A novel method for detecting 7-methyl guanine reveals aberrant methylation levels in Huntington disease

Analytical Biochemistry

Volumn 436, Issue 2, 2013, Pages 112-120

  Thomas, Beena ^a   Matson, Samantha ^b   Chopra, Vanita ^b,c   Sun, Liping ^a   Sharma, Swati ^a   Hersch, Steven ^b,c   Diana Rosas, H ^c   Scherzer, Clemens ^c,d   Ferrante, Robert ^a,e   Matson, Wayne ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

7 Methyl guanine (7 MG); Electrochemical detection (ECD); Guanine (G); Huntington disease (HD)

Indexed keywords

CELL PROLIFERATION; CHEMICAL DETECTION; ELECTROCHEMICAL SENSORS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHYLATION; NEURODEGENERATIVE DISEASES; NUCLEIC ACIDS; POSITIVE IONS;

7-METHYL GUANINE (7-MG); BIOLOGICAL FUNCTIONS; ELECTROCHEMICAL DETECTION; GUANINE; HUNTINGTON DISEASE; PATHOLOGICAL CONDITIONS; TRANSCRIPTIONAL DYSREGULATION; TRANSCRIPTIONAL REGULATION;

ALKYLATION;

7 METHYLGUANINE;

ANIMAL TISSUE; ARTICLE; CALIBRATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; ELECTROCHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUNTINGTON CHOREA; METHYLATION; MOTOR CORTEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

MUS MUSCULUS;

EID: 84875046091     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.01.035     Document Type: Article

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