Development of whole-virus multiplex luminex-based serological assays for diagnosis of infections with kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 homologs in macaques

Clinical and Vaccine Immunology

Volumn 20, Issue 3, 2013, Pages 409-419

  Ryan, Jonathan T ^a   Rose, Timothy M ^a,b  

^a SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIBODY; VIRUS ANTIGEN; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ANTIGEN ANTIBODY REACTION; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN HERPESVIRUS 8; IMMUNE RESPONSE; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; KAPOSI SARCOMA; MACACA; MALE; MIXED INFECTION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REFERENCE VALUE; SERODIAGNOSIS; SEROPREVALENCE; VIRION; VIRUS CELL INTERACTION; VIRUS REACTIVATION; WHOLE VIRUS MULTIPLEX LUMINEX BASED SEROLOGICAL ASSAY;

ANIMALS; ANIMALS, ZOO; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 8, HUMAN; MACACA; NEPOVIRUS; PRIMATE DISEASES; SEROEPIDEMIOLOGIC STUDIES; SEROLOGIC TESTS;

EID: 84875008963     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00673-12     Document Type: Article

References (41)

1. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS. 1994. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 266:1865-1869.
2. Antman K, Chang Y. 2000. Kaposi's sarcoma. N. Engl. J. Med. 342:1027-1038.
3. Russo JJ, Bohenzky RA, Chien MC, Chen J, Yan M, Maddalena D, Parry JP, Peruzzi D, Edelman IS, Chang Y, Moore PS. 1996. Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc. Natl. Acad. Sci. U. S. A. 93:14862-14867.
4. Simpson GR, Schulz TF, Whitby D, Cook PM, Boshoff C, Rainbow L, Howard MR, Gao SJ, Bohenzky RA, Simmonds P, Lee C, de Ruiter A, Hatzakis A, Tedder RS, Weller IV, Weiss RA, Moore PS. 1996. Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. Lancet 348:1133-1138.
5. Pau CP, Lam LL, Spira TJ, Black JB, Stewart JA, Pellett PE, Respess RA. 1998. Mapping and serodiagnostic application of a dominant epitope within the human herpesvirus 8 ORF 65-encoded protein. J. Clin. Microbiol. 36:1574-1577.
6. Katano H, Iwasaki T, Baba N, Terai M, Mori S, Iwamoto A, Kurata T, Sata T. 2000. Identification of antigenic proteins encoded by human herpesvirus 8 and seroprevalence in the general population and among patients with and without Kaposi's sarcoma. J. Virol. 74:3478-3485.
7. Mbisa GL, Miley W, Gamache CJ, Gillette WK, Esposito D, Hopkins R, Busch MP, Schreiber GB, Little RF, Yarchoan R, Ortiz-Conde BA, Labo N, Whitby D. 2010. Detection of antibodies to Kaposi's sarcomaassociated herpesvirus: a new approach using K8.1 ELISA and a newly developed recombinant LANA ELISA. J. Immunol. Methods 356:39-46.
8. Engels EA, Sinclair MD, Biggar RJ, Whitby D, Ebbesen P, Goedert JJ, Gastwirth JL. 2000. Latent class analysis of human herpesvirus 8 assay performance and infection prevalence in sub-Saharan Africa and Malta. Int. J. Cancer 88:1003-1008.
9. Sergerie Y, Abed Y, Roy J, Boivin G. 2004. Comparative evaluation of three serological methods for detection of human herpesvirus 8-specific antibodies in Canadian allogeneic stem cell transplant recipients. J. Clin. Microbiol. 42:2663-2667.
10. Nascimento MC, de Souza VA, Sumita LM, Freire W, Munoz F, Kim J, Pannuti CS, Mayaud P. 2007. Comparative study of Kaposi's sarcomaassociated herpesvirus serological assays using clinically and serologically defined reference standards and latent class analysis. J. Clin. Microbiol. 45:715-720.
11. Pellett PE, Wright DJ, Engels EA, Ablashi DV, Dollard SC, Forghani B, Glynn SA, Goedert JJ, Jenkins FJ, Lee TH, Neipel F, Todd DS, Whitby D, Nemo GJ, Busch MP. 2003. Multicenter comparison of serologic assays and estimation of human herpesvirus 8 seroprevalence among US blood donors. Transfusion 43:1260-1268.
12. Albrecht D, Meyer T, Lorenzen T, Stoehr A, Arndt R, Plettenberg A. 2004. Epidemiology of HHV-8 infection in HIV-positive patients with and without Kaposi sarcoma: diagnostic relevance of serology and PCR. J. Clin. Virol. 30:145-149.
