Maintaining functional islets through encapsulation in an injectable saccharide-peptide hydrogel

Biomaterials

Volumn 34, Issue 16, 2013, Pages 3984-3991

  Liao, Sophia W ^a   Rawson, Jeffrey ^a   Omori, Keiko ^a   Ishiyama, Kohei ^a   Mozhdehi, Davoud ^b   Oancea, Alina R ^a   Ito, Taihei ^a   Guan, Zhibin ^b   Mullen, Yoko ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

3D islet culture; Diabetes; Extrahepatic islet transplantation; Hydrogel; Tissue engineering

Indexed keywords

3D STRUCTURE; EXPOSED TO; IN-SITU POLYMERIZATION; INSULIN RELEASE; ISLET TRANSPLANTATION; PERIPHERAL BLOOD MONONUCLEAR CELLS; SYNTHETIC SCAFFOLDS; TYPE 1 DIABETES;

BIOCOMPATIBILITY; INSULIN; MEDICAL PROBLEMS; PEPTIDES; RAT CONTROL; RATS; THREE DIMENSIONAL COMPUTER GRAPHICS; TISSUE ENGINEERING;

HYDROGELS;

BIOMATERIAL; MESSENGER RNA; SACCHARIDE PEPTIDE HYDROGEL; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CELL FUNCTION; CELL INFILTRATION; CONTROLLED STUDY; ENCAPSULATION; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; LEWIS RAT; MALE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PERIPHERAL BLOOD MONONUCLEAR CELL; PERITONEAL BIOPSY; PRIORITY JOURNAL; RAT; THREE DIMENSIONAL IMAGING;

ANIMALS; BIOCOMPATIBLE MATERIALS; CARBOHYDRATES; HYDROGEL; INJECTIONS; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; LIVER; LUMINESCENCE; MALE; MATERIALS TESTING; PEPTIDES; RATS; RATS, INBRED LEW; SOLUBILITY; TISSUE CULTURE TECHNIQUES; TISSUE SURVIVAL;

RATTUS;

EID: 84874976598     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.02.007     Document Type: Article

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