Relationship between net potassium efflux and net sodium influx. Blood Cells 13, 339-348.
26. Joiner CH, Morris CL & Cooper ES (1993). Deoxygenation-induced cation fluxes in sickle cells. III. Cation selectivity and response to pH and membrane potential. Am J Physiol 264, C734-C744.
27. Lew VL & Bookchin RM (2005). Ion transport pathology in the mechanism of sickle cell dehydration. Physiol Rev 85, 179-200.
28. 2+ permeability. J Clin Invest 99, 2727-2735.
29. Ma Y-L, Rees DC, Gibson JS & Ellory JC (2012). The conductance of red blood cells from sickle cell patients: ion selectivity and inhibitors. J Physiol 590, 2095-2105.
30. Makhatadze G & Privalov PL (1992). Protein interactions with urea and guanidinium chloride. J Mol Biol 33, 491-497.
31. Mohandas N, Rossi ME & Clark MR (1986). Association between morphologic distortion of sickle cells and deoxygenation-induced cation permeability increases. Blood 68, 450-454.
32. Ohene-Frempong K, Weiner SJ, Sleeper LA, Miller ST, Embury S, Moohr JW, Wethers DL, Pegelow CH & Gill FM (1998). Cerebrovascular accidents in sickle cell disease: rates and risk factors. Blood 91, 288-294.
33. Pedersen SF, Hoffmann EK & Mills JW (2001). The cytoskeleton and cell volume regulation. Comp Biochem Physiol A 130, 385-399.
34. Platt OS, Brambilla DJ, Rosse WF, Milner PF, Castro O, Steinberg MH & Klug PP (1994). Mortality in sickle cell disease: life expectancy and risk factors for early death. N Engl J Med 330, 1639-1644.
35. Platt OS, Thorington BD, Brambilla DJ, Milner PFA, Rosse WF, Vichinsky E & Kinney TR (1991). Pain in sickle cell disease. Rates and risk factors. N Engl J Med 325, 11-16.
36. Rees DC, Williams TN & Gladwin MT (2010). Sickle-cell disease. Lancet 376, 2018-2031.
37. Rodriguez GI, Kuhn JG, Weiss GR, Hilsenbeck SG, Eckardt JR, Thurman A, Rinaldi DA, Hodges S, Von Hoff DD & Rowinsky EK (1998). A bioavailability and pharmacokinetic study of oral and intravenous hydroxyurea. Blood 91, 1533-1541.
38. Rodgers GP, Dover GJ, Noguchi CT, Schechter AN & Nienhuis AW (1990). Hematologic responses of patients with sickle cell disease to treatment with hydroxyurea. N Engl J Med 322, 1037-1045.
39. Rosa R, Bierer BA, Thomas R, Stoff JS, Kruskall M, Robinson S, Bunn HF & Epstein FH (1980). A study of hyponatremia in the prevention and treatment of sickle-cell crisis. N Engl J Med 303, 1138-1143.
40. Speake PF, Roberts CA & Gibson JS (1997). Effect of changes in respiratory blood parameters on equine red blood cell K-Cl cotransporter. Am J Physiol 273, C1811-C1818.
41. Steinberg MH, Long Z-H, Barton FB, Terrin ML, Charache S & Dover GJ (1997). Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Blood 89, 1078-1088.
42. Steinberg MH, Forget BG, Higgs DR & Nagel RL eds (2001). Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical Management Cambridge University Press, Cambridge
43. Stocker JW, De Franceschi LD, McNaughton-Smith GA, Corrocher R, Beuzard Y & Brugnara C (2003). ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice. Blood 101, 2412-2418.
44. Stuart MJ & Nagel RL (2004). Sickle-cell disease. Lancet 364, 1343-1360.
45. Theodoropoulos PA, Gravanis A, Tsapara A, Margioris AN, Papadogiorgaki E, Galanopoulos V & Stournaras C (1994). Cytochalasin B may shorten actin filaments by a mechanism independent of barbed end capping. Biochem Pharmacol 47, 1875-1881.
46. Vichinsky EP, Neumayr LD, Earles AN, Williams R, Lennette ET, Dean D, Nickerson B, Orringer E, McKie V, Bellevue R, Daeschner C & Manci EA (2000). Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. N Engl J Med 342, 1855-1865.
47. Zaugg RH, Walder JA & Klotz IM (1977). Schiff base adducts of hemoglobin. Modifications that inhibit erythrocyte sickling. J Biol Chem 252, 8542-8548.