13. Laney AS, Peters JS, Manzi SM, Kingsley LA, Chang Y, Moore PS. 2006. Use of a multiantigen detection algorithm for diagnosis of Kaposi's sarcomaassociated herpesvirus infection. J. Clin. Microbiol. 44:3734-3741. 14. Burbelo PD, Leahy HP, Groot S, Bishop LR, Miley W, Iadarola MJ, Whitby D, Kovacs JA. 2009. Four-antigen mixture containing v-cyclin for serological screening of human herpesvirus 8 infection. Clin. Vaccine Immunol. 16:621-627.
14. Zheng D, Wan J, Cho YG, Wang L, Chiou CJ, Pai S, Woodard C, Zhu J, Liao G, Martinez-Maza O, Qian J, Zhu H, Hayward GS, Ambinder RF, Hayward SD. 2011. Comparison of humoral immune responses to Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus using a viral proteome microarray. J. Infect. Dis. 204:1683-1691.
15. Rose TM, Strand KB, Schultz ER, Schaefer G, Rankin GW, Jr., Thouless ME, Tsai CC, Bosch ML. 1997. Identification of two homologs of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in retroperitoneal fibromatosis of different macaque species. J. Virol. 71:4138-4144.
16. Bruce AG, Bakke AM, Bielefeldt-Ohmann H, Ryan JT, Thouless ME, Tsai CC, Rose TM. 2006. High levels of retroperitoneal fibromatosis (RF)-associated herpesvirus in RF lesions in macaques are associated with ORF73 LANA expression in spindleoid tumour cells. J. Gen. Virol. 87: 3529-3538.
17. Bielefeldt-Ohmann H, Barouch DH, Bakke AM, Bruce AG, Durning M, Grant R, Letvin NL, Ryan JT, Schmidt A, Thouless ME, Rose TM. 2005. Intestinal stromal tumors in a simian immunodeficiency virus-infected, simian retrovirus-2 negative rhesus macaque (Macaca mulatta). Vet. Pathol. 42:391-396.
18. Burnside KL, Ryan JT, Bielefeldt-Ohmann H, Gregory Bruce A, Thouless ME, Tsai CC, Rose TM. 2006. RFHVMn ORF73 is structurally related to the KSHV ORF73 latency-associated nuclear antigen (LANA) and is expressed in retroperitoneal fibromatosis (RF) tumor cells. Virology 354:103-115.
19. Desrosiers RC, Sasseville VG, Czajak SC, Zhang X, Mansfield KG, Kaur A, Johnson RP, Lackner AA, Jung JU. 1997. A herpesvirus of rhesus monkeys related to the human Kaposi's sarcoma-associated herpesvirus. J. Virol. 71:9764-9769.
20. Alexander L, Denekamp L, Knapp A, Auerbach MR, Damania B, Desrosiers RC. 2000. The primary sequence of rhesus monkey rhadinovirus isolate 26-95: sequence similarities to Kaposi's sarcoma-associated herpesvirus and rhesus monkey rhadinovirus isolate 17577. J. Virol. 74: 3388-3398.
21. Searles RP, Bergquam EP, Axthelm MK, Wong SW. 1999. Sequence and genomic analysis of a rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8. J. Virol. 73: 3040-3053.
22. Rose TM. 2005. CODEHOP-mediated PCR-a powerful technique for the identification and characterization of viral genomes. Virol. J. 2:20.
23. Schultz ER, Rankin GW, Jr., Blanc MP, Raden BW, Tsai CC, Rose TM. 2000. Characterization of two divergent lineages of macaque rhadinoviruses related to Kaposi's sarcoma-associated herpesvirus. J. Virol. 74: 4919-4928.
24. Greensill J, Sheldon JA, Renwick NM, Beer BE, Norley S, Goudsmit J, Schulz TF. 2000. Two distinct gamma-2 herpesviruses in African green monkeys: a second gamma-2 herpesvirus lineage among old world primates? J. Virol. 74:1572-1577.
25. Bruce AG, Bakke AM, Thouless ME, Rose TM. 2005. Development of a real-time QPCR assay for the detection of RV2 lineage-specific rhadinoviruses in macaques and baboons. Virol. J. 2:2.
26. White JA, Todd PA, Yee JL, Kalman-Bowlus A, Rodgers KS, Yang X, Wong SW, Barry P, Lerche NW. 2009. Prevalence of viremia and oral shedding of rhesus rhadinovirus and retroperitoneal fibromatosis herpesvirus in large age-structured breeding groups of rhesus macaques (Macaca mulatta). Comp. Med. 59:383-390.
27. Wong SW, Bergquam EP, Swanson RM, Lee FW, Shiigi SM, Avery NA, Fanton JW, Axthelm MK. 1999. Induction of B cell hyperplasia in simian immunodeficiency virus-infected rhesus macaques with the simian homologue of Kaposi's sarcoma-associated herpesvirus. J. Exp. Med. 190: 827-840.
28. Barcy S, De Rosa SC, Vieira J, Diem K, Ikoma M, Casper C, Corey L. 2008. Gamma delta-T cells involvement in viral immune control of chronic human herpesvirus 8 infection. J. Immunol. 180:3417-3425.
29. Bruce AG, Bakke AM, Gravett CA, DeMaster LK, Bielefeldt-Ohmann H, Burnside KL, Rose TM. 2009. The ORF59 DNA polymerase processivity factor homologs of Old World primate RV2 rhadinoviruses are highly conserved nuclear antigens expressed in differentiated epithelium in infected macaques. Virol. J. 6:205.
30. Kuller L, Watanabe R, Anderson D, Grant R. 2005. Development of a whole-virus multiplex flow cytometric assay for antibody screening of a specific pathogen-free primate colony. Diagn. Microbiol. Infect. Dis. 53: 185-193.
31. Dias D, Van Doren J, Schlottmann S, Kelly S, Puchalski D, Ruiz W, Boerckel P, Kessler J, Antonello JM, Green T, Brown M, Smith J, Chirmule N, Barr E, Jansen KU, Esser MT. 2005. Optimization and validation of a multiplexed Luminex assay to quantify antibodies to neutralizing epitopes on human papillomaviruses 6, 11, 16, and 18. Clin. Diagn. Lab. Immunol. 12:959-969.
32. Rose TM, Ryan JT, Schultz ER, Raden BW, Tsai CC. 2003. Analysis of 4.3 kilobases of divergent locus B of macaque retroperitoneal fibromatosis- associated herpesvirus reveals a close similarity in gene sequence and genome organization to Kaposi's sarcoma-associated herpesvirus. J. Virol. 77:5084-5097.
33. White JA, Yang X, Todd PA, Lerche NW. 2011. Longitudinal patterns of viremia and oral shedding of rhesus rhadinovirus and retroperitoneal fibromatosis herpesviruses in age-structured captive breeding populations of rhesus macaques (Macaca mulatta). Comp. Med. 61:60-70.
34. Boshoff C, Schulz TF, Kennedy MM, Graham AK, Fisher C, Thomas A, McGee JO, Weiss RA, O'Leary JJ. 1995. Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells. Nat. Med. 1:1274-1278.
35. Bechtel JT, Liang Y, Hvidding J, Ganem D. 2003. Host range of Kaposi's sarcoma-associated herpesvirus in cultured cells. J. Virol. 77:6474-6481. 37. Bruce AG, Bielefeldt-Ohmann H, Barcy S, Bakke AM, Lewis P, Tsai CC, Murnane RD, Rose TM. 2012. Macaque homologs of EBV and KSHV show uniquely different associations with simian AIDS-related lymphomas. PLoS Pathog. 8:e1002962. doi:10.1371/journal.ppat.1002962.
36. Coscoy L, Ganem D. 2000. Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display ofMHCclass I chains by enhancing their endocytosis. Proc. Natl. Acad. Sci. U. S. A. 97:8051-8056.
37. Harris S, Lang SM, Means RE. 2010. Characterization of the rhesus fibromatosis herpesvirus MARCH family member rfK3. Virology 398: 214-223.
38. Casper C, Krantz E, Taylor H, Dalessio J, Carrell D, Wald A, Corey L, Ashley R. 2002. Assessment of a combined testing strategy for detection of antibodies to human herpesvirus 8 (HHV-8) in persons with Kaposi's sarcoma, persons with asymptomatic HHV-8 infection, and persons at low risk for HHV-8 infection. J. Clin. Microbiol. 40:3822-3825.
39. Okroj M, Tedeschi R, Mancuso R, Brambilla L, Tourlaki A, Dillner J, Blom AM. 2011. Prevalence of antibodies against Kaposi's sarcoma associated herpes virus (KSHV) complement inhibitory protein (KCP) in KSHV-related diseases and their correlation with clinical parameters. Vaccine 29:1129-1134.
40. Anderson S, Wakeley P, Wibberley G, Webster K, Sawyer J. 2011. Development and evaluation of a Luminex multiplex serology assay to detect antibodies to bovine herpes virus 1, parainfluenza 3 virus, bovine viral diarrhoea virus, and bovine respiratory syncytial virus, with comparison to existing ELISA detection methods. J. Immunol. Methods 366:79-88.
41. Piriou E, Kimmel R, Chelimo K, Middeldorp JM, Odada PS, Ploutz-Snyder R, Moormann AM, Rochford R. 2009. Serological evidence for long-term Epstein-Barr virus reactivation in children living in a holoendemic malaria region of Kenya. J. Med. Virol. 81:1088-1093